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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17alpha-ethynylestradiol | affects expression | ISO | RGD:621417 | 6480464 | Ethinyl Estradiol affects the expression of KCNH5 mRNA | CTD | PMID:16079270 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:621417 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of KCNH5 mRNA | CTD | PMID:32109520 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | ISO | RGD:621417 | 6480464 | 2 more ... | CTD | PMID:32109520 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | RGD:1621304 | 6480464 | N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of KCNH5 mRNA | CTD | PMID:20188158 | 6-propyl-2-thiouracil | decreases expression | ISO | RGD:621417 | 6480464 | Propylthiouracil results in decreased expression of KCNH5 mRNA | CTD | PMID:24780913, PMID:25825206 | alendronic acid | affects expression | ISO | RGD:621417 | 6480464 | Alendronate affects the expression of KCNH5 mRNA | CTD | PMID:16079270 | all-trans-retinoic acid | decreases expression | EXP | | 6480464 | Tretinoin results in decreased expression of KCNH5 mRNA | CTD | PMID:21934132 | ammonium chloride | affects expression | ISO | RGD:621417 | 6480464 | Ammonium Chloride affects the expression of KCNH5 mRNA | CTD | PMID:16483693 | benzo[a]pyrene | multiple interactions | ISO | RGD:1621304 | 6480464 | Benzoapyrene promotes the reaction [AHR protein binds to KCNH5 promoter] | CTD | PMID:19654925 | benzo[a]pyrene | affects methylation | EXP | | 6480464 | Benzoapyrene affects the methylation of KCNH5 promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | ISO | RGD:1621304 | 6480464 | Benzoapyrene results in decreased methylation of KCNH5 intron | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | EXP | | 6480464 | Benzoapyrene results in increased methylation of KCNH5 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzoapyrene results in increased expression of KCNH5 mRNA | CTD | PMID:22316170 | bisphenol A | decreases expression | ISO | RGD:621417 | 6480464 | bisphenol A results in decreased expression of KCNH5 mRNA | CTD | PMID:25181051 | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-5-benzo1 more ... | CTD | PMID:27188386 | fenvalerate | increases expression | ISO | RGD:621417 | 6480464 | fenvalerate results in increased expression of KCNH5 mRNA | CTD | PMID:30307764 | indole-3-methanol | multiple interactions | ISO | RGD:621417 | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of KCNH5 mRNA | CTD | PMID:22129741 | N-acetyl-L-cysteine | multiple interactions | ISO | RGD:621417 | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of KCNH5 mRNA | CTD | PMID:22129741 | N-nitrosodiethylamine | multiple interactions | ISO | RGD:621417 | 6480464 | [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of KCNH5 mRNA, [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of KCNH5 mRNA | CTD | PMID:20360939, PMID:22129741 | O-methyleugenol | decreases expression | EXP | | 6480464 | methyleugenol results in decreased expression of KCNH5 mRNA | CTD | PMID:32234424 | panobinostat | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in decreased expression of KCNH5 mRNA | CTD | PMID:27188386 | panobinostat | decreases expression | EXP | | 6480464 | panobinostat results in decreased expression of KCNH5 mRNA | CTD | PMID:26272509 | paracetamol | affects expression | ISO | RGD:1621304 | 6480464 | Acetaminophen affects the expression of KCNH5 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of KCNH5 mRNA | CTD | PMID:26690555 | phenethyl caffeate | multiple interactions | ISO | RGD:621417 | 6480464 | [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of KCNH5 mRNA | CTD | PMID:20360939 | phenylmercury acetate | decreases expression | EXP | | 6480464 | Phenylmercuric Acetate results in decreased expression of KCNH5 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in decreased expression of KCNH5 mRNA | CTD | PMID:27188386 | potassium dichromate | decreases expression | ISO | RGD:1621304 | 6480464 | Potassium Dichromate results in decreased expression of KCNH5 mRNA | CTD | PMID:23608068 | raloxifene | affects expression | ISO | RGD:621417 | 6480464 | Raloxifene Hydrochloride affects the expression of KCNH5 mRNA | CTD | PMID:16079270 | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-5-benzo1 more ... | CTD | PMID:27188386 | sulforaphane | decreases expression | EXP | | 6480464 | sulforafan results in decreased expression of KCNH5 mRNA | CTD | PMID:31838189 | trichostatin A | decreases expression | EXP | | 6480464 | trichostatin A results in decreased expression of KCNH5 mRNA | CTD | PMID:24935251 | trichostatin A | increases expression | EXP | | 6480464 | trichostatin A results in increased expression of KCNH5 mRNA | CTD | PMID:24935251 | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of KCNH5 mRNA | CTD | PMID:24383497, PMID:26272509 | valproic acid | decreases expression | ISO | RGD:621417 | 6480464 | Valproic Acid results in decreased expression of KCNH5 mRNA | CTD | PMID:29427782 | valproic acid | affects splicing | ISO | RGD:621417 | 6480464 | Valproic Acid affects the splicing of KCNH5 mRNA | CTD | PMID:29427782 | valproic acid | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in decreased expression of KCNH5 mRNA | CTD | PMID:27188386 | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of KCNH5 mRNA | CTD | PMID:28001369 | |