ONTOLOGY REPORT - ANNOTATIONS

Term:azathioprine
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Accession:CHEBI:2948 term browser browse the term
Definition:A thiopurine that has formula C9H7N7O2S.
Synonyms:exact_synonym: 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine
 related_synonym: 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine;   6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine;   C9H7N7O2S;   Cn1cnc(c1Sc1ncnc2nc[nH]c12)[N+]([O-])=O;   Imuran (TN);   InChI=1S/C9H7N7O2S/c1-15-4-14-7(16(17)18)9(15)19-8-5-6(11-2-10-5)12-3-13-8/h2-4H,1H3,(H,10,11,12,13);   InChIKey=LMEKQMALGUDUQG-UHFFFAOYSA-N
 xref_casrn: 446-86-6
 xref: ChEMBL:531141 "ChEMBL COMPOUND";   ChemIDplus:446-86-6 "CAS Registry Number";   DrugBank:DB00993 "DrugBank";   KEGG DRUG:446-86-6 "CAS Registry Number";   KEGG DRUG:D00238 "KEGG DRUG"
 xref_mesh: MESH:D001379
 xref: Wikipedia:Azathioprine "Wikipedia"

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azathioprine term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link affects response to substance ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Alb albumin GBrowse link multiple interactions EXP 14 19,126,935 19,142,214 RGD:6480464 CTD
G Bcl2l1 Bcl2-like 1 GBrowse link decreases expression ISO 3 143,129,087 143,180,199 RGD:6480464 CTD
G Dpp4 dipeptidylpeptidase 4 GBrowse link decreases expression ISO 3 44,279,255 44,360,283 RGD:6480464 CTD
G Fam19a5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5 GBrowse link decreases expression ISO 7 125,835,416 126,056,345 RGD:6480464 CTD
G Fmo2 flavin containing monooxygenase 2 GBrowse link increases expression ISO 13 78,546,315 78,592,870 RGD:6480464 CTD
G Gclm glutamate cysteine ligase, modifier subunit GBrowse link increases expression ISO 2 218,895,434 218,915,491 RGD:6480464 CTD
G Gpx2 glutathione peroxidase 2 GBrowse link increases expression ISO 6 99,372,418 99,376,230 RGD:6480464 CTD
G Gpx3 glutathione peroxidase 3 GBrowse link increases expression ISO 10 40,311,094 40,319,382 RGD:6480464 CTD
G Gss glutathione synthetase GBrowse link increases expression ISO 3 146,057,517 146,087,820 RGD:6480464 CTD
G Gsta1 glutathione S-transferase alpha 1 GBrowse link affects metabolic processing ISO 9 20,051,501 20,068,146 RGD:6480464 CTD
G Gsta2 glutathione S-transferase alpha 2 GBrowse link affects metabolic processing ISO 8 83,299,249 83,312,958 RGD:6480464 CTD
G Gsta2 glutathione S-transferase alpha 2 GBrowse link affects metabolic processing ISO 8 83,299,249 83,312,958 RGD:6480464 CTD
G Gsta2 glutathione S-transferase alpha 2 GBrowse link affects response to substance ISO 8 83,299,249 83,312,958 RGD:6480464 CTD
G Gstm1 glutathione S-transferase mu 1 GBrowse link affects response to substance ISO 2 203,575,444 203,580,821 RGD:6480464 CTD
G Gstm1 glutathione S-transferase mu 1 GBrowse link affects metabolic processing ISO 2 203,575,444 203,580,821 RGD:6480464 CTD
G Gstm1 glutathione S-transferase mu 1 GBrowse link affects metabolic processing ISO 2 203,575,444 203,580,821 RGD:6480464 CTD
G Hp haptoglobin GBrowse link multiple interactions EXP 19 39,443,016 39,447,566 RGD:6480464 CTD
G Hprt1 hypoxanthine phosphoribosyltransferase 1 GBrowse link increases mutagenesis ISO X 139,929,647 139,961,616 RGD:6480464 CTD
G Ifnb1 interferon beta 1, fibroblast GBrowse link decreases expression ISO 5 107,837,628 107,838,182 RGD:6480464 CTD
G Il12a interleukin 12A GBrowse link multiple interactions ISO 2 158,710,261 158,717,689 RGD:6480464 CTD
G Il12b interleukin 12B GBrowse link multiple interactions ISO 10 29,558,955 29,568,331 RGD:6480464 CTD
G Il1a interleukin 1 alpha GBrowse link multiple interactions ISO 3 116,913,612 116,924,114 RGD:6480464 CTD
G Il4 interleukin 4 GBrowse link decreases expression ISO 10 39,074,582 39,080,134 RGD:6480464 CTD
