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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Acetyl tributyl citrate
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Accession:CHEBI:168067 term browser browse the term
Synonyms:exact_synonym: tributyl 2-acetyloxypropane-1,2,3-tricarboxylate
 related_synonym: Formula=C20H34O8;   InChI=1S/C20H34O8/c1-5-8-11-25-17(22)14-20(28-16(4)21,19(24)27-13-10-7-3)15-18(23)26-12-9-6-2/h5-15H2,1-4H3;   InChIKey=QZCLKYGREBVARF-UHFFFAOYSA-N;   SMILES=O(C(CC(OCCCC)=O)(CC(OCCCC)=O)C(OCCCC)=O)C(=O)C
 xref: CAS:77-90-7;   Chemspider:6259;   HMDB:HMDB0034159
 xref_mesh: MESH:C014953


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Acetyl tributyl citrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha increases expression
multiple interactions		 ISO 2-acetyltributylcitrate results in increased expression of ACACA mRNA; 2-acetyltributylcitrate results in increased expression of ACACA protein
[2-acetyltributylcitrate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ACACA mRNA		 CTD PMID:37055963 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acacb acetyl-CoA carboxylase beta increases expression ISO 2-acetyltributylcitrate results in increased expression of ACACB mRNA CTD PMID:37055963 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655 		JBrowse link
G Acot1 acyl-CoA thioesterase 1 increases expression ISO 2-acetyltributylcitrate results in increased expression of ACOT1 mRNA CTD PMID:37055963 NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163 		JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression ISO 2-acetyltributylcitrate results in increased expression of ACOT2 mRNA CTD PMID:37055963 NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245 		JBrowse link
G Acot3 acyl-CoA thioesterase 3 increases expression ISO 2-acetyltributylcitrate results in increased expression of ACOT3 mRNA CTD PMID:37055963 NCBI chr 6:103,682,518...103,688,735
Ensembl chr 6:103,682,596...103,688,427
Ensembl chr 6:103,682,596...103,688,427 		JBrowse link
G Acot4 acyl-CoA thioesterase 4 increases expression ISO 2-acetyltributylcitrate results in increased expression of ACOT4 mRNA CTD PMID:37055963 NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917 		JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 increases expression ISO 2-acetyltributylcitrate results in increased expression of ALDH3A2 mRNA CTD PMID:37055963 NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281 		JBrowse link
G Cd36 CD36 molecule increases expression
multiple interactions		 ISO 2-acetyltributylcitrate results in increased expression of CD36 mRNA; 2-acetyltributylcitrate results in increased expression of CD36 protein
[2-acetyltributylcitrate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 mRNA		 CTD PMID:37055963 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 increases expression ISO 2-acetyltributylcitrate results in increased expression of CYP11A1 mRNA CTD PMID:28235592 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 increases expression ISO 2-acetyltributylcitrate results in increased expression of CYP11B2 mRNA CTD PMID:28235592 NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression
increases expression		 ISO 2-acetyltributylcitrate results in decreased expression of CYP17A1 mRNA
2-acetyltributylcitrate results in increased expression of CYP17A1 mRNA		 CTD PMID:28235592 PMID:37055963 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases expression ISO 2-acetyltributylcitrate results in decreased expression of CYP1A2 mRNA CTD PMID:37055963 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 decreases expression ISO 2-acetyltributylcitrate results in decreased expression of CYP2C55 mRNA CTD PMID:37055963 NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases expression
increases activity		 ISO 2-acetyltributylcitrate promotes the reaction [Calcitriol results in increased expression of CYP3A4 mRNA]; 2-acetyltributylcitrate promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]; Calcitriol promotes the reaction [2-acetyltributylcitrate results in increased activity of CYP3A4 protein]; Calcitriol promotes the reaction [2-acetyltributylcitrate results in increased expression of CYP3A4 mRNA]; NR1I2 protein affects the reaction [2-acetyltributylcitrate results in increased expression of CYP3A4 mRNA] CTD PMID:21742782 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP 2-acetyltributylcitrate results in increased expression of CYP3A23-3A1 mRNA CTD PMID:21742782 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Cyp51 cytochrome P450, family 51 decreases expression ISO 2-acetyltributylcitrate results in decreased expression of CYP51 mRNA CTD PMID:37055963 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410 		JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 decreases expression ISO 2-acetyltributylcitrate results in decreased expression of CYP7B1 mRNA CTD PMID:37055963 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase decreases expression ISO 2-acetyltributylcitrate results in decreased expression of DHCR7 mRNA CTD PMID:37055963 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055 		JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression ISO 2-acetyltributylcitrate results in increased expression of EHHADH mRNA CTD PMID:37055963 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188 		JBrowse link
G Elovl7 ELOVL fatty acid elongase 7 decreases expression ISO 2-acetyltributylcitrate results in decreased expression of ELOVL7 mRNA CTD PMID:37055963 NCBI chr 2:39,789,229...39,858,579
Ensembl chr 2:39,789,250...39,856,845 		JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions
increases expression		 ISO [2-acetyltributylcitrate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FABP4 mRNA
2-acetyltributylcitrate results in increased expression of FABP4 mRNA		 CTD PMID:37055963 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578 		JBrowse link
G Fasn fatty acid synthase decreases expression ISO 2-acetyltributylcitrate results in decreased expression of FASN mRNA CTD PMID:37055963 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Gal3st1 galactose-3-O-sulfotransferase 1 increases expression ISO 2-acetyltributylcitrate results in increased expression of GAL3ST1 mRNA CTD PMID:37055963 NCBI chr14:78,868,049...78,886,402
Ensembl chr14:78,870,793...78,886,388 		JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO 2-acetyltributylcitrate results in increased expression of GPAT3 mRNA CTD PMID:37055963 NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490 		JBrowse link
G Gpcpd1 glycerophosphocholine phosphodiesterase 1 increases expression ISO 2-acetyltributylcitrate results in increased expression of GPCPD1 mRNA CTD PMID:37055963 NCBI chr 3:119,787,681...119,832,550
Ensembl chr 3:119,787,682...119,832,517 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression ISO 2-acetyltributylcitrate results in decreased expression of HMGCS1 mRNA CTD PMID:37055963 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 increases expression ISO 2-acetyltributylcitrate results in increased expression of HSD3B2 mRNA CTD PMID:28235592 NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852 		JBrowse link
G Lipg lipase G, endothelial type increases expression ISO 2-acetyltributylcitrate results in increased expression of LIPG mRNA CTD PMID:37055963 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260 		JBrowse link
G Lss lanosterol synthase decreases expression ISO 2-acetyltributylcitrate results in decreased expression of LSS mRNA CTD PMID:37055963 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762 		JBrowse link
G Msmo1 methylsterol monooxygenase 1 decreases expression ISO 2-acetyltributylcitrate results in decreased expression of MSMO1 mRNA CTD PMID:37055963 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016 		JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO 2-acetyltributylcitrate promotes the reaction [NCOA1 protein binds to NR1I2 protein] CTD PMID:21742782 NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664 		JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO 2-acetyltributylcitrate promotes the reaction [NCOA2 protein binds to NR1I2 protein] CTD PMID:21742782 NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions		 ISO
EXP		 2-acetyltributylcitrate results in increased activity of NR1I2 protein
2-acetyltributylcitrate promotes the reaction [NCOA1 protein binds to NR1I2 protein]; 2-acetyltributylcitrate promotes the reaction [NCOA2 protein binds to NR1I2 protein]; 2-acetyltributylcitrate promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]; NR1I2 protein affects the reaction [2-acetyltributylcitrate results in increased expression of CYP3A4 mRNA]		 CTD PMID:21742782 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like decreases expression ISO 2-acetyltributylcitrate results in decreased expression of NSDHL mRNA CTD PMID:37055963 NCBI chr  X:150,775,034...150,807,161
Ensembl chr  X:150,775,080...150,807,142 		JBrowse link
G Ptgds prostaglandin D2 synthase decreases expression ISO 2-acetyltributylcitrate results in decreased expression of PTGDS mRNA CTD PMID:37055963 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833 		JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions
increases expression		 ISO [2-acetyltributylcitrate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SCD1 mRNA
2-acetyltributylcitrate results in increased expression of SCD1 mRNA; 2-acetyltributylcitrate results in increased expression of SCD1 protein		 CTD PMID:37055963 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Sqle squalene epoxidase decreases expression ISO 2-acetyltributylcitrate results in decreased expression of SQLE mRNA CTD PMID:37055963 NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases cleavage
decreases expression		 ISO 2-acetyltributylcitrate results in decreased cleavage of SREBF1 protein
2-acetyltributylcitrate results in decreased expression of SREBF1 mRNA		 CTD PMID:37055963 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19844
    chemical entity 19842
      atom 19842
        nonmetal atom 19780
          oxygen atom 19491
            oxygen molecular entity 19523
              organooxygen compound 19167
                Acetyl tributyl citrate 38
Path 2
Term Annotations click to browse term
  CHEBI ontology 19844
    subatomic particle 19842
      composite particle 19842
        hadron 19842
          baryon 19842
            nucleon 19809
              atomic nucleus 19842
                atom 19842
                  main group element atom 19792
                    p-block element atom 19792
                      carbon group element atom 19738
                        carbon atom 19734
                          organic molecular entity 19734
                            heteroorganic entity 19486
                              organochalcogen compound 19249
                                organooxygen compound 19167
                                  carbon oxoacid 18634
                                    carboxylic acid 18631
                                      tetracarboxylic acid 541
                                        Acetyl tributyl citrate 38
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