Frmpd4 (FERM and PDZ domain containing 4) - Rat Genome Database

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Pathways
Gene: Frmpd4 (FERM and PDZ domain containing 4) Rattus norvegicus
Analyze
Symbol: Frmpd4
Name: FERM and PDZ domain containing 4
RGD ID: 1566031
Description: Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity. Involved in postsynaptic actin cytoskeleton organization. Is active in glutamatergic synapse and postsynaptic density. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 104. Orthologous to human FRMPD4 (FERM and PDZ domain containing 4); INTERACTS WITH 17alpha-ethynylestradiol; 3,4-methylenedioxymethamphetamine; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: FERM and PDZ domain-containing protein 4; LOC302656; RGD1566031; similar to KIAA0316 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X29,739,834 - 30,386,917 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX29,368,849 - 30,384,621 (+)EnsemblGRCr8
mRatBN7.2X25,853,849 - 26,814,642 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX25,853,934 - 26,814,637 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX27,701,139 - 27,831,285 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X31,119,411 - 31,249,752 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X27,342,396 - 27,472,510 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X27,231,648 - 28,206,890 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX28,072,826 - 28,204,260 (+)Ensemblrn6Rnor6.0
Rnor_5.0X27,955,922 - 28,600,017 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X47,683,734 - 47,814,085 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX27,055,940 - 27,185,801 (+)NCBICelera
Cytogenetic MapXq13NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Preso, a novel PSD-95-interacting FERM and PDZ domain protein that regulates dendritic spine morphogenesis. Lee HW, etal., J Neurosci. 2008 Dec 31;28(53):14546-56. doi: 10.1523/JNEUROSCI.3112-08.2008.
3. Alterations of mGluR5 and its endogenous regulators Norbin, Tamalin and Preso1 in schizophrenia: towards a model of mGluR5 dysregulation. Matosin N, etal., Acta Neuropathol. 2015 Jul;130(1):119-29. doi: 10.1007/s00401-015-1411-6. Epub 2015 Mar 17.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:22074847   PMID:22561452   PMID:37442439  


Genomics

Comparative Map Data
Frmpd4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X29,739,834 - 30,386,917 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX29,368,849 - 30,384,621 (+)EnsemblGRCr8
mRatBN7.2X25,853,849 - 26,814,642 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX25,853,934 - 26,814,637 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX27,701,139 - 27,831,285 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X31,119,411 - 31,249,752 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X27,342,396 - 27,472,510 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X27,231,648 - 28,206,890 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX28,072,826 - 28,204,260 (+)Ensemblrn6Rnor6.0
Rnor_5.0X27,955,922 - 28,600,017 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X47,683,734 - 47,814,085 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX27,055,940 - 27,185,801 (+)NCBICelera
Cytogenetic MapXq13NCBI
FRMPD4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X11,822,439 - 12,724,523 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX11,822,423 - 12,724,523 (+)Ensemblhg38GRCh38
GRCh37X11,840,558 - 12,742,642 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X12,066,506 - 12,650,450 (+)NCBIBuild 36Build 36hg18NCBI36
CeleraX16,274,012 - 16,856,608 (+)NCBICelera
Cytogenetic MapXp22.2NCBI
HuRefX9,927,416 - 10,509,157 (+)NCBIHuRef
CHM1_1X12,187,174 - 12,773,028 (+)NCBICHM1_1
T2T-CHM13v2.0X11,404,988 - 12,305,982 (+)NCBIT2T-CHM13v2.0
Frmpd4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X166,254,297 - 167,360,230 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX166,254,305 - 167,360,227 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38X167,471,306 - 168,577,241 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX167,471,309 - 168,577,231 (-)Ensemblmm10GRCm38
MGSCv37X163,909,241 - 165,015,165 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X162,815,414 - 163,921,338 (-)NCBIMGSCv36mm8
CeleraX150,648,006 - 151,744,590 (-)NCBICelera
Cytogenetic MapXF5NCBI
cM MapX78.36NCBI
Frmpd4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955544584,686 - 1,151,938 (-)Ensembl
ChiLan1.0NW_004955544586,991 - 1,152,195 (-)NCBIChiLan1.0ChiLan1.0
FRMPD4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X13,926,325 - 14,508,937 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X13,929,974 - 14,512,604 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X4,450,486 - 5,336,784 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X12,399,567 - 12,624,370 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX12,399,479 - 12,622,978 (+)EnsemblpanPan2panpan1.1
FRMPD4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X8,663,015 - 9,229,269 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX8,664,739 - 9,226,025 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX8,619,305 - 9,185,368 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X8,616,367 - 9,181,282 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX8,371,923 - 9,180,672 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X8,599,446 - 9,165,435 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X8,635,573 - 9,205,459 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X8,631,669 - 9,197,726 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Frmpd4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X1,690,540 - 2,469,067 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364701,923,835 - 2,470,564 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364701,923,328 - 2,469,067 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FRMPD4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX8,542,382 - 9,438,821 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1X8,625,039 - 9,451,433 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X10,224,041 - 10,300,128 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FRMPD4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X10,364,458 - 11,213,356 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX10,996,515 - 11,214,725 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605612,408,452 - 13,006,309 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Frmpd4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248821,552,801 - 2,150,894 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248821,554,597 - 2,152,481 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Frmpd4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1X29,316,836 - 29,944,591 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Frmpd4
2767 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:29
Count of miRNA genes:22
Interacting mature miRNAs:28
Transcripts:ENSRNOT00000039796
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598873Memor2Memory QTL 22.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)X2447036044931007Rat
70165Bp64Blood pressure QTL 645.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X400149344939387Rat
2290375Gluco34Glucose level QTL 342.75blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)X2447036045082063Rat
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X197044046970440Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X811148653111486Rat

Markers in Region
DXRat24  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8X29,879,798 - 29,879,948 (+)Marker Load Pipeline
Rnor_6.0X27,696,275 - 27,696,404NCBIRnor6.0
Rnor_5.0X28,096,483 - 28,096,659UniSTSRnor5.0
CeleraX26,693,788 - 26,693,938UniSTS
RH 3.4 MapX334.9UniSTS
RH 3.4 MapX334.9RGD
RH 2.0 Map21254.9RGD
FHH x ACI MapX9.03RGD
Cytogenetic MapXq21UniSTS
DXRat143  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8X30,207,159 - 30,207,301 (+)Marker Load Pipeline
mRatBN7.2X26,634,871 - 26,635,013 (+)MAPPERmRatBN7.2
Rnor_6.0X28,025,522 - 28,025,663NCBIRnor6.0
Rnor_5.0X28,422,769 - 28,422,910UniSTSRnor5.0
RGSC_v3.4X47,636,734 - 47,636,876RGDRGSC3.4
RGSC_v3.4X47,636,735 - 47,636,876UniSTSRGSC3.4
CeleraX27,009,007 - 27,009,155UniSTS
RGSC_v3.1X47,690,203 - 47,690,345RGD
FHH x ACI MapX12.33RGD
FHH x ACI MapX12.33UniSTS
Cytogenetic MapXq21UniSTS
DXRat124  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8X30,207,131 - 30,207,392 (+)Marker Load Pipeline
mRatBN7.2X26,634,843 - 26,635,104 (+)MAPPERmRatBN7.2
Rnor_6.0X28,025,494 - 28,025,754NCBIRnor6.0
Rnor_5.0X28,422,741 - 28,423,001UniSTSRnor5.0
RGSC_v3.4X47,636,706 - 47,636,967RGDRGSC3.4
RGSC_v3.4X47,636,707 - 47,636,967UniSTSRGSC3.4
CeleraX27,008,979 - 27,009,224UniSTS
RGSC_v3.1X47,690,176 - 47,690,436RGD
RH 3.4 MapX339.1UniSTS
RH 3.4 MapX339.1RGD
RH 2.0 Map21264.1RGD
SHRSP x BN MapX7.97RGD
Cytogenetic MapXq21UniSTS
DXGot23  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X26,440,728 - 26,440,937 (+)MAPPERmRatBN7.2
Rnor_6.0X27,830,258 - 27,830,466NCBIRnor6.0
Rnor_5.0X28,227,501 - 28,227,709UniSTSRnor5.0
RGSC_v3.4X47,438,309 - 47,438,518RGDRGSC3.4
RGSC_v3.4X47,438,310 - 47,438,518UniSTSRGSC3.4
CeleraX26,815,220 - 26,815,428UniSTS
RGSC_v3.1X47,491,779 - 47,491,987RGD
RH 3.4 MapX334.8UniSTS
RH 3.4 MapX334.8RGD
RH 2.0 Map21273.8RGD
Cytogenetic MapXq21UniSTS
DXGot20  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X26,666,219 - 26,666,399 (+)MAPPERmRatBN7.2
Rnor_6.0X28,057,043 - 28,057,222NCBIRnor6.0
Rnor_5.0X28,454,290 - 28,454,469UniSTSRnor5.0
RGSC_v3.4X47,668,079 - 47,668,259RGDRGSC3.4
RGSC_v3.4X47,668,080 - 47,668,259UniSTSRGSC3.4
CeleraX27,040,286 - 27,040,465UniSTS
RGSC_v3.1X47,721,549 - 47,721,728RGD
RH 3.4 MapX310.8UniSTS
RH 3.4 MapX310.8RGD
RH 2.0 Map21275.7RGD
Cytogenetic MapXq21UniSTS
DXGot18  
Rat AssemblyChrPosition (strand)SourceJBrowse
CeleraX26,700,876 - 26,701,116UniSTS
RH 3.4 MapX335.4RGD
RH 3.4 MapX335.4UniSTS
Cytogenetic MapXq21UniSTS
RH144489  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X26,253,167 - 26,253,271 (+)MAPPERmRatBN7.2
Rnor_6.0X27,641,965 - 27,642,068NCBIRnor6.0
Rnor_5.0X28,042,033 - 28,042,136UniSTSRnor5.0
RGSC_v3.4X46,962,852 - 46,962,955UniSTSRGSC3.4
CeleraX26,639,800 - 26,639,903UniSTS
RH 3.4 MapX334.7UniSTS
Cytogenetic MapXq21UniSTS
BF399596  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X26,212,557 - 26,212,652 (+)MAPPERmRatBN7.2
Rnor_6.0X27,601,446 - 27,601,540NCBIRnor6.0
Rnor_5.0X28,001,514 - 28,001,608UniSTSRnor5.0
RGSC_v3.4X46,921,289 - 46,921,383UniSTSRGSC3.4
CeleraX26,598,978 - 26,599,072UniSTS
RH 3.4 MapX334.1UniSTS
Cytogenetic MapXq21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
12 8 17 147 67 67 36 28 36 5 168 68 3 129 45 91 31 14 14

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001106960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001434010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001434011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001434012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001434013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008773161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CS301496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000039796   ⟹   ENSRNOP00000035028
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX29,368,849 - 30,384,621 (+)Ensembl
mRatBN7.2 EnsemblX25,853,934 - 26,811,971 (+)Ensembl
Rnor_6.0 EnsemblX28,072,826 - 28,204,260 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000096626   ⟹   ENSRNOP00000094044
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX29,741,668 - 30,384,371 (+)Ensembl
mRatBN7.2 EnsemblX26,169,141 - 26,811,971 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104697   ⟹   ENSRNOP00000093782
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX29,964,716 - 30,384,371 (+)Ensembl
mRatBN7.2 EnsemblX26,392,393 - 26,811,971 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112961   ⟹   ENSRNOP00000089628
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX29,740,437 - 30,384,621 (+)Ensembl
mRatBN7.2 EnsemblX26,167,996 - 26,814,637 (+)Ensembl
RefSeq Acc Id: NM_001106960   ⟹   NP_001100430
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X30,254,161 - 30,384,243 (+)NCBI
mRatBN7.2X26,681,876 - 26,811,971 (+)NCBI
Rnor_6.0X28,072,821 - 28,204,260 (+)NCBI
Rnor_5.0X27,955,922 - 28,600,017 (+)NCBI
RGSC_v3.4X47,683,734 - 47,814,085 (+)RGD
CeleraX27,055,940 - 27,185,801 (+)RGD
Sequence:
RefSeq Acc Id: XM_017601998   ⟹   XP_017457487
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X29,740,716 - 30,386,917 (+)NCBI
mRatBN7.2X26,168,372 - 26,814,642 (+)NCBI
Rnor_6.0X27,555,025 - 28,206,890 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017601999   ⟹   XP_017457488
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X29,739,834 - 30,386,917 (+)NCBI
mRatBN7.2X26,167,507 - 26,814,642 (+)NCBI
Rnor_6.0X27,554,661 - 28,206,890 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017602000   ⟹   XP_017457489
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X29,740,716 - 30,386,917 (+)NCBI
mRatBN7.2X26,168,372 - 26,814,642 (+)NCBI
Rnor_6.0X27,555,025 - 28,206,890 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039099649   ⟹   XP_038955577
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X29,740,648 - 30,386,917 (+)NCBI
mRatBN7.2X26,167,507 - 26,814,642 (+)NCBI
RefSeq Acc Id: XM_063279930   ⟹   XP_063136000
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X29,740,715 - 30,386,917 (+)NCBI
RefSeq Acc Id: XM_063279931   ⟹   XP_063136001
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X29,740,717 - 30,386,917 (+)NCBI
RefSeq Acc Id: XM_063279932   ⟹   XP_063136002
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X29,739,837 - 30,386,917 (+)NCBI
RefSeq Acc Id: NP_001100430   ⟸   NM_001106960
- UniProtKB: D4A3K7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017457488   ⟸   XM_017601999
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017457489   ⟸   XM_017602000
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017457487   ⟸   XM_017601998
- Peptide Label: isoform X1
- UniProtKB: A0A8I6ALA6 (UniProtKB/TrEMBL),   D4A3K7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000035028   ⟸   ENSRNOT00000039796
RefSeq Acc Id: XP_038955577   ⟸   XM_039099649
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000094044   ⟸   ENSRNOT00000096626
Ensembl Acc Id: ENSRNOP00000093782   ⟸   ENSRNOT00000104697
Ensembl Acc Id: ENSRNOP00000089628   ⟸   ENSRNOT00000112961
RefSeq Acc Id: XP_063136002   ⟸   XM_063279932
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063136000   ⟸   XM_063279930
- Peptide Label: isoform X2
- UniProtKB: D4A3K7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136001   ⟸   XM_063279931
- Peptide Label: isoform X5
Protein Domains
FERM   PDZ   WW

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A3K7-F1-model_v2 AlphaFold D4A3K7 1-1705 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1566031 AgrOrtholog
BioCyc Gene G2FUF-2670 BioCyc
Ensembl Genes ENSRNOG00000004118 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000039796.7 UniProtKB/TrEMBL
  ENSRNOT00000096626 ENTREZGENE
  ENSRNOT00000096626.2 UniProtKB/TrEMBL
  ENSRNOT00000104697 ENTREZGENE
  ENSRNOT00000104697.2 UniProtKB/TrEMBL
  ENSRNOT00000112961 ENTREZGENE
  ENSRNOT00000112961.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.80.10 UniProtKB/TrEMBL
  2.20.70.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  2.30.42.10 UniProtKB/TrEMBL
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/TrEMBL
InterPro Band_41_domain UniProtKB/TrEMBL
  FAK1-like_FERM_C UniProtKB/TrEMBL
  FERM/acyl-CoA-bd_prot_3-hlx UniProtKB/TrEMBL
  FERM_2 UniProtKB/TrEMBL
  FERM_central UniProtKB/TrEMBL
  FERM_domain UniProtKB/TrEMBL
  FRMPD1/3/4_FERM_C UniProtKB/TrEMBL
  PDZ/DHR/GLGF UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
  PH_dom-like UniProtKB/TrEMBL
  Ubiquitin-rel_dom UniProtKB/TrEMBL
  WW_dom UniProtKB/TrEMBL
  WW_dom_sf UniProtKB/TrEMBL
KEGG Report rno:302656 UniProtKB/TrEMBL
NCBI Gene 302656 ENTREZGENE
PANTHER FERM AND PDZ DOMAIN-CONTAINING PROTEIN 4 UniProtKB/TrEMBL
  FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER UniProtKB/TrEMBL
Pfam FERM_C_FAK1 UniProtKB/TrEMBL
  FERM_M UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
PhenoGen Frmpd4 PhenoGen
PROSITE FERM_3 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  WW_DOMAIN_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004118 RatGTEx
SMART B41 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
Superfamily-SCOP FERM_3-hlx UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PH domain-like UniProtKB/TrEMBL
  SSF51045 UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
UniProt A0A8I6ALA6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ALF4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GKT4_RAT UniProtKB/TrEMBL
  A6K2F7_RAT UniProtKB/TrEMBL
  D4A3K7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-07 Frmpd4  FERM and PDZ domain containing 4  RGD1566031_predicted  similar to KIAA0316 protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1566031_predicted  similar to KIAA0316 protein (predicted)  LOC302656  similar to KIAA0316 protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC302656  similar to KIAA0316 protein      Symbol and Name status set to provisional 70820 PROVISIONAL