Kcnh5 (potassium voltage-gated channel subfamily H member 5) - Rat Genome Database

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Gene: Kcnh5 (potassium voltage-gated channel subfamily H member 5) Rattus norvegicus
Analyze
Symbol: Kcnh5
Name: potassium voltage-gated channel subfamily H member 5
RGD ID: 621417
Description: Enables delayed rectifier potassium channel activity and transmembrane transporter binding activity. Involved in potassium ion transport. Predicted to be located in cell surface. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy. Orthologous to human KCNH5 (potassium voltage-gated channel subfamily H member 5); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Eag2; ether-a-go-go potassium channel 2; potassium channel, voltage gated eag related subfamily H, member 5; potassium voltage-gated channel, subfamily H (eag-related), member 5; rEAG2; voltage-gated delayed rectifier potassium channel KCNH5; voltage-gated potassium channel subunit Kv10.2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8699,350,947 - 99,643,856 (-)NCBIGRCr8
mRatBN7.2693,615,174 - 93,908,107 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl693,624,529 - 93,908,107 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx694,022,247 - 94,304,742 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0694,320,761 - 94,603,257 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0693,749,598 - 94,032,105 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0697,872,831 - 98,157,087 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl697,872,831 - 98,157,087 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06107,294,666 - 107,578,241 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4697,484,188 - 97,772,082 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1697,487,643 - 97,775,538 (-)NCBI
Celera692,059,360 - 92,339,391 (-)NCBICelera
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. The subfamily-specific assembly of Eag and Erg K+ channels is determined by both the amino and the carboxyl recognition domains. Lin TF, etal., J Biol Chem. 2014 Aug 15;289(33):22815-34. doi: 10.1074/jbc.M114.574814. Epub 2014 Jul 9.
3. Cloning and functional expression of rat eag2, a new member of the ether-a-go-go family of potassium channels and comparison of its distribution with that of eag1. Ludwig J, etal., Mol Cell Neurosci 2000 Jul;16(1):59-70.
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Cloning of components of a novel subthreshold-activating K(+) channel with a unique pattern of expression in the cerebral cortex. Saganich MJ, etal., J Neurosci 1999 Dec 15;19(24):10789-802.
9. Cloning of a mammalian elk potassium channel gene and EAG mRNA distribution in rat sympathetic ganglia. Shi W, etal., J Physiol 1998 Sep 15;511 ( Pt 3):675-82.
Additional References at PubMed
PMID:15706225   PMID:18063306   PMID:20662937   PMID:22855790   PMID:24495567   PMID:38797494  


Genomics

Comparative Map Data
Kcnh5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8699,350,947 - 99,643,856 (-)NCBIGRCr8
mRatBN7.2693,615,174 - 93,908,107 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl693,624,529 - 93,908,107 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx694,022,247 - 94,304,742 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0694,320,761 - 94,603,257 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0693,749,598 - 94,032,105 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0697,872,831 - 98,157,087 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl697,872,831 - 98,157,087 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06107,294,666 - 107,578,241 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4697,484,188 - 97,772,082 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1697,487,643 - 97,775,538 (-)NCBI
Celera692,059,360 - 92,339,391 (-)NCBICelera
Cytogenetic Map6q24NCBI
KCNH5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381462,699,464 - 63,045,458 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1462,699,464 - 63,102,037 (-)EnsemblGRCh38hg38GRCh38
GRCh371463,166,182 - 63,512,176 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361462,243,698 - 62,638,337 (-)NCBINCBI36Build 36hg18NCBI36
Build 341462,248,710 - 62,638,337NCBI
Celera1443,224,258 - 43,619,167 (-)NCBICelera
Cytogenetic Map14q23.2NCBI
HuRef1443,338,760 - 43,678,420 (-)NCBIHuRef
CHM1_11463,112,492 - 63,451,134 (-)NCBICHM1_1
T2T-CHM13v2.01456,906,444 - 57,253,090 (-)NCBIT2T-CHM13v2.0
Kcnh5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391274,943,991 - 75,224,625 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1274,943,994 - 75,224,106 (-)EnsemblGRCm39 Ensembl
GRCm381274,897,217 - 75,177,332 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1274,897,220 - 75,177,332 (-)EnsemblGRCm38mm10GRCm38
MGSCv371275,998,204 - 76,278,319 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361275,816,060 - 76,096,172 (-)NCBIMGSCv36mm8
Celera1275,988,289 - 76,268,710 (-)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1232.62NCBI
Kcnh5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554666,704,364 - 7,040,734 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554666,704,431 - 7,042,727 (+)NCBIChiLan1.0ChiLan1.0
KCNH5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21563,827,105 - 64,163,258 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11463,043,619 - 63,379,775 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01443,297,114 - 43,633,275 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11461,560,591 - 61,889,137 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1461,560,600 - 61,889,137 (-)Ensemblpanpan1.1panPan2
KCNH5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1837,429,677 - 37,710,409 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl837,434,922 - 37,710,330 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha837,191,479 - 37,467,676 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0837,663,234 - 37,937,001 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl837,666,227 - 37,936,864 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1837,271,557 - 37,554,004 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0837,357,200 - 37,633,582 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0837,713,171 - 37,986,803 (-)NCBIUU_Cfam_GSD_1.0
Kcnh5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864067,223,309 - 67,517,223 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364956,685,238 - 6,967,591 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364956,685,220 - 6,967,921 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNH5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1194,966,334 - 195,259,068 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11194,965,696 - 195,264,046 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
KCNH5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12439,856,837 - 40,206,607 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605328,091,424 - 28,430,148 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcnh5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473437,990,890 - 38,381,306 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473437,990,840 - 38,387,580 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Kcnh5
1536 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:190
Count of miRNA genes:123
Interacting mature miRNAs:137
Transcripts:ENSRNOT00000013275
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)689762877106752806Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)673463459109394713Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)682523650110548006Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)672202632117202632Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)683190345106747639Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)671201409116201409Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)661747639106747639Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)657730540104085867Rat
1300076Glom8Glomerulus QTL 879e-09kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat

Markers in Region
D6Mit8  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2693,701,310 - 93,701,509 (+)MAPPERmRatBN7.2
Rnor_6.0697,949,772 - 97,949,970NCBIRnor6.0
Rnor_5.06107,370,981 - 107,371,179UniSTSRnor5.0
RGSC_v3.4697,561,873 - 97,562,072RGDRGSC3.4
RGSC_v3.4697,561,874 - 97,562,072UniSTSRGSC3.4
RGSC_v3.1697,565,330 - 97,565,528RGD
Celera692,136,112 - 92,136,316UniSTS
RH 3.4 Map6656.3UniSTS
RH 3.4 Map6656.3RGD
RH 2.0 Map6861.5RGD
SHRSP x BN Map655.6199RGD
Cytogenetic Map6q24UniSTS
D6Arb20  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2693,641,596 - 93,641,736 (+)MAPPERmRatBN7.2
Rnor_6.0697,889,897 - 97,890,036NCBIRnor6.0
Rnor_5.06107,311,732 - 107,311,871UniSTSRnor5.0
RGSC_v3.4697,501,257 - 97,501,397RGDRGSC3.4
RGSC_v3.4697,501,258 - 97,501,397UniSTSRGSC3.4
RGSC_v3.1697,504,714 - 97,504,853RGD
Celera692,076,427 - 92,076,566UniSTS
RH 3.4 Map6657.3UniSTS
RH 3.4 Map6657.3RGD
RH 2.0 Map6859.3RGD
SHRSP x BN Map655.6199RGD
Cytogenetic Map6q24UniSTS
31.MMHAP7FLC4.seq  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2693,662,006 - 93,662,159 (+)MAPPERmRatBN7.2
Rnor_6.0697,910,305 - 97,910,457NCBIRnor6.0
Rnor_5.06107,332,140 - 107,332,292UniSTSRnor5.0
RGSC_v3.4697,521,666 - 97,521,818UniSTSRGSC3.4
Celera692,096,848 - 92,097,000UniSTS
Cytogenetic Map6q24UniSTS
WI-15244  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21201,580,885 - 201,580,992 (-)MAPPERmRatBN7.2
mRatBN7.2693,811,478 - 93,811,583 (+)MAPPERmRatBN7.2
Rnor_6.0698,061,305 - 98,061,409NCBIRnor6.0
Rnor_5.06107,482,459 - 107,482,563UniSTSRnor5.0
RGSC_v3.4697,675,459 - 97,675,563UniSTSRGSC3.4
Celera692,242,925 - 92,243,029UniSTS
Cytogenetic Map6q24UniSTS
Kcnh5  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2693,820,999 - 93,821,092 (+)MAPPERmRatBN7.2
Rnor_6.0698,070,824 - 98,070,916NCBIRnor6.0
Rnor_5.06107,491,978 - 107,492,070UniSTSRnor5.0
RGSC_v3.4697,684,985 - 97,685,077UniSTSRGSC3.4
Celera692,252,427 - 92,252,519UniSTS
Cytogenetic Map6q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 8 16 113 59 58 27 24 27 6 131 60 93 28 53 31

Sequence


Ensembl Acc Id: ENSRNOT00000013275   ⟹   ENSRNOP00000013275
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl693,624,529 - 93,908,107 (-)Ensembl
Rnor_6.0 Ensembl697,872,831 - 98,157,087 (-)Ensembl
RefSeq Acc Id: NM_133610   ⟹   NP_598294
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8699,360,302 - 99,643,856 (-)NCBI
mRatBN7.2693,624,529 - 93,908,107 (-)NCBI
Rnor_6.0697,872,831 - 98,157,087 (-)NCBI
Rnor_5.06107,294,666 - 107,578,241 (-)NCBI
RGSC_v3.4697,484,188 - 97,772,082 (-)RGD
Celera692,059,360 - 92,339,391 (-)RGD
Sequence:
RefSeq Acc Id: XM_039111744   ⟹   XP_038967672
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8699,350,947 - 99,583,967 (-)NCBI
mRatBN7.2693,615,174 - 93,848,207 (-)NCBI
RefSeq Acc Id: NP_598294   ⟸   NM_133610
- UniProtKB: O88893 (UniProtKB/Swiss-Prot),   Q9QXT2 (UniProtKB/Swiss-Prot),   Q9EPI9 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000013275   ⟸   ENSRNOT00000013275
RefSeq Acc Id: XP_038967672   ⟸   XM_039111744
- Peptide Label: isoform X1
- UniProtKB: A6HC74 (UniProtKB/TrEMBL)
Protein Domains
Cyclic nucleotide-binding   PAC   PAS

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9EPI9-F1-model_v2 AlphaFold Q9EPI9 1-988 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621417 AgrOrtholog
BioCyc Gene G2FUF-37084 BioCyc
Ensembl Genes ENSRNOG00000009542 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00055020005 UniProtKB/Swiss-Prot
  ENSRNOG00060028143 UniProtKB/Swiss-Prot
  ENSRNOG00065018672 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000013275.5 UniProtKB/Swiss-Prot
  ENSRNOT00055034161 UniProtKB/Swiss-Prot
  ENSRNOT00060048912 UniProtKB/Swiss-Prot
  ENSRNOT00065031354 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.1200.260 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.10.287.70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.120.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAS domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro cNMP-bd-like UniProtKB/Swiss-Prot
  cNMP-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  cNMP-bd_dom_sf UniProtKB/TrEMBL
  Ion_trans_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  K_chnl_dom UniProtKB/TrEMBL
  K_chnl_volt-dep_EAG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  K_chnl_volt-dep_EAG/ELK/ERG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KCNH_channel UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAS-assoc_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAS-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RmlC-like_jellyroll UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:171146 UniProtKB/Swiss-Prot
NCBI Gene 171146 ENTREZGENE
PANTHER POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 5 UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
  VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam cNMP_binding UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ion_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ion_trans_2 UniProtKB/TrEMBL
  PAS_9 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Kcnh5 PhenoGen
PRINTS EAGCHANLFMLY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EAGCHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CNMP_BINDING_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009542 RatGTEx
  ENSRNOG00055020005 RatGTEx
  ENSRNOG00060028143 RatGTEx
  ENSRNOG00065018672 RatGTEx
SMART cNMP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP cAMP-binding domain-like UniProtKB/TrEMBL
  PYP-like sensor domain (PAS domain) UniProtKB/TrEMBL
  SSF51206 UniProtKB/Swiss-Prot
  SSF55785 UniProtKB/Swiss-Prot
  Voltage-gated potassium channels UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6HC74 ENTREZGENE, UniProtKB/TrEMBL
  A6HC75_RAT UniProtKB/TrEMBL
  A6HC76_RAT UniProtKB/TrEMBL
  KCNH5_RAT UniProtKB/Swiss-Prot
  O88893 ENTREZGENE
  Q9EPI9 ENTREZGENE
  Q9QXT2 ENTREZGENE
UniProt Secondary O88893 UniProtKB/Swiss-Prot
  Q9QXT2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-11 Kcnh5  potassium voltage-gated channel subfamily H member 5  Kcnh5  potassium channel, voltage gated eag related subfamily H, member 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-01-26 Kcnh5  potassium channel, voltage gated eag related subfamily H, member 5  Kcnh5  potassium voltage-gated channel, subfamily H (eag-related), member 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Kcnh5  potassium voltage-gated channel, subfamily H (eag-related), member 5      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Kcnh5  potassium voltage-gated channel, subfamily H (eag-related), member 5      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference