FRMPD4 (FERM and PDZ domain containing 4) - Rat Genome Database

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Gene: FRMPD4 (FERM and PDZ domain containing 4) Pan paniscus
Analyze
Symbol: FRMPD4
Name: FERM and PDZ domain containing 4
RGD ID: 11796325
Description: ENCODES a protein that exhibits phosphatidylinositol-4,5-bisphosphate binding (inferred); INVOLVED IN positive regulation of synapse structural plasticity (ortholog); postsynaptic actin cytoskeleton organization (ortholog); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynaptic density (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: FERM and PDZ domain-containing protein 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X13,926,325 - 14,508,937 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X13,929,974 - 14,512,604 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X4,450,486 - 5,336,784 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X12,399,567 - 12,624,370 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX12,399,479 - 12,622,978 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FRMPD4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X13,926,325 - 14,508,937 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X13,929,974 - 14,512,604 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X4,450,486 - 5,336,784 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X12,399,567 - 12,624,370 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX12,399,479 - 12,622,978 (+)Ensemblpanpan1.1panPan2
FRMPD4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X11,822,439 - 12,724,523 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX11,822,423 - 12,724,523 (+)EnsemblGRCh38hg38GRCh38
GRCh37X11,840,558 - 12,742,642 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X12,066,506 - 12,650,450 (+)NCBINCBI36Build 36hg18NCBI36
CeleraX16,274,012 - 16,856,608 (+)NCBICelera
Cytogenetic MapXp22.2NCBI
HuRefX9,927,416 - 10,509,157 (+)NCBIHuRef
CHM1_1X12,187,174 - 12,773,028 (+)NCBICHM1_1
T2T-CHM13v2.0X11,404,988 - 12,305,982 (+)NCBIT2T-CHM13v2.0
Frmpd4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X166,254,297 - 167,360,230 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX166,254,305 - 167,360,227 (-)EnsemblGRCm39 Ensembl
GRCm38X167,471,306 - 168,577,241 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX167,471,309 - 168,577,231 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X163,909,241 - 165,015,165 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X162,815,414 - 163,921,338 (-)NCBIMGSCv36mm8
CeleraX150,648,006 - 151,744,590 (-)NCBICelera
Cytogenetic MapXF5NCBI
cM MapX78.36NCBI
Frmpd4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X29,739,834 - 30,386,917 (+)NCBIGRCr8
mRatBN7.2X25,853,849 - 26,814,642 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX25,853,934 - 26,814,637 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX27,701,139 - 27,831,285 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X31,119,411 - 31,249,752 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X27,342,396 - 27,472,510 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X27,231,648 - 28,206,890 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX28,072,826 - 28,204,260 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X27,955,922 - 28,600,017 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X47,683,734 - 47,814,085 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX27,055,940 - 27,185,801 (+)NCBICelera
Cytogenetic MapXq13NCBI
Frmpd4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955544584,686 - 1,151,938 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955544586,991 - 1,152,195 (-)NCBIChiLan1.0ChiLan1.0
FRMPD4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X8,663,015 - 9,229,269 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX8,664,739 - 9,226,025 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX8,619,305 - 9,185,368 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X8,616,367 - 9,181,282 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX8,371,923 - 9,180,672 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X8,599,446 - 9,165,435 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X8,635,573 - 9,205,459 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X8,631,669 - 9,197,726 (+)NCBIUU_Cfam_GSD_1.0
Frmpd4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X1,690,540 - 2,469,067 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364701,923,835 - 2,470,564 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364701,923,328 - 2,469,067 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FRMPD4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX8,542,382 - 9,438,821 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X8,625,039 - 9,451,433 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X10,224,041 - 10,300,128 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FRMPD4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X10,364,458 - 11,213,356 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX10,996,515 - 11,214,725 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605612,408,452 - 13,006,309 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Frmpd4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248821,552,801 - 2,150,894 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248821,554,597 - 2,152,481 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000056139   ⟹   ENSPPAP00000033265
