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ONTOLOGY REPORT - ANNOTATIONS

Term:Toll signaling pathway
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Accession:GO:0008063 term browser browse the term
Definition:The series of molecular signals initiated by an extracellular ligand binding to the receptor Toll on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: Tl signaling pathway;   Tl signalling pathway;   Toll signalling pathway


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Toll signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irak1 interleukin-1 receptor-associated kinase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:156,919,927...156,929,825
Ensembl chr  X:156,920,081...156,929,825 		JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:148,341,704...148,398,211
Ensembl chr 4:148,341,719...148,398,210 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:57,538,522...57,600,166
Ensembl chr 7:57,539,557...57,598,706 		JBrowse link
G Irak4 interleukin-1 receptor-associated kinase 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:127,561,777...127,588,762
Ensembl chr 7:127,561,717...127,597,109 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor involved_in IDA
IBA 		GO_REF:0000033 GO_Central
RGD		 PMID:14962484 GO_REF:0000033, RGD:1302746 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:127,952,161...127,956,230 		JBrowse link
G Palm3 paralemmin 3 involved_in ISO
IBA 		(PMID:21187075)
GO_REF:0000033 		RGD
GO_Central		 PMID:21187075 GO_REF:0000033 NCBI chr19:41,026,757...41,035,217
Ensembl chr19:41,026,518...41,035,293 		JBrowse link
G Traf3 Tnf receptor-associated factor 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:136,025,097...136,128,363
Ensembl chr 6:136,027,157...136,128,363 		JBrowse link
negative regulation of Toll signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano9 anoctamin 9 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 1:205,638,571...205,659,780
Ensembl chr 1:205,638,572...205,659,489 		JBrowse link
G Nlrp12 NLR family, pyrin domain containing 12 involved_in ISO (PMID:16203735) RGD PMID:16203735 NCBI chr 1:74,848,020...74,885,945
Ensembl chr 1:74,848,063...74,876,341 		JBrowse link
G Peli3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO MGI:2156367 (PMID:23042151) RGD PMID:23042151 NCBI chr 1:211,659,416...211,672,280
Ensembl chr 1:211,661,610...211,672,239 		JBrowse link
G Sigirr single Ig and TIR domain containing involved_in ISO
ISS 		(PMID:12925853)
GO_REF:0000024 		RGD
HGNC-UCL		 PMID:12925853 GO_REF:0000024 NCBI chr 1:205,625,742...205,637,883
Ensembl chr 1:205,627,708...205,637,802 		JBrowse link
positive regulation of Toll signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO UniProtKB:O00206|UniProtKB:P16671|UniProtKB:Q9Y2C9 (PMID:20037584) RGD PMID:20037584 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971 		JBrowse link
regulation of Toll signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Peli1 pellino E3 ubiquitin protein ligase 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr14:99,455,970...99,510,474
Ensembl chr14:99,455,811...99,510,466 		JBrowse link
G Peli2 pellino E3 ubiquitin protein ligase family member 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr15:23,872,984...24,017,448
Ensembl chr15:23,872,984...24,014,817 		JBrowse link
G Peli3 pellino E3 ubiquitin protein ligase family member 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:211,659,416...211,672,280
Ensembl chr 1:211,661,610...211,672,239 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19665
    cellular process 18832
      signal transduction 7243
        cell surface receptor signaling pathway 2949
          Toll signaling pathway 14
            negative regulation of Toll signaling pathway 4
            positive regulation of Toll signaling pathway 1
            regulation of Toll signaling pathway + 7
Path 2
Term Annotations click to browse term
  biological_process 19665
    biological regulation 13556
      regulation of biological process 13124
        signaling 7822
          signal transduction 7243
            cell surface receptor signaling pathway 2949
              Toll signaling pathway 14
                negative regulation of Toll signaling pathway 4
                positive regulation of Toll signaling pathway 1
                regulation of Toll signaling pathway + 7
paths to the root