Adh1-ps1 (alcohol dehydrogenase 1C (class I), gamma polypeptide, pseudogene 1) - Rat Genome Database

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Gene: Adh1-ps1 (alcohol dehydrogenase 1C (class I), gamma polypeptide, pseudogene 1) Rattus norvegicus
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Symbol: Adh1-ps1
Name: alcohol dehydrogenase 1C (class I), gamma polypeptide, pseudogene 1
RGD ID: 1595864
Description: Predicted to enable alcohol dehydrogenase (NAD+) activity and zinc ion binding activity. Predicted to be involved in ethanol metabolic process. Predicted to be located in cytoplasm.
Type: pseudo (Ensembl: protein-coding)
RefSeq Status: MODEL
Previously known as: alcohol dehydrogenase 1-like; LOC310902; similar to Alcohol dehydrogenase 1A (Alcohol dehydrogenase alpha subunit)
Related Functional Gene: Adh1c  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82229,536,380 - 229,554,556 (+)NCBIGRCr8
mRatBN7.22226,862,836 - 226,881,171 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2226,862,725 - 226,881,162 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.02243,615,544 - 243,634,663 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02262,153,492 - 262,172,731 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42235,868,290 - 235,886,972 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2219,018,772 - 219,037,941 (+)NCBICelera
Cytogenetic Map2q44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

References

Genomics

Variants

.
Variants in Adh1-ps1
364 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298075Scl17Serum cholesterol level QTL 173.4blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)2211744537249053267Rat
2317752Glom23Glomerulus QTL 233.6urine protein amount (VT:0005160)urine protein level (CMO:0000591)2193452645245889826Rat
2317885Alcrsp28Alcohol response QTL 282.10.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2212828222249053267Rat
738013Alc15Alcohol consumption QTL 154.10.00022consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)2184165752229165752Rat
8694435Bw166Body weight QTL 16614.080.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)2182171407227171407Rat
9589044Scfw1Subcutaneous fat weight QTL 15.80.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)2182171407227171407Rat
8694383Bw158Body weight QTL 1587.690.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)2182171407227171407Rat
7207490Bss111Bone structure and strength QTL 1116.4femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)2211744537249053267Rat
7411555Bw132Body weight QTL 1320.001body mass (VT:0001259)body weight gain (CMO:0000420)2223389739249053267Rat
7207482Bss107Bone structure and strength QTL 1077femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)2211744537249053267Rat
7207484Bss108Bone structure and strength QTL 1085.3femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)2211744537249053267Rat
8694194Abfw1Abdominal fat weight QTL 111.70.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)2182171407227171407Rat
1300126Bp175Blood pressure QTL 1753.46arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2214226044247136170Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
1549836Bss2Bone structure and strength QTL 27.5femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)2211744537249053267Rat
1581499Esta2Estrogen-induced thymic atrophy QTL 2thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2189599258226936289Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
1598813Memor9Memory QTL 92.7exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2199341726234244620Rat
1598835Anxrr18Anxiety related response QTL 182.98body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)2200990457245990457Rat
61398Bp50Blood pressure QTL 504.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189599258234599258Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
2293833Kiddil8Kidney dilation QTL 82.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2219753301247136170Rat
2293844Kiddil7Kidney dilation QTL 73.5kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2219753301247136170Rat
2298479Eau5Experimental allergic uveoretinitis QTL 50.0021uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)2202446871237938339Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2164073756227146641Rat
1331767Hrtrt12Heart rate QTL 123.373heart pumping trait (VT:2000009)heart rate (CMO:0000002)2218414747240841241Rat
2313073Bmd75Bone mineral density QTL 754.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)2215377404237938339Rat
61366Iddm3Insulin dependent diabetes mellitus QTL 34.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2189599258234599258Rat
9587428Epfw6Epididymal fat weight QTL 67.470.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)2223389739249053267Rat


Expression


Sequence


RefSeq Acc Id: ENSRNOT00000098035   ⟹   ENSRNOP00000079144
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2226,862,725 - 226,881,162 (+)Ensembl
RefSeq Acc Id: XR_005501336
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82229,536,380 - 229,554,556 (+)NCBI
mRatBN7.22226,862,836 - 226,881,171 (+)NCBI
Protein Sequences
Ensembl Protein ENSRNOP00000079144.1
RefSeq Acc Id: ENSRNOP00000079144   ⟸   ENSRNOT00000098035
Protein Domains
Enoyl reductase (ER)

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-51073 BioCyc
Ensembl Genes ENSRNOG00000065373 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000098035.1 UniProtKB/TrEMBL
Gene3D-CATH Medium-chain alcohol dehydrogenases, catalytic domain UniProtKB/TrEMBL
  NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro ADH-like_C UniProtKB/TrEMBL
  ADH_N UniProtKB/TrEMBL
  ADH_Zn_CS UniProtKB/TrEMBL
  GroES-like_sf UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  PKS_ER UniProtKB/TrEMBL
NCBI Gene 310902 ENTREZGENE
PANTHER ALCOHOL DEHYDROGENASE UniProtKB/TrEMBL
  ALCOHOL DEHYDROGENASE 6B (CLASS V) UniProtKB/TrEMBL
Pfam ADH_N UniProtKB/TrEMBL
  ADH_zinc_N UniProtKB/TrEMBL
PhenoGen Adh1-ps1 PhenoGen
PROSITE ADH_ZINC UniProtKB/TrEMBL
RatGTEx ENSRNOG00000065373 RatGTEx
SMART PKS_ER UniProtKB/TrEMBL
Superfamily-SCOP SSF50129 UniProtKB/TrEMBL
  SSF51735 UniProtKB/TrEMBL
UniProt A0A8I5ZM50_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-10 Adh1-ps1  alcohol dehydrogenase 1C (class I), gamma polypeptide, pseudogene 1  LOC310902  similar to Alcohol dehydrogenase 1A (Alcohol dehydrogenase alpha subunit)  Symbol and Name Changed 1299863 APPROVED
2006-11-20 LOC310902  similar to Alcohol dehydrogenase 1A (Alcohol dehydrogenase alpha subunit)      Symbol and Name status set to provisional 70820 PROVISIONAL