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Gene: Plekhd1 (pleckstrin homology and coiled-coil domain containing D1) Rattus norvegicus

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Symbol:

Plekhd1

Name:

pleckstrin homology and coiled-coil domain containing D1

RGD ID:

1566112

Description:

Orthologous to human PLEKHD1 (pleckstrin homology and coiled-coil domain containing D1); INTERACTS WITH 1-naphthyl isothiocyanate; 3,7-dihydropurine-6-thione; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

hypothetical protein LOC500685; LOC500685; PH domain-containing family D member 1; pleckstrin homology domain containing, family D (with coiled-coil domains) member 1; pleckstrin homology domain containing, family D (with M protein repeats) member 1; pleckstrin homology domain-containing family D member 1; RGD1566112; similar to pleckstrin homology domain protein (5V327); UPF0639 protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	106,071,966 - 106,103,250 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	106,071,901 - 106,117,826 (+)	Ensembl				GRCr8
mRatBN7.2	6	100,340,655 - 100,371,942 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	100,340,655 - 100,371,941 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	100,507,523 - 100,538,373 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	100,807,226 - 100,838,072 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	100,181,462 - 100,213,140 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	6	107,340,359 - 107,372,041 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	6	106,747,324 - 106,779,004 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	6	104,540,928 - 104,572,612 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	6	103,695,739 - 103,727,419 (+)	NCBI		F344_StmMcwi
Rnor_6.0	6	104,340,114 - 104,371,162 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	104,340,206 - 104,371,335 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	112,512,063 - 112,543,111 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	104,457,412 - 104,488,508 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	98,198,936 - 98,229,968 (+)	NCBI		Celera
Cytogenetic Map	6	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Breast Neoplasms (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1-naphthyl isothiocyanate (EXP)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,4,4'-trichlorobiphenyl (ISO)

3,7-dihydropurine-6-thione (EXP)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

amitrole (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

carbon nanotube (ISO)

cobalt dichloride (EXP)

copper atom (EXP)

copper(0) (EXP)

diethylstilbestrol (EXP)

dioxygen (ISO)

diquat (ISO)

endosulfan (EXP)

fenvalerate (EXP)

malathion (ISO)

mercaptopurine (EXP)

paraquat (EXP)

PCB138 (ISO)

propiconazole (EXP)

purine-6-thiol (EXP)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

tetrachloromethane (EXP)

tetraphene (ISO)

triptonide (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932

Genomics

Comparative Map Data

Plekhd1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	106,071,966 - 106,103,250 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	106,071,901 - 106,117,826 (+)	Ensembl				GRCr8
mRatBN7.2	6	100,340,655 - 100,371,942 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	100,340,655 - 100,371,941 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	100,507,523 - 100,538,373 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	100,807,226 - 100,838,072 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	100,181,462 - 100,213,140 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	6	107,340,359 - 107,372,041 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	6	106,747,324 - 106,779,004 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	6	104,540,928 - 104,572,612 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	6	103,695,739 - 103,727,419 (+)	NCBI		F344_StmMcwi
Rnor_6.0	6	104,340,114 - 104,371,162 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	104,340,206 - 104,371,335 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	112,512,063 - 112,543,111 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	104,457,412 - 104,488,508 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	98,198,936 - 98,229,968 (+)	NCBI		Celera
Cytogenetic Map	6	q24	NCBI

PLEKHD1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	69,467,744 - 69,531,551 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	69,484,692 - 69,531,551 (+)	Ensembl			hg38	GRCh38
GRCh37	14	69,951,445 - 69,998,268 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	69,021,162 - 69,089,065 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	14	50,015,608 - 50,059,327 (+)	NCBI		Celera
Cytogenetic Map	14	q24.1	NCBI
HuRef	14	50,120,506 - 50,164,233 (+)	NCBI		HuRef
CHM1_1	14	69,889,605 - 69,933,346 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	63,680,891 - 63,744,716 (+)	NCBI		T2T-CHM13v2.0

Plekhd1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	80,739,375 - 80,770,990 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	80,739,365 - 80,770,988 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	12	80,692,601 - 80,724,216 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	80,692,591 - 80,724,214 (+)	Ensembl			mm10	GRCm38
MGSCv37	12	81,793,588 - 81,825,203 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	12	81,611,433 - 81,643,062 (+)	NCBI		MGSCv36	mm8
Celera	12	82,157,906 - 82,189,561 (+)	NCBI		Celera
Cytogenetic Map	12	C3	NCBI
cM Map	12	36.96	NCBI

Plekhd1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955466	852,958 - 878,814 (-)	Ensembl
ChiLan1.0	NW_004955466	853,902 - 878,813 (-)	NCBI	ChiLan1.0	ChiLan1.0

PLEKHD1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	70,609,529 - 70,656,060 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	69,826,043 - 69,872,573 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	50,079,139 - 50,125,677 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	68,952,074 - 68,996,526 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	68,952,074 - 68,996,526 (+)	Ensembl			panPan2	panpan1.1

PLEKHD1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	43,280,201 - 43,308,671 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	43,279,447 - 43,307,320 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	42,969,688 - 43,001,905 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	43,510,120 - 43,542,350 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	43,509,915 - 43,538,479 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	43,124,748 - 43,157,173 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	43,199,035 - 43,231,147 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	43,558,549 - 43,590,767 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Plekhd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	61,461,805 - 61,500,078 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936495	12,691,524 - 12,730,227 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936495	12,691,693 - 12,729,776 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PLEKHD1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	93,152,946 - 93,187,598 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	7	93,152,946 - 93,187,730 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	99,429,665 - 99,464,317 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PLEKHD1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	46,722,510 - 46,768,134 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	46,722,657 - 46,770,343 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666053	34,943,923 - 34,998,826 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Plekhd1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	31,556,906 - 31,594,990 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624734	31,556,897 - 31,593,247 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Plekhd1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	7	94,907,903 - 94,937,773 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Plekhd1
268 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	423
Count of miRNA genes:	237
Interacting mature miRNAs:	280
Transcripts:	ENSRNOT00000058301
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2293088	Iddm28	Insulin dependent diabetes mellitus QTL 28	5.21		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	6	68767270	135411972	Rat
1331799	Bp211	Blood pressure QTL 211	3.66407		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	88019181	136741135	Rat
1358355	Srcrt4	Stress Responsive Cort QTL 4	6.39		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	106095977	147156653	Rat
61329	Eae9	Experimental allergic encephalomyelitis QTL 9	3.7		body mass (VT:0001259)	change in body weight (CMO:0002045)	6	84490437	129490437	Rat
2313399	Anxrr28	Anxiety related response QTL 28			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	6	101593607	138161926	Rat
1331725	Bp212	Blood pressure QTL 212	3.52475		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	99437079	125323237	Rat
1331789	Rf37	Renal function QTL 37	3.224		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	6	86494122	112380234	Rat
1331722	Thshl1	Thyroid stimulating hormone level QTL 1	11.7	0.0001	blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	6	99708426	112483760	Rat
4145119	Mcs25	Mammary carcinoma susceptibility QTL 25		0.0001	mammary gland integrity trait (VT:0010552)	ratio of deaths to total study population during a period of time (CMO:0001023)	6	71278722	116278722	Rat
70176	Mcsm1	Mammary carcinoma susceptibility modifier QTL 1			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	64367996	109367996	Rat
1581563	Uae33	Urinary albumin excretion QTL 33			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	93560258	136550638	Rat
10054138	Gmadr3	Adrenal mass QTL 3	3.68	0.00045	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	6	90871046	135871046	Rat
1641917	Colcr5	Colorectal carcinoma resistance QTL 5	3.18	0.0009	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	6	98944780	143944780	Rat
61414	Pia3	Pristane induced arthritis QTL 3	4.5		joint integrity trait (VT:0010548)	post-insult time to onset of experimental arthritis (CMO:0001450)	6	100704576	136029228	Rat
724524	Uae2	Urinary albumin excretion QTL 2	2.7	0.0005	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	79198463	144254945	Rat
737827	Hcar11	Hepatocarcinoma resistance QTL 11	4.4		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	6	46050607	116278722	Rat
2303624	Vencon5	Ventilatory control QTL 5	4.45		respiration trait (VT:0001943)	minute ventilation (CMO:0000132)	6	93778632	138778632	Rat
1576309	Emca7	Estrogen-induced mammary cancer QTL 7	4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	20859430	113082285	Rat
2293837	Kiddil1	Kidney dilation QTL 1	3.7		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	86867923	110125012	Rat
2293842	Kiddil3	Kidney dilation QTL 3	4.3		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	86867923	110125012	Rat
10054123	Srcrt6	Stress Responsive Cort QTL 6	2.5	0.0043	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	90871046	135871046	Rat
724536	Uae7	Urinary albumin excretion QTL 7	3.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	93560258	136550638	Rat
1576302	Schws4	Schwannoma susceptibility QTL 4		0.0078	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	78204640	123204640	Rat
1581550	Pur8	Proteinuria QTL 8			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	93560258	136550638	Rat
1300075	Glom7	Glomerulus QTL 7	5.6	0.0000002	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	6	76937178	121937178	Rat
12801471	Schws9	Schwannoma susceptibility QTL 9			nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	101593607	146593607	Rat

Markers in Region

D6Rat103

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	6	106,095,977 - 106,096,209 (+)	Marker Load Pipeline
mRatBN7.2	6	100,364,669 - 100,364,901 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	104,363,890 - 104,364,121	NCBI	Rnor6.0
Rnor_5.0	6	112,535,839 - 112,536,070	UniSTS	Rnor5.0
RGSC_v3.4	6	104,481,235 - 104,481,467	RGD	RGSC3.4
RGSC_v3.4	6	104,481,236 - 104,481,467	UniSTS	RGSC3.4
Celera	6	98,222,696 - 98,222,927	UniSTS
RGSC_v3.1	6	104,484,691 - 104,484,923	RGD
SHRSP x BN Map	6	57.8998	UniSTS
SHRSP x BN Map	6	57.8998	RGD
FHH x ACI Map	6	68.02	RGD
Cytogenetic Map	6	q24	UniSTS

D6Uwm2

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	100,353,533 - 100,353,682 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	104,352,757 - 104,352,905	NCBI	Rnor6.0
Rnor_5.0	6	112,524,706 - 112,524,854	UniSTS	Rnor5.0
RGSC_v3.4	6	104,470,103 - 104,470,251	UniSTS	RGSC3.4
Celera	6	98,211,563 - 98,211,711	UniSTS
RGSC_v3.1	6	104,473,558 - 104,473,707	RGD
Cytogenetic Map	6	q24	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
10	16	12	105	235	74	73	48	126	42	22	410	273	11	206	81	92	31	15	15

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001127566	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC161896	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473982	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000058301 ⟹ ENSRNOP00000055103

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	106,071,901 - 106,103,367 (+)	Ensembl
mRatBN7.2 Ensembl	6	100,340,655 - 100,371,941 (+)	Ensembl
Rnor_6.0 Ensembl	6	104,340,206 - 104,371,335 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000122193 ⟹ ENSRNOP00000100662

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	106,084,903 - 106,103,367 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000135334 ⟹ ENSRNOP00000111239

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	106,071,901 - 106,117,826 (+)	Ensembl

RefSeq Acc Id:

NM_001127566 ⟹ NP_001121038

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	106,071,966 - 106,103,250 (+)	NCBI
mRatBN7.2	6	100,340,655 - 100,371,942 (+)	NCBI
Dahl_SR_JrHsd	6	107,340,359 - 107,372,041 (+)	NCBI
Lyon_Normotensive	6	106,747,324 - 106,779,004 (+)	NCBI
Lyon_Hypertensive	6	104,540,928 - 104,572,612 (+)	NCBI
F344_StmMcwi	6	103,695,739 - 103,727,419 (+)	NCBI
Rnor_6.0	6	104,340,114 - 104,371,162 (+)	NCBI
Rnor_5.0	6	112,512,063 - 112,543,111 (+)	NCBI
RGSC_v3.4	6	104,457,412 - 104,488,508 (+)	RGD
Celera	6	98,198,936 - 98,229,968 (+)	RGD