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX12,399,479 - 12,622,978 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000056143   ⟹   ENSPPAP00000033269
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX12,509,044 - 12,621,493 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000056146   ⟹   ENSPPAP00000033272
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX12,509,068 - 12,621,493 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000056149   ⟹   ENSPPAP00000033275
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX12,512,964 - 12,621,493 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000056154   ⟹   ENSPPAP00000033280
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX12,513,450 - 12,622,978 (+)Ensembl
RefSeq Acc Id: XM_034950550   ⟹   XP_034806441
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X13,926,332 - 14,508,937 (+)NCBI
NHGRI_mPanPan1X13,929,993 - 14,512,604 (+)NCBI
Mhudiblu_PPA_v0X4,754,230 - 5,336,780 (+)NCBI
RefSeq Acc Id: XM_034950551   ⟹   XP_034806442
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X13,926,331 - 14,508,937 (+)NCBI
NHGRI_mPanPan1X13,929,992 - 14,512,604 (+)NCBI
Mhudiblu_PPA_v0X4,754,228 - 5,334,119 (+)NCBI
RefSeq Acc Id: XM_034950552   ⟹   XP_034806443
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X13,926,331 - 14,508,937 (+)NCBI
NHGRI_mPanPan1X13,929,992 - 14,512,604 (+)NCBI
Mhudiblu_PPA_v0X4,754,228 - 5,334,119 (+)NCBI
RefSeq Acc Id: XM_034950556   ⟹   XP_034806447
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X13,926,326 - 14,508,937 (+)NCBI
NHGRI_mPanPan1X13,929,975 - 14,512,604 (+)NCBI
Mhudiblu_PPA_v0X4,755,344 - 5,336,784 (+)NCBI
RefSeq Acc Id: XM_057301097   ⟹   XP_057157080
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X13,926,325 - 14,508,937 (+)NCBI
NHGRI_mPanPan1X13,929,974 - 14,512,604 (+)NCBI
RefSeq Acc Id: XM_057301098   ⟹   XP_057157081
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X13,926,325 - 14,508,937 (+)NCBI
NHGRI_mPanPan1X13,929,974 - 14,512,604 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_034806443   ⟸   XM_034950552
- Peptide Label: isoform X3
RefSeq Acc Id: XP_034806442   ⟸   XM_034950551
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034806441   ⟸   XM_034950550
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034806447   ⟸   XM_034950556
- Peptide Label: isoform X4
- UniProtKB: A0A2R9BXR5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000033265   ⟸   ENSPPAT00000056139
RefSeq Acc Id: ENSPPAP00000033275   ⟸   ENSPPAT00000056149
RefSeq Acc Id: ENSPPAP00000033269   ⟸   ENSPPAT00000056143
RefSeq Acc Id: ENSPPAP00000033272   ⟸   ENSPPAT00000056146
RefSeq Acc Id: ENSPPAP00000033280   ⟸   ENSPPAT00000056154
RefSeq Acc Id: XP_057157081   ⟸   XM_057301098
- Peptide Label: isoform X6
- UniProtKB: A0A2R9BXR5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_057157080   ⟸   XM_057301097
- Peptide Label: isoform X5
- UniProtKB: A0A2R9BXR5 (UniProtKB/TrEMBL)
Protein Domains
FERM   PDZ   WW


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000039486 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000056139.1 UniProtKB/TrEMBL
  ENSPPAT00000056143.1 UniProtKB/TrEMBL
  ENSPPAT00000056146.1 UniProtKB/TrEMBL
  ENSPPAT00000056149.1 UniProtKB/TrEMBL
  ENSPPAT00000056154.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.80.10 UniProtKB/TrEMBL
  2.20.70.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  2.30.42.10 UniProtKB/TrEMBL
InterPro Band_41_domain UniProtKB/TrEMBL
  FAK1-like_FERM_C UniProtKB/TrEMBL
  FERM/acyl-CoA-bd_prot_sf UniProtKB/TrEMBL
  FERM_2 UniProtKB/TrEMBL
  FERM_central UniProtKB/TrEMBL
  FERM_domain UniProtKB/TrEMBL
  FRMPD1/3/4_FERM_C UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
  WW_dom UniProtKB/TrEMBL
NCBI Gene FRMPD4 ENTREZGENE
PANTHER FERM AND PDZ DOMAIN-CONTAINING PROTEIN 4 UniProtKB/TrEMBL
  FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER UniProtKB/TrEMBL
Pfam FERM_C_FAK1 UniProtKB/TrEMBL
  FERM_M UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
PROSITE FERM_3 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  WW_DOMAIN_2 UniProtKB/TrEMBL
SMART B41 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF47031 UniProtKB/TrEMBL
  SSF50156 UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
UniProt A0A2R9BUC8_PANPA UniProtKB/TrEMBL
  A0A2R9BXR5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BXS6_PANPA UniProtKB/TrEMBL
  A0A2R9BXS7_PANPA UniProtKB/TrEMBL
  A0A2R9C3Y0_PANPA UniProtKB/TrEMBL