MOSPD2 (motile sperm domain containing 2) - Rat Genome Database

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Gene: MOSPD2 (motile sperm domain containing 2) Pan paniscus
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Symbol: MOSPD2
Name: motile sperm domain containing 2
RGD ID: 12034269
Description: ENCODES a protein that exhibits FFAT motif binding (inferred); INVOLVED IN lipid droplet formation (inferred); positive regulation of monocyte chemotaxis (inferred); positive regulation of neutrophil chemotaxis (inferred); ASSOCIATED WITH autistic disorder (ortholog); Fanconi anemia (ortholog); multiple congenital anomalies-hypotonia-seizures syndrome 2 (ortholog); FOUND IN endomembrane system (inferred); endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: motile sperm domain-containing protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X16,673,598 - 16,722,124 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X16,677,263 - 16,726,363 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X7,501,222 - 7,549,523 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X14,786,183 - 14,834,408 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX14,785,436 - 14,828,978 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MOSPD2Bonoboautistic disorder  ISOMOSPD2 (Homo sapiens)8554872ClinVar Annotator: match by term: AutismClinVarPMID:21681106 and PMID:30208311
MOSPD2BonoboFanconi anemia  ISOMOSPD2 (Homo sapiens)8554872ClinVar Annotator: match by term: Fanconi anemiaClinVarPMID:28492532
MOSPD2Bonobomultiple congenital anomalies-hypotonia-seizures syndrome 2  ISOMOSPD2 (Homo sapiens)8554872ClinVar Annotator: match by term: Multiple congenital anomalies-hypotonia-seizures syndrome 2ClinVarPMID:24706016 more ...
MOSPD2BonoboNeurodevelopmental Disorders  ISOMOSPD2 (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MOSPD2Bonobolipid droplet formation involved_inIEAUniProtKB:Q8NHP6 and ensembl:ENSP00000369860150520179 EnsemblGO_REF:0000107
MOSPD2Bonobopositive regulation of monocyte chemotaxis involved_inIEAUniProtKB:Q8NHP6 and ensembl:ENSP00000369860150520179 EnsemblGO_REF:0000107
MOSPD2Bonobopositive regulation of neutrophil chemotaxis involved_inIEAUniProtKB:Q8NHP6 and ensembl:ENSP00000369860150520179 EnsemblGO_REF:0000107
MOSPD2Bonoboprotein homooligomerization involved_inIEAUniProtKB:Q8NHP6 and ensembl:ENSP00000369860150520179 EnsemblGO_REF:0000107

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MOSPD2Bonoboendomembrane system located_inIEAPANTHER:PTN000463533150520179 TreeGrafterGO_REF:0000118
MOSPD2Bonoboendoplasmic reticulum located_inIEAUniProtKB:Q8NHP6 and ensembl:ENSP00000369860150520179 EnsemblGO_REF:0000107
MOSPD2Bonoboendoplasmic reticulum membrane located_inIEAUniProtKB:Q8NHP6 and ensembl:ENSP00000369860150520179 EnsemblGO_REF:0000107
MOSPD2Bonoboendoplasmic reticulum-endosome membrane contact site located_inIEAUniProtKB:Q8NHP6 and ensembl:ENSP00000369860150520179 EnsemblGO_REF:0000107
MOSPD2Bonoboendoplasmic reticulum-endosome membrane contact site located_inIEAPANTHER:PTN000463533150520179 TreeGrafterGO_REF:0000118
MOSPD2Bonoboorganelle membrane contact site located_inIEAUniProtKB:Q8NHP6 and ensembl:ENSP00000369860150520179 EnsemblGO_REF:0000107
MOSPD2Bonoboplasma membrane located_inIEAUniProtKB:Q8NHP6 and ensembl:ENSP00000369860150520179 EnsemblGO_REF:0000107

Molecular Function

  

