Tnip1 (TNFAIP3 interacting protein 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Tnip1 (TNFAIP3 interacting protein 1) Rattus norvegicus
Analyze
Symbol: Tnip1
Name: TNFAIP3 interacting protein 1
RGD ID: 1309380
Description: Predicted to enable identical protein binding activity; mitogen-activated protein kinase binding activity; and polyubiquitin modification-dependent protein binding activity. Predicted to be involved in several processes, including negative regulation of intracellular signal transduction; positive regulation of defense response; and positive regulation of macromolecule metabolic process. Predicted to be located in cytosol and nucleoplasm. Orthologous to human TNIP1 (TNFAIP3 interacting protein 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; C60 fullerene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC363599; TNFAIP3-interacting protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81039,537,759 - 39,585,038 (-)NCBIGRCr8
mRatBN7.21039,037,048 - 39,084,328 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1039,037,058 - 39,077,625 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1043,725,512 - 43,772,420 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01043,215,588 - 43,262,498 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01038,719,300 - 38,766,195 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01040,255,776 - 40,303,092 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1040,255,776 - 40,296,470 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01040,028,044 - 40,075,239 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41040,319,735 - 40,366,764 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11040,333,361 - 40,380,387 (-)NCBI
Celera1038,375,087 - 38,422,139 (-)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
antimycin A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP)
C60 fullerene  (EXP)
caffeine  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
choline  (ISO)
chrysene  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
corosolic acid  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
disulfiram  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
folic acid  (ISO)
folpet  (ISO)
hydrogen peroxide  (ISO)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
methotrexate  (ISO)
methoxychlor  (EXP)
mithramycin  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium dichromate  (ISO)
succimer  (ISO)
sunitinib  (ISO)
tetrachloromethane  (ISO)
thimerosal  (ISO)
triptonide  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
cytosol  (ISO)
nucleoplasm  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9923610   PMID:10385526   PMID:12220502   PMID:16684768   PMID:17632516   PMID:18212736   PMID:20010814   PMID:21988832   PMID:22011580   PMID:25416956   PMID:30561431  


Genomics

Comparative Map Data
Tnip1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81039,537,759 - 39,585,038 (-)NCBIGRCr8
mRatBN7.21039,037,048 - 39,084,328 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1039,037,058 - 39,077,625 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1043,725,512 - 43,772,420 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01043,215,588 - 43,262,498 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01038,719,300 - 38,766,195 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01040,255,776 - 40,303,092 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1040,255,776 - 40,296,470 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01040,028,044 - 40,075,239 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41040,319,735 - 40,366,764 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11040,333,361 - 40,380,387 (-)NCBI
Celera1038,375,087 - 38,422,139 (-)NCBICelera
Cytogenetic Map10q22NCBI
TNIP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385151,029,943 - 151,087,685 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5151,029,945 - 151,093,577 (-)EnsemblGRCh38hg38GRCh38
GRCh375150,409,504 - 150,467,246 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365150,389,699 - 150,441,190 (-)NCBINCBI36Build 36hg18NCBI36
Build 345150,389,709 - 150,440,842NCBI
Celera5146,490,845 - 146,542,340 (-)NCBICelera
Cytogenetic Map5q33.1NCBI
HuRef5145,555,312 - 145,613,010 (-)NCBIHuRef
CHM1_15149,842,296 - 149,900,016 (-)NCBICHM1_1
T2T-CHM13v2.05151,566,421 - 151,624,171 (-)NCBIT2T-CHM13v2.0
Tnip1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391154,801,613 - 54,853,766 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1154,801,611 - 54,853,743 (-)EnsemblGRCm39 Ensembl
GRCm381154,910,787 - 54,962,956 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1154,910,785 - 54,962,917 (-)EnsemblGRCm38mm10GRCm38
MGSCv371154,724,289 - 54,776,440 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361154,754,210 - 54,806,335 (-)NCBIMGSCv36mm8
Celera1159,500,207 - 59,552,322 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1132.13NCBI
Tnip1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554082,594,756 - 2,621,304 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554082,575,324 - 2,621,845 (+)NCBIChiLan1.0ChiLan1.0
TNIP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24146,261,722 - 146,316,360 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15144,400,502 - 144,455,917 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05146,457,347 - 146,514,515 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15152,459,868 - 152,510,540 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5152,459,868 - 152,510,540 (-)Ensemblpanpan1.1panPan2
TNIP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1458,150,734 - 58,200,158 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl458,149,882 - 58,199,644 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha457,902,679 - 57,951,877 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0458,588,813 - 58,638,281 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl458,587,946 - 58,638,594 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1458,406,693 - 58,455,880 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0458,505,144 - 58,554,566 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0459,008,672 - 59,057,916 (+)NCBIUU_Cfam_GSD_1.0
Tnip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213116,912,127 - 116,956,907 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366473,914,887 - 3,959,672 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366473,914,887 - 3,959,698 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNIP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1671,926,133 - 71,979,966 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11671,926,038 - 71,979,969 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21678,291,420 - 78,345,241 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TNIP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12353,586,243 - 53,643,599 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2353,587,008 - 53,621,489 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603424,071,417 - 24,128,708 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tnip1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473340,964,020 - 41,006,381 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tnip1
318 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:134
Count of miRNA genes:98
Interacting mature miRNAs:116
Transcripts:ENSRNOT00000013864
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10538701450387014Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101448701189062041Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101502851360430477Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
6893350Bw99Body weight QTL 990.870.16body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
6893352Bw100Body weight QTL 1000.330.6body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101790711351786432Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101816784163167841Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)101960648364606483Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)101960648364606483Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)101981604299406971Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102132980561345413Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102242750090627625Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
70224Eae3Experimental allergic encephalomyelitis QTL 34.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)102652195761345413Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102652195798952741Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102694462871944628Rat
10402859Bp381Blood pressure QTL 3810.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
2292441Bp308Blood pressure QTL 308arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102845313673453136Rat
1600371Mcs21Mammary carcinoma susceptibility QTL 213mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)102887565052200160Rat
1331762Rf40Renal function QTL 403.873kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)102929950464155584Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103063205375632053Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103122402675632053Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
1576319Cia29Collagen induced arthritis QTL 29joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103397392178973921Rat
61332Eau3Experimental allergic uveoretinitis QTL 30.004uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)103449055945579777Rat
1354614Hpcl1Hepatic cholesterol level QTL 13.3liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)103539226751793994Rat
1358897Stresp6Stress response QTL 64.170.022blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)103539226764155584Rat
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103539245763642539Rat
2317042Aia20Adjuvant induced arthritis QTL 203.38joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)103756507982565079Rat
2317043Aia7Adjuvant induced arthritis QTL 73.82joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)103756507982565079Rat

Markers in Region
D10Rat167  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21039,085,864 - 39,086,127 (+)MAPPERmRatBN7.2
mRatBN7.21039,085,731 - 39,086,272 (+)MAPPERmRatBN7.2
mRatBN7.21039,085,731 - 39,086,127 (+)MAPPERmRatBN7.2
Rnor_6.01040,304,554 - 40,305,353NCBIRnor6.0
Rnor_6.01040,304,554 - 40,304,949NCBIRnor6.0
Rnor_5.01040,076,721 - 40,077,520UniSTSRnor5.0
Rnor_5.01040,076,721 - 40,077,116UniSTSRnor5.0
RGSC_v3.41040,368,246 - 40,368,641UniSTSRGSC3.4
RGSC_v3.41040,368,245 - 40,368,641RGDRGSC3.4
RGSC_v3.11040,381,868 - 40,382,299RGD
Celera1038,423,621 - 38,424,016UniSTS
SHRSP x BN Map1036.2799RGD
SHRSP x BN Map1036.2799UniSTS
Cytogenetic Map10q22UniSTS
AA997285  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21039,037,061 - 39,037,152 (+)MAPPERmRatBN7.2
Rnor_6.01040,255,790 - 40,255,880NCBIRnor6.0
Rnor_5.01040,028,058 - 40,028,148UniSTSRnor5.0
RGSC_v3.41040,319,749 - 40,319,839UniSTSRGSC3.4
Celera1038,375,101 - 38,375,191UniSTS
RH 3.4 Map10412.9UniSTS
Cytogenetic Map10q22UniSTS
AU049805  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21039,081,043 - 39,081,205 (+)MAPPERmRatBN7.2
Rnor_6.01040,299,866 - 40,300,027NCBIRnor6.0
Rnor_5.01040,072,033 - 40,072,194UniSTSRnor5.0
RGSC_v3.41040,363,558 - 40,363,719UniSTSRGSC3.4
Celera1038,418,933 - 38,419,094UniSTS
Cytogenetic Map10q22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 52 36 19 36 8 11 74 35 37 11 8
Low 5 5 5 4
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001108826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006246303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006246304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006246306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006246307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006246310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000013864   ⟹   ENSRNOP00000013864
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1039,037,058 - 39,077,625 (-)Ensembl
Rnor_6.0 Ensembl1040,255,776 - 40,282,881 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000086456   ⟹   ENSRNOP00000071437
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1040,256,327 - 40,296,470 (-)Ensembl
RefSeq Acc Id: NM_001108826   ⟹   NP_001102296
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81039,537,759 - 39,584,961 (-)NCBI
mRatBN7.21039,037,048 - 39,084,250 (-)NCBI
Rnor_6.01040,255,776 - 40,303,072 (-)NCBI
Rnor_5.01040,028,044 - 40,075,239 (-)NCBI
RGSC_v3.41040,319,735 - 40,366,764 (-)RGD
Celera1038,375,087 - 38,422,139 (-)RGD
Sequence:
RefSeq Acc Id: XM_006246303   ⟹   XP_006246365
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81039,537,763 - 39,578,442 (-)NCBI
mRatBN7.21039,037,050 - 39,077,677 (-)NCBI
Rnor_6.01040,255,776 - 40,296,478 (-)NCBI
Rnor_5.01040,028,044 - 40,075,239 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006246306   ⟹   XP_006246368
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81039,537,763 - 39,578,418 (-)NCBI
mRatBN7.21039,037,050 - 39,077,677 (-)NCBI
Rnor_6.01040,255,776 - 40,296,478 (-)NCBI
Rnor_5.01040,028,044 - 40,075,239 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063269496   ⟹   XP_063125566
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81039,537,763 - 39,579,855 (-)NCBI
RefSeq Acc Id: XM_063269497   ⟹   XP_063125567
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81039,537,763 - 39,585,038 (-)NCBI
RefSeq Acc Id: XM_063269498   ⟹   XP_063125568
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81039,537,763 - 39,584,976 (-)NCBI
RefSeq Acc Id: XM_063269499   ⟹   XP_063125569
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81039,537,763 - 39,579,855 (-)NCBI
RefSeq Acc Id: XM_063269500   ⟹   XP_063125570
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81039,537,763 - 39,578,418 (-)NCBI
RefSeq Acc Id: XM_063269501   ⟹   XP_063125571
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81039,537,763 - 39,579,855 (-)NCBI
RefSeq Acc Id: XM_063269502   ⟹   XP_063125572
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81039,537,763 - 39,578,418 (-)NCBI
RefSeq Acc Id: XM_063269503   ⟹   XP_063125573
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81039,537,763 - 39,579,855 (-)NCBI
RefSeq Acc Id: XM_063269504   ⟹   XP_063125574
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81039,537,763 - 39,584,996 (-)NCBI
RefSeq Acc Id: XM_063269505   ⟹   XP_063125575
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81039,537,763 - 39,584,997 (-)NCBI
RefSeq Acc Id: XM_063269506   ⟹   XP_063125576
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81039,537,763 - 39,578,376 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001102296   ⟸   NM_001108826
- UniProtKB: D3ZHV1 (UniProtKB/TrEMBL),   A6HEJ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006246368   ⟸   XM_006246306
- Peptide Label: isoform X2
- UniProtKB: A6HEJ8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006246365   ⟸   XM_006246303
- Peptide Label: isoform X1
- UniProtKB: D3ZHV1 (UniProtKB/TrEMBL),   A6HEJ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000071437   ⟸   ENSRNOT00000086456
RefSeq Acc Id: ENSRNOP00000013864   ⟸   ENSRNOT00000013864
RefSeq Acc Id: XP_063125567   ⟸   XM_063269497
- Peptide Label: isoform X1
- UniProtKB: A6HEJ9 (UniProtKB/TrEMBL),   D3ZHV1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125575   ⟸   XM_063269505
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063125574   ⟸   XM_063269504
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063125568   ⟸   XM_063269498
- Peptide Label: isoform X1
- UniProtKB: A6HEJ9 (UniProtKB/TrEMBL),   D3ZHV1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125573   ⟸   XM_063269503
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063125571   ⟸   XM_063269501
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063125569   ⟸   XM_063269499
- Peptide Label: isoform X2
- UniProtKB: A6HEJ8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125566   ⟸   XM_063269496
- Peptide Label: isoform X1
- UniProtKB: A6HEJ9 (UniProtKB/TrEMBL),   D3ZHV1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125572   ⟸   XM_063269502
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063125570   ⟸   XM_063269500
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063125576   ⟸   XM_063269506
- Peptide Label: isoform X7
Protein Domains
NF-kappa-B essential modulator NEMO CC2-LZ

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZHV1-F1-model_v2 AlphaFold D3ZHV1 1-649 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697197
Promoter ID:EPDNEW_R7718
Type:initiation region
Name:Tnip1_1
Description:TNFAIP3 interacting protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01040,296,435 - 40,296,495EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309380 AgrOrtholog
BioCyc Gene G2FUF-25096 BioCyc
Ensembl Genes ENSRNOG00000010370 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000013864.7 UniProtKB/TrEMBL
Gene3D-CATH Nemo cc2-lz domain - 1d5 darpin complex UniProtKB/TrEMBL
InterPro CC2-LZ_dom UniProtKB/TrEMBL
KEGG Report rno:363599 UniProtKB/TrEMBL
NCBI Gene 363599 ENTREZGENE
PANTHER PTHR31882:SF3 UniProtKB/TrEMBL
  TNFAIP3-INTERACTING PROTEIN COILED COIL FAMILY MEMBER UniProtKB/TrEMBL
Pfam CC2-LZ UniProtKB/TrEMBL
PhenoGen Tnip1 PhenoGen
RatGTEx ENSRNOG00000010370 RatGTEx
UniProt A6HEJ8 ENTREZGENE, UniProtKB/TrEMBL
  A6HEJ9 ENTREZGENE, UniProtKB/TrEMBL
  D3ZHV1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Tnip1  TNFAIP3 interacting protein 1   Tnip1_predicted  TNFAIP3 interacting protein 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Tnip1_predicted  TNFAIP3 interacting protein 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED