Frmpd4 (FERM and PDZ domain containing 4) - Rat Genome Database

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Gene: Frmpd4 (FERM and PDZ domain containing 4) Mus musculus
Analyze
Symbol: Frmpd4
Name: FERM and PDZ domain containing 4
RGD ID: 1617215
MGI Page MGI
Description: Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in positive regulation of synapse structural plasticity and postsynaptic actin cytoskeleton organization. Is active in glutamatergic synapse and postsynaptic density. Is expressed in dorsal root ganglion; facial ganglion; lateral ventricle choroid plexus; metencephalon part of 4th ventricle choroid plexus; and trigeminal ganglion. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 104. Orthologous to human FRMPD4 (FERM and PDZ domain containing 4).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: FERM and PDZ domain-containing protein 4; Gm196; P; PDZ domain-containing protein 10; Pdzd1; Pdzd10; Pdzk1; Pdzk10; PK; PKAP1; Pr; preso; Preso1; PSD-95-interacting regulator of spine morphogenesis
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X166,254,297 - 167,360,230 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX166,254,305 - 167,360,227 (-)EnsemblGRCm39 Ensembl
GRCm38X167,471,306 - 168,577,241 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX167,471,309 - 168,577,231 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X163,909,241 - 165,015,165 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X162,815,414 - 163,921,338 (-)NCBIMGSCv36mm8
CeleraX150,648,006 - 151,744,590 (-)NCBICelera
Cytogenetic MapXF5NCBI
cM MapX78.36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
2. Mouse MP Annotation Import Pipeline RGD automated import pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12693553   PMID:14610273   PMID:16141072   PMID:16141073   PMID:19118189   PMID:21267068  
PMID:21677750   PMID:21873635   PMID:22074847   PMID:22561452   PMID:22627790   PMID:29267967   PMID:30523785   PMID:31235685   PMID:35930666   PMID:36417873   PMID:36604605   PMID:37816598  
PMID:38355793  


Genomics

Comparative Map Data
Frmpd4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X166,254,297 - 167,360,230 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX166,254,305 - 167,360,227 (-)EnsemblGRCm39 Ensembl
GRCm38X167,471,306 - 168,577,241 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX167,471,309 - 168,577,231 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X163,909,241 - 165,015,165 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X162,815,414 - 163,921,338 (-)NCBIMGSCv36mm8
CeleraX150,648,006 - 151,744,590 (-)NCBICelera
Cytogenetic MapXF5NCBI
cM MapX78.36NCBI
FRMPD4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X11,822,439 - 12,724,523 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX11,822,423 - 12,724,523 (+)EnsemblGRCh38hg38GRCh38
GRCh37X11,840,558 - 12,742,642 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X12,066,506 - 12,650,450 (+)NCBINCBI36Build 36hg18NCBI36
CeleraX16,274,012 - 16,856,608 (+)NCBICelera
Cytogenetic MapXp22.2NCBI
HuRefX9,927,416 - 10,509,157 (+)NCBIHuRef
CHM1_1X12,187,174 - 12,773,028 (+)NCBICHM1_1
T2T-CHM13v2.0X11,404,988 - 12,305,982 (+)NCBIT2T-CHM13v2.0
Frmpd4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X29,739,834 - 30,386,917 (+)NCBIGRCr8
mRatBN7.2X25,853,849 - 26,814,642 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX25,853,934 - 26,814,637 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX27,701,139 - 27,831,285 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X31,119,411 - 31,249,752 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X27,342,396 - 27,472,510 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X27,231,648 - 28,206,890 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX28,072,826 - 28,204,260 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X27,955,922 - 28,600,017 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X47,683,734 - 47,814,085 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX27,055,940 - 27,185,801 (+)NCBICelera
Cytogenetic MapXq13NCBI
Frmpd4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955544584,686 - 1,151,938 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955544586,991 - 1,152,195 (-)NCBIChiLan1.0ChiLan1.0
FRMPD4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X13,926,325 - 14,508,937 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X13,929,974 - 14,512,604 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X4,450,486 - 5,336,784 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X12,399,567 - 12,624,370 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX12,399,479 - 12,622,978 (+)Ensemblpanpan1.1panPan2
FRMPD4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X8,663,015 - 9,229,269 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX8,664,739 - 9,226,025 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX8,619,305 - 9,185,368 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X8,616,367 - 9,181,282 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX8,371,923 - 9,180,672 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X8,599,446 - 9,165,435 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X8,635,573 - 9,205,459 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X8,631,669 - 9,197,726 (+)NCBIUU_Cfam_GSD_1.0
Frmpd4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X1,690,540 - 2,469,067 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364701,923,835 - 2,470,564 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364701,923,328 - 2,469,067 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FRMPD4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX8,542,382 - 9,438,821 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X8,625,039 - 9,451,433 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X10,224,041 - 10,300,128 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FRMPD4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X10,364,458 - 11,213,356 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX10,996,515 - 11,214,725 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605612,408,452 - 13,006,309 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Frmpd4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248821,552,801 - 2,150,894 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248821,554,597 - 2,152,481 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Frmpd4
29402 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4632
Count of miRNA genes:759
Interacting mature miRNAs:1010
Transcripts:ENSMUST00000112145, ENSMUST00000112146, ENSMUST00000112147, ENSMUST00000112149
Prediction methods:Miranda, Pita
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10401118Pgia39_mproteoglycan induced arthritis 39 (mouse)Not determinedX144474380169476592Mouse
1302000Pgia25_mproteoglycan induced arthritis 2 (mouse)Not determinedX144474380169476592Mouse

Markers in Region
02.MHAa50e2.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X168,460,054 - 168,460,220UniSTSGRCm38
MGSCv37X164,897,986 - 164,898,152UniSTSGRCm37
CeleraX151,632,747 - 151,632,913UniSTS
Cytogenetic MapXF5UniSTS
Whitehead_YACX UniSTS
MTH763  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X168,561,523 - 168,561,672UniSTSGRCm38
MGSCv37X164,999,455 - 164,999,604UniSTSGRCm37
CeleraX151,729,062 - 151,729,211UniSTS
Cytogenetic MapXF5UniSTS
cM MapX72.7UniSTS
Whitehead GeneticX59.0UniSTS
DXMit29  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X167,906,434 - 167,906,583UniSTSGRCm38
MGSCv37X164,344,366 - 164,344,515UniSTSGRCm37
CeleraX151,082,457 - 151,082,604UniSTS
Cytogenetic MapXF5UniSTS
cM MapX73.3UniSTS
Whitehead GeneticX59.0UniSTS
Whitehead/MRC_RHX1955.72UniSTS
Whitehead_YACX UniSTS
DXMit30  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X168,412,387 - 168,412,505UniSTSGRCm38
MGSCv37X164,850,319 - 164,850,437UniSTSGRCm37
CeleraX151,585,009 - 151,585,127UniSTS
Cytogenetic MapXF5UniSTS
cM MapX73.3UniSTS
Whitehead GeneticX59.0UniSTS
Whitehead_YACX UniSTS
DXMit71.1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X168,353,525 - 168,353,647UniSTSGRCm38
MGSCv37X164,791,457 - 164,791,579UniSTSGRCm37
CeleraX151,527,231 - 151,527,353UniSTS
Cytogenetic MapXF5UniSTS
cM MapX72.4UniSTS
cM MapX UniSTS
Whitehead_YACX UniSTS
DXMit71  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X168,353,326 - 168,353,444UniSTSGRCm38
MGSCv37X164,791,258 - 164,791,376UniSTSGRCm37
CeleraX151,527,032 - 151,527,150UniSTS
Cytogenetic MapXF5UniSTS
cM MapX72.4UniSTS
Whitehead GeneticX59.0UniSTS
Whitehead/MRC_RHX1962.33UniSTS
20.MMHAP25FLG2.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X167,601,878 - 167,602,071UniSTSGRCm38
MGSCv37X164,039,810 - 164,040,003UniSTSGRCm37
CeleraX150,778,004 - 150,778,197UniSTS
Cytogenetic MapXF5UniSTS
Whitehead/MRC_RHX1955.72UniSTS
RH144489  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X168,036,628 - 168,036,732UniSTSGRCm38
MGSCv37X164,474,560 - 164,474,664UniSTSGRCm37
CeleraX151,212,286 - 151,212,390UniSTS
Cytogenetic MapXF5UniSTS
UniSTS:238112  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X167,776,093 - 167,776,267UniSTSGRCm38
MGSCv37X164,214,025 - 164,214,199UniSTSGRCm37
CeleraX150,951,497 - 150,951,671UniSTS
Cytogenetic MapXF5UniSTS
px-16h2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X167,673,271 - 167,673,532UniSTSGRCm38
MGSCv37X164,111,203 - 164,111,464UniSTSGRCm37
CeleraX150,849,470 - 150,849,731UniSTS
Cytogenetic MapXF5UniSTS
px-40b2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X168,006,156 - 168,006,428UniSTSGRCm38
MGSCv37X164,444,088 - 164,444,360UniSTSGRCm37
Cytogenetic MapXF5UniSTS
px-56a12  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X168,408,292 - 168,408,468UniSTSGRCm38
MGSCv37X164,846,224 - 164,846,400UniSTSGRCm37
CeleraX151,580,920 - 151,581,096UniSTS
Cytogenetic MapXF5UniSTS
px-63e8  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X168,084,298 - 168,084,513UniSTSGRCm38
MGSCv37X164,522,230 - 164,522,445UniSTSGRCm37
CeleraX151,259,471 - 151,259,686UniSTS
Cytogenetic MapXF5UniSTS
px-28c8  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X168,368,149 - 168,368,299UniSTSGRCm38
MGSCv37X164,806,081 - 164,806,231UniSTSGRCm37
CeleraX151,541,855 - 151,542,005UniSTS
Cytogenetic MapXF5UniSTS
px-56a9  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X167,923,912 - 167,924,015UniSTSGRCm38
MGSCv37X164,361,844 - 164,361,947UniSTSGRCm37
CeleraX151,099,700 - 151,099,803UniSTS
Cytogenetic MapXF5UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001033330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001290427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001290428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001359072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001368936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001369234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006528885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006528888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006528889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011247832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011247833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011247834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036161994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK038542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK122244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL669945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL672186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL731729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL807744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL807773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL807785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC139429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX284694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX294438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX546498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ104300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ116157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ251567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000112145   ⟹   ENSMUSP00000107773
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX166,254,309 - 166,680,554 (-)Ensembl
GRCm38.p6 EnsemblX167,471,313 - 167,897,558 (-)Ensembl
Ensembl Acc Id: ENSMUST00000112146   ⟹   ENSMUSP00000107774
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX166,256,969 - 166,905,822 (-)Ensembl
GRCm38.p6 EnsemblX167,473,973 - 168,122,826 (-)Ensembl
Ensembl Acc Id: ENSMUST00000112147   ⟹   ENSMUSP00000107775
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX166,254,305 - 167,360,227 (-)Ensembl
GRCm38.p6 EnsemblX167,471,309 - 168,577,231 (-)Ensembl
Ensembl Acc Id: ENSMUST00000112149   ⟹   ENSMUSP00000107777
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX166,256,431 - 166,906,326 (-)Ensembl
GRCm38.p6 EnsemblX167,473,435 - 168,123,330 (-)Ensembl
Ensembl Acc Id: ENSMUST00000238211   ⟹   ENSMUSP00000158917
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX166,254,305 - 166,638,073 (-)Ensembl
GRCm38.p6 EnsemblX167,471,309 - 167,855,077 (-)Ensembl
Ensembl Acc Id: ENSMUST00000238709   ⟹   ENSMUSP00000158713
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX166,256,969 - 167,231,038 (-)Ensembl
GRCm38.p6 EnsemblX167,473,973 - 168,448,042 (-)Ensembl
Ensembl Acc Id: ENSMUST00000239138   ⟹   ENSMUSP00000159190
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX166,258,294 - 166,907,286 (-)Ensembl
GRCm38.p6 EnsemblX167,475,298 - 168,124,290 (-)Ensembl
RefSeq Acc Id: NM_001033330   ⟹   NP_001028502
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X166,254,302 - 167,360,227 (-)NCBI
GRCm38X167,471,306 - 168,577,231 (-)NCBI
MGSCv37X163,909,241 - 165,015,165 (-)RGD
CeleraX150,648,003 - 151,744,590 (-)NCBI
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001290427   ⟹   NP_001277356
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X166,254,302 - 166,906,258 (-)NCBI
GRCm38X167,471,306 - 168,123,262 (-)NCBI
CeleraX150,648,003 - 151,744,590 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001290428   ⟹   NP_001277357
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X166,254,302 - 166,638,073 (-)NCBI
GRCm38X167,471,306 - 167,855,077 (-)NCBI
CeleraX150,648,003 - 151,744,590 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001359072   ⟹   NP_001346001
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X166,254,302 - 166,907,382 (-)NCBI
GRCm38X167,471,306 - 168,124,386 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001368936   ⟹   NP_001355865
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X166,254,303 - 166,905,937 (-)NCBI
GRCm38X167,471,307 - 168,122,941 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001369234   ⟹   NP_001356163
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X166,254,302 - 167,360,230 (-)NCBI
GRCm38X167,471,306 - 168,577,234 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006528885   ⟹   XP_006528948
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X166,254,778 - 167,231,540 (-)NCBI
GRCm38X167,471,782 - 168,448,533 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006528888   ⟹   XP_006528951
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X166,254,778 - 166,907,410 (-)NCBI
GRCm38X167,471,782 - 168,124,513 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006528889   ⟹   XP_006528952
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X166,254,778 - 166,640,096 (-)NCBI
GRCm38X167,471,782 - 167,857,088 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011247832   ⟹   XP_011246134
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X166,254,778 - 166,907,409 (-)NCBI
GRCm38X167,471,782 - 168,123,262 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011247833   ⟹   XP_011246135
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X166,254,778 - 166,907,409 (-)NCBI
GRCm38X167,471,782 - 168,124,512 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011247834   ⟹   XP_011246136
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X166,254,778 - 167,230,967 (-)NCBI
GRCm38X167,471,782 - 168,447,969 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036161994   ⟹   XP_036017887
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X166,254,297 - 167,231,161 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001028502   ⟸   NM_001033330
- Peptide Label: isoform a
- UniProtKB: Q80U41 (UniProtKB/Swiss-Prot),   Q3UHI9 (UniProtKB/Swiss-Prot),   Q3UHE4 (UniProtKB/Swiss-Prot),   B9EIG4 (UniProtKB/Swiss-Prot),   A2AFR3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006528948   ⟸   XM_006528885
- Peptide Label: isoform X1
- UniProtKB: A0A571BG68 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006528951   ⟸   XM_006528888
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006528952   ⟸   XM_006528889
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: NP_001277356   ⟸   NM_001290427
- Peptide Label: isoform a
- UniProtKB: Q80U41 (UniProtKB/Swiss-Prot),   Q3UHI9 (UniProtKB/Swiss-Prot),   Q3UHE4 (UniProtKB/Swiss-Prot),   B9EIG4 (UniProtKB/Swiss-Prot),   A2AFR3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001277357   ⟸   NM_001290428
- Peptide Label: isoform b
- UniProtKB: Q80U41 (UniProtKB/Swiss-Prot),   Q3UHI9 (UniProtKB/Swiss-Prot),   Q3UHE4 (UniProtKB/Swiss-Prot),   B9EIG4 (UniProtKB/Swiss-Prot),   A2AFR3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011246136   ⟸   XM_011247834
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011246135   ⟸   XM_011247833
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011246134   ⟸   XM_011247832
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: NP_001356163   ⟸   NM_001369234
- Peptide Label: isoform d
- UniProtKB: A0A571BG68 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001346001   ⟸   NM_001359072
- Peptide Label: isoform c
- UniProtKB: Q80U41 (UniProtKB/Swiss-Prot),   Q3UHI9 (UniProtKB/Swiss-Prot),   Q3UHE4 (UniProtKB/Swiss-Prot),   B9EIG4 (UniProtKB/Swiss-Prot),   A2AFR3 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001355865   ⟸   NM_001368936
- Peptide Label: isoform 5
- UniProtKB: A0A589MR22 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000159190   ⟸   ENSMUST00000239138
Ensembl Acc Id: ENSMUSP00000107773   ⟸   ENSMUST00000112145
Ensembl Acc Id: ENSMUSP00000107775   ⟸   ENSMUST00000112147
Ensembl Acc Id: ENSMUSP00000107774   ⟸   ENSMUST00000112146
Ensembl Acc Id: ENSMUSP00000107777   ⟸   ENSMUST00000112149
Ensembl Acc Id: ENSMUSP00000158917   ⟸   ENSMUST00000238211
Ensembl Acc Id: ENSMUSP00000158713   ⟸   ENSMUST00000238709
RefSeq Acc Id: XP_036017887   ⟸   XM_036161994
- Peptide Label: isoform X5
- UniProtKB: Q80U41 (UniProtKB/Swiss-Prot),   Q3UHI9 (UniProtKB/Swiss-Prot),   Q3UHE4 (UniProtKB/Swiss-Prot),   B9EIG4 (UniProtKB/Swiss-Prot),   A2AFR3 (UniProtKB/Swiss-Prot)
Protein Domains
FERM   PDZ   WW

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A2AFR3-F1-model_v2 AlphaFold A2AFR3 1-1320 view protein structure

Promoters
RGD ID:6845724
Promoter ID:MM_KWN:62748
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:ENSMUST00000058979
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X164,167,731 - 164,168,231 (-)MPROMDB
RGD ID:6845723
Promoter ID:MM_KWN:62753
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:ENSMUST00000112149
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X164,560,756 - 164,561,457 (-)MPROMDB
RGD ID:13681860
Promoter ID:EPDNEW_M25079
Type:initiation region
Name:Frmpd4_1
Description:Mus musculus FERM and PDZ domain containing 4 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M25080  EPDNEW_M25081  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X167,855,042 - 167,855,102EPDNEW
RGD ID:13681862
Promoter ID:EPDNEW_M25080
Type:multiple initiation site
Name:Frmpd4_3
Description:Mus musculus FERM and PDZ domain containing 4 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M25079  EPDNEW_M25081  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X168,122,921 - 168,122,981EPDNEW
RGD ID:13681864
Promoter ID:EPDNEW_M25081
Type:single initiation site
Name:Frmpd4_2
Description:Mus musculus FERM and PDZ domain containing 4 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M25079  EPDNEW_M25080  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X168,502,274 - 168,502,334EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3042378 AgrOrtholog
Ensembl Genes ENSMUSG00000049176 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000112145 ENTREZGENE
  ENSMUST00000112145.3 UniProtKB/Swiss-Prot
  ENSMUST00000112146 ENTREZGENE
  ENSMUST00000112146.9 UniProtKB/TrEMBL
  ENSMUST00000112147.9 UniProtKB/TrEMBL
  ENSMUST00000112149.9 UniProtKB/Swiss-Prot
  ENSMUST00000238211 ENTREZGENE
  ENSMUST00000238211.2 UniProtKB/Swiss-Prot
  ENSMUST00000238709 ENTREZGENE
  ENSMUST00000238709.2 UniProtKB/TrEMBL
  ENSMUST00000239138.2 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.80.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.20.70.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.42.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Band_41_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FAK1-like_FERM_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM/acyl-CoA-bd_prot_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM_central UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FRMPD1/3/4_FERM_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WW_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WW_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:333605 UniProtKB/Swiss-Prot
MGD MGI:3042378 ENTREZGENE
NCBI Gene Frmpd4 ENTREZGENE
PANTHER FERM AND PDZ DOMAIN-CONTAINING PROTEIN 4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FERM_C_FAK1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM_M UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Frmpd4 PhenoGen
PROSITE FERM_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WW_DOMAIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART B41 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47031 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50156 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF51045 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54236 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A571BG68 ENTREZGENE, UniProtKB/TrEMBL
  A0A589MR22 ENTREZGENE, UniProtKB/TrEMBL
  A0A589MR67_MOUSE UniProtKB/TrEMBL
  A2AFR3 ENTREZGENE
  B9EIG4 ENTREZGENE
  FRPD4_MOUSE UniProtKB/Swiss-Prot
  Q3UHE4 ENTREZGENE
  Q3UHI9 ENTREZGENE
  Q80U41 ENTREZGENE
UniProt Secondary B9EIG4 UniProtKB/Swiss-Prot
  Q3UHE4 UniProtKB/Swiss-Prot
  Q3UHI9 UniProtKB/Swiss-Prot
  Q80U41 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-26 Frmpd4  FERM and PDZ domain containing 4  Pdzk10  PDZ domain containing 10  Symbol and/or name updated 27372883 PROVISIONAL
2024-08-21 Pdzk10  PDZ domain containing 10  Frmpd4  FERM and PDZ domain containing 4  Symbol and/or name change 5135510 APPROVED