PMID:30032202  



MOSPD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X16,673,598 - 16,722,124 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X16,677,263 - 16,726,363 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X7,501,222 - 7,549,523 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X14,786,183 - 14,834,408 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX14,785,436 - 14,828,978 (+)Ensemblpanpan1.1panPan2
MOSPD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X14,873,421 - 14,922,327 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX14,873,421 - 14,922,327 (+)EnsemblGRCh38hg38GRCh38
GRCh37X14,891,543 - 14,940,449 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X14,801,484 - 14,849,378 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X14,651,219 - 14,699,113NCBI
CeleraX19,006,911 - 19,054,670 (+)NCBICelera
Cytogenetic MapXp22.2NCBI
HuRefX12,649,660 - 12,698,200 (+)NCBIHuRef
CHM1_1X14,921,937 - 14,969,882 (+)NCBICHM1_1
T2T-CHM13v2.0X14,453,939 - 14,503,195 (+)NCBIT2T-CHM13v2.0
Mospd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X163,719,165 - 163,763,501 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX163,719,165 - 163,763,371 (-)EnsemblGRCm39 Ensembl
GRCm38X164,936,169 - 164,980,505 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX164,936,169 - 164,980,375 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X161,376,141 - 161,418,267 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X160,280,274 - 160,324,480 (-)NCBIMGSCv36mm8
CeleraX148,140,317 - 148,182,431 (-)NCBICelera
Cytogenetic MapXF5NCBI
cM MapX76.75NCBI
Mospd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X33,052,063 - 33,105,550 (+)NCBIGRCr8
mRatBN7.2X29,420,485 - 29,472,099 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX29,420,586 - 29,462,398 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX30,466,543 - 30,508,388 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X33,890,184 - 33,932,013 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X30,090,847 - 30,132,698 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X31,140,967 - 31,182,823 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX31,140,960 - 31,182,816 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X31,520,477 - 31,562,135 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X50,160,231 - 50,202,085 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX29,778,938 - 29,819,862 (+)NCBICelera
Cytogenetic MapXq14NCBI
Mospd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555193,286,847 - 3,337,286 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555193,290,137 - 3,336,817 (-)NCBIChiLan1.0ChiLan1.0
MOSPD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X11,147,782 - 11,200,838 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX11,147,958 - 11,200,117 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX11,055,567 - 11,108,667 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X11,109,941 - 11,163,021 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX11,109,927 - 11,163,175 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X11,173,144 - 11,226,167 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X11,164,536 - 11,217,230 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X11,192,117 - 11,245,390 (+)NCBIUU_Cfam_GSD_1.0
Mospd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X4,330,321 - 4,374,033 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364704,330,323 - 4,374,755 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364704,330,400 - 4,373,790 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MOSPD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX11,409,107 - 11,473,964 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X11,409,157 - 11,473,969 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X12,362,232 - 12,428,379 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MOSPD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X13,350,639 - 13,399,157 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX13,350,639 - 13,399,311 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605615,186,784 - 15,235,301 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mospd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624944314,638 - 359,085 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624944314,787 - 358,570 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Ensembl Acc Id: ENSPPAT00000034721   ⟹   ENSPPAP00000012059
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX14,785,436 - 14,828,978 (+)Ensembl
RefSeq Acc Id: XM_003805704   ⟹   XP_003805752
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X16,673,598 - 16,722,124 (+)NCBI
NHGRI_mPanPan1X16,677,263 - 16,726,363 (+)NCBI
Mhudiblu_PPA_v0X7,501,223 - 7,549,523 (+)NCBI
PanPan1.1X14,786,183 - 14,834,408 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063601644   ⟹   XP_063457714
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X16,673,614 - 16,722,124 (+)NCBI
Protein RefSeqs XP_003805752 (Get FASTA)   NCBI Sequence Viewer  
  XP_063457714 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000012059.1
RefSeq Acc Id: XP_003805752   ⟸   XM_003805704
- Peptide Label: isoform X1
- UniProtKB: A0A2R9A5B5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000012059   ⟸   ENSPPAT00000034721
RefSeq Acc Id: XP_063457714   ⟸   XM_063601644
- Peptide Label: isoform X2
- UniProtKB: A0A2R9A5B5 (UniProtKB/TrEMBL)
CRAL-TRIO   MSP



1 to 23 of 23 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSPPAG00000029223 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000034721.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.40.525.10 UniProtKB/TrEMBL
InterPro CRAL-TRIO_dom UniProtKB/TrEMBL
  CRAL-TRIO_dom_sf UniProtKB/TrEMBL
  CRAL/TRIO_N_dom_sf UniProtKB/TrEMBL
  ER-organelle_contact UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  MSP_dom UniProtKB/TrEMBL
  PapD-like_sf UniProtKB/TrEMBL
NCBI Gene MOSPD2 ENTREZGENE
PANTHER MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
  MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
Pfam CRAL_TRIO UniProtKB/TrEMBL
  Motile_Sperm UniProtKB/TrEMBL
PROSITE CRAL_TRIO UniProtKB/TrEMBL
  MSP UniProtKB/TrEMBL
SMART SEC14 UniProtKB/TrEMBL
Superfamily-SCOP SSF46938 UniProtKB/TrEMBL
  SSF49354 UniProtKB/TrEMBL
  SSF52087 UniProtKB/TrEMBL
UniProt A0A2R9A5B5 ENTREZGENE, UniProtKB/TrEMBL
1 to 23 of 23 rows