Ppp2r5e (protein phosphatase 2 regulatory subunit B', epsilon) - Rat Genome Database

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Gene: Ppp2r5e (protein phosphatase 2 regulatory subunit B', epsilon) Rattus norvegicus
Analyze
Symbol: Ppp2r5e
Name: protein phosphatase 2 regulatory subunit B', epsilon
RGD ID: 1305657
Description: Predicted to enable protein phosphatase activator activity. Predicted to be involved in signal transduction. Predicted to be located in sperm midpiece and sperm principal piece. Predicted to be part of protein phosphatase type 2A complex. Predicted to be active in cytosol and nucleus. Biomarker of transient cerebral ischemia. Orthologous to human PPP2R5E (protein phosphatase 2 regulatory subunit B'epsilon); PARTICIPATES IN mRNA decay pathway; Wnt signaling pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC299147; protein phosphatase 2, regulatory subunit B (B56), epsilon isoform; protein phosphatase 2, regulatory subunit B', epsilon isoform; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8699,904,569 - 100,053,672 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl699,904,569 - 100,053,573 (-)EnsemblGRCr8
mRatBN7.2694,168,846 - 94,317,872 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl694,168,846 - 94,317,872 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx694,561,718 - 94,711,228 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0694,860,234 - 95,009,753 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0694,289,097 - 94,438,615 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd6101,448,044 - 101,597,605 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive6100,854,924 - 101,004,491 (-)NCBILyon_Normotensive
Lyon_Hypertensive698,648,716 - 98,798,287 (-)NCBILyon_Hypertensive
F344_StmMcwi697,796,580 - 97,945,842 (-)NCBIF344_StmMcwi
Rnor_6.0698,417,974 - 98,567,016 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl698,417,974 - 98,566,966 (-)Ensemblrn6Rnor6.0
Rnor_5.06107,836,104 - 107,985,250 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4698,047,316 - 98,197,549 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera692,596,832 - 92,745,242 (-)NCBICelera
RGSC_v3.1698,053,853 - 98,201,066 (-)NCBI
Cytogenetic Map6q24NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-sulfonyldiphenol  (ISO)
Aflatoxin B2 alpha  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
camptothecin  (ISO)
carbon nanotube  (ISO)
choline  (ISO)
ciguatoxin CTX1B  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (EXP)
diarsenic trioxide  (ISO)
dimethylarsinous acid  (ISO)
disodium selenite  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
Echimidine  (ISO)
elemental selenium  (ISO)
fenthion  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
glafenine  (EXP)
gold atom  (ISO)
gold(0)  (ISO)
inulin  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
methapyrilene  (EXP,ISO)
methidathion  (ISO)
methoxychlor  (EXP)
mitomycin C  (ISO)
monocrotaline  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
nefazodone  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenite  (ISO)
tamoxifen  (ISO)
taurine  (ISO)
titanium dioxide  (ISO)
toluene  (EXP)
topotecan  (EXP)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Proteomic Analysis of Hydroxysafflor Yellow A Against Cerebral Ischemia/Reperfusion Injury in Rats. Xu H, etal., Rejuvenation Res. 2019 Dec;22(6):503-512. doi: 10.1089/rej.2018.2145. Epub 2019 Mar 19.

Genomics

Comparative Map Data
Ppp2r5e
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8699,904,569 - 100,053,672 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl699,904,569 - 100,053,573 (-)EnsemblGRCr8
mRatBN7.2694,168,846 - 94,317,872 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl694,168,846 - 94,317,872 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx694,561,718 - 94,711,228 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0694,860,234 - 95,009,753 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0694,289,097 - 94,438,615 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd6101,448,044 - 101,597,605 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive6100,854,924 - 101,004,491 (-)NCBILyon_Normotensive
Lyon_Hypertensive698,648,716 - 98,798,287 (-)NCBILyon_Hypertensive
F344_StmMcwi697,796,580 - 97,945,842 (-)NCBIF344_StmMcwi
Rnor_6.0698,417,974 - 98,567,016 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl698,417,974 - 98,566,966 (-)Ensemblrn6Rnor6.0
Rnor_5.06107,836,104 - 107,985,250 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4698,047,316 - 98,197,549 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera692,596,832 - 92,745,242 (-)NCBICelera
RGSC_v3.1698,053,853 - 98,201,066 (-)NCBI
Cytogenetic Map6q24NCBI
PPP2R5E
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381463,371,364 - 63,543,377 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1463,371,364 - 63,543,410 (-)Ensemblhg38GRCh38
GRCh371463,838,082 - 64,010,095 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361462,911,108 - 63,079,832 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341462,911,107 - 63,079,832NCBI
Celera1443,892,051 - 44,060,782 (-)NCBICelera
Cytogenetic Map14q23.2NCBI
HuRef1444,007,943 - 44,177,149 (-)NCBIHuRef
CHM1_11463,780,369 - 63,949,091 (-)NCBICHM1_1
T2T-CHM13v2.01457,578,735 - 57,750,775 (-)NCBIT2T-CHM13v2.0
Ppp2r5e
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391275,496,237 - 75,643,064 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1275,497,655 - 75,643,019 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381275,449,463 - 75,596,237 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1275,450,881 - 75,596,245 (-)Ensemblmm10GRCm38
MGSCv371276,551,868 - 76,697,187 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361276,369,721 - 76,515,040 (-)NCBIMGSCv36mm8
Celera1276,535,179 - 76,696,642 (-)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1232.75NCBI
Ppp2r5e
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554666,263,338 - 6,420,685 (+)Ensembl
ChiLan1.0NW_0049554666,263,338 - 6,420,685 (+)NCBIChiLan1.0ChiLan1.0
PPP2R5E
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21564,477,774 - 64,648,588 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11463,694,290 - 63,865,548 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01443,947,793 - 44,119,020 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11462,207,182 - 62,373,711 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1462,207,192 - 62,373,711 (-)EnsemblpanPan2panpan1.1
PPP2R5E
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1837,945,350 - 38,088,322 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl837,945,331 - 38,088,110 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha837,663,916 - 37,780,994 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0838,172,395 - 38,314,626 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl838,172,672 - 38,314,720 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1837,789,055 - 37,931,745 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0837,868,630 - 38,004,310 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0838,221,858 - 38,364,575 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ppp2r5e
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864066,818,311 - 66,961,292 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364957,230,786 - 7,372,556 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364957,230,405 - 7,372,525 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP2R5E
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1194,505,025 - 194,656,164 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11194,505,535 - 194,653,302 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21216,594,665 - 216,628,082 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPP2R5E
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12440,548,986 - 40,730,451 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2440,553,635 - 40,633,392 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605328,759,264 - 28,930,715 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppp2r5e
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473437,510,255 - 37,675,482 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473437,509,711 - 37,678,807 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ppp2r5e