Sequence:

show sequence

GGCGGCGCTCCGGAGATTCGCCCCAGCGGCTGGCTAAGCTTCCCGCGCCCCTCCGCTCACCGCC
CCGCTCGTCGGGATTCGCGCCCCGACGGCGTCCCCTGCTGCCCGCACTGGCCGTGCCCACTGCT
TCCCACGGCCCTCCCTATCCCTTCCAATCCCACGAAGGGAGTGGGTCCTGCCGGGGCAGAGTCT
TCTAGACACGATGTTCACATCTAAGTCCAACTCCGTGTCGCCATCGCCGTCCCTGGAGCAGGCC
GACGCGGACGCGCTGGACATCAGCACCAAAGTGCAGCTCTATGGGGTTCTGTGGAAGCGGCCGT
TCGGGAGATCGTCGGCCAAGTGGTCCCGGCGGTTTTTCATCATCAAAGAAAGCTTTCTGCTTTA
CTACTCTGAGAGTGAGAGGAAGAGTTTTGAAACCAATAAATACTTCAACATCCATCCTAAGGGT
GTCATCCCACTGGGTGGCTGCCTGGTGGAGGCCAGAGAAGAGCCCAGCATGCCCTATGCCATGA
AGATCTCACACCAGGACTTTCATGGGAATGTCCTGTTGGCTGCTGAGTCTGAGTTTGAGCAGAC
ACAATGGCTTGAGATGCTTCAGGAGTCTGGGAAGGTGACCTGGAAAAATGCCCAGCTAGGAGAA
GCTATGATCAAAAGCCTAGAGGCACAGGGGCTACAGCTGGCTAAGGAAAAACAGGAATATTTAG
ACAAGCTGATGGAGGAGACAGAAGAGCTGTGCCTTCAGAGGGAGCAGAGAGAGGAGCTTGAGCG
CCTGAACCAGGTGCTGGAGGCTGAGAAGCAGCAGTTTGAGGAGGTGGTGCAAGAGCTGAAAGTG
GAGCAGGAGCAGATCAAGAGGGAGCTAGAACTCACGGCAAGATGCCTCAAGGGTGTGGAGCAAG
AGAAGAAGGAGCTGAGGCACCTCACAGAATCCTTACAGCACACACTGGAGGAACTCTCCATAGA
GAAGAAGAAAACCCTAGAGATGCTGGAGGAAGATAAGAACCAGCCACAGCCCTTGACCAATCAG
AGTGAACAGCCACCAGCCACTGATGGTCTCCATAGCAACCTCAGGCAGATCGAAGAGCGGATGC
AGGAGCTTTTGGCAGAGAAGCTTCTGGCTGAGAAGCGGATGAAGGAGAATGAGGAACGCTCACG
GGCCCTGGAGGAGGAACGGGAGTTCTACTCAAGCCAGTCTCAAGCCCTGCAGAACTCGCTGCAG
GAGCTGACCGCAGAGAAGCAGCAGGCTGAGCAGGAACTCAAGGCTGAAGTGAAAGTACGCATGG
ACCTTGAGAGACGACTTCGGGAGGCAGAGGCAGCCTTGCGGAGCCTGGAACAAGGCCTCAATTC
CAAGGTTCGGAACAAGGAGAAGGAAGAGAGGATGCGGGCTGATGTGAGCCACCTGAAAAGGTTT
TTCGAGGAGTGCATCCGGAATGCAGAGCTGGAGGCCAAGATGCCAGTCATCATGAAGAACTCGG
TGTACATCCACAAGGCGGCCACTCGCCGTATCAAGAGCTGCCGTTTCCATCGACGACGGTCTAG
CACTTCCTGGAATGACATGAAGCCATCCCAGTCCTTCATGACCTCCCAGCTAGAAGCCAACAAC
ATAGAGGAGCTGAAGGAGGTGGCCAAGCGGCTAAGCAGAGACCAGCGCTTCCGGGAATCCATCT
ATCACATCATGGCCACCCAGCCTGGGGCCTCTGCACTTCCCCGGGGAGGAAAGTAATGGGAACG
CCTCCCCTACCTCCTGTCTTTCCTTGGTGGGGCAGCAGGGAGGTCTGATTCCCCTTGGTCCTTT
CCAGCAGAGCACTACCAGGAGAGGGGCACCCTCATTCTCAAAGGAGGTAATACCTCTCTGCCTC
ACCCGGAGCCCTGACCTTGGAGGTCAGAAGGGAGCATTGGAAGAGAGCACTGGATTCCCTGGAA
CTGGAGTCATGGGTGGTTGTGAGCTATAGTGTGGGTGCTGGGAACCAAATCTGGGTCCTCTGAA
AGAGCGGCAAGTTCTCTTAACCACTGAGCCATCTCTCCAGGCCTGAGCCCTGACCTTGGGTTTA
CCCTAGGTAGGGGTAGGTCCACACTGGGTGCTACCTGGTTGTCATGATGAGGCCTGGCTCTGTG
TGGTATCTGTTGGTCAAGAAGAGAAGTTGTCTATTCCACAAGGACTGAAAAGTTCCTCTGGTAC
CCACTGTACCCCCTTGGTGACTCTGCCACTCTGACCCTGGTCCCATGACACCCCCTAACTCTCT
TCGCTCCTGATCCTCCAATTTGTCCAGACCCTGCACTTATTCCATGTCCTTGAGATGGAAAAGC
AGGCCCTGAGACACAAACCCAGGTTCACAGCACCCCACCCCCTCTCTGCCGTATTCCTGGCTGA
AAGGCCACCCAGGTCTCCTAGTCACAAATGGGTTTCTCCAGATACAGCTCCAGCAATCTGCTGG
AGGGTAGCTGCCTCGGGCTCTTGTGACCCTGCCCCCCGGGAGGTCACAGAGATCTGTCTCTCTC
CCAGCTGGCACACCTTGCAGCCTCCTCTTCCTGCAGTGGCCTCACTCAATGAACCAATGCAGCC
AGGAACCCACCACATGGGAGCAGGGACCTGTGGGGAGCCGGTAGCCATTGGTGGGTTCAGTGCT
GTCAGAGTGACACTGTAACACCAGCCTGCAGGTTTTATGGAAGACCACTACCCTTACGAGGCCA
AAGACTGAGGAATGTGTTCCTCATCTGTGAGTCTTTTGGCCCATCCCTCAGAAGCTGCCTGAGT
CTATCAGTCTTGTCAAACAATACTTGGGGAGGGGCGGGGACACATACGGTGGTTAAGAGCACTT
GTTTCTCTTGGGAGGACCCAGACTTGGTTCCCACATGGTAGCTCACAACCATCTGTGACTTCGT
TTGCCAGGAGATCCAACACCCTCTCCTGACCTCCACAGACACCAGGCCCTCCCATGGTGCGTGT
ACACACATGCAGACAAAACATACACATAAAATAGATCCTTAAAAAACACATTTAAAGGGGGCCG
GGTGCTAAGGCAGTGCTGGATCAAAGGCATCCATTTTCTATCAGAAGACTGAAGTGTCCTGAGG
GAGGTACAGAAGTCACTCTGGGGAAGAACCCTTGTCAAGGTCTGGGCTGCCCTGTTCTCCATGG
TTGCTTCTGGGTGGGGTGTTTCGGAGTCAGTGCATCCGAGTGTAAATATAAAACTTTAAGTGTG
TCTAAACCTGCATAAACCCAGAGCTCGTCTTACAAAACATGTATGTGGAATGGACTTTGAAATG
AAGACGTAGAAAACCAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001121038	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI61896	(Get FASTA)	NCBI Sequence Viewer
	B1WBU8	(Get FASTA)	NCBI Sequence Viewer
	EDL81394	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000055103
	ENSRNOP00000055103.2

RefSeq Acc Id:

NP_001121038 ⟸ NM_001127566

- UniProtKB:

B1WBU8 (UniProtKB/Swiss-Prot), A6JDK0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MFTSKSNSVSPSPSLEQADADALDISTKVQLYGVLWKRPFGRSSAKWSRRFFIIKESFLLYYSE
SERKSFETNKYFNIHPKGVIPLGGCLVEAREEPSMPYAMKISHQDFHGNVLLAAESEFEQTQWL
EMLQESGKVTWKNAQLGEAMIKSLEAQGLQLAKEKQEYLDKLMEETEELCLQREQREELERLNQ
VLEAEKQQFEEVVQELKVEQEQIKRELELTARCLKGVEQEKKELRHLTESLQHTLEELSIEKKK
TLEMLEEDKNQPQPLTNQSEQPPATDGLHSNLRQIEERMQELLAEKLLAEKRMKENEERSRALE
EEREFYSSQSQALQNSLQELTAEKQQAEQELKAEVKVRMDLERRLREAEAALRSLEQGLNSKVR
NKEKEERMRADVSHLKRFFEECIRNAELEAKMPVIMKNSVYIHKAATRRIKSCRFHRRRSSTSW
NDMKPSQSFMTSQLEANNIEELKEVAKRLSRDQRFRESIYHIMATQPGASALPRGGK

hide sequence

Ensembl Acc Id:

ENSRNOP00000055103 ⟸ ENSRNOT00000058301

Ensembl Acc Id:

ENSRNOP00000100662 ⟸ ENSRNOT00000122193

Ensembl Acc Id:

ENSRNOP00000111239 ⟸ ENSRNOT00000135334

Protein Domains

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B1WBU8-F1-model_v2	AlphaFold	B1WBU8	1-505	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1566112	AgrOrtholog
BioCyc Gene	G2FUF-36908	BioCyc
Ensembl Genes	ENSRNOG00000038297	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000058301	ENTREZGENE
	ENSRNOT00000058301.5	UniProtKB/Swiss-Prot
Gene3D-CATH	2.30.29.30	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7319876	IMAGE-MGC_LOAD
InterPro	PH-like_dom_sf	UniProtKB/Swiss-Prot
	PH_domain	UniProtKB/Swiss-Prot
KEGG Report	rno:500685	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:187480	IMAGE-MGC_LOAD
NCBI Gene	500685	ENTREZGENE
PANTHER	PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY D MEMBER 1	UniProtKB/Swiss-Prot
	SWAP-70 RECOMBINASE	UniProtKB/Swiss-Prot
Pfam	PF00169	UniProtKB/Swiss-Prot
PhenoGen	Plekhd1	PhenoGen
PROSITE	PH_DOMAIN	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000038297	RatGTEx
SMART	SM00233	UniProtKB/Swiss-Prot
Superfamily-SCOP	PH domain-like	UniProtKB/Swiss-Prot
UniProt	A0ABK0LC37_RAT	UniProtKB/TrEMBL
	A0ABK0LXR1_RAT	UniProtKB/TrEMBL
	A6JDK0	ENTREZGENE, UniProtKB/TrEMBL
	B1WBU8	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-11-30	Plekhd1	pleckstrin homology and coiled-coil domain containing D1	Plekhd1	pleckstrin homology domain containing, family D (with coiled-coil domains) member 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2011-08-02	Plekhd1	pleckstrin homology domain containing, family D (with coiled-coil domains) member 1	Plekhd1	pleckstrin homology domain containing, family D (with M protein repeats) member 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2011-05-27	Plekhd1	pleckstrin homology domain containing, family D (with M protein repeats) member 1	RGD1566112	similar to pleckstrin homology domain protein (5V327)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1566112	similar to pleckstrin homology domain protein (5V327)	RGD1566112_predicted	similar to pleckstrin homology domain protein (5V327) (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-07	RGD1566112_predicted	similar to pleckstrin homology domain protein (5V327) (predicted)	LOC500685	similar to pleckstrin homology domain protein (5V327)	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC500685	similar to pleckstrin homology domain protein (5V327)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD