Jkampl (JNK1/MAPK8 associated membrane protein like) - Rat Genome Database

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Gene: Jkampl (JNK1/MAPK8 associated membrane protein like) Rattus norvegicus
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Symbol: Jkampl
Name: JNK1/MAPK8 associated membrane protein like
RGD ID: 1562515
Description: Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in ERAD pathway. Predicted to be located in membrane. Orthologous to human JKAMP (JNK1/MAPK8 associated membrane protein); INTERACTS WITH acrylamide; bisphenol A; fenvalerate.
Type: protein-coding
RefSeq Status: PREDICTED
Previously known as: hypothetical protein LOC500204; LOC500204; RGD1562515; similar to RIKEN cDNA 4931417E11; uncharacterized protein LOC500204
RGD Orthologs
Mouse
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84107,078,531 - 107,079,631 (-)NCBIGRCr8
mRatBN7.24105,520,442 - 105,521,542 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4105,520,442 - 105,521,542 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4110,893,062 - 110,894,154 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04106,668,164 - 106,669,256 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04105,288,193 - 105,289,285 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04101,392,229 - 101,393,329 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4101,392,229 - 101,393,329 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04166,147,783 - 166,148,883 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44106,795,849 - 106,796,949 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera494,652,250 - 94,653,350 (-)NCBICelera
Cytogenetic Map4q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Jkampl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84107,078,531 - 107,079,631 (-)NCBIGRCr8
mRatBN7.24105,520,442 - 105,521,542 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4105,520,442 - 105,521,542 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4110,893,062 - 110,894,154 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04106,668,164 - 106,669,256 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04105,288,193 - 105,289,285 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04101,392,229 - 101,393,329 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4101,392,229 - 101,393,329 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04166,147,783 - 166,148,883 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44106,795,849 - 106,796,949 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera494,652,250 - 94,653,350 (-)NCBICelera
Cytogenetic Map4q33NCBI
Jkampl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39673,445,563 - 73,446,621 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl673,445,564 - 73,446,650 (-)EnsemblGRCm39 Ensembl
GRCm38673,468,573 - 73,469,667 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl673,468,573 - 73,469,667 (-)EnsemblGRCm38mm10GRCm38
MGSCv37673,418,576 - 73,419,661 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36673,398,091 - 73,399,176 (-)NCBIMGSCv36mm8
Celera675,500,201 - 75,501,286 (-)NCBICelera
Cytogenetic Map6C1NCBI
cM Map632.4NCBI

Variants

.
Variants in Jkampl
2 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:11
Count of miRNA genes:11
Interacting mature miRNAs:11
Transcripts:ENSRNOT00000007636
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)485253748148090731Rat
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)495174120140174120Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)490850165135850165Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
631556Bp135Blood pressure QTL 1350.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)478881294117676292Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470362013132642728Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658115089733Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482798864152731274Rat
724522Bp146Blood pressure QTL 1462.20.0021arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)473630210118630210Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)486730991131730991Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)481192555126192555Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
2300179Bmd50Bone mineral density QTL 505.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)460928534105928534Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)450119848146803430Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)462933508114921294Rat
1578670Bss14Bone structure and strength QTL 1416.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)487327165132327165Rat
2317588Eae27Experimental allergic encephalomyelitis QTL 27nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)4103194805112478794Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)439524264116179656Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)456647873149491524Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
1578662Bss15Bone structure and strength QTL 1519.6femur width (VT:1000666)femoral neck width (CMO:0001695)487327165132327165Rat
2302051Pia28Pristane induced arthritis QTL 285.30.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)473630210118630210Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)459948935154902892Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
738015Pia9Pristane induced arthritis QTL 94.50.048joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)480694870125694870Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)493308457167139447Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)473169846132642728Rat
634334Xhs3X-ray hypersensitivity QTL 310intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)484728680129854654Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)470808386115808386Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)478878504123878504Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)462277855128289560Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)462879517107879517Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)485379421167139601Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)456698790126192555Rat
2306899Bp338Blood pressure QTL 3380.071arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)481006124120102625Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
12798523Anxrr56Anxiety related response QTL 562.830.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)485253748150276390Rat
61434Cia3Collagen induced arthritis QTL 34.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4103194656148194656Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)432583980114627242Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
2 5 2 15 12 13 5 7 5 1 24 13 11 28 8

Sequence


Ensembl Acc Id: ENSRNOT00000007636   ⟹   ENSRNOP00000007636
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4105,520,442 - 105,521,542 (-)Ensembl
Rnor_6.0 Ensembl4101,392,229 - 101,393,329 (-)Ensembl
RefSeq Acc Id: NM_001109242   ⟹   NP_001102712
RefSeq Status: PREDICTED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84107,078,531 - 107,079,631 (-)NCBI
mRatBN7.24105,520,442 - 105,521,542 (-)NCBI
Rnor_6.04101,392,229 - 101,393,329 (-)NCBI
Rnor_5.04166,147,783 - 166,148,883 (-)NCBI
RGSC_v3.44106,795,849 - 106,796,949 (-)RGD
Celera494,652,250 - 94,653,350 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001102712 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL91063 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000007636.1
RefSeq Acc Id: NP_001102712   ⟸   NM_001109242
- UniProtKB: D4A0V1 (UniProtKB/TrEMBL),   A6IAE5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000007636   ⟸   ENSRNOT00000007636

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A0V1-F1-model_v2 AlphaFold D4A0V1 1-305 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693135
Promoter ID:EPDNEW_R3660
Type:initiation region
Name:RGD1562515_1
Description:similar to RIKEN cDNA 4931417E11
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04101,393,253 - 101,393,313EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562515 AgrOrtholog
BioCyc Gene G2FUF-44118 BioCyc
Ensembl Genes ENSRNOG00000024604 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000007636.4 UniProtKB/TrEMBL
InterPro DUF766 UniProtKB/TrEMBL
KEGG Report rno:500204 UniProtKB/TrEMBL
NCBI Gene 500204 ENTREZGENE
PANTHER DUF766 UniProtKB/TrEMBL
  RIKEN CDNA 4931417E11 GENE UniProtKB/TrEMBL
Pfam DUF766 UniProtKB/TrEMBL
PhenoGen Jkampl PhenoGen
RatGTEx ENSRNOG00000024604 RatGTEx
UniProt A6IAE5 ENTREZGENE, UniProtKB/TrEMBL
  D4A0V1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-04-22 Jkampl  JNK1/MAPK8 associated membrane protein like  RGD1562515  similar to RIKEN cDNA 4931417E11  Name and Symbol changed 629549 APPROVED
2008-04-30 RGD1562515  similar to RIKEN cDNA 4931417E11   RGD1562515_predicted  similar to RIKEN cDNA 4931417E11 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1562515_predicted  similar to RIKEN cDNA 4931417E11 (predicted)  LOC500204  similar to RIKEN cDNA 4931417E11  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC500204  similar to RIKEN cDNA 4931417E11      Symbol and Name status set to provisional 70820 PROVISIONAL