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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:immunosuppressive agent
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Accession:CHEBI:35705 term browser browse the term
Definition:An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
Synonyms:related_synonym: immunosuppressant;   immunosuppressive agents;   inmunosupresor


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Your selection has 13923 annotated objects. The maximum number of objects that can be shown is 2000. The list is too large to display.

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    • Term paths to the root
    Path 1
    Term Annotations click to browse term
      CHEBI ontology 19808
        role 19784
          biological role 19782
            immunomodulator 15051
              immunosuppressive agent 13923
                (+)-dexrazoxane + 176
                4'-demethyldeoxypodophyllotoxin 0
                4-hydroperoxycyclophosphamide 74
                5-fluorouracil 1465
                IC202A 0
                IC202B 0
                IC202C 0
                ascomycin 2
                auranofin 50
                azaserine 0
                azathioprine 638
                baricitinib 9
                betamethasone + 25
                betamethasone phosphate 0
                brasilicardin A 0
                brasilinolide A 0
                brazilein 6
                brequinar 1
                brequinar sodium 0
                chetomin 4
                chlorambucil 52
                cimifoetiside A 0
                cimifoetiside B 0
                cladribine 22
                cyclophosphamide + 760
                cyclophosphamide hydrate 0
                cyclosporin A + 8359
                cytarabine 583
                demethylzeylasteral 0
                dexamethasone + 4578
                dexrazoxane hydrochloride 0
                dimethyl sulfate 5
                etrasimod 0
                etrasimod arginine 0
                everolimus 40
                fentin chloride 108
                fingolimod + 0
                fingolimod hydrochloride 71
                fingolimod phosphate 0
                fludarabine phosphate 0
                flunisolide 8
                gemcitabine + 283
                gemcitabine hydrochloride 0
                ginsenoside Rd + 45
                gliotoxin 29
                hydrocortamate + 0
                ifosfamide 248
                leflunomide 2623
                lymphostin 0
                melphalan 275
                methotrexate 2411
                mycophenolate mofetil 1
                mycophenolate sodium 0
                mycophenolic acid + 112
                myriocin 12
                neosartoricin 0
                pachyaximine A 0
                phenanthridone 20
                physalin F 0
                prednisolone + 241
                prednisone + 38
                psora 4 0
                ritlecitinib 0
                ritlecitinib tosylate 0
                scoparone 35
                sirolimus + 524
                sotrastaurin 4
                spermine + 69
                stevastelin B 0
                stevastelin B3 0
                tacrolimus (anhydrous) + 434
                tacrolimus hydrate 431
                thalidomide + 467
                thiamphenicol 1
                triptonide 5710
                undecylprodigiosin 0
                vamorolone 0
                vincaleukoblastine + 1333
                wilformine 0
                zilucoplan 0
                zilucoplan sodium 0
    Path 2
    Term Annotations click to browse term
      CHEBI ontology 19808
        role 19784
          application 19627
            pharmaceutical 19468
              drug 19468
                immunomodulator 15051
                  immunosuppressive agent 13923
                    (+)-dexrazoxane + 176
                    4'-demethyldeoxypodophyllotoxin 0
                    4-hydroperoxycyclophosphamide 74
                    5-fluorouracil 1465
                    IC202A 0
                    IC202B 0
                    IC202C 0
                    ascomycin 2
                    auranofin 50
                    azaserine 0
                    azathioprine 638
                    baricitinib 9
                    betamethasone + 25
                    betamethasone phosphate 0
                    brasilicardin A 0
                    brasilinolide A 0
                    brazilein 6
                    brequinar 1
                    brequinar sodium 0
                    chetomin 4
                    chlorambucil 52
                    cimifoetiside A 0
                    cimifoetiside B 0
                    cladribine 22
                    cyclophosphamide + 760
                    cyclophosphamide hydrate 0
                    cyclosporin A + 8359
                    cytarabine 583
                    demethylzeylasteral 0
                    dexamethasone + 4578
                    dexrazoxane hydrochloride 0
                    dimethyl sulfate 5
                    etrasimod 0
                    etrasimod arginine 0
                    everolimus 40
                    fentin chloride 108
                    fingolimod + 0
                    fingolimod hydrochloride 71
                    fingolimod phosphate 0
                    fludarabine phosphate 0
                    flunisolide 8
                    gemcitabine + 283
                    gemcitabine hydrochloride 0
                    ginsenoside Rd + 45
                    gliotoxin 29
                    hydrocortamate + 0
                    ifosfamide 248
                    leflunomide 2623
                    lymphostin 0
                    melphalan 275
                    methotrexate 2411
                    mycophenolate mofetil 1
                    mycophenolate sodium 0
                    mycophenolic acid + 112
                    myriocin 12
                    neosartoricin 0
                    pachyaximine A 0
                    phenanthridone 20
                    physalin F 0
                    prednisolone + 241
                    prednisone + 38
                    psora 4 0
                    ritlecitinib 0
                    ritlecitinib tosylate 0
                    scoparone 35
                    sirolimus + 524
                    sotrastaurin 4
                    spermine + 69
                    stevastelin B 0
                    stevastelin B3 0
                    tacrolimus (anhydrous) + 434
                    tacrolimus hydrate 431
                    thalidomide + 467
                    thiamphenicol 1
                    triptonide 5710
                    undecylprodigiosin 0
                    vamorolone 0
                    vincaleukoblastine + 1333
                    wilformine 0
                    zilucoplan 0
                    zilucoplan sodium 0
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