Sympk (symplekin scaffold protein) - Rat Genome Database

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Gene: Sympk (symplekin scaffold protein) Rattus norvegicus
Analyze
Symbol: Sympk
Name: symplekin scaffold protein
RGD ID: 1306735
Description: Predicted to be involved in mRNA processing. Predicted to be located in cytosol; nucleus; and plasma membrane. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Orthologous to human SYMPK (symplekin scaffold protein); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; mRNA decay pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hepatocyte nuclear factor 3 gamma; Hfn3g; HNF-3G; LOC292683; symplekin
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8187,800,416 - 87,828,727 (+)NCBIGRCr8
mRatBN7.2178,672,372 - 78,700,684 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl178,672,378 - 78,700,684 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx184,061,441 - 84,089,693 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0192,619,038 - 92,647,306 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0185,816,543 - 85,844,795 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0179,931,097 - 79,959,461 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl179,931,156 - 79,959,461 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0181,190,967 - 81,219,274 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4178,377,890 - 78,407,581 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1178,458,914 - 78,485,679 (+)NCBI
Celera173,138,479 - 73,166,767 (+)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Pre-mRNA 3'-end processing complex assembly and function. Chan S, etal., Wiley Interdiscip Rev RNA. 2011 May-Jun;2(3):321-35. doi: 10.1002/wrna.54. Epub 2010 Oct 18.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Means to an end: mechanisms of alternative polyadenylation of messenger RNA precursors. Gruber AR, etal., Wiley Interdiscip Rev RNA. 2014 Mar-Apr;5(2):183-96. doi: 10.1002/wrna.1206. Epub 2013 Nov 14.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:8769423   PMID:11092755   PMID:12477932   PMID:14707147   PMID:20861839   PMID:29158257  


Genomics

Comparative Map Data
Sympk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8187,800,416 - 87,828,727 (+)NCBIGRCr8
mRatBN7.2178,672,372 - 78,700,684 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl178,672,378 - 78,700,684 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx184,061,441 - 84,089,693 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0192,619,038 - 92,647,306 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0185,816,543 - 85,844,795 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0179,931,097 - 79,959,461 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl179,931,156 - 79,959,461 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0181,190,967 - 81,219,274 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4178,377,890 - 78,407,581 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1178,458,914 - 78,485,679 (+)NCBI
Celera173,138,479 - 73,166,767 (+)NCBICelera
Cytogenetic Map1q21NCBI
SYMPK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381945,815,410 - 45,863,147 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1945,815,410 - 45,863,225 (-)EnsemblGRCh38hg38GRCh38
GRCh371946,318,668 - 46,366,405 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361951,010,540 - 51,058,388 (-)NCBINCBI36Build 36hg18NCBI36
Build 341951,010,561 - 51,058,207NCBI
Celera1943,123,735 - 43,171,584 (-)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1942,747,182 - 42,795,062 (-)NCBIHuRef
CHM1_11946,321,187 - 46,369,025 (-)NCBICHM1_1
T2T-CHM13v2.01948,642,851 - 48,690,585 (-)NCBIT2T-CHM13v2.0
Sympk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39718,758,321 - 18,788,542 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl718,758,302 - 18,788,543 (+)EnsemblGRCm39 Ensembl
GRCm38719,024,377 - 19,054,623 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,024,377 - 19,054,618 (+)EnsemblGRCm38mm10GRCm38
MGSCv37719,609,726 - 19,639,971 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36718,182,787 - 18,213,145 (+)NCBIMGSCv36mm8
Celera716,436,068 - 16,466,273 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.46NCBI
Sympk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955574261,056 - 292,652 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955574264,312 - 292,616 (-)NCBIChiLan1.0ChiLan1.0
SYMPK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22051,981,047 - 52,029,161 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11953,852,369 - 53,900,555 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01942,824,847 - 42,872,867 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11951,361,502 - 51,409,167 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1951,361,502 - 51,410,212 (-)Ensemblpanpan1.1panPan2
SYMPK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11109,757,951 - 109,795,672 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1109,758,019 - 109,795,651 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1109,243,265 - 109,280,560 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01110,290,734 - 110,328,381 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1110,290,775 - 110,347,324 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11109,966,753 - 110,004,042 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01109,601,437 - 109,638,719 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01110,470,207 - 110,507,505 (+)NCBIUU_Cfam_GSD_1.0
Sympk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934917,814,691 - 17,848,307 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367062,158,608 - 2,195,640 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367062,161,933 - 2,195,586 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SYMPK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl652,138,204 - 52,199,220 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1652,135,580 - 52,180,382 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2647,402,855 - 47,443,678 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SYMPK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1639,264,850 - 39,308,912 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl639,264,802 - 39,308,812 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607318,902,163 - 18,950,907 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sympk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248327,354,272 - 7,394,255 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248327,351,303 - 7,394,337 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sympk
116 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:144
Count of miRNA genes:112
Interacting mature miRNAs:123
Transcripts:ENSRNOT00000019814
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15389511782174945Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)17219768090508767Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)177876254106047988Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14936146582174945Rat
61344Bp29Blood pressure QTL 297.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)178350581123350581Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)177494165122494165Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)15386304190532583Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)13483685879836858Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)15034351099980958Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)177857876122857876Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)178430536123430536Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)15389511782174945Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
61433Cia2Collagen induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)17843075491209302Rat

