Mospd2 (motile sperm domain containing 2)

Advanced Search (OLGA)

Gene: Mospd2 (motile sperm domain containing 2) Rattus norvegicus

Analyze

Symbol:

Mospd2

Name:

motile sperm domain containing 2

RGD ID:

1563952

Description:

Predicted to enable FFAT motif binding activity. Predicted to be involved in lipid droplet formation; positive regulation of leukocyte chemotaxis; and protein homooligomerization. Predicted to be located in endoplasmic reticulum membrane; organelle membrane contact site; and plasma membrane. Predicted to be active in endomembrane system and endoplasmic reticulum-endosome membrane contact site. Orthologous to human MOSPD2 (motile sperm domain containing 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

hypothetical protein LOC363463; LOC363463; motile sperm domain-containing protein 2; RGD1563952; similar to Mospd2 protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MOSPD2 (motile sperm domain containing 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Mospd2 (motile sperm domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Mospd2 (motile sperm domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MOSPD2 (motile sperm domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MOSPD2 (motile sperm domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Mospd2 (motile sperm domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MOSPD2 (motile sperm domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MOSPD2 (motile sperm domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Mospd2 (motile sperm domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	MOSPD2 (motile sperm domain containing 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Mospd2 (motile sperm domain containing 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	mospd2 (motile sperm domain containing 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	CSR1	Alliance	DIOPT (OrthoFinder\|OrthoInspector)
Drosophila melanogaster (fruit fly):	CG32407	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG33523	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	hpo-28	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	mospd2	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	33,052,063 - 33,105,550 (+)	NCBI		GRCr8
mRatBN7.2	X	29,420,485 - 29,472,099 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	29,420,586 - 29,462,398 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	30,466,543 - 30,508,388 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	33,890,184 - 33,932,013 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	30,090,847 - 30,132,698 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	31,140,967 - 31,182,823 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	31,140,960 - 31,182,816 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	31,520,477 - 31,562,135 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	50,160,231 - 50,202,085 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	29,778,938 - 29,819,862 (+)	NCBI		Celera
Cytogenetic Map	X	q14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Fanconi anemia (ISO)

multiple congenital anomalies-hypotonia-seizures syndrome 2 (ISO)

Neurodevelopmental Disorders (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2-hydroxypropanoic acid (ISO)

3,4-methylenedioxymethamphetamine (ISO)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

bisphenol A (EXP)

C60 fullerene (EXP)

cisplatin (ISO)

clorgyline (ISO)

cobalt dichloride (ISO)

copper atom (ISO)

copper(0) (ISO)

crocidolite asbestos (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

doxorubicin (ISO)

finasteride (EXP)

flutamide (EXP)

FR900359 (ISO)

gentamycin (EXP)

glafenine (EXP)

glyphosate (EXP)

isoprenaline (ISO)

leflunomide (EXP)

methyl methanesulfonate (ISO)

nickel atom (ISO)

paracetamol (ISO)

pentachlorophenol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

rac-lactic acid (ISO)

sodium arsenite (ISO)

succimer (ISO)

sunitinib (ISO)

tetrachloroethene (ISO)

tetrachloromethane (ISO)

tremolite asbestos (ISO)

trichostatin A (ISO)

triphenyl phosphate (ISO)

valdecoxib (EXP)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

lipid droplet formation (ISO)

positive regulation of monocyte chemotaxis (ISO)

positive regulation of neutrophil chemotaxis (ISO)

protein homooligomerization (ISO)

Cellular Component

endomembrane system (IBA)

endoplasmic reticulum (ISO)

endoplasmic reticulum membrane (ISO)

endoplasmic reticulum-endosome membrane contact site (IBA,ISO)

organelle membrane contact site (ISO)

plasma membrane (ISO)

Molecular Function

FFAT motif binding (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:19946888	PMID:28137892

Genomics

Comparative Map Data

Mospd2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	33,052,063 - 33,105,550 (+)	NCBI		GRCr8
mRatBN7.2	X	29,420,485 - 29,472,099 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	29,420,586 - 29,462,398 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	30,466,543 - 30,508,388 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	33,890,184 - 33,932,013 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	30,090,847 - 30,132,698 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	31,140,967 - 31,182,823 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	31,140,960 - 31,182,816 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	31,520,477 - 31,562,135 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	50,160,231 - 50,202,085 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	29,778,938 - 29,819,862 (+)	NCBI		Celera
Cytogenetic Map	X	q14	NCBI

MOSPD2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	14,873,421 - 14,922,327 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	14,873,421 - 14,922,327 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	14,891,543 - 14,940,449 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	14,801,484 - 14,849,378 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	14,651,219 - 14,699,113	NCBI
Celera	X	19,006,911 - 19,054,670 (+)	NCBI		Celera
Cytogenetic Map	X	p22.2	NCBI
HuRef	X	12,649,660 - 12,698,200 (+)	NCBI		HuRef
CHM1_1	X	14,921,937 - 14,969,882 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	14,453,939 - 14,503,195 (+)	NCBI		T2T-CHM13v2.0

Mospd2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	163,719,165 - 163,763,501 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	163,719,165 - 163,763,371 (-)	Ensembl		GRCm39 Ensembl
GRCm38	X	164,936,169 - 164,980,505 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	164,936,169 - 164,980,375 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	161,376,141 - 161,418,267 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	160,280,274 - 160,324,480 (-)	NCBI		MGSCv36	mm8
Celera	X	148,140,317 - 148,182,431 (-)	NCBI		Celera
Cytogenetic Map	X	F5	NCBI
cM Map	X	76.75	NCBI

Mospd2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955519	3,286,847 - 3,337,286 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955519	3,290,137 - 3,336,817 (-)	NCBI	ChiLan1.0	ChiLan1.0

MOSPD2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	16,673,598 - 16,722,124 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	16,677,263 - 16,726,363 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	7,501,222 - 7,549,523 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	14,786,183 - 14,834,408 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	14,785,436 - 14,828,978 (+)	Ensembl	panpan1.1		panPan2

MOSPD2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	11,147,782 - 11,200,838 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	11,147,958 - 11,200,117 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	11,055,567 - 11,108,667 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	11,109,941 - 11,163,021 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	11,109,927 - 11,163,175 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	11,173,144 - 11,226,167 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	11,164,536 - 11,217,230 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	11,192,117 - 11,245,390 (+)	NCBI		UU_Cfam_GSD_1.0

Mospd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	4,330,321 - 4,374,033 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936470	4,330,323 - 4,374,755 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936470	4,330,400 - 4,373,790 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MOSPD2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	11,409,107 - 11,473,964 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	11,409,157 - 11,473,969 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	12,362,232 - 12,428,379 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MOSPD2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	13,350,639 - 13,399,157 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	13,350,639 - 13,399,311 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666056	15,186,784 - 15,235,301 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mospd2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624944	314,638 - 359,085 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624944	314,787 - 358,570 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Mospd2
124 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	149
Count of miRNA genes:	105
Interacting mature miRNAs:	131
Transcripts:	ENSRNOT00000004494
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1598873	Memor2	Memory QTL 2	2.5		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	X	20990947	41052531	Rat
70165	Bp64	Blood pressure QTL 64	5.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	X	1448129	31706553	Rat
1298071	Edpm12	Estrogen-dependent pituitary mass QTL 12	3.2		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	X	2927898	47927898	Rat
2290375	Gluco34	Glucose level QTL 34	2.75		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	X	20990947	41203591	Rat
731181	Uae27	Urinary albumin excretion QTL 27	2.7	0.0059	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	X	1	43491017	Rat
61430	Cia18	Collagen induced arthritis QTL 18	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	14843113	120568734	Rat
10755455	Coatc13	Coat color QTL 13		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	4406000	49406000	Rat
631666	Iddm5	Insulin dependent diabetes mellitus QTL 5			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	X	4494549	49494549	Rat
71116	Niddm16	Non-insulin dependent diabetes mellitus QTL 16	7.81		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	X	15297802	60297802	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001398727	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006256866	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039099873	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000004494 ⟹ ENSRNOP00000004494

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	29,420,588 - 29,461,460 (+)	Ensembl
Rnor_6.0 Ensembl	X	31,140,978 - 31,182,816 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000084395 ⟹ ENSRNOP00000074561

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	29,420,588 - 29,462,398 (+)	Ensembl
Rnor_6.0 Ensembl	X	31,140,960 - 31,180,594 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000116700 ⟹ ENSRNOP00000081484

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	29,420,586 - 29,461,460 (+)	Ensembl

RefSeq Acc Id:

NM_001398727 ⟹ NP_001385656

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	33,052,187 - 33,094,032 (+)	NCBI
mRatBN7.2	X	29,420,571 - 29,462,415 (+)	NCBI

RefSeq Acc Id:

XM_006256866 ⟹ XP_006256928

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	33,052,063 - 33,093,858 (+)	NCBI
mRatBN7.2	X	29,420,485 - 29,462,415 (+)	NCBI
Rnor_6.0	X	31,140,967 - 31,182,823 (+)	NCBI
Rnor_5.0	X	31,520,477 - 31,562,135 (+)	NCBI

Sequence:

show sequence

TCTTGGTCTACCTTTGGGCTGGGCTGGCTGGTGATGAGACACTTGACTGCCGGCTGTGGAAGGA
GCGAGGGCTACAACTACAATCGATTCCGCGACTGTGACCATGGCCGAGAATAACGCTCAGAATA
AAGCCAAGCTAATCTCTGAGACCCGGCGGAGATTCGAAGCTGAGTATGTGACAGAAAAGTCAGA
GAAATACGATCCACGTGATGTTGAAAGACTCCAGCAAGATGATAACTGGGTTGAAAGTTACTTA
CATTGGAGACATAACGTTGTGGATGAAACACTGAAGATGCTTGATGAGAGTTTTCAGTGGAGGA
AAGAATTGTCTGTCAATGACCTTAGTGAATCCTCTATTCCAAGATGGTTATTAGAACTTGGTGG
TATTTATCTGCACGGTTATGACAAAGAAGGTAACAAATTATTTTGGATTAGAGTGAAGTATCAC
ATAAAAGACCAGAAAACCATAATGGACAAGAAGAAGCTCATAGCATTCTGGCTGGAACGATATG
CCAAGAGAGAAAACGGGAAGCCTATCACAGTGATGTTTGACATGTCCGAAACTGGACTCAATAG
CATAGACATGGACTTTGTACGATTTATCATCAACTGCTTTAAGGTGTATTACCCCAAATACCTC
TCAAAAATAGTCATCTTTGATATGCCTTGGATAATGAATGCTGCTTTCAAAATTGTGAAAAGCT
GGCTTGGCCCTGAAGCAGTAAGTTTGTTGAAGTTTACGAGTAAGAATGAGATCCAGGAGTATGT
CAGTGTGGAATACCTGCCTCCCCACATGGGTGGGACAGATCCTTTCAAGTATAGCTACCCACCA
CTGGTAGATGATGACTTCCAGACACCACTGTGTGAAAATGGGCCCATTGCCAGTGAGGATGAAA
CCTCAAGTAAAGAAGATATAGAAGGTGATGGTAAGGAAACCTTGGAAACGATTTCTAATGAGGA
GCAGCCAGCTCAGTCTGAAAAGAGTAACCCAACTGAGTCTGCTTCCAAAAGAGATGAAAATGAA
AAAGTTGATTCAAAGACGAAACCTTTTAAAAAGCCATTGAGTGTTTTTAAAGGACCCTTATTAC
ACATCAGCCCAGCAGAGGAATTATATTTTGGAAGCATTGAATCTGGGGAGAAGAAAACTCTGAT
AGTGTTGACAAATGTCACCAAAAATATCGTGGCCTTTAAGGTAAGAACCACAGCTCCAGAGAAA
TACAGAGTCAAGCCGAGCAACAGCAGCTGTGATCCCGGAGCTTCGGTTGATATCATTGTTTCCC
CACACGGTGGCTTAACAGTTTCTGCCCAAGACCGGTTTCTCATAATGGCTGCAGAAATGGAGCA
GTCATCTGGCACTGGGCCAGCAGAACTAACTCAGTTCTGGAAAGAAGTTCCAAGAAGCAAAGTG
ATGGAACACAGGTTAAGATGCCATACAGTTGAGAGCAGCAAACCAAACAGTCTGATGCTGAAGG
ACAGCGTTTCTGCCCTGTCAGATAAAACCAGTGAAGATCTGTACCTACAATTTGCCACCTCCAG
ATGTGAAACAGACTGCAGTCCACCCTAAGTGCTGTGCACAGTGTCTGTGTCCCTGTGTGTTCAC
AGTGACTTCCCAAGTGGTAGATTTGGGGCCTTAATATAATCTCATCCCAAAGTATCTGTCCATG
TTTTTGATTCCTCATCAGATGAACAAGCAGTTAATTAGCCAAGATGAGGAGTACAATTGTCCTA
ACAGTGTCCCTTTAACGTTTCATAAGAAAATCATGTTGACACACTAAATACCCTTCTTTGCTTG
TTGTCTGGTCAGTTGAACTGAGTAACATCTTGTTAGCATTTCTGTGTGGTGAATGTGACTAAAA
AGGACTTTGGGAAATTAACATAATGTCAACAGTAACTGAACTCTTCTGCTAATCTTGATTAATC
TATATTGTTACATTTGATTTTTGTCCTGTCTTTATTTGGTTTAGTCTAATCACATGTGCATGAT
TATTTTTGGTATTCTGATCAATAATTTTATCTTTAATCATGTCATTGCCTTTTCATGATCAAAT
TACCAGGGATTTTCATTTCGATTTTTGGTTTCACTCGGGAATGGAAATTAATACATTTTCCATG
AAAACATTAATAAAAGATCATTAGCTTGATCTGCAACTAGCCGAAAATGCAAATGCTGGTAAAC
CTAGTCTCAAATTTCATAAAATCATAACTTTTATATCTTGCCACTAATTTTGACTGGATTTAAT
AGCACTTTATTGTACAATTATAAAAAATATATTCCTAGAATTGTTGCCAGTGTAATTTCTCTAA
TGTTCTGGTGCTTTTCATATATTTTCAGTATTTTTATTACTATATTGGTATTTTCTTTGTATAA
ATTGATCAAAAGAACATGTTTTCTATTTTAATATGTTTTAGAAAATAATTACATTTATGAAATA
AATATCATCAGGAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039099873 ⟹ XP_038955801

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	33,052,063 - 33,105,550 (+)	NCBI
mRatBN7.2	X	29,420,485 - 29,472,099 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001385656	(Get FASTA)	NCBI Sequence Viewer
	XP_006256928	(Get FASTA)	NCBI Sequence Viewer
	XP_038955801	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL90528	(Get FASTA)	NCBI Sequence Viewer
	EDL90529	(Get FASTA)	NCBI Sequence Viewer
	EDL90530	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000004494.6
	ENSRNOP00000074561.1
	ENSRNOP00000081484.1

RefSeq Acc Id:	XP_006256928 ⟸ XM_006256866
- Peptide Label:	isoform X1
- UniProtKB:	A6K2K0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAENNAQNKAKLISETRRRFEAEYVTEKSEKYDPRDVERLQQDDNWVESYLHWRHNVVDETLKM LDESFQWRKELSVNDLSESSIPRWLLELGGIYLHGYDKEGNKLFWIRVKYHIKDQKTIMDKKKL IAFWLERYAKRENGKPITVMFDMSETGLNSIDMDFVRFIINCFKVYYPKYLSKIVIFDMPWIMN AAFKIVKSWLGPEAVSLLKFTSKNEIQEYVSVEYLPPHMGGTDPFKYSYPPLVDDDFQTPLCEN GPIASEDETSSKEDIEGDGKETLETISNEEQPAQSEKSNPTESASKRDENEKVDSKTKPFKKPL SVFKGPLLHISPAEELYFGSIESGEKKTLIVLTNVTKNIVAFKVRTTAPEKYRVKPSNSSCDPG ASVDIIVSPHGGLTVSAQDRFLIMAAEMEQSSGTGPAELTQFWKEVPRSKVMEHRLRCHTVESS KPNSLMLKDSVSALSDKTSEDLYLQFATSRCETDCSPP hide sequence

Ensembl Acc Id:

ENSRNOP00000004494 ⟸ ENSRNOT00000004494

Ensembl Acc Id:

ENSRNOP00000074561 ⟸ ENSRNOT00000084395

RefSeq Acc Id:	XP_038955801 ⟸ XM_039099873
- Peptide Label:	isoform X2
- UniProtKB:	D4A4X7 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000081484 ⟸ ENSRNOT00000116700

RefSeq Acc Id:	NP_001385656 ⟸ NM_001398727
- UniProtKB:	A0A0G2K8D1 (UniProtKB/TrEMBL)

Protein Domains

CRAL-TRIO MSP

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2K8D1-F1-model_v2	AlphaFold	A0A0G2K8D1	1-518	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701793

Promoter ID:

EPDNEW_R12317

Type:

initiation region

Name:

Mospd2_1

Description:

motile sperm domain containing 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	X	31,141,007 - 31,141,067	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1563952	AgrOrtholog
BioCyc Gene	G2FUF-2600	BioCyc
Ensembl Genes	ENSRNOG00000003350	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000004494.6	UniProtKB/TrEMBL
	ENSRNOT00000084395.2	UniProtKB/TrEMBL
	ENSRNOT00000116700.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
	3.40.525.10	UniProtKB/TrEMBL
InterPro	CRAL-bd_TRIO_C	UniProtKB/TrEMBL
	CRAL-TRIO_dom_sf	UniProtKB/TrEMBL
	CRAL/TRIO_N_dom_sf	UniProtKB/TrEMBL
	ER-organelle_contact	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
	Major_sperm	UniProtKB/TrEMBL
	PapD-like	UniProtKB/TrEMBL
NCBI Gene	363463	ENTREZGENE
PANTHER	MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2	UniProtKB/TrEMBL
	MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2	UniProtKB/TrEMBL
Pfam	CRAL_TRIO	UniProtKB/TrEMBL
	Motile_Sperm	UniProtKB/TrEMBL
PhenoGen	Mospd2	PhenoGen
PROSITE	CRAL_TRIO	UniProtKB/TrEMBL
	MSP	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000003350	RatGTEx
SMART	SEC14	UniProtKB/TrEMBL
Superfamily-SCOP	CRAL_TRIO_C	UniProtKB/TrEMBL
	PapD-like	UniProtKB/TrEMBL
	Sec14p_like_N	UniProtKB/TrEMBL
UniProt	A0A0G2K8D1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZT29_RAT	UniProtKB/TrEMBL
	A6K2K0	ENTREZGENE, UniProtKB/TrEMBL
	A6K2K2_RAT	UniProtKB/TrEMBL
	D4A4X7	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2010-05-05	Mospd2	motile sperm domain containing 2	RGD1563952	similar to Mospd2 protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1563952	similar to Mospd2 protein	RGD1563952_predicted	similar to Mospd2 protein (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-07	RGD1563952_predicted	similar to Mospd2 protein (predicted)	LOC363463	similar to Mospd2 protein	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC363463	similar to Mospd2 protein			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar