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Gene: Iqca1 (IQ motif containing with AAA domain 1) Rattus norvegicus

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Symbol:

Iqca1

Name:

IQ motif containing with AAA domain 1

RGD ID:

1305311

Description:

Predicted to enable ATP binding activity and ATP hydrolysis activity. Orthologous to human IQCA1 (IQ motif containing with AAA domain 1); INTERACTS WITH bisphenol A; Cuprizon; fenvalerate.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

dynein regulatory complex protein 11; IQ and AAA domain-containing protein 1; IQ motif containing with AAA domain; Iqca; LOC316616; RGD1305311; similar to hypothetical protein FLJ22527

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	98,074,389 - 98,190,233 (-)	NCBI		GRCr8
mRatBN7.2	9	90,626,735 - 90,742,563 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	90,626,744 - 90,742,618 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	9	97,190,240 - 97,298,760 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	97,183,214 - 97,290,639 (-)	NCBI	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	96,873,940 - 96,989,685 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	89,153,670 - 89,273,101 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	89,335,555 - 89,537,162 (-)	NCBI
Celera	9	88,175,143 - 88,290,699 (-)	NCBI		Celera
Cytogenetic Map	9	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Bethlem Myopathy 1A (ISO)

intellectual disability (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3,7,8-tetrachlorodibenzodioxine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

acrolein (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

calcitriol (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

Cuprizon (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

entinostat (ISO)

fenvalerate (EXP)

lithium chloride (ISO)

methapyrilene (ISO)

methylmercury chloride (ISO)

N-methyl-4-phenylpyridinium (ISO)

ozone (ISO)

panobinostat (ISO)

pirinixic acid (ISO)

potassium dichromate (ISO)

rifampicin (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

testosterone (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Molecular Function

ATP binding (IEA)

ATP hydrolysis activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	GOA pipeline	RGD automated data pipeline
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:21873635

Genomics

Comparative Map Data

Iqca1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	98,074,389 - 98,190,233 (-)	NCBI		GRCr8
mRatBN7.2	9	90,626,735 - 90,742,563 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	90,626,744 - 90,742,618 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	9	97,190,240 - 97,298,760 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	97,183,214 - 97,290,639 (-)	NCBI	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	96,873,940 - 96,989,685 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	89,153,670 - 89,273,101 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	89,335,555 - 89,537,162 (-)	NCBI
Celera	9	88,175,143 - 88,290,699 (-)	NCBI		Celera
Cytogenetic Map	9	q36	NCBI

IQCA1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	236,306,685 - 236,507,476 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	236,324,147 - 236,507,535 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	237,232,794 - 237,416,119 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	236,897,533 - 237,080,831 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	237,014,793 - 237,198,092	NCBI
Celera	2	230,945,804 - 231,128,787 (-)	NCBI		Celera
Cytogenetic Map	2	q37.2-q37.3	NCBI
HuRef	2	229,027,057 - 229,210,048 (-)	NCBI		HuRef
CHM1_1	2	237,238,581 - 237,421,557 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	236,813,779 - 236,997,787 (-)	NCBI		T2T-CHM13v2.0

Iqca1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	89,969,854 - 90,081,158 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	89,969,854 - 90,081,123 (-)	Ensembl		GRCm39 Ensembl
GRCm38	1	90,042,132 - 90,153,436 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	90,042,132 - 90,153,401 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	91,938,707 - 92,049,976 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	91,938,707 - 92,049,976 (-)	NCBI		MGSCv36	mm8
Celera	1	92,983,783 - 93,096,895 (-)	NCBI		Celera
Cytogenetic Map	1	D	NCBI
cM Map	1	45.08	NCBI

Iqca1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955453	291,334 - 416,529 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955453	282,601 - 416,715 (+)	NCBI	ChiLan1.0	ChiLan1.0

IQCA1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	138,954,414 - 139,134,752 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	138,969,380 - 139,149,684 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	123,555,491 - 123,735,660 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	242,416,200 - 242,593,852 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	242,416,200 - 242,593,852 (-)	Ensembl	panpan1.1		panPan2

