Zfp729 (zinc finger protein 729) - Rat Genome Database

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Gene: Zfp729 (zinc finger protein 729) Rattus norvegicus
Analyze
Symbol: Zfp729 (Ensembl: LOC102551340)
Name: zinc finger protein 729 (Ensembl:zinc finger protein 728-like)
RGD ID: 7697243
Description: Predicted to enable metal ion binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ZNF729 (zinc finger protein 729) and ZNF99 (zinc finger protein 99).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC100361619; LOC102551340; rCG42042-like; zinc finger protein 728-like
RGD Orthologs
Human
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8136,994,107 - 37,007,812 (-)NCBIGRCr8
mRatBN7.2135,165,732 - 35,183,894 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl135,165,722 - 35,183,884 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0138,525,850 - 38,543,402 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl138,527,519 - 38,538,987 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0139,896,569 - 39,914,341 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera133,735,274 - 33,807,264 (-)NCBICelera
Cytogenetic Map1p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA,IEA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Zfp729
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8136,994,107 - 37,007,812 (-)NCBIGRCr8
mRatBN7.2135,165,732 - 35,183,894 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl135,165,722 - 35,183,884 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0138,525,850 - 38,543,402 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl138,527,519 - 38,538,987 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0139,896,569 - 39,914,341 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera133,735,274 - 33,807,264 (-)NCBICelera
Cytogenetic Map1p11NCBI
ZNF729
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381922,286,441 - 22,317,176 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1922,286,441 - 22,317,176 (+)EnsemblGRCh38hg38GRCh38
GRCh371922,469,243 - 22,499,978 (+)NCBIGRCh37GRCh37hg19GRCh37
Celera1922,301,775 - 22,332,503 (+)NCBICelera
Cytogenetic Map19p12NCBI
HuRef1922,007,231 - 22,037,969 (+)NCBIHuRef
CHM1_11922,468,840 - 22,499,574 (+)NCBICHM1_1
T2T-CHM13v2.01922,425,067 - 22,455,810 (+)NCBIT2T-CHM13v2.0

Variants

.
Variants in Zfp729
40 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:12
Count of miRNA genes:12
Interacting mature miRNAs:12
Transcripts:ENSRNOT00000071275
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1165833076Rat
1578650Bmd6Bone mineral density QTL 612.2femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)150910843284926Rat
1578651Bmd7Bone mineral density QTL 714.2femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)150910843284926Rat
1578669Bss9Bone structure and strength QTL 96.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)150910843284926Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
1600360Mcs16Mammary carcinoma susceptibility QTL 162.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1224439043433040Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1439328949393289Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)1985600154856001Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11099206555992065Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11148131275088344Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)11183518156835181Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)11543162149361612Rat
5684999Bss102Bone structure and strength QTL 1025.50.00000072tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)11543162149361612Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)11620621049268520Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)11933357156983283Rat
1558642Prcr2Prostate cancer resistance QTL 24.3prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)12076315844095856Rat
724520Bp145Blood pressure QTL 1452.10.0024arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12078482865784828Rat
1357397Bw41Body weight QTL 414.190.0001body mass (VT:0001259)body weight (CMO:0000012)12234064749361612Rat
1357401Bw43Body weight QTL 433.75body mass (VT:0001259)body weight (CMO:0000012)12234064749361612Rat
1357400Bw62Body weight QTL624.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)12234064767340647Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)12887978078430678Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)13344984878449848Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)13344984878449848Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)13483685879836858Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 20 4 19 4 64 26 36 11
Low 2 43 37 37 37 8 10 10 9 5 8
Below cutoff 1

Sequence


RefSeq Acc Id: ENSRNOT00000071275   ⟹   ENSRNOP00000066288
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl135,165,722 - 35,183,884 (-)Ensembl
Rnor_6.0 Ensembl138,528,185 - 38,538,987 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000090406   ⟹   ENSRNOP00000071009
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl135,165,722 - 35,183,884 (-)Ensembl
Rnor_6.0 Ensembl138,527,519 - 38,538,987 (-)Ensembl
RefSeq Acc Id: XM_063276645   ⟹   XP_063132715
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8136,994,107 - 37,007,812 (-)NCBI
RefSeq Acc Id: XR_010058905
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8136,994,107 - 37,007,812 (-)NCBI
Protein Sequences
Protein RefSeqs XP_063132715 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000066288.3
  ENSRNOP00000071009.2
RefSeq Acc Id: ENSRNOP00000071009   ⟸   ENSRNOT00000090406
RefSeq Acc Id: ENSRNOP00000066288   ⟸   ENSRNOT00000071275
RefSeq Acc Id: XP_063132715   ⟸   XM_063276645
- UniProtKB: A0A0G2JZD8 (UniProtKB/TrEMBL)
Protein Domains
C2H2-type   KRAB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JZD8-F1-model_v2 AlphaFold A0A0G2JZD8 1-782 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:7697243 AgrOrtholog
BioCyc Gene G2FUF-61834 BioCyc
Ensembl Genes ENSRNOG00000047145 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000071275.3 UniProtKB/TrEMBL
  ENSRNOT00000090406.2 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro KRAB UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/TrEMBL
  Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_PHD UniProtKB/TrEMBL
NCBI Gene LOC102551340 ENTREZGENE
PANTHER REDUCED EXPRESSION 2-RELATED UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 200 UniProtKB/TrEMBL
Pfam KRAB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PhenoGen Zfp729 PhenoGen
PROSITE KRAB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000047145 RatGTEx
SMART KRAB UniProtKB/TrEMBL
  PHD UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF109640 UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A0G2JZD8 ENTREZGENE, UniProtKB/TrEMBL
  M0R9V7_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Zfp729  zinc finger protein 729  LOC102551340  zinc finger protein 728-like  Symbol and Name Changed 1299863 APPROVED
2015-07-29 LOC102551340  zinc finger protein 728-like  LOC100361619  rCG42042-like  Data merged from RGD:2319753 737654 PROVISIONAL
2013-12-18 LOC102551340  zinc finger protein 728-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2010-05-05 LOC100361619  rCG42042-like      Symbol and Name status set to provisional 70820 PROVISIONAL