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1789,616,683 - 89,765,223 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ppp2r5e
3653 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:1082
Count of miRNA genes:343
Interacting mature miRNAs:481
Transcripts:ENSRNOT00000006755
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)671278722116278722Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)664367996109367996Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)688019181136741135Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)693560258136550638Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)690871046135871046Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)698944780143944780Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)679198463144254945Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)693778632138778632Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)686867923110125012Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)686867923110125012Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)684490437129490437Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)690871046135871046Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)693560258136550638Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)678204640123204640Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)693560258136550638Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)676937178121937178Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)699437079125323237Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)686494122112380234Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)699708426112483760Rat

Markers in Region
RH132173  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2694,172,155 - 94,172,341 (+)MAPPERmRatBN7.2
Rnor_6.0698,421,283 - 98,421,468NCBIRnor6.0
Rnor_5.06107,839,413 - 107,839,598UniSTSRnor5.0
RGSC_v3.4698,050,625 - 98,050,810UniSTSRGSC3.4
Celera692,600,141 - 92,600,326UniSTS
RH 3.4 Map6668.9UniSTS
Cytogenetic Map6q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000006755   ⟹   ENSRNOP00000006755
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl699,904,569 - 100,053,573 (-)Ensembl
mRatBN7.2 Ensembl694,168,846 - 94,317,872 (-)Ensembl
Rnor_6.0 Ensembl698,417,974 - 98,566,966 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000077715   ⟹   ENSRNOP00000068628
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl699,913,743 - 100,053,573 (-)Ensembl
mRatBN7.2 Ensembl694,178,021 - 94,317,872 (-)Ensembl
Rnor_6.0 Ensembl698,422,300 - 98,566,523 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094518   ⟹   ENSRNOP00000079138
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl699,904,569 - 100,053,573 (-)Ensembl
mRatBN7.2 Ensembl694,168,846 - 94,317,872 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105642   ⟹   ENSRNOP00000089462
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl699,904,569 - 100,005,107 (-)Ensembl
mRatBN7.2 Ensembl694,168,846 - 94,269,697 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112533   ⟹   ENSRNOP00000097176
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl699,904,569 - 100,053,573 (-)Ensembl
mRatBN7.2 Ensembl694,168,846 - 94,317,872 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000148403   ⟹   ENSRNOP00000099011
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl699,907,082 - 100,053,573 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000173031   ⟹   ENSRNOP00000099221
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl699,904,569 - 100,005,196 (-)Ensembl
RefSeq Acc Id: NM_001106740   ⟹   NP_001100210
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8699,904,569 - 100,053,573 (-)NCBI
mRatBN7.2694,168,846 - 94,317,872 (-)NCBI
Dahl_SR_JrHsd6101,448,044 - 101,597,563 (-)NCBI
Lyon_Normotensive6100,854,924 - 101,004,449 (-)NCBI
Lyon_Hypertensive698,648,716 - 98,798,245 (-)NCBI
F344_StmMcwi697,796,580 - 97,945,800 (-)NCBI
Rnor_6.0698,417,974 - 98,566,966 (-)NCBI
Rnor_5.06107,836,104 - 107,985,250 (-)NCBI
RGSC_v3.4698,047,316 - 98,197,549 (-)RGD
Celera692,596,832 - 92,745,242 (-)RGD
Sequence:
RefSeq Acc Id: NM_001434268   ⟹   NP_001421197
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Dahl_SR_JrHsd6101,451,151 - 101,597,605 (-)NCBI
Lyon_Normotensive6100,858,031 - 101,004,491 (-)NCBI
Lyon_Hypertensive698,651,823 - 98,798,287 (-)NCBI
F344_StmMcwi697,799,680 - 97,945,842 (-)NCBI
RefSeq Acc Id: NM_001434269   ⟹   NP_001421198
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Dahl_SR_JrHsd6101,451,151 - 101,597,605 (-)NCBI
Lyon_Normotensive6100,858,031 - 101,004,491 (-)NCBI
Lyon_Hypertensive698,651,823 - 98,798,287 (-)NCBI
F344_StmMcwi697,799,680 - 97,945,842 (-)NCBI
RefSeq Acc Id: NR_197772
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Dahl_SR_JrHsd6101,451,154 - 101,597,605 (-)NCBI
Lyon_Normotensive6100,858,034 - 101,004,491 (-)NCBI
Lyon_Hypertensive698,651,826 - 98,798,287 (-)NCBI
F344_StmMcwi697,799,683 - 97,945,842 (-)NCBI
RefSeq Acc Id: XM_006240222   ⟹   XP_006240284
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8699,907,678 - 100,053,672 (-)NCBI
mRatBN7.2694,169,395 - 94,317,478 (-)NCBI
Rnor_6.0698,418,523 - 98,567,016 (-)NCBI
Rnor_5.06107,836,104 - 107,985,250 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240223   ⟹   XP_006240285
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8699,907,678 - 100,053,652 (-)NCBI
mRatBN7.2694,169,395 - 94,317,477 (-)NCBI
Rnor_6.0698,418,523 - 98,567,016 (-)NCBI
Rnor_5.06107,836,104 - 107,985,250 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240224   ⟹   XP_006240286
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8699,907,678 - 100,032,670 (-)NCBI
mRatBN7.2694,169,395 - 94,271,661 (-)NCBI
Rnor_6.0698,418,523 - 98,518,780 (-)NCBI
Rnor_5.06107,836,104 - 107,985,250 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039112010   ⟹   XP_038967938
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8699,907,678 - 99,980,985 (-)NCBI
mRatBN7.2694,169,395 - 94,245,288 (-)NCBI
RefSeq Acc Id: NP_001100210   ⟸   NM_001106740
- UniProtKB: D3ZHI9 (UniProtKB/TrEMBL),   A6HC79 (UniProtKB/TrEMBL),   A0A0G2JTA1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240285   ⟸   XM_006240223
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006240284   ⟸   XM_006240222
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006240286   ⟸   XM_006240224
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JTA1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000006755   ⟸   ENSRNOT00000006755
Ensembl Acc Id: ENSRNOP00000068628   ⟸   ENSRNOT00000077715
RefSeq Acc Id: XP_038967938   ⟸   XM_039112010
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A9W8 (UniProtKB/TrEMBL),   A0A0G2JTA1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000079138   ⟸   ENSRNOT00000094518
Ensembl Acc Id: ENSRNOP00000089462   ⟸   ENSRNOT00000105642
Ensembl Acc Id: ENSRNOP00000097176   ⟸   ENSRNOT00000112533
Ensembl Acc Id: ENSRNOP00000099011   ⟸   ENSRNOT00000148403
Ensembl Acc Id: ENSRNOP00000099221   ⟸   ENSRNOT00000173031
RefSeq Acc Id: NP_001421198   ⟸   NM_001434269
RefSeq Acc Id: NP_001421197   ⟸   NM_001434268

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JTA1-F1-model_v2 AlphaFold A0A0G2JTA1 1-467 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694672
Promoter ID:EPDNEW_R5195
Type:initiation region
Name:Ppp2r5e_1
Description:protein phosphatase 2 regulatory subunit B', epsilon
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0698,567,008 - 98,567,068EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305657 AgrOrtholog
BioCyc Gene G2FUF-37081 BioCyc
Ensembl Genes ENSRNOG00000005045 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006755 ENTREZGENE
  ENSRNOT00000006755.8 UniProtKB/TrEMBL
  ENSRNOT00000077715.3 UniProtKB/TrEMBL
  ENSRNOT00000094518 ENTREZGENE
  ENSRNOT00000094518.2 UniProtKB/TrEMBL
  ENSRNOT00000105642 ENTREZGENE
  ENSRNOT00000105642.2 UniProtKB/TrEMBL
  ENSRNOT00000112533.2 UniProtKB/TrEMBL
  ENSRNOT00000148403.1 UniProtKB/TrEMBL
  ENSRNOT00000173031 ENTREZGENE
  ENSRNOT00000173031.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  PP2A_B56 UniProtKB/TrEMBL
KEGG Report rno:299147 UniProtKB/TrEMBL
NCBI Gene 299147 ENTREZGENE
PANTHER B56 UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT EPSILON ISOFORM UniProtKB/TrEMBL
Pfam B56 UniProtKB/TrEMBL
PhenoGen Ppp2r5e PhenoGen
PIRSF PP2A_B56 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005045 RatGTEx
Superfamily-SCOP ARM-type_fold UniProtKB/TrEMBL
UniProt A0A0G2JTA1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZMG6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A9W8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GLY3_RAT UniProtKB/TrEMBL
  A0ABK0L4R8_RAT UniProtKB/TrEMBL
  A0ABK0LBC2_RAT UniProtKB/TrEMBL
  A6HC79 ENTREZGENE, UniProtKB/TrEMBL
  D3ZHI9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-30 Ppp2r5e  protein phosphatase 2 regulatory subunit B', epsilon  Ppp2r5e  protein phosphatase 2, regulatory subunit B', epsilon isoform  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-12-15 Ppp2r5e  protein phosphatase 2, regulatory subunit B', epsilon isoform  Ppp2r5e  protein phosphatase 2, regulatory subunit B (B56), epsilon isoform   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Ppp2r5e  protein phosphatase 2, regulatory subunit B (B56), epsilon isoform   Ppp2r5e_predicted  protein phosphatase 2, regulatory subunit B (B56), epsilon isoform (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Ppp2r5e_predicted  protein phosphatase 2, regulatory subunit B (B56), epsilon isoform (predicted)      Symbol and Name status set to approved 70820 APPROVED