Markers in Region
RH126861  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2178,700,325 - 78,700,669 (+)MAPPERmRatBN7.2
Rnor_6.0179,959,103 - 79,959,446NCBIRnor6.0
Rnor_5.0181,218,916 - 81,219,259UniSTSRnor5.0
RGSC_v3.4178,407,223 - 78,407,566UniSTSRGSC3.4
Celera173,166,409 - 73,166,752UniSTS
Cytogenetic Map1q21UniSTS
AW529469  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2178,700,529 - 78,700,679 (+)MAPPERmRatBN7.2
Rnor_6.0179,959,307 - 79,959,456NCBIRnor6.0
Rnor_5.0181,219,120 - 81,219,269UniSTSRnor5.0
RGSC_v3.4178,407,427 - 78,407,576UniSTSRGSC3.4
Celera173,166,613 - 73,166,762UniSTS
RH 3.4 Map1818.9UniSTS
Cytogenetic Map1q21UniSTS
AI449890  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2178,700,232 - 78,700,338 (+)MAPPERmRatBN7.2
Rnor_6.0179,959,010 - 79,959,115NCBIRnor6.0
Rnor_5.0181,218,823 - 81,218,928UniSTSRnor5.0
RGSC_v3.4178,407,130 - 78,407,235UniSTSRGSC3.4
Celera173,166,316 - 73,166,421UniSTS
Cytogenetic Map1q21UniSTS
BF390442  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2178,697,583 - 78,697,772 (+)MAPPERmRatBN7.2
Rnor_6.0179,956,361 - 79,956,549NCBIRnor6.0
Rnor_5.0181,216,174 - 81,216,362UniSTSRnor5.0
RGSC_v3.4178,404,481 - 78,404,669UniSTSRGSC3.4
Celera173,163,667 - 73,163,855UniSTS
RH 3.4 Map1794.5UniSTS
Cytogenetic Map1q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000019814   ⟹   ENSRNOP00000019814
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl178,672,378 - 78,700,684 (+)Ensembl
Rnor_6.0 Ensembl179,931,156 - 79,959,461 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000084985   ⟹   ENSRNOP00000071808
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl178,672,389 - 78,700,678 (+)Ensembl
Rnor_6.0 Ensembl179,931,166 - 79,959,430 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000094104   ⟹   ENSRNOP00000096286
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl178,672,389 - 78,700,678 (+)Ensembl
RefSeq Acc Id: NM_001415786   ⟹   NP_001402715
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8187,800,416 - 87,828,727 (+)NCBI
mRatBN7.2178,672,372 - 78,700,684 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001402715 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH93391 (Get FASTA)   NCBI Sequence Viewer  
  EDM08243 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000019814.6
  ENSRNOP00000071808.1
  ENSRNOP00000096286.1
Ensembl Acc Id: ENSRNOP00000071808   ⟸   ENSRNOT00000084985
Ensembl Acc Id: ENSRNOP00000019814   ⟸   ENSRNOT00000019814
Ensembl Acc Id: ENSRNOP00000096286   ⟸   ENSRNOT00000094104
RefSeq Acc Id: NP_001402715   ⟸   NM_001415786
- UniProtKB: A0A0G2K1E5 (UniProtKB/TrEMBL)
Protein Domains
Symplekin C-terminal   Symplekin/Pta1 N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K1E5-F1-model_v2 AlphaFold A0A0G2K1E5 1-1280 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689756
Promoter ID:EPDNEW_R280
Type:initiation region
Name:Sympk_1
Description:symplekin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0179,931,150 - 79,931,210EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306735 AgrOrtholog
BioCyc Gene G2FUF-60542 BioCyc
Ensembl Genes ENSRNOG00000014353 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000019814.8 UniProtKB/TrEMBL
  ENSRNOT00000084985.2 UniProtKB/TrEMBL
  ENSRNOT00000094104.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7388361 IMAGE-MGC_LOAD
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Symplekin/Pta1 UniProtKB/TrEMBL
  Symplekin/Pta1_N UniProtKB/TrEMBL
  Symplekin_C UniProtKB/TrEMBL
MGC_CLONE MGC:112748 IMAGE-MGC_LOAD
NCBI Gene 292683 ENTREZGENE
PANTHER PTHR15245:SF20 UniProtKB/TrEMBL
  SYMPLEKIN-RELATED UniProtKB/TrEMBL
Pfam DUF3453 UniProtKB/TrEMBL
  Symplekin_C UniProtKB/TrEMBL
PhenoGen Sympk PhenoGen
RatGTEx ENSRNOG00000014353 RatGTEx
Superfamily-SCOP ARM-type_fold UniProtKB/TrEMBL
UniProt A0A0G2K1E5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ALH1_RAT UniProtKB/TrEMBL
  A6J8J1_RAT UniProtKB/TrEMBL
  F1LSH0_RAT UniProtKB/TrEMBL
  Q561R4_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-09-17 Sympk  symplekin scaffold protein  Sympk  symplekin  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Sympk  symplekin  Sympk_predicted  symplekin (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Sympk_predicted  symplekin (predicted)      Symbol and Name status set to approved 70820 APPROVED