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Gene: Adh6 (alcohol dehydrogenase 6 (class V)) Rattus norvegicus

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Symbol:

Adh6

Name:

alcohol dehydrogenase 6 (class V)

RGD ID:

1306313

Description:

Predicted to enable all-trans-retinol dehydrogenase (NAD+) activity and zinc ion binding activity. Predicted to be involved in retinoic acid metabolic process and retinol metabolic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Orthologous to human ADH6 (alcohol dehydrogenase 6 (class V)); PARTICIPATES IN fatty acid metabolic pathway; gluconeogenesis pathway; glycolysis pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 4,4'-diaminodiphenylmethane.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

alcohol dehydrogenase 6; class V alcohol dehydrogenase; LOC310903

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ADH6 (alcohol dehydrogenase 6 (class V))	HGNC	Ensembl, HomoloGene, Inparanoid, OrthoDB, Panther
Mus musculus (house mouse):	Adh6b (alcohol dehydrogenase 6B (class V))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ADH6 (alcohol dehydrogenase 6 (class V))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	LOC100856515 (alcohol dehydrogenase 1-like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LOC110261964 (alcohol dehydrogenase 6-like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ADH6 (alcohol dehydrogenase 6 (class V))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ADH6 (alcohol dehydrogenase 6 (class V))	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	adh8b (alcohol dehydrogenase 8b)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	adh8b (alcohol dehydrogenase 8b)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	zgc:77938	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	zgc:77938	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	zgc:63568	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	zgc:63568	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	adh8a (alcohol dehydrogenase 8a)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	adh8a (alcohol dehydrogenase 8a)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Fdh	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	H24K24.3	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	SFA1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	arhgdig	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	adh1c	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	adh1c	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	adh1b	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	adh7	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	adh7	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	adh1a	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	adh1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	adh6	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	LOC100487777	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	LOC100486839	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	LOC100488099	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	LOC100487777	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	LOC100488099	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	229,576,612 - 229,608,359 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	229,576,636 - 229,607,914 (+)	Ensembl				GRCr8
mRatBN7.2	2	226,903,208 - 226,934,564 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	226,903,250 - 226,934,534 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	234,650,831 - 234,713,541 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	232,550,567 - 232,613,268 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	227,415,250 - 227,477,952 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	243,656,568 - 243,687,857 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	243,550,627 - 243,687,857 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	262,193,252 - 262,224,625 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	235,907,340 - 235,938,846 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	219,059,887 - 219,091,198 (+)	NCBI		Celera
RGSC_v3.1	2	235,894,079 - 235,925,586 (+)	NCBI
Cytogenetic Map	2	q44	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autism spectrum disorder (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,3-dimethoxynaphthalene-1,4-dione (ISO)

3,3',4,4',5-pentachlorobiphenyl (ISO)

3-methylcholanthrene (ISO)

4,4'-diaminodiphenylmethane (EXP)

4-amino-2,6-dinitrotoluene (EXP)

aflatoxin B1 (EXP,ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

arsenous acid (ISO)

atazanavir sulfate (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (EXP,ISO)

butanal (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

chenodeoxycholic acid (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

cyhalothrin (EXP)

deoxycholic acid (ISO)

diarsenic trioxide (ISO)

endosulfan (ISO)

glycochenodeoxycholic acid (ISO)

glycocholic acid (ISO)

glycodeoxycholic acid (ISO)

hexanal (EXP)

isoniazide (ISO)

leflunomide (ISO)

Muraglitazar (EXP)

N-nitrosodiethylamine (ISO)

N-nitrosodimethylamine (ISO)

nefazodone (ISO)

O-methyleugenol (ISO)

ochratoxin A (EXP)

okadaic acid (ISO)

paracetamol (ISO)

pentanal (ISO)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP)

phenformin (EXP)

phenobarbital (ISO)

propanal (ISO)

quercetin (ISO)

rotenone (EXP)

silicon dioxide (ISO)

sodium arsenite (ISO)

Sunset Yellow FCF (ISO)

tartrazine (ISO)

Tesaglitazar (EXP)

tetrachloromethane (EXP)

thioacetamide (EXP)

trichloroethene (EXP)

urethane (ISO)

valproic acid (ISO)

zinc atom (ISO)

zinc(0) (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

retinoic acid metabolic process (IBA)

retinol metabolic process (IBA)

Cellular Component

cytoplasm (IEA)

cytosol (IBA)

Molecular Function

alcohol dehydrogenase (NAD+) activity (IEA,ISO)

all-trans-retinol dehydrogenase (NAD+) activity (IBA)

metal ion binding (IEA)

oxidoreductase activity (IEA)

zinc ion binding (IBA,IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

fatty acid metabolic pathway (IEA)

gluconeogenesis pathway (IEA)

glycolysis pathway (IEA)

glycolysis/gluconeogenesis pathway (IEA)

phase I biotransformation pathway via cytochrome P450 (IEA)

retinol metabolic pathway (IEA)

tyrosine metabolic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:9982	PMID:1755855	PMID:12477932	PMID:15489334	PMID:19056867	PMID:23376485

Genomics

Comparative Map Data

Adh6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	229,576,612 - 229,608,359 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	229,576,636 - 229,607,914 (+)	Ensembl				GRCr8
mRatBN7.2	2	226,903,208 - 226,934,564 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	226,903,250 - 226,934,534 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	234,650,831 - 234,713,541 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	232,550,567 - 232,613,268 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	227,415,250 - 227,477,952 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	243,656,568 - 243,687,857 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	243,550,627 - 243,687,857 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	262,193,252 - 262,224,625 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	235,907,340 - 235,938,846 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	219,059,887 - 219,091,198 (+)	NCBI		Celera
RGSC_v3.1	2	235,894,079 - 235,925,586 (+)	NCBI
Cytogenetic Map	2	q44	NCBI

ADH6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	99,202,639 - 99,219,246 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	99,202,436 - 99,219,537 (-)	Ensembl			hg38	GRCh38
GRCh37	4	100,123,796 - 100,140,403 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	100,342,818 - 100,359,426 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	4	100,483,056 - 100,497,579	NCBI
Celera	4	97,421,068 - 97,437,673 (-)	NCBI		Celera
Cytogenetic Map	4	q23	NCBI
HuRef	4	95,861,628 - 95,878,222 (-)	NCBI		HuRef
CHM1_1	4	100,100,226 - 100,116,832 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	4	102,517,454 - 102,534,061 (-)	NCBI		T2T-CHM13v2.0

Adh6b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	138,047,176 - 138,064,621 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	138,047,536 - 138,064,622 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	3	138,341,412 - 138,358,859 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	138,341,775 - 138,358,861 (+)	Ensembl			mm10	GRCm38
MGSCv37	3	138,007,024 - 138,058,017 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	3	138,280,246 - 138,296,247 (+)	NCBI		MGSCv36	mm8
Celera	3	144,748,453 - 144,766,508 (+)	NCBI		Celera
Cytogenetic Map	3	G3	NCBI
cM Map	3	64.21	NCBI

ADH6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	97,265,685 - 97,275,876 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	97,544,454 - 97,560,241 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	91,604,422 - 91,621,342 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	102,266,052 - 102,283,210 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	102,264,224 - 102,283,210 (-)	Ensembl			panPan2	panpan1.1

LOC100856515
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	32	21,383,276 - 21,397,237 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	32	20,533,206 - 20,547,149 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	32	21,569,512 - 21,583,534 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
UMICH_Zoey_3.1	32	21,547,156 - 21,561,148 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	32	21,361,716 - 21,375,665 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	32	18,519,779 - 18,533,782 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

LOC110261964
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	8	121,170,548 - 121,181,415 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

ADH6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	47,294,074 - 47,309,771 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	47,291,221 - 47,309,102 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666037	25,726,580 - 25,741,357 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in Adh6
289 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	164
Count of miRNA genes:	128
Interacting mature miRNAs:	133
Transcripts:	ENSRNOT00000036993
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331734	Bp204	Blood pressure QTL 204	3.61192		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	170656145	239614549	Rat
631563	Hcuc3	Hepatic copper content QTL 3	3.87		liver copper amount (VT:0003065)	liver copper weight to liver dry weight ratio (CMO:0001512)	2	212145502	231732847	Rat
631501	Bp101	Blood pressure QTL 101	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	205135267	250135267	Rat
1598813	Memor9	Memory QTL 9	2.7		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	2	202029709	236904960	Rat
2307174	Activ3	Activity QTL 3	4.83	0.000058	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	2	210956252	251712708	Rat
8693697	Alc36	Alcohol consumption QTL 36	2	0.592	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	2	219814164	239320906	Rat
1331794	Bp202	Blood pressure QTL 202	3.66819		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	143344967	251712708	Rat
1298075	Scl17	Serum cholesterol level QTL 17	3.4		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	2	214404877	251712708	Rat
1331805	Cm29	Cardiac mass QTL 29	3.50746		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	2	143344967	251712708	Rat
1354649	Kidm17	Kidney mass QTL 17	2.9		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	2	83465462	229820014	Rat
1300126	Bp175	Blood pressure QTL 175	3.46		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	204795005	249795005	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	20695736	231474293	Rat
7207484	Bss108	Bone structure and strength QTL 108	5.3		femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	2	214404877	251712708	Rat
2313073	Bmd75	Bone mineral density QTL 75	4.1	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	2	218051934	251712708	Rat
738013	Alc15	Alcohol consumption QTL 15	4.1	0.00022	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	2	186850607	231850607	Rat
61398	Bp50	Blood pressure QTL 50	4.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	192287802	237287802	Rat
7207482	Bss107	Bone structure and strength QTL 107	7		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	2	214404877	251712708	Rat
2317752	Glom23	Glomerulus QTL 23	3.6		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	2	196140964	251540988	Rat
61467	Bp14	Blood pressure QTL 14	2.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	205135267	250135267	Rat
1549836	Bss2	Bone structure and strength QTL 2	7.5		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	2	214404877	251712708	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	2	205135267	250135267	Rat
1359031	Bp275	Blood pressure QTL 275			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	188565047	233565047	Rat
1581499	Esta2	Estrogen-induced thymic atrophy QTL 2			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	2	192287802	229609668	Rat
1331767	Hrtrt12	Heart rate QTL 12	3.373		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	2	221088977	243501206	Rat
9589044	Scfw1	Subcutaneous fat weight QTL 1	5.8	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	2	184856304	229856304	Rat
8694435	Bw166	Body weight QTL 166	14.08	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	2	184856304	229856304	Rat
2293833	Kiddil8	Kidney dilation QTL 8	2.9		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	220274283	249795005	Rat
8694383	Bw158	Body weight QTL 158	7.69	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	2	184856304	229856304	Rat
1598835	Anxrr18	Anxiety related response QTL 18	2.98		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	2	203664411	248664411	Rat
7207490	Bss111	Bone structure and strength QTL 111	6.4		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	2	214404877	251712708	Rat
8693622	Alc26	Alcohol consumption QTL 26	2.4	0.667	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	2	223810546	243965570	Rat
2306901	Bp337	Blood pressure QTL 337		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	166372086	229820014	Rat
8694194	Abfw1	Abdominal fat weight QTL 1	11.7	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	2	184856304	229856304	Rat
61366	Iddm3	Insulin dependent diabetes mellitus QTL 3	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	192287802	237287802	Rat
2293844	Kiddil7	Kidney dilation QTL 7	3.5		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	220274283	249795005	Rat
1641891	Alcrsp17	Alcohol response QTL 17			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	151869660	251712708	Rat

Markers in Region

RH94448

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	226,804,370 - 226,804,497 (+)	MAPPER	mRatBN7.2
mRatBN7.2	2	226,925,460 - 226,925,587 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	243,678,784 - 243,678,910	NCBI	Rnor6.0
Rnor_6.0	2	243,557,722 - 243,557,848	NCBI	Rnor6.0
Rnor_5.0	2	262,215,552 - 262,215,678	UniSTS	Rnor5.0
Rnor_5.0	2	262,098,456 - 262,098,582	UniSTS	Rnor5.0
RGSC_v3.4	2	235,806,700 - 235,806,826	UniSTS	RGSC3.4
RGSC_v3.4	2	235,929,773 - 235,929,899	UniSTS	RGSC3.4
Celera	2	219,082,133 - 219,082,259	UniSTS
Celera	2	218,961,124 - 218,961,250	UniSTS
RH 3.4 Map	2	1605.6	UniSTS
Cytogenetic Map	2	q44	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
9	11	36	110	91	90	59	26	59	6	240	89	4	88	75	61	31	3	3

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001012084	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006233374	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008761507	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017590939	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039102468	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281975	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281976	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281977	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010063619	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC118967	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC140765	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC083792	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000036993 ⟹ ENSRNOP00000030638

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	229,576,636 - 229,607,914 (+)	Ensembl
mRatBN7.2 Ensembl	2	226,903,250 - 226,934,534 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000096969 ⟹ ENSRNOP00000084312

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	229,585,338 - 229,607,914 (+)	Ensembl
mRatBN7.2 Ensembl	2	226,911,958 - 226,934,534 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000106556 ⟹ ENSRNOP00000097057

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	229,585,008 - 229,607,914 (+)	Ensembl
mRatBN7.2 Ensembl	2	226,903,250 - 226,934,534 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000116824 ⟹ ENSRNOP00000078781

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	226,903,250 - 226,934,534 (+)	Ensembl

RefSeq Acc Id:

NM_001012084 ⟹ NP_001012084

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	229,576,636 - 229,607,914 (+)	NCBI
mRatBN7.2	2	226,903,256 - 226,934,534 (+)	NCBI
Rnor_6.0	2	243,656,579 - 243,687,857 (+)	NCBI
Rnor_5.0	2	262,193,252 - 262,224,625 (+)	NCBI
RGSC_v3.4	2	235,907,340 - 235,938,846 (+)	RGD
Celera	2	219,059,887 - 219,091,198 (+)	RGD

Sequence:

show sequence

GTGAAAGGCCAGAGTCAGAAGGACACTTCCAAAGCGAGCTTCCCAAGGAAAATGGGCACCCAGG
GAAAGGTGATCAGATGCAAAGCCACTGTGCTCTGGAAGCCTGGAGCCCCACTTGCCATTGAGGA
GATCGAAGTGGCCCCACCTAAAGCAAAGGAGGTTCGAATAAAGATGGTGGCCACAGGAGTCTGT
GGCACAGACATAAAACATCTGGACACACAAGAACTTTCTAAGTTTTGCCCCATGATTATGGGCC
ATGAAGGAGTTGGGATAGTCGAGAGTGTGGGGGAAGGAGTAAGCAGCGTAAGAACAGGTGATAA
AGTTATCCTATTATGTATCCCTCAGTGTGGGGAATGCAAAACTTGCCTGAATTCCAAGAACAAT
ATTTGTACAGAAATTAGACTGTCAAAGACACACCTGGCATCTGAAGGCACCAGCAGAATTACCT
GCAAGGGAAAGTTAGTGCATCAGTATATCGCTCTCGGCAGCTTCTCGGAATACACAGTCCTAAA
GGAAATCTCAGTCGCCAAGATTGACGAAGGTGCACCTCTGGAGAAGGTGTGCATAATTGGCTGT
GGGTTTGCCACTGGGTACGGCGCTGCCATCAACTCTGCCAAGGTGACCCCAGGCTCCACCTGTG
CGGTGTTTGGCCTCGGAGGTGTCGGTCTGTCTGTCATCATTGGCTGTAAAGCAGCAGGAGCAGC
CAGGATCATTGCCGTGGACATCAACAAAGACAGGTTTGCGAAGGCCAAGACAGTGGGTGCCACT
GACTGCGTCGACCCACGGGACTTCGAGAAACCCATTGAGGAAGTTTTATCCGATATGATAGATG
GTGGCGTGGACTTCTGCTTTGAGGTCACTGGGAACACAGAAGCAGTGGGAGCTGCCCTGGGCTC
CTGTCACAAGGACCACGGGGTCTGCGTGACTGTTGGAGCCCTAGCATCTTTCACCAGTACACTC
AGCATTAGAAGCCACTTGTTCTTCTCAGGACGCATTCTGAAAGGGTCTATTTTGGGAGGCTGGA
AAACGAAAGAAGAAATCCCTAAGCTGGTTTCTGACTATATGGCAAAGAAGTTTAACATAGATCC
TCTGATCACCCACACCCTGACTCTCAGCGAGGCCAATGAGGCAGTTCAGCTCATGAAAAGTGGG
CAATGTATCCGCTGTGTCCTGCTCCTATAACTACGAGATCTACATATGTCACCACGTGTCAAGA
TTTAGAAGAATCCACCACGCAATGCTTTTCTATTTTCTTGCCTTTCATTCACTCGGCAACAATC
TTTTATCAAGTTCTCACCTGTTCACACCATCGAAATCTTCCCCTGTGACCCAGTACCGTTGGAA
TACAGTCTCCCTTTTACAGCTGTGAGGGTCGATTTGAGTCGCCCAGTGGCAGAGTCCGCAGAGG
AGGGCACACCAAGATGCTCCAATGGCACGGAGGTCCCTACGTAGGGATGCACATTTCCTCACTC
ACTGAATCTTTCCCACGCTGTATGGATCCCACCAGAGAAGTTACTGGAACTGATAAACAAATGG
GCGAATGTTTAGGTCACAAAACCACCACCCCCAGAACCCACGGTGTGGTTGTATGGCAACAGCA
AGTTATCTCATATGGAGTCAAGGAGACAATCTCACAACTGCTGTGAGATTGATCTCGCAAATAA
ATTAACAACATAGAAATCAATTTAATCAAAGGTGAAATATCCCTACAATAAAAAGTATAAAACA
AGAGAGAAGCTGTGGCAGGACAATGGAGGCTCACATTAAGATTCCGCTTGAGGGGCTGGGGATG
TAGCTCAGTGGTAGAGCGCTTACCTAGGAAGCGCAAGGCCCTGGGTTCGGTCCCCAGCTCCG

hide sequence

RefSeq Acc Id:

XM_006233374 ⟹ XP_006233436

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	229,576,614 - 229,608,308 (+)	NCBI
mRatBN7.2	2	226,903,233 - 226,934,564 (+)	NCBI
Rnor_6.0	2	243,656,568 - 243,687,750 (+)	NCBI
Rnor_5.0	2	262,193,252 - 262,224,625 (+)	NCBI

Sequence:

show sequence

TCTGGGTAGAGGTGAAAGGCCAGAGTCAGAAGGACACTTCCAAAGCGAGCTTCCCAAGGAAAAT
GGGCACCCAGGGAAAGGGTCATGGGTCAAGGTCATAATAAAATGCTGATTCGTGAAATGATCAA
AATGGAACCTGGGGTGATCAGATGCAAAGCCACTGTGCTCTGGAAGCCTGGAGCCCCACTTGCC
ATTGAGGAGATCGAAGTGGCCCCACCTAAAGCAAAGGAGGTTCGAATAAAGATGGTGGCCACAG
GAGTCTGTGGCACAGACATAAAACATCTGGACACACAAGAACTTTCTAAGTTTTGCCCCATGAT
TATGGGCCATGAAGGAGTTGGGATAGTCGAGAGTGTGGGGGAAGGAGTAAGCAGCGTAAGAACA
GGTGATAAAGTTATCCTATTATGTATCCCTCAGTGTGGGGAATGCAAAACTTGCCTGAATTCCA
AGAACAATATTTGTACAGAAATTAGACTGTCAAAGACACACCTGGCATCTGAAGGCACCAGCAG
AATTACCTGCAAGGGAAAGTTAGTGCATCAGTATATCGCTCTCGGCAGCTTCTCGGAATACACA
GTCCTAAAGGAAATCTCAGTCGCCAAGATTGACGAAGGTGCACCTCTGGAGAAGGTGTGCATAA
TTGGCTGTGGGTTTGCCACTGGGTACGGCGCTGCCATCAACTCTGCCAAGGTGACCCCAGGCTC
CACCTGTGCGGTGTTTGGCCTCGGAGGTGTCGGTCTGTCTGTCATCATTGGCTGTAAAGCAGCA
GGAGCAGCCAGGATCATTGCCGTGGACATCAACAAAGACAGGTTTGCGAAGGCCAAGACAGTGG
GTGCCACTGACTGCGTCGACCCACGGGACTTCGAGAAACCCATTGAGGAAGTTTTATCCGATAT
GATAGATGGTGGCGTGGACTTCTGCTTTGAGGTCACTGGGAACACAGAAGCAGTGGGAGCTGCC
CTGGGCTCCTGTCACAAGGACCACGGGGTCTGCGTGACTGTTGGAGCCCTAGCATCTTTCACCA
GTACACTCAGCATTAGAAGCCACTTGTTCTTCTCAGGACGCATTCTGAAAGGGTCTATTTTGGG
AGGCTGGAAAACGAAAGAAGAAATCCCTAAGCTGGTTTCTGACTATATGGCAAAGAAGTTTAAC
ATAGATCCTCTGATCACCCACACCCTGACTCTCAGCGAGGCCAATGAGGCAGTTCAGCTCATGA
AAAGTGGGCAATGTATCCGCTGTGTCCTGCTCCTATAACTACGAGATCTACATATGTCACCACG
TGTCAAGATTTAGAAGAATCCACCACGCAATGCTTTTCTATTTTCTTGCCTTTCATTCACTCGG
CAACAATCTTTTATCAAGTTCTCACCTGTTCACACCATCGAAATCTTCCCCTGTGACCCAGTAC
CGTTGGAATACAGTCTCCCTTTTACAGCTGTGAGGGTCGATTTGAGTCGCCCAGTGGCAGAGTC
CGCAGAGGAGGGCACACCAAGATGCTCCAATGGCACGGAGGTCCCTACGTAGGGATGCACATTT
CCTCACTCACTGAATCTTTCCCACGCTGTATGGATCCCACCAGAGAAGTTACTGGAACTGATAA
ACAAATGGGCGAATGTTTAGGTCACAAAACCACCACCCCCAGAACCCACGGTGTGGTTGTATGG
CAACAGCAAGTTATCTCATATGGAGTCAAGGAGACAATCTCACAACTGCTGTGAGATTGATCTC
GCAAATAAATTAACAACATAGAAATCAATTTAATCAAAGGTGAAATATCCCTACAATAAAAAGT
ATAAAACAAGAGAGAAGCTGTGGCAGG

hide sequence

RefSeq Acc Id:

XM_017590939 ⟹ XP_017446428

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	229,576,636 - 229,608,308 (+)	NCBI
mRatBN7.2	2	226,911,143 - 226,934,564 (+)	NCBI
Rnor_6.0	2	243,660,125 - 243,687,750 (+)	NCBI

Sequence:

show sequence

AGGGCCCGACTATTTTTCTTTCTTTTGTCTTCAACTTTTGTCTAGGGGGCAAGTTCAAACTTTT
ACCTTTCGCATGTTTGCTGATAAAAGTAAACAGCCAAAGGCTATGTTGTCAAACTCAGGTTGAA
AAATTATTCAGGACACCCAAATGGTGGGTATCCCTGGACATTGTAACGCAATCCTATTTTAAAA
AATACACTTCTCTTTTAGATTACCAATGAGCTGCTGCCGCCTGCTTGTGATGTTAACAGCTAGC
ATCTGGGTTTCTCTCAAGTTTGGCCCATGCTAGCCACCTCCACTGGCCATCGTAGCTGGTCCAT
GGACTTAGGCATCTATTGCTGAAAGTGCACTAACCATGGGACAGTTACCTTGACTGACTTCTAC
ATTTCCAAGCGTCCACTCCCTGTGCAGAAGTCTGTGTAGCAAACAACTGATTACACAGTTACAC
TTTGATCTGGCAAATATGAGTTACATCAATCAAGGTGTAAAAAAGAAAATGTATCCTTCTACAG
GGTTCTAGAATGAAGGTTATGATATAGTGTCCAGACAGCCAGACAACTAAGTTTCAGGATACTA
AATATCTTATTAACTTGTGTTAATCATAATGTGGAAAAATCTTCCTCACTGACTGTCTCTTCCT
CATGAGGATACAGTAATAGAAACTCAGCAACTGACTTCTGAACGTAAATTGGCTGGTGAAAGGC
TCCTTGAACTCCTGAGCCAGACTAGTGGCTCCTCCACGATCTACATCTTCTGGTGAACAATGGT
GGCAACAAAATCACCAGTCTTGTCAAAAACTCACGAAACCTGCTGAGGAGTCTTAAAATGGCTT
TCTCACCTATTCTCTTTCTCTGATAAAGGCAAAGCTGCCCCGACTATTTTTCTAACTCCATTCT
CAGTAGAATCACTGAAATAAAAGTCTCGCTTGTCCTATGTTACAGGTGCTACTCAGGTGCATGG
TGCATTCCTAAAATACCTGCTACCACCAAACAGATGCTATGTTCTGAGTCTTAGCCATCACCTA
AGCATTACCTTGGCCTCTTAGATTGATGCCTCTCTGAGGAAATCTGGCTACTGCCCCTTCTGCA
TCAACCATATCATTAGCTCAAAACAGTTAAGAGTGGTCTGCACCCCCAAATCCCTACAGTACTT
CACATCCCAACTGCAGTTTCCCCTCCCTCCTCTCTCTCTACTCTCCTCCTTCCAACACCCGCGC
CCCAATCCACTCCTCCCTGTCTCTTCAGAAGAGTGAAGGCTGCTCATGGATATCAACTAGCTTT
GGCATAAAAAGTTGTAGTAAGACTAGGTGCATCTTCTCCTATTGAGGCTAGTCACCCCACTAGA
GGGAAAGGGTCCCCAAAGGCAGGCAATAGAATAAGAGACAGCCCATGTTCTTACTGTTAGGAGT
TCCAAATCAACACCAAGCTACACAGCTGTTACATATGTGCTGGTGGCATATTGTTGATTGTTAG
CCAATGGTCTTAACCACTGAACTATCTCCAACCCAGGAATTTTCTTAACATACCACGGTGAATA
AAACTGAAAATGGCCATCAACATATGTGTGACACCATTAAATCCACACTAAATTAGGTCTTTAC
CAAACTAGGTCAGCACGTCAGAAAAGTAAAGTTGCACATCAATAATTCCAGATCATACTTCATG
ACCCAGAAATAGAAGAGTAGAATAAGACCAAGGCAAGGAGAAGGGAGAGGAAGCAGGAGAGGTA
ACAGCAGAGGCTAACACACTTAAAAACAGCAAGTGATCGAGAACATGAATAAAACAATGAGAAG
GTTCTTAAAAGAACGCACTTAACAAAGCTCTGGTAAGCTTGAAAGGAGACCATCCTGGGTAAGG
AAGGGAGATGTTCAACTTCACATTTTGTGTTCTTTCCCTGGGTAAACCTACCATATACGGTCAT
AAGAACCTCCCACAGGCAACAAGAAATGTATACATTTACAGGGATTTGAAAAAAACCGGTTAAT
AGTTATCTGACTTGAATAATTTTAGTAATAAGCAATAAGAAAGTATTCATTTACAGGGATTTGA
AAGAAACTGGTTAATAGTTATCTGACTTGAATAATCTTGATAATTATTTGACAGTCCTTTTTCC
CATTAATTCATTCATTTATTCACTTTACATCCAGATTGCAGCTCCCTCCTGCTGGTACACCCCC
ACATGAACCTTCCCCAACCCCCCCTTCCCTTCATTCTGAGAAGGGGGTGGTCCACCCTAGGTAC
CAACTCACCCTAGCACCTCAAGCCACTGCAGAACTAGGCACATGTTCTCCCACTGAGGCCAGAC
AAGACGGCCCAGTTAGGGGAACAGGATCCATGGGCAGGCAACAGAGTCCAGGGTCATGGGTCAA
GGTCATAATAAAATGCTGATTCGTGAAATGATCAAAATGGAACCTGGGCAGATCACAGCGCTGT
CAGCTTGCATTCATCACTGACTCCGAGTCATTTTTCCACCGCTCCCAAACACCCGTCCTCAGGA
CCCTCTTGCAAGATGAGGCTGGCACAAGGCGTAATACCACAACTCTGAAGTAACTAGTGGTCTA
TTTCATTCCTAATAATAGCACATACATTGTGAGGATGGGTGGCAGGGGCCTACAATGGCAGCCC
AGAGATGCGGAGGCAGGACGATCACAAGTTCAAAAGCAGACTGGCCTACAGAACAAGACAGTTT
CAGCAGAGAGAGAAAGCTATCCGTCCATTTATATGTGTGCTTTCCTATAAATATAAACGACATT
TGCTACACTGACTTGAATATAGAAGCTGAAAGCAGAACAAAAACAATACACTGGGGTGGGAGCC
ACCACCTTCAGTATAGATGTAGACTTTTTCCTTTTTTTCCTCTTGAGTATGGGTGAATTAAGTG
CTTTCTGGTAATGATTGATGTAAGAGTCTTCCTAAACTTACTCACATCCCTGTCCCTCTTCATT
TGCTGTACCCAGGTGATCAGATGCAAAGCCACTGTGCTCTGGAAGCCTGGAGCCCCACTTGCCA
TTGAGGAGATCGAAGTGGCCCCACCTAAAGCAAAGGAGGTTCGAATAAAGATGGTGGCCACAGG
AGTCTGTGGCACAGACATAAAACATCTGGACACACAAGAACTTTCTAAGTTTTGCCCCATGATT
ATGGGCCATGAAGGAGTTGGGATAGTCGAGAGTGTGGGGGAAGGAGTAAGCAGCGTAAGAACAG
GTGATAAAGTTATCCTATTATGTATCCCTCAGTGTGGGGAATGCAAAACTTGCCTGAATTCCAA
GAACAATATTTGTACAGAAATTAGACTGTCAAAGACACACCTGGCATCTGAAGGCACCAGCAGA
ATTACCTGCAAGGGAAAGTTAGTGCATCAGTATATCGCTCTCGGCAGCTTCTCGGAATACACAG
TCCTAAAGGAAATCTCAGTCGCCAAGATTGACGAAGGTGCACCTCTGGAGAAGGTGTGCATAAT
TGGCTGTGGGTTTGCCACTGGGTACGGCGCTGCCATCAACTCTGCCAAGGTGACCCCAGGCTCC
ACCTGTGCGGTGTTTGGCCTCGGAGGTGTCGGTCTGTCTGTCATCATTGGCTGTAAAGCAGCAG
GAGCAGCCAGGATCATTGCCGTGGACATCAACAAAGACAGGTTTGCGAAGGCCAAGACAGTGGG
TGCCACTGACTGCGTCGACCCACGGGACTTCGAGAAACCCATTGAGGAAGTTTTATCCGATATG
ATAGATGGTGGCGTGGACTTCTGCTTTGAGGTCACTGGGAACACAGAAGCAGTGGGAGCTGCCC
TGGGCTCCTGTCACAAGGACCACGGGGTCTGCGTGACTGTTGGAGCCCTAGCATCTTTCACCAG
TACACTCAGCATTAGAAGCCACTTGTTCTTCTCAGGACGCATTCTGAAAGGGTCTATTTTGGGA
GGCTGGAAAACGAAAGAAGAAATCCCTAAGCTGGTTTCTGACTATATGGCAAAGAAGTTTAACA
TAGATCCTCTGATCACCCACACCCTGACTCTCAGCGAGGCCAATGAGGCAGTTCAGCTCATGAA
AAGTGGGCAATGTATCCGCTGTGTCCTGCTCCTATAACTACGAGATCTACATATGTCACCACGT
GTCAAGATTTAGAAGAATCCACCACGCAATGCTTTTCTATTTTCTTGCCTTTCATTCACTCGGC
AACAATCTTTTATCAAGTTCTCACCTGTTCACACCATCGAAATCTTCCCCTGTGACCCAGTACC
GTTGGAATACAGTCTCCCTTTTACAGCTGTGAGGGTCGATTTGAGTCGCCCAGTGGCAGAGTCC
GCAGAGGAGGGCACACCAAGATGCTCCAATGGCACGGAGGTCCCTACGTAGGGATGCACATTTC
CTCACTCACTGAATCTTTCCCACGCTGTATGGATCCCACCAGAGAAGTTACTGGAACTGATAAA
CAAATGGGCGAATGTTTAGGTCACAAAACCACCACCCCCAGAACCCACGGTGTGGTTGTATGGC
AACAGCAAGTTATCTCATATGGAGTCAAGGAGACAATCTCACAACTGCTGTGAGATTGATCTCG
CAAATAAATTAACAACATAGAAATCAATTTAATCAAAGGTGAAATATCCCTACAATAAAAAGTA
TAAAACAAGAGAGAAGCTGTGGCAGG

hide sequence

RefSeq Acc Id:

XM_039102468 ⟹ XP_038958396

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	229,576,636 - 229,608,308 (+)	NCBI
mRatBN7.2	2	226,903,267 - 226,934,564 (+)	NCBI

RefSeq Acc Id:

XM_063281974 ⟹ XP_063138044

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	229,576,614 - 229,608,311 (+)	NCBI

RefSeq Acc Id:

XM_063281975 ⟹ XP_063138045

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	229,576,614 - 229,608,308 (+)	NCBI

RefSeq Acc Id:

XM_063281976 ⟹ XP_063138046

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	229,576,614 - 229,608,308 (+)	NCBI

RefSeq Acc Id:

XM_063281977 ⟹ XP_063138047

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	229,576,615 - 229,608,307 (+)	NCBI

RefSeq Acc Id:

XR_010063619

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	229,576,612 - 229,608,359 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001012084	(Get FASTA)	NCBI Sequence Viewer
	XP_006233436	(Get FASTA)	NCBI Sequence Viewer
	XP_017446428	(Get FASTA)	NCBI Sequence Viewer
	XP_038958396	(Get FASTA)	NCBI Sequence Viewer
	XP_063138044	(Get FASTA)	NCBI Sequence Viewer
	XP_063138045	(Get FASTA)	NCBI Sequence Viewer
	XP_063138046	(Get FASTA)	NCBI Sequence Viewer
	XP_063138047	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH83792	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000030638
	ENSRNOP00000097057
GenBank Protein	Q5XI95	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001012084 ⟸ NM_001012084

- UniProtKB:

Q5XI95 (UniProtKB/Swiss-Prot), A0A8I6A108 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGTQGKVIRCKATVLWKPGAPLAIEEIEVAPPKAKEVRIKMVATGVCGTDIKHLDTQELSKFCP
MIMGHEGVGIVESVGEGVSSVRTGDKVILLCIPQCGECKTCLNSKNNICTEIRLSKTHLASEGT
SRITCKGKLVHQYIALGSFSEYTVLKEISVAKIDEGAPLEKVCIIGCGFATGYGAAINSAKVTP
GSTCAVFGLGGVGLSVIIGCKAAGAARIIAVDINKDRFAKAKTVGATDCVDPRDFEKPIEEVLS
DMIDGGVDFCFEVTGNTEAVGAALGSCHKDHGVCVTVGALASFTSTLSIRSHLFFSGRILKGSI
LGGWKTKEEIPKLVSDYMAKKFNIDPLITHTLTLSEANEAVQLMKSGQCIRCVLLL

hide sequence

RefSeq Acc Id:	XP_006233436 ⟸ XM_006233374
- Peptide Label:	isoform X3
- UniProtKB:	A0A8L2QGL3 (UniProtKB/TrEMBL), A0A8I6A108 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGQGHNKMLIREMIKMEPGVIRCKATVLWKPGAPLAIEEIEVAPPKAKEVRIKMVATGVCGTDI KHLDTQELSKFCPMIMGHEGVGIVESVGEGVSSVRTGDKVILLCIPQCGECKTCLNSKNNICTE IRLSKTHLASEGTSRITCKGKLVHQYIALGSFSEYTVLKEISVAKIDEGAPLEKVCIIGCGFAT GYGAAINSAKVTPGSTCAVFGLGGVGLSVIIGCKAAGAARIIAVDINKDRFAKAKTVGATDCVD PRDFEKPIEEVLSDMIDGGVDFCFEVTGNTEAVGAALGSCHKDHGVCVTVGALASFTSTLSIRS HLFFSGRILKGSILGGWKTKEEIPKLVSDYMAKKFNIDPLITHTLTLSEANEAVQLMKSGQCIR CVLLL hide sequence

RefSeq Acc Id:	XP_017446428 ⟸ XM_017590939
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I5ZLG2 (UniProtKB/TrEMBL), A0A8I6A108 (UniProtKB/TrEMBL)
- Sequence:	show sequence MIDVRVFLNLLTSLSLFICCTQVIRCKATVLWKPGAPLAIEEIEVAPPKAKEVRIKMVATGVCG TDIKHLDTQELSKFCPMIMGHEGVGIVESVGEGVSSVRTGDKVILLCIPQCGECKTCLNSKNNI CTEIRLSKTHLASEGTSRITCKGKLVHQYIALGSFSEYTVLKEISVAKIDEGAPLEKVCIIGCG FATGYGAAINSAKVTPGSTCAVFGLGGVGLSVIIGCKAAGAARIIAVDINKDRFAKAKTVGATD CVDPRDFEKPIEEVLSDMIDGGVDFCFEVTGNTEAVGAALGSCHKDHGVCVTVGALASFTSTLS IRSHLFFSGRILKGSILGGWKTKEEIPKLVSDYMAKKFNIDPLITHTLTLSEANEAVQLMKSGQ CIRCVLLL hide sequence

RefSeq Acc Id:	XP_038958396 ⟸ XM_039102468
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I5ZLG2 (UniProtKB/TrEMBL), A0A8I6A108 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000097057 ⟸ ENSRNOT00000106556

Ensembl Acc Id:

ENSRNOP00000030638 ⟸ ENSRNOT00000036993

Ensembl Acc Id:

ENSRNOP00000084312 ⟸ ENSRNOT00000096969

Ensembl Acc Id:

ENSRNOP00000078781 ⟸ ENSRNOT00000116824

RefSeq Acc Id:	XP_063138044 ⟸ XM_063281974
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6A108 (UniProtKB/TrEMBL), A0A8I6ATS6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063138046 ⟸ XM_063281976
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6A108 (UniProtKB/TrEMBL), A0A8I5ZLG2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063138045 ⟸ XM_063281975
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6A108 (UniProtKB/TrEMBL), A0A8I5ZLG2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063138047 ⟸ XM_063281977
- Peptide Label:	isoform X4
- UniProtKB:	A0A8I6A108 (UniProtKB/TrEMBL)

Protein Domains

Alcohol dehydrogenase-like C-terminal Alcohol dehydrogenase-like N-terminal Enoyl reductase (ER)

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5XI95-F1-model_v2	AlphaFold	Q5XI95	1-376	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306313	AgrOrtholog
BioCyc Gene	G2FUF-51068	BioCyc
Ensembl Genes	ENSRNOG00000012436	Ensembl
	ENSRNOG00000069176	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000036993	ENTREZGENE
	ENSRNOT00000106556	ENTREZGENE
Gene3D-CATH	Medium-chain alcohol dehydrogenases, catalytic domain	UniProtKB/Swiss-Prot
	NAD(P)-binding Rossmann-like Domain	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7106499	IMAGE-MGC_LOAD
InterPro	ADH_C	UniProtKB/Swiss-Prot
	ADH_N	UniProtKB/Swiss-Prot
	ADH_Zn_CS	UniProtKB/Swiss-Prot
	GroES-like_sf	UniProtKB/Swiss-Prot
	NAD(P)-bd_dom_sf	UniProtKB/Swiss-Prot
	PKS_ER	UniProtKB/Swiss-Prot
KEGG Report	rno:310903	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:94781	IMAGE-MGC_LOAD
NCBI Gene	310903	ENTREZGENE
PANTHER	ALCOHOL DEHYDROGENASE	UniProtKB/Swiss-Prot
	PTHR43880:SF20	UniProtKB/Swiss-Prot
Pfam	ADH_N	UniProtKB/Swiss-Prot
	ADH_zinc_N	UniProtKB/Swiss-Prot
PhenoGen	Adh6	PhenoGen
PROSITE	ADH_ZINC	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000012436	RatGTEx
	ENSRNOG00000069176	RatGTEx
SMART	PKS_ER	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF50129	UniProtKB/Swiss-Prot
	SSF51735	UniProtKB/Swiss-Prot
UniProt	A0A8I5ZLG2	ENTREZGENE
	A0A8I6A108	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6ATS6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8L2QGL3	ENTREZGENE
	A0A8L2R817_RAT	UniProtKB/TrEMBL
	ADH6_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-12-06	Adh6	alcohol dehydrogenase 6 (class V)	Adh6_predicted	alcohol dehydrogenase 6 (class V) (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Adh6_predicted	alcohol dehydrogenase 6 (class V) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)