G Il6 interleukin 6 GBrowse link multiple interactions ISO 4 456,799 461,376 RGD:6480464 CTD
G Impdh1 IMP (inosine 5'-monophosphate) dehydrogenase 1 GBrowse link affects response to substance ISO 4 56,075,236 56,090,775 RGD:6480464 CTD
G Impdh2 IMP (inosine 5'-monophosphate) dehydrogenase 2 GBrowse link increases expression ISO 8 113,607,025 113,611,613 RGD:6480464 CTD
G Irf1 interferon regulatory factor 1 GBrowse link decreases expression ISO 10 39,220,600 39,227,602 RGD:6480464 CTD
G Itpa inosine triphosphatase (nucleoside triphosphate pyrophosphatase) GBrowse link affects response to substance ISO 3 118,298,330 118,310,110 RGD:6480464 CTD
G Itpa inosine triphosphatase (nucleoside triphosphate pyrophosphatase) GBrowse link affects response to substance ISO 3 118,298,330 118,310,110 RGD:6480464 CTD
G Itpa inosine triphosphatase (nucleoside triphosphate pyrophosphatase) GBrowse link affects response to substance ISO 3 118,298,330 118,310,110 RGD:6480464 CTD
G Itpa inosine triphosphatase (nucleoside triphosphate pyrophosphatase) GBrowse link affects response to substance ISO 3 118,298,330 118,310,110 RGD:6480464 CTD
G Itpa inosine triphosphatase (nucleoside triphosphate pyrophosphatase) GBrowse link affects response to substance ISO 3 118,298,330 118,310,110 RGD:6480464 CTD
G Itpa inosine triphosphatase (nucleoside triphosphate pyrophosphatase) GBrowse link affects response to substance ISO 3 118,298,330 118,310,110 RGD:6480464 CTD
G Itpa inosine triphosphatase (nucleoside triphosphate pyrophosphatase) GBrowse link affects response to substance ISO 3 118,298,330 118,310,110 RGD:6480464 CTD
G Keap1 Kelch-like ECH-associated protein 1 GBrowse link affects response to substance ISO 8 20,259,178 20,266,351 RGD:6480464 CTD
G Lias lipoic acid synthetase GBrowse link increases expression ISO 14 45,575,334 45,592,514 RGD:6480464 CTD
G Ltf lactotransferrin GBrowse link decreases expression ISO 8 115,417,764 115,440,609 RGD:6480464 CTD
G Map2k1 mitogen activated protein kinase kinase 1 GBrowse link decreases phosphorylation ISO 8 68,379,074 68,451,554 RGD:6480464 CTD
G Msh2 mutS homolog 2 (E. coli) GBrowse link affects response to substance ISO 6 11,199,906 11,258,350 RGD:6480464 CTD
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 GBrowse link multiple interactions ISO 3 58,366,693 58,394,116 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link decreases expression ISO 10 65,036,884 65,072,453 RGD:6480464 CTD
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link increases activity ISO 19 37,251,147 37,266,040 RGD:6480464 CTD
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link multiple interactions ISO 19 37,251,147 37,266,040 RGD:6480464 CTD
G Orm1 orosomucoid 1 GBrowse link multiple interactions EXP 5 80,325,042 80,328,194 RGD:6480464 CTD
G Piga phosphatidylinositol glycan anchor biosynthesis, class A GBrowse link affects mutagenesis EXP X 50,797,413 50,812,217 RGD:6480464 CTD
G Ptch1 patched 1 GBrowse link affects mutagenesis ISO 17 7,088,234 7,142,459 RGD:6480464 CTD
G Rac1 ras-related C3 botulinum toxin substrate 1 GBrowse link multiple interactions ISO 12 11,380,314 11,400,531 RGD:6480464 CTD
G Rac1 ras-related C3 botulinum toxin substrate 1 GBrowse link decreases activity ISO 12 11,380,314 11,400,531 RGD:6480464 CTD
G Rac1 ras-related C3 botulinum toxin substrate 1 GBrowse link affects binding ISO 12 11,380,314 11,400,531 RGD:6480464 CTD
G Rac1 ras-related C3 botulinum toxin substrate 1 GBrowse link affects response to substance ISO 12 11,380,314 11,400,531 RGD:6480464 CTD
G Serinc3 serine incorporator 3 GBrowse link increases expression ISO 3 154,539,792 154,559,239 RGD:6480464 CTD
G Serpina1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 GBrowse link multiple interactions EXP 6 127,998,617 128,021,719 RGD:6480464 CTD
G Slc15a1 solute carrier family 15 (oligopeptide transporter), member 1 GBrowse link decreases expression ISO 15 106,549,586 106,592,594 RGD:6480464 CTD
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link increases expression ISO 1 41,862,997 41,870,327 RGD:6480464 CTD
G Stat3 signal transducer and activator of transcription 3 (acute-phase response factor) GBrowse link multiple interactions ISO 10 89,821,078 89,872,970 RGD:6480464 CTD
G Tex261 testis expressed 261 GBrowse link increases expression ISO 4 117,963,579 117,968,532 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link increases expression ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases expression ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases mutagenesis ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tpmt thiopurine S-methyltransferase GBrowse link affects response to substance ISO 17 23,697,900 23,714,173 RGD:6480464 CTD
G Tpmt thiopurine S-methyltransferase GBrowse link affects response to substance ISO 17 23,697,900 23,714,173 RGD:6480464 CTD
G Tpmt thiopurine S-methyltransferase GBrowse link affects response to substance ISO 17 23,697,900 23,714,173 RGD:6480464 CTD
G Tpmt thiopurine S-methyltransferase GBrowse link affects response to substance ISO 17 23,697,900 23,714,173 RGD:6480464 CTD
G Tpmt thiopurine S-methyltransferase GBrowse link affects activity ISO 17 23,697,900 23,714,173 RGD:6480464 CTD
G Tpmt thiopurine S-methyltransferase GBrowse link affects response to substance ISO 17 23,697,900 23,714,173 RGD:6480464 CTD
G Tpmt thiopurine S-methyltransferase GBrowse link affects response to substance ISO 17 23,697,900 23,714,173 RGD:6480464 CTD
G Tpmt thiopurine S-methyltransferase GBrowse link affects response to substance ISO 17 23,697,900 23,714,173 RGD:6480464 CTD
G Tpmt thiopurine S-methyltransferase GBrowse link affects response to substance ISO 17 23,697,900 23,714,173 RGD:6480464 CTD
G Tpmt thiopurine S-methyltransferase GBrowse link affects metabolic processing ISO 17 23,697,900 23,714,173 RGD:6480464 CTD
G Tpmt thiopurine S-methyltransferase GBrowse link affects response to substance ISO 17 23,697,900 23,714,173 RGD:6480464 CTD
G Tpmt thiopurine S-methyltransferase GBrowse link affects response to substance ISO 17 23,697,900 23,714,173 RGD:6480464 CTD
G Tpmt thiopurine S-methyltransferase GBrowse link affects response to substance ISO 17 23,697,900 23,714,173 RGD:6480464 CTD
G Vav1 vav 1 guanine nucleotide exchange factor increases expression ISO RGD:6480464 CTD
Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 492574
    role 482262
      biological role 480454
        biochemical role 193861
          antimetabolite 6424
            azathioprine 75
Path 2
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  CHEBI ontology 492574
    subatomic particle 491537
      composite particle 491537
        hadron 491537
          baryon 491537
            nucleon 491537
              atomic nucleus 491537
                atom 491537
                  main group element atom 461203
                    p-block element atom 458699
                      carbon group element atom 410677
                        carbon atom 407233
                          organic molecular entity 407226
                            organic molecule 359465
                              organic cyclic compound 298342
                                organic heterocyclic compound 154273
                                  organic heteromonocyclic compound 58845
                                    mancude organic heteromonocyclic parent 8900
                                      azole 7417
                                        diazole 3604
                                          imidazoles 2794
                                            azathioprine 75
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