IQCA1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	47,129,449 - 47,276,056 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	47,129,452 - 47,276,074 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	47,625,888 - 47,772,079 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	47,477,271 - 47,623,558 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	47,477,267 - 47,623,606 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	47,385,272 - 47,531,480 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	47,178,551 - 47,324,854 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	47,408,853 - 47,555,398 (-)	NCBI		UU_Cfam_GSD_1.0

Iqca1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	189,198,942 - 189,326,840 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936525	1,621,562 - 1,740,354 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936525	1,613,034 - 1,740,726 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IQCA1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	136,152,982 - 136,321,605 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	136,153,182 - 136,322,725 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	150,587,819 - 150,757,656 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IQCA1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	122,335,436 - 122,500,848 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	122,335,980 - 122,500,711 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	76,900,712 - 77,068,857 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Iqca1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624847	2,008,468 - 2,128,794 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624847	2,008,479 - 2,128,737 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Iqca1
952 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	236
Count of miRNA genes:	96
Interacting mature miRNAs:	104
Transcripts:	ENSRNOT00000026491, ENSRNOT00000056724, ENSRNOT00000068539
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631656	Bp108	Blood pressure QTL 108	5.97	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	48598251	93598251	Rat
724515	Uae16	Urinary albumin excretion QTL 16	8		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	58163035	100929646	Rat
724547	Cm21	Cardiac mass QTL 21	2.7		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	9	79271511	102910209	Rat
731171	Glom6	Glomerulus QTL 6	2.8	0.0003	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	9	64573531	109573531	Rat
8662828	Vetf6	Vascular elastic tissue fragility QTL 6	3.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	9	36962359	92058970	Rat
11353957	Bmd92	Bone mineral density QTL 92		0.01	tibia mineral mass (VT:1000283)	volumetric bone mineral density (CMO:0001553)	9	46114199	91114199	Rat
2303178	Bp334	Blood pressure QTL 334	3.7	0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	79271511	91616855	Rat
61385	Edpm9	Estrogen-dependent pituitary mass QTL 9	3.43	0.05	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	9	63869687	108869687	Rat
724544	Uae9	Urinary albumin excretion QTL 9	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	9	25268044	114175309	Rat
1578760	Cm53	Cardiac mass QTL 53	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	56771635	101771635	Rat
2290450	Scl57	Serum cholesterol level QTL 57	4.15		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	9	36962359	95410867	Rat
1581580	Uae34	Urinary albumin excretion QTL 34			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	62072275	96470995	Rat
1300134	Bp185	Blood pressure QTL 185	3.73		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	61381434	104821652	Rat
1354626	Bvd1	Brain ventricular dilatation QTL 1	3.73	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	9	75712843	111552878	Rat
4889852	Pur26	Proteinuria QTL 26	15	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	77813894	101597663	Rat
7794784	Mcs31	Mammary carcinoma susceptibility QTL 31	2.98		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	9	77813894	111552878	Rat
731164	Uae25	Urinary albumin excretion QTL 25	3.5	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	25661188	100929786	Rat
1578757	Pur6	Proteinuria QTL 6	3.3	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	62072275	96470995	Rat
4889943	Bss90	Bone structure and strength QTL 90	4.1		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	9	86369631	92058970	Rat

Markers in Region

D9Got111

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	90,719,946 - 90,720,113 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	97,276,144 - 97,276,310	NCBI	Rnor6.0
Rnor_5.0	9	96,967,774 - 96,967,940	UniSTS	Rnor5.0
RGSC_v3.4	9	89,249,726 - 89,249,893	RGD	RGSC3.4
RGSC_v3.4	9	89,249,727 - 89,249,893	UniSTS	RGSC3.4
RGSC_v3.1	9	89,454,495 - 89,454,662	RGD
Celera	9	88,267,055 - 88,267,221	UniSTS
RH 2.0 Map	9	927.4	RGD
Cytogenetic Map	9	q35	UniSTS

BE102230

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	90,689,435 - 90,689,651 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	97,245,661 - 97,245,876	NCBI	Rnor6.0
Rnor_5.0	9	96,937,629 - 96,937,844	UniSTS	Rnor5.0
RGSC_v3.4	9	89,218,735 - 89,218,950	UniSTS	RGSC3.4
Celera	9	88,236,574 - 88,236,789	UniSTS
Cytogenetic Map	9	q35	UniSTS

BE110326

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	90,626,787 - 90,626,946 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	97,182,810 - 97,182,968	NCBI	Rnor6.0
Rnor_5.0	9	96,873,536 - 96,873,694	UniSTS	Rnor5.0
RGSC_v3.4	9	89,153,266 - 89,153,424	UniSTS	RGSC3.4
Celera	9	88,175,196 - 88,175,354	UniSTS
RH 3.4 Map	9	784.08	UniSTS
Cytogenetic Map	9	q35	UniSTS

RH140487

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	90,663,687 - 90,663,848 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	97,220,053 - 97,220,213	NCBI	Rnor6.0
Rnor_5.0	9	96,911,877 - 96,912,037	UniSTS	Rnor5.0
RGSC_v3.4	9	89,191,558 - 89,191,718	UniSTS	RGSC3.4
Celera	9	88,211,684 - 88,211,844	UniSTS
Cytogenetic Map	9	q35	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001431271	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_001066515	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017596905	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039084725	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAXUCZ010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000026491 ⟹ ENSRNOP00000026491

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	90,626,744 - 90,742,618 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000056724 ⟹ ENSRNOP00000053565

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	90,626,744 - 90,742,618 (-)	Ensembl

RefSeq Acc Id:

XM_017596905 ⟹ XP_017452394

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	98,074,389 - 98,190,233 (-)	NCBI
mRatBN7.2	9	90,626,735 - 90,742,562 (-)	NCBI
Rnor_6.0	9	97,190,240 - 97,298,760 (-)	NCBI

Sequence:

show sequence

AAACGCATGCAGGAACTGCGCAGAAGTAGAGTCCCCGTTGCTAGGGCCCCCTGGAGCCGCTCTA
GTGGGAGAAGTGGGGTTCCAGAGCCAGAGGCAGCAACCAAAGCGAGGGAACCCCAGTCTGTGCC
TGCGCTCCCGGAGGGTGGTGGCAGGGTGACCCACCCTGTCAAGCCTTACCTACCCCTAAGAGAC
AGGCTGTCCTCCGTCCCTGTCCCTCCCTCCAGAGGAACCCTCAACCTCCGAAAACCTCTGGGGG
TGTTCCCCCAACGTTGGCAGTCAGCCAGCCTTTAGAGGCCAAGGAAAAGCTTTCCTGTGGGTGA
AGGAAAGACGGAAAGAGGCCAGCCATGTCGAACCTAATGTACAATAACATGTGGCACCAGACCC
AAGAAGCCCTCAATTCTCTGCTTGACAAAGAGTCTCAGAAGATGACCGAACCACAAAAAAACAA
GGTCCTAGTCTTTCAGATGTTAGCCACCTTCTACATAAAGTATGTTCAGATCTTCAGGAATATG
GAGAACGTCTATGACCAGATAGTCCATCCACAGAAACGCATGCTAATCCGAAAGATCCTGGATG
GAGTGATGGGTCGCATCCTGGAACTGAAGAACGAGATGGTGGAGCTGGAAATGACAGAGTTCCA
TTATTTTGATGATATCCTACAGGACATGAAGCTGTCTCCTCAACAGTTGGATGTCCCAATACCC
AGGTATTTTCTGAAGGAGAGGCTGGAGGTCATAAAAGGGAGAGAGAAGACCCTCGCTCGGATCT
TGGACGAATGTGGATTGAACCTCCCTGACGTGAAATACGCCGTAAAGAGCATAGCCTTGGAAGA
GGCTGTTAAAATGATCCAGATAGCCGAGCGGGCAAGGCAGGGCCGCCTCAGGGCGATGTTCATG
AAGCAGATCTTCCTCCAGGAGTGCAGAGCCAGGGAGATGAAGCTGCTGGGACACAAACTCTCAG
ACACCACCTTGGCGGCGCTCCAGATTCAGAAAGTTTGGCGAGGTTTCTATCAATGCAAGAAAAC
AGTGAAGGAGCGGGAAGAAGAGATGGTATTCCTGGGTATGAAACCACCCCCTCTCTTCAACGAA
GTCAGTGATGCCATCGTCCAGTCAGAACAAGTGTCAAATCTGCGGGACGAGTTGCAGCTCAAAC
ACGAGCAGAAGTACCAGGAAGCCTTAGTGAGTATCAAGGAGGACCTGCGGCTGTTGGAAGGCGC
AGATATCAAGGAGCACCTGCAGGACCAGATCCGGCAGTGGTTCATAGAATGCAGGAATCTGACG
GGCACATTCCCAGAATACCCTAATGAGGAAGAAGGGGGCTCAGCTGTCATCTTTTCCAACAAGA
CCCCAGAGCAGGTTATCGAGGATATCATAGCCGCCCAAGAGGAGGAAGAAAAATCAAAAAAGAA
AAAGAAGAAAGAAGAAAAGGAGAATAAGGGCAAAAAAGTCAAAAAGGAGAAGGAGAGGAAAACT
GTCACGAAAGAGAAGGCTGCAAAGGAAGAAGATGAGGAATGGAAGATGTCACCAAGTCTTTTCC
TTCAATTGATGGAGGAAGGAAATAGCTTATACAAAGACATGTGGATGAATAAAGATGAATCTTG
GAATTTCCCTCAGGACTATGACCCAGAATTGGTCAAGGAGGAAAAACGGAAGGAATTAGAGATG
GAGATAAGGGTTCAGGTGGACGAGCTGATGAGACAGGAATTGAAAAACCTTAAGCTGGCTGTGA
ACAGAGAGATAGAACCCCAACCCCGGCTAAAGAAAGGGAAAAAGCAAAATAAAGGGAGAAAAGG
CCGGAGAGGGAAACGGGGAAAGAAGGACAAAGACCTGACGGCTGACAGGACCATCGAGTCCCTG
TACCAGGAGCTGGTTGAAGAAGGCCTGCTGATCCAAGCTCTGAAGGTCAAACTCTCCGACTATA
TTGGTGAGTACAGCTACCTGGGGACGACTCTGCGTCAGGTTGCCATAGAGCCCATGCCATCCCT
CCTGGACGTCAGACAGCTCATCACCCTGTATGGAATCTTGCCTCTGGGGTCCGCAGAAGTACAT
GAGAGAGCTCCCTTGGTGAAGTCGCTGCTATTGGCCGGACCCCCAGGGGTAGGGAAGAAAATGC
TGGTCCATGCCATCTGCACAGAAACAGGGGCTAACCTCTTCAACCTGTCTAGCTCAAACATCGC
CGGGAAGTACCCGGGCAAAACCGGCCTGCAGATGATGATACACTTGGTCTTCAAGGTAGCTCGC
CAGCTTCAGCCGTCCGTGGTGTGGATCCAGGACACAGAGAAAACCTTCTACAAGAAAGTCCCGC
AGGCCGAGAAACGGAATGAACCAAAACGCCTAAAAAAATACCTCCCCAAACTCCTGAAGCTCCT
GAGACCAGACGACAGGATCCTGATTGTGGGGACCACACACCGGCCCTTCGATGCCGAGCTTCAG
TCCTTCTGCAGAGTTTACCAAAAGATCATTTTGGTTCCCAGACCCGACTATGCCTCCAGATACG
GCAAGTATCATAGGGCTTTCCACGAGGCACCGAGGCCAAGGACTAGGGCCTGCTTGCAGGCGAG
TAGAGCAGGAGAGCTGTGGGAGGGCTCAGAACAGTGTTTCTCAACCTGTGGTTCACAACCCCTT
TGGGGAATCGAGTATCAGATATCCTACATATCAGATATTTATATCACGATTCATCACAATACAA
AATTGCAGTTATAA

hide sequence

RefSeq Acc Id:

XM_039084725 ⟹ XP_038940653

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	98,095,645 - 98,190,215 (-)	NCBI
mRatBN7.2	9	90,647,765 - 90,742,563 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001418200	(Get FASTA)	NCBI Sequence Viewer
	XP_017452394	(Get FASTA)	NCBI Sequence Viewer
	XP_038940653	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000026491.8
	ENSRNOP00000053565.5

RefSeq Acc Id:

XP_017452394 ⟸ XM_017596905

- Peptide Label:

isoform X1

- Sequence:

show sequence

MSNLMYNNMWHQTQEALNSLLDKESQKMTEPQKNKVLVFQMLATFYIKYVQIFRNMENVYDQIV
HPQKRMLIRKILDGVMGRILELKNEMVELEMTEFHYFDDILQDMKLSPQQLDVPIPRYFLKERL
EVIKGREKTLARILDECGLNLPDVKYAVKSIALEEAVKMIQIAERARQGRLRAMFMKQIFLQEC
RAREMKLLGHKLSDTTLAALQIQKVWRGFYQCKKTVKEREEEMVFLGMKPPPLFNEVSDAIVQS
EQVSNLRDELQLKHEQKYQEALVSIKEDLRLLEGADIKEHLQDQIRQWFIECRNLTGTFPEYPN
EEEGGSAVIFSNKTPEQVIEDIIAAQEEEEKSKKKKKKEEKENKGKKVKKEKERKTVTKEKAAK
EEDEEWKMSPSLFLQLMEEGNSLYKDMWMNKDESWNFPQDYDPELVKEEKRKELEMEIRVQVDE
LMRQELKNLKLAVNREIEPQPRLKKGKKQNKGRKGRRGKRGKKDKDLTADRTIESLYQELVEEG
LLIQALKVKLSDYIGEYSYLGTTLRQVAIEPMPSLLDVRQLITLYGILPLGSAEVHERAPLVKS
LLLAGPPGVGKKMLVHAICTETGANLFNLSSSNIAGKYPGKTGLQMMIHLVFKVARQLQPSVVW
IQDTEKTFYKKVPQAEKRNEPKRLKKYLPKLLKLLRPDDRILIVGTTHRPFDAELQSFCRVYQK
IILVPRPDYASRYGKYHRAFHEAPRPRTRACLQASRAGELWEGSEQCFSTCGSQPLWGIEYQIS
YISDIYITIHHNTKLQL

hide sequence

RefSeq Acc Id:	XP_038940653 ⟸ XM_039084725
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSRNOP00000053565 ⟸ ENSRNOT00000056724

Ensembl Acc Id:

ENSRNOP00000026491 ⟸ ENSRNOT00000026491

Protein Domains

AAA+ ATPase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1M7Z2-F1-model_v2	AlphaFold	F1M7Z2	1-852	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305311	AgrOrtholog
BioCyc Gene	G2FUF-26756	BioCyc
Ensembl Genes	ENSRNOG00000019592	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000026491.9	UniProtKB/TrEMBL
	ENSRNOT00000056724.6	UniProtKB/TrEMBL
Gene3D-CATH	1.10.8.60	UniProtKB/TrEMBL
	3.40.50.300	UniProtKB/TrEMBL
InterPro	AAA+_ATPase	UniProtKB/TrEMBL
	ATPase_AAA_core	UniProtKB/TrEMBL
	N-DRC_Component	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
NCBI Gene	316616	ENTREZGENE
PANTHER	DYNEIN REGULATORY COMPLEX PROTEIN 11	UniProtKB/TrEMBL
	UNCHARACTERIZED	UniProtKB/TrEMBL
Pfam	AAA	UniProtKB/TrEMBL
PhenoGen	Iqca1	PhenoGen
RatGTEx	ENSRNOG00000019592	RatGTEx
SMART	AAA	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	F1LX47	ENTREZGENE, UniProtKB/TrEMBL
	F1M7Z2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-06-02	Iqca1	IQ motif containing with AAA domain 1	Iqca	IQ motif containing with AAA domain	Data merged from RGD:15003483	737654	PROVISIONAL
2021-09-02	Iqca	IQ motif containing with AAA domain	Iqca1	IQ motif containing with AAA domain 1	Symbol and/or name change	19259462	PROVISIONAL
2021-08-09	Iqca1	IQ motif containing with AAA domain 1	Iqca	IQ motif containing with AAA domain	Symbol and/or name change	19259462	PROVISIONAL
2019-11-08	Iqca	IQ motif containing with AAA domain			Symbol and Name status set to provisional	45752	PROVISIONAL
2010-04-23	Iqca1	IQ motif containing with AAA domain 1	RGD1305311	similar to hypothetical protein FLJ22527	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1305311	similar to hypothetical protein FLJ22527	RGD1305311_predicted	similar to hypothetical protein FLJ22527 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-20	RGD1305311_predicted	similar to hypothetical protein FLJ22527 (predicted)	LOC316616_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC316616_predicted	similar to hypothetical protein FLJ22527 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar