Gene: Cyp7b1 (cytochrome P450, family 7, subfamily b, polypeptide 1) Rattus norvegicus
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Symbol: Cyp7b1
Name: cytochrome P450, family 7, subfamily b, polypeptide 1
Description: ENCODES a protein that exhibits oxysterol 7-alpha-hydroxylase activity (ortholog); INVOLVED IN circadian rhythm; memory; response to cAMP; PARTICIPATES IN bile acid biosynthetic pathway; cerebrotendinous xanthomatosis disease pathway; congenital bile acid synthesis defect pathway; ASSOCIATED WITH Adenocarcinoma (ortholog); Bile Acid Synthesis Defect, Congenital, 3 (ortholog); Cholestasis (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); integral component of membrane (inferred); organelle membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3',5'-cyclic AMP; ammonium chloride
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 25-hydroxycholesterol 7-alpha-hydroxylase; Cytochrom P450; cytochrome P450 7B1; cytochrome P450, subfamily 7B, polypeptide 1; HCT-1; hippocampal transcript 1 protein; oxysterol 7-alpha-hydroxylase
Orthologs:
Allele / Splice: Cyp7b1Tn(sb-T2/Bart3)2.306Mcwi  
Genetic Models: F344-Cyp7b1Tn(sb-T2/Bart3)2.306Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: spans an assembly gap
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02102,701,903 - 102,871,257 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.02122,442,002 - 122,610,354 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.42103,102,679 - 103,271,273 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12103,048,320 - 103,073,714 (-)NCBI
Celera295,908,860 - 96,075,269 (-)NCBI
Cytogenetic Map2q24NCBImapview
RH 3.4 Map2606.1RGD
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cyp7b1
NCBI Gene
Ensembl Gene
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RGD Object Information
RGD ID: 2483
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-11-22
Status: ACTIVE