Robo3 (roundabout guidance receptor 3) - Rat Genome Database

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Gene: Robo3 (roundabout guidance receptor 3) Rattus norvegicus
Analyze
Symbol: Robo3
Name: roundabout guidance receptor 3
RGD ID: 1311018
Description: Involved in positive regulation of axon guidance. Predicted to be located in axon. Predicted to be active in neuron projection. Orthologous to human ROBO3 (roundabout guidance receptor 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC315564; roundabout homolog 3; roundabout homolog 3 (Drosophila); roundabout, axon guidance receptor, homolog 3; roundabout, axon guidance receptor, homolog 3 (Drosophila)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8845,322,323 - 45,340,466 (-)NCBIGRCr8
mRatBN7.2837,133,542 - 37,151,674 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl837,133,916 - 37,151,315 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx841,150,815 - 41,167,744 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0839,433,875 - 39,450,802 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0837,296,780 - 37,313,715 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0839,892,792 - 39,923,735 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl839,892,792 - 39,907,478 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0839,893,678 - 39,911,529 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4838,668,913 - 38,683,439 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1838,679,386 - 38,715,966 (-)NCBI
Celera837,304,456 - 37,318,986 (+)NCBICelera
Cytogenetic Map8q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
axon  (ISO)
neuron projection  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Robo3.1A suppresses slit-mediated repulsion by triggering degradation of Robo2. Li L, etal., J Neurosci Res. 2014 Jul;92(7):835-46. doi: 10.1002/jnr.23364.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Expression of netrin-1, slit-1 and slit-3 but not of slit-2 after cerebellar and spinal cord lesions. Wehrle R, etal., Eur J Neurosci. 2005 Nov;22(9):2134-44.
Additional References at PubMed
PMID:15084255   PMID:15233918   PMID:18466743   PMID:18986510   PMID:19747951   PMID:19906978   PMID:30843071  


