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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311018
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Robo3
Name: roundabout guidance receptor 3
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Robo3decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of ROBO3 mRNAPMID:25181051
Robo3multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Testosterone] results in decreased expression of ROBO3 mRNAPMID:26496021
Robo3affects expressionISORobo3 (Mus musculus)6480464CTDbisphenol A affects the expression of ROBO3 mRNAPMID:30951980
Robo3decreases expressionISORobo3 (Mus musculus)6480464CTDbisphenol A results in decreased expression of ROBO3 mRNAPMID:38074096
Robo3multiple interactionsISORobo3 (Mus musculus)6480464CTD[potassium bromate co-treated with bisphenol A] affects the expression of ROBO3 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of ROBO3 mRNA]PMID:27082013
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