IQCA1 (IQ motif containing with AAA domain 1) - Rat Genome Database

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Gene: IQCA1 (IQ motif containing with AAA domain 1) Sus scrofa
Analyze
Symbol: IQCA1
Name: IQ motif containing with AAA domain 1
RGD ID: 14140617
Description: ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ASSOCIATED WITH Bethlem Myopathy 1A (ortholog); genetic disease (ortholog); intellectual disability (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: IQ and AAA domain-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15136,152,982 - 136,321,605 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115136,153,182 - 136,322,725 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215150,587,819 - 150,757,656 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074  


Genomics

Comparative Map Data
IQCA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15136,152,982 - 136,321,605 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115136,153,182 - 136,322,725 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215150,587,819 - 150,757,656 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IQCA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382236,306,685 - 236,507,476 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2236,324,147 - 236,507,535 (-)EnsemblGRCh38hg38GRCh38
GRCh372237,232,794 - 237,416,119 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362236,897,533 - 237,080,831 (-)NCBINCBI36Build 36hg18NCBI36
Build 342237,014,793 - 237,198,092NCBI
Celera2230,945,804 - 231,128,787 (-)NCBICelera
Cytogenetic Map2q37.2-q37.3NCBI
HuRef2229,027,057 - 229,210,048 (-)NCBIHuRef
CHM1_12237,238,581 - 237,421,557 (-)NCBICHM1_1
T2T-CHM13v2.02236,813,779 - 236,997,787 (-)NCBIT2T-CHM13v2.0
Iqca1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39189,969,854 - 90,081,158 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl189,969,854 - 90,081,123 (-)EnsemblGRCm39 Ensembl
GRCm38190,042,132 - 90,153,436 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl190,042,132 - 90,153,401 (-)EnsemblGRCm38mm10GRCm38
MGSCv37191,938,707 - 92,049,976 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36191,938,707 - 92,049,976 (-)NCBIMGSCv36mm8
Celera192,983,783 - 93,096,895 (-)NCBICelera
Cytogenetic Map1DNCBI
cM Map145.08NCBI
Iqca1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8998,074,389 - 98,190,233 (-)NCBIGRCr8
mRatBN7.2990,626,735 - 90,742,563 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl990,626,744 - 90,742,618 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0997,190,240 - 97,298,760 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl997,183,214 - 97,290,639 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0996,873,940 - 96,989,685 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4989,153,670 - 89,273,101 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1989,335,555 - 89,537,162 (-)NCBI
Celera988,175,143 - 88,290,699 (-)NCBICelera
Cytogenetic Map9q36NCBI
Iqca1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955453291,334 - 416,529 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955453282,601 - 416,715 (+)NCBIChiLan1.0ChiLan1.0
IQCA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213138,954,414 - 139,134,752 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B138,969,380 - 139,149,684 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B123,555,491 - 123,735,660 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B242,416,200 - 242,593,852 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B242,416,200 - 242,593,852 (-)Ensemblpanpan1.1panPan2
IQCA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12547,129,449 - 47,276,056 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2547,129,452 - 47,276,074 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2547,625,888 - 47,772,079 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02547,477,271 - 47,623,558 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2547,477,267 - 47,623,606 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12547,385,272 - 47,531,480 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02547,178,551 - 47,324,854 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02547,408,853 - 47,555,398 (-)NCBIUU_Cfam_GSD_1.0
Iqca1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303189,198,942 - 189,326,840 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365251,621,562 - 1,740,354 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365251,613,034 - 1,740,726 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IQCA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110122,335,436 - 122,500,848 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10122,335,980 - 122,500,711 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604076,900,712 - 77,068,857 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Iqca1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248472,008,468 - 2,128,794 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248472,008,479 - 2,128,737 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in IQCA1
8962 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system nervous system reproductive system
High
Medium
Low 6 2
Below cutoff 1 12

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000017774   ⟹   ENSSSCP00000017293
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl15136,152,982 - 136,321,605 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000051935   ⟹   ENSSSCP00000035427
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl15136,152,982 - 136,321,605 (-)Ensembl
RefSeq Acc Id: XM_013984621   ⟹   XP_013840075
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115136,153,182 - 136,322,725 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013840075 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000017293
  ENSSSCP00000017293.5
  ENSSSCP00000035427.3
  ENSSSCP00005008884.1
  ENSSSCP00050008691.1
  ENSSSCP00055013622.1
Reference Protein Sequences
RefSeq Acc Id: XP_013840075   ⟸   XM_013984621
- UniProtKB: A0A8D1Q785 (UniProtKB/TrEMBL),   A0A8D0IAS3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000035427   ⟸   ENSSSCT00000051935
RefSeq Acc Id: ENSSSCP00000017293   ⟸   ENSSSCT00000017774
Protein Domains
AAA+ ATPase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000016321 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005009376 UniProtKB/TrEMBL
  ENSSSCG00050015342 UniProtKB/TrEMBL
  ENSSSCG00055008817 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000017774 ENTREZGENE
  ENSSSCT00000017774.5 UniProtKB/TrEMBL
  ENSSSCT00000051935.3 UniProtKB/TrEMBL
  ENSSSCT00005014885.1 UniProtKB/TrEMBL
  ENSSSCT00050020803.1 UniProtKB/TrEMBL
  ENSSSCT00055017240.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.8.60 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  ATPase_AAA_core UniProtKB/TrEMBL
  IQ_motif_EF-hand-BS UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene IQCA1 ENTREZGENE
PANTHER DYNEIN REGULATORY COMPLEX PROTEIN 11 UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/TrEMBL
Pfam AAA UniProtKB/TrEMBL
PROSITE PS50096 UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A286ZVD9_PIG UniProtKB/TrEMBL
  A0A8D0IAS3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1Q785 ENTREZGENE, UniProtKB/TrEMBL
  F1SM09_PIG UniProtKB/TrEMBL
VGNC ID VGNC:96117 ENTREZGENE