Genomics

Comparative Map Data
Robo3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8845,322,323 - 45,340,466 (-)NCBIGRCr8
mRatBN7.2837,133,542 - 37,151,674 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl837,133,916 - 37,151,315 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx841,150,815 - 41,167,744 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0839,433,875 - 39,450,802 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0837,296,780 - 37,313,715 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0839,892,792 - 39,923,735 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl839,892,792 - 39,907,478 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0839,893,678 - 39,911,529 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4838,668,913 - 38,683,439 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1838,679,386 - 38,715,966 (-)NCBI
Celera837,304,456 - 37,318,986 (+)NCBICelera
Cytogenetic Map8q22NCBI
ROBO3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811124,865,432 - 124,881,471 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11124,865,432 - 124,881,471 (+)EnsemblGRCh38hg38GRCh38
GRCh3711124,735,328 - 124,751,367 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611124,240,492 - 124,256,572 (+)NCBINCBI36Build 36hg18NCBI36
Celera11121,895,484 - 121,911,549 (+)NCBICelera
Cytogenetic Map11q24.2NCBI
HuRef11120,677,663 - 120,693,728 (+)NCBIHuRef
CHM1_111124,621,414 - 124,637,480 (+)NCBICHM1_1
T2T-CHM13v2.011124,894,054 - 124,910,095 (+)NCBIT2T-CHM13v2.0
Robo3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39937,327,341 - 37,344,730 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl937,326,965 - 37,344,542 (-)EnsemblGRCm39 Ensembl
GRCm38937,416,045 - 37,433,436 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl937,415,669 - 37,433,246 (-)EnsemblGRCm38mm10GRCm38
MGSCv37937,223,630 - 37,240,760 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36937,165,835 - 37,179,805 (-)NCBIMGSCv36mm8
Celera934,630,435 - 34,647,581 (-)NCBICelera
Cytogenetic Map9A4NCBI
cM Map920.76NCBI
Robo3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541225,937,624 - 25,953,189 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541225,937,624 - 25,953,458 (+)NCBIChiLan1.0ChiLan1.0
ROBO3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29125,560,773 - 125,576,739 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111126,665,737 - 126,681,637 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011119,692,232 - 119,708,309 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111123,607,268 - 123,623,356 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11123,607,268 - 123,623,356 (+)Ensemblpanpan1.1panPan2
ROBO3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.159,563,353 - 9,579,111 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl59,563,345 - 9,579,289 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha59,608,853 - 9,613,840 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.059,503,132 - 9,508,122 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.159,575,801 - 9,580,788 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.059,546,252 - 9,551,241 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.059,582,695 - 9,587,687 (-)NCBIUU_Cfam_GSD_1.0
Robo3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947107,057,543 - 107,074,263 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367431,305,341 - 1,320,702 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367431,305,108 - 1,321,819 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ROBO3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl952,065,499 - 52,081,625 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1952,065,043 - 52,081,764 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2957,580,550 - 57,597,135 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ROBO3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11116,004,129 - 116,024,691 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1116,008,742 - 116,024,474 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604310,093,762 - 10,106,598 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Robo3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624927872,197 - 887,079 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624927872,197 - 887,316 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Robo3
143 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:583
Count of miRNA genes:243
Interacting mature miRNAs:280
Transcripts:ENSRNOT00000064141
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83085640475856404Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83084815461290444Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1582222Epfw2Epididymal fat weight QTL 23.20.0005epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)83173772976737729Rat
1354627Despr14Despair related QTL 140.0056locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)8768895552688955Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83558203280582032Rat
61337Bp22Blood pressure QTL 225.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815442692818Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
1300146Rf17Renal function QTL 172.9renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)82824291273242912Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)82824291299525068Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83084815482460899Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82720571599103503Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)81933115293965294Rat
724514Uae15Urinary albumin excretion QTL 152.9urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)82950266570386295Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83084815461290444Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)82266233067662330Rat
1359033Bp273Blood pressure QTL 273arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
61358Bp39Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83555193880551938Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)82720571599103503Rat
1331744Bp217Blood pressure QTL 2173.398arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815458482492Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)830848259105647037Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)82720571599103503Rat
1359021Bp271Blood pressure QTL 2711.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82664491246711092Rat
2302367Slep5Serum leptin concentration QTL 53.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)8971246341866876Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)81629044461290444Rat
70206Alc20Alcohol consumption QTL 202drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)83084815440713225Rat
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)8971246341866876Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83084815482460899Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)83018886794457446Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)8873663553736635Rat
1331804Cm30Cardiac mass QTL 303.77443heart mass (VT:0007028)heart wet weight (CMO:0000069)82824291253961020Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83084815482460899Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)8470581049705810Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)8767057852670578Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)8470581049705810Rat
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)8209764047097640Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)8209764047097640Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)8873663553736635Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)8470581049705810Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)8209764047097640Rat
1558646Swd5Spike wave discharge measurement QTL 53.450.00036brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)81490675159906751Rat
2302278Gluco36Glucose level QTL 364.2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)82950266550095447Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)8209764047097640Rat
631648Stl5Serum triglyceride level QTL 540.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)82720571554998217Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83646953599083736Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
631271Lecl1Lens clarity QTL 10.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)81898416884531599Rat
2303564Gluco43Glucose level QTL 433blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)82613018771130187Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)8971222053356647Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83084815482460899Rat
1354595Despr4Despair related QTL 42.160.0036locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)8768895552688955Rat
2303572Insul13Insulin level QTL 132blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)82613018771130187Rat

Markers in Region
D8Cebr1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2837,146,536 - 37,146,695 (+)MAPPERmRatBN7.2
Rnor_6.0839,905,409 - 39,905,567NCBIRnor6.0
Rnor_5.0839,906,295 - 39,906,453UniSTSRnor5.0
RGSC_v3.4838,681,530 - 38,681,688UniSTSRGSC3.4
Celera837,306,209 - 37,306,369UniSTS
Cytogenetic Map8q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 7 21 108 53 53 22 25 22 6 144 66 89 41 52 31

Sequence


Ensembl Acc Id: ENSRNOT00000064141   ⟹   ENSRNOP00000060623
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl837,133,916 - 37,148,446 (-)Ensembl
Rnor_6.0 Ensembl839,892,792 - 39,907,478 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118811   ⟹   ENSRNOP00000094407
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl837,133,916 - 37,151,315 (-)Ensembl
RefSeq Acc Id: NM_001394075   ⟹   NP_001381004
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8845,323,344 - 45,340,222 (-)NCBI
mRatBN7.2837,134,563 - 37,151,448 (-)NCBI
RefSeq Acc Id: XM_017595621   ⟹   XP_017451110
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8845,323,645 - 45,340,466 (-)NCBI
mRatBN7.2837,134,854 - 37,151,665 (-)NCBI
Rnor_6.0839,893,439 - 39,923,735 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063265426   ⟹   XP_063121496
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8845,322,323 - 45,340,465 (-)NCBI
RefSeq Acc Id: XM_063265427   ⟹   XP_063121497
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8845,323,655 - 45,335,130 (-)NCBI
RefSeq Acc Id: XM_063265428   ⟹   XP_063121498
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8845,323,655 - 45,331,987 (-)NCBI
RefSeq Acc Id: XP_017451110   ⟸   XM_017595621
- Peptide Label: isoform X2
- UniProtKB: A6KRL2 (UniProtKB/TrEMBL),   D3ZKA2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000060623   ⟸   ENSRNOT00000064141
Ensembl Acc Id: ENSRNOP00000094407   ⟸   ENSRNOT00000118811
RefSeq Acc Id: NP_001381004   ⟸   NM_001394075
- UniProtKB: A0A8I6AJI9 (UniProtKB/TrEMBL),   A6KRL2 (UniProtKB/TrEMBL),   D3ZKA2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121496   ⟸   XM_063265426
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063121497   ⟸   XM_063265427
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063121498   ⟸   XM_063265428
- Peptide Label: isoform X4
Protein Domains
Fibronectin type-III   Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZKA2-F1-model_v2 AlphaFold D3ZKA2 1-1305 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311018 AgrOrtholog
BioCyc Gene G2FUF-31085 BioCyc
Ensembl Genes ENSRNOG00000030016 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000064141.2 UniProtKB/TrEMBL
  ENSRNOT00000118811.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro FN3_sf UniProtKB/TrEMBL
  FN_III UniProtKB/TrEMBL
  Ig-like UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
NCBI Gene 315564 ENTREZGENE
PANTHER PROTEIN SIDEKICK UniProtKB/TrEMBL
  ROUNDABOUT GUIDANCE RECEPTOR 3 UniProtKB/TrEMBL
Pfam fn3 UniProtKB/TrEMBL
  I-set UniProtKB/TrEMBL
  Ig_3 UniProtKB/TrEMBL
PhenoGen Robo3 PhenoGen
PROSITE FN3 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000030016 RatGTEx
SMART FN3 UniProtKB/TrEMBL
  IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP FN_III-like UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
UniProt A0A8I6AJI9 ENTREZGENE, UniProtKB/TrEMBL
  A6KRL2 ENTREZGENE, UniProtKB/TrEMBL
  D3ZKA2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-01 Robo3  roundabout guidance receptor 3  Robo3  roundabout, axon guidance receptor, homolog 3 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-03-01 Robo3  roundabout, axon guidance receptor, homolog 3 (Drosophila)  Robo3  roundabout homolog 3 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Robo3  roundabout homolog 3 (Drosophila)   Robo3_predicted  roundabout homolog 3 (Drosophila) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Robo3_predicted  roundabout homolog 3 (Drosophila) (predicted)      Symbol and Name status set to approved 70820 APPROVED