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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:panic disorder
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Accession:DOID:594 term browser browse the term
Definition:An anxiety disorder that is characterized by unexpected and repeated episodes of intense fear accompanied by physical symptoms that may include chest pain, heart palpitations, shortness of breath, dizziness, or abdominal distress. (DO)
Synonyms:exact_synonym: Panic Attack;   Panic Attacks;   Panic Disorders;   panic anxiety syndrome
 narrow_synonym: PAND1;   PAND2;   PAND3;   panic disorder 1;   panic disorder 2;   panic disorder 3;   panic disorder with joint laxity;   panic disorder without agoraphobia
 related_synonym: PANIC DISORDER SUSCEPTIBILITY LOCUS, CHROMOSOME 13q-RELATED;   PANIC DISORDER SUSCEPTIBILITY LOCUS, CHROMOSOME 4q-RELATED;   PANIC DISORDER SUSCEPTIBILITY LOCUS, CHROMOSOME 9q-RELATED;   catechol-o-methyltransferase polymorphism
 primary_id: MESH:D016584
 alt_id: OMIM:167870;   OMIM:607853;   OMIM:609985
 xref: EFO:0004262;   EFO:1001907;   ICD10CM:F41.0;   NCI:C34890;   OMIM:PS167870
For additional species annotation, visit the Alliance of Genome Resources.


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panic disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor ISO GAD PMID:15118671 RGD:1331525 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Adora2a adenosine A2a receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12825092 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Adra2a adrenoceptor alpha 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:14656453 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Cckbr cholecystokinin B receptor ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:8878350 PMID:15354400 RGD:1358454 NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881 		JBrowse link
G Comt catechol-O-methyltransferase ISO ClinVar Annotator: match by term: CATECHOL-O-METHYLTRANSFERASE POLYMORPHISM
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD		 PMID:7304673 PMID:7585135 PMID:8807664 PMID:8886163 PMID:8941353 More... NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Crh corticotropin releasing hormone ISO RGD PMID:14675801 RGD:1358525 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A IMP
ISO		 RGD PMID:21421022 PMID:20817074 RGD:5683630, RGD:5683631 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Ins2 insulin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12073167 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Manea mannosidase, endo-alpha susceptibility ISO associated with substance dependence; DNA:SNP:3'utr: (rs1133503) (Human) RGD PMID:24473444 RGD:401851911 NCBI chr 5:40,196,373...40,218,540
Ensembl chr 5:40,196,396...40,218,459 		JBrowse link
G Maoa monoamine oxidase A ISO RGD PMID:15670397 RGD:1600723 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593 		JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO DNA:polymorphism: : RGD PMID:24856568 RGD:12910826 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Tph2 tryptophan hydroxylase 2 susceptibility ISO DNA:SNP:intron: (rs1386494) (human) RGD PMID:17123728 RGD:5686356 NCBI chr 7:50,685,694...50,789,424
Ensembl chr 7:50,685,694...50,789,424 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18969
    disease of anatomical entity 18249
      nervous system disease 14090
        central nervous system disease 12430
          brain disease 11668
            disease of mental health 8318
              cognitive disorder 2303
                anxiety disorder 181
                  panic disorder 12
                    Panic Disorder with Bladder Conditions 0
                    Panic Disorder with Joint Laxity 0
                    panic disorder with agoraphobia + 0
paths to the root