Gene: Cyp7b1 (cytochrome P450 family 7 subfamily B member 1) Rattus norvegicus
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Symbol: Cyp7b1
Name: cytochrome P450 family 7 subfamily B member 1
Description: ENCODES a protein that exhibits oxysterol 7-alpha-hydroxylase activity (ortholog); INVOLVED IN circadian rhythm; memory; response to cAMP; PARTICIPATES IN bile acid biosynthetic pathway; cerebrotendinous xanthomatosis disease pathway; congenital bile acid synthesis defect pathway; ASSOCIATED WITH Adenocarcinoma (ortholog); adenocarcinoma (ortholog); adrenal cortical adenocarcinoma (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); integral component of membrane (inferred); organelle membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3',5'-cyclic AMP; ammonium chloride
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 25-hydroxycholesterol 7-alpha-hydroxylase; Cytochrom P450; cytochrome P450 7B1; cytochrome P450, family 7, subfamily b, polypeptide 1; cytochrome P450, subfamily 7B, polypeptide 1; HCT-1; hippocampal transcript 1 protein; oxysterol 7-alpha-hydroxylase
Orthologs:
Homo sapiens (human) : CYP7B1 (cytochrome P450 family 7 subfamily B member 1)  HGNC
Mus musculus (house mouse) : Cyp7b1 (cytochrome P450, family 7, subfamily b, polypeptide 1)  MGI
Chinchilla lanigera (long-tailed chinchilla) : LOC102022645 (25-hydroxycholesterol 7-alpha-hydroxylase)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100995737 (25-hydroxycholesterol 7-alpha-hydroxylase)
Canis lupus familiaris (dog) : CYP7B1 (cytochrome P450, family 7, subfamily B, polypeptide 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101955077 (25-hydroxycholesterol 7-alpha-hydroxylase)
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Allele / Splice: Cyp7b1Tn(sb-T2/Bart3)2.306Mcwi  
Genetic Models: F344-Cyp7b1Tn(sb-T2/Bart3)2.306Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: spans an assembly gap
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02102,701,903 - 102,871,257 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.02122,442,002 - 122,610,354 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.42103,102,679 - 103,271,273 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12103,048,320 - 103,073,714 (-)NCBI
Celera295,908,860 - 96,075,269 (-)NCBI
Cytogenetic Map2q24NCBImapview
RH 3.4 Map2606.1RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
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RGD Object Information
RGD ID: 2483
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-09-05
Status: ACTIVE