Hsd17b11 (hydroxysteroid (17-beta) dehydrogenase 11) - Rat Genome Database

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Gene: Hsd17b11 (hydroxysteroid (17-beta) dehydrogenase 11) Rattus norvegicus
Analyze
Symbol: Hsd17b11
Name: hydroxysteroid (17-beta) dehydrogenase 11
RGD ID: 1303235
Description: Predicted to enable estradiol 17-beta-dehydrogenase [NAD(P)] activity. Predicted to be involved in androgen catabolic process. Predicted to be located in cytoplasm. Predicted to be active in lipid droplet. Orthologous to human HSD17B11 (hydroxysteroid 17-beta dehydrogenase 11); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 17-beta-HSD 11; 17-beta-HSD XI; 17-beta-hydroxysteroid dehydrogenase 11; 17-beta-hydroxysteroid dehydrogenase XI; 17betaHSD11; 17betaHSDXI; 17bHSD11; dehydrogenase/reductase (SDR family) member 8; dehydrogenase/reductase SDR family member 8; Dhrs8; estradiol 17-beta-dehydrogenase 11; MGC93725
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8145,997,893 - 6,047,816 (+)NCBIGRCr8
mRatBN7.2145,693,304 - 5,743,157 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl145,711,964 - 5,743,161 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx145,680,838 - 5,711,943 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0146,981,070 - 7,012,171 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0145,679,602 - 5,710,704 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0147,054,724 - 7,104,567 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl147,073,445 - 7,104,566 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0147,045,735 - 7,095,462 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4146,859,573 - 6,891,511 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1146,859,572 - 6,891,510 (+)NCBI
Celera145,850,785 - 5,881,812 (+)NCBICelera
Cytogenetic Map14p22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methylcholine  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
aconitine  (EXP)
acrylamide  (EXP)
afimoxifene  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
amphetamine  (EXP)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
Butylbenzyl phthalate  (EXP)
cadmium dichloride  (EXP)
calcitriol  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
ciprofibrate  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
clofibric acid  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
deguelin  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dichloroacetic acid  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
dipentyl phthalate  (EXP)
diuron  (EXP)
doxorubicin  (ISO)
elemental selenium  (ISO)
fenthion  (ISO)
fipronil  (ISO)
flutamide  (EXP)
folpet  (ISO)
FR900359  (ISO)
genistein  (ISO)
glafenine  (EXP)
heptanal  (ISO)
hexanal  (ISO)
hydrogen peroxide  (ISO)
inulin  (ISO)
ivermectin  (ISO)
menadione  (ISO)
methidathion  (ISO)
N,N-diethyl-m-toluamide  (ISO)
N-nitrosodiethylamine  (ISO)
NAD zwitterion  (ISO)
NAD(+)  (ISO)
nonanal  (ISO)
octanal  (ISO)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
propanal  (ISO)
raloxifene  (ISO)
rotenone  (ISO)
selenium atom  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
tolcapone  (EXP)
trichloroethene  (EXP,ISO)
triphenyl phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:12697717   PMID:14741744   PMID:15489334   PMID:18775470   PMID:36849008  


Genomics

Comparative Map Data
Hsd17b11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8145,997,893 - 6,047,816 (+)NCBIGRCr8
mRatBN7.2145,693,304 - 5,743,157 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl145,711,964 - 5,743,161 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx145,680,838 - 5,711,943 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0146,981,070 - 7,012,171 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0145,679,602 - 5,710,704 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0147,054,724 - 7,104,567 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl147,073,445 - 7,104,566 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0147,045,735 - 7,095,462 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4146,859,573 - 6,891,511 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1146,859,572 - 6,891,510 (+)NCBI
Celera145,850,785 - 5,881,812 (+)NCBICelera
Cytogenetic Map14p22NCBI
HSD17B11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38487,336,515 - 87,391,188 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl487,336,515 - 87,391,188 (-)EnsemblGRCh38hg38GRCh38
GRCh37488,257,667 - 88,312,340 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36488,476,715 - 88,531,479 (-)NCBINCBI36Build 36hg18NCBI36
Build 34488,614,943 - 88,669,507NCBI
Celera485,546,623 - 85,601,607 (-)NCBICelera
Cytogenetic Map4q22.1NCBI
HuRef484,003,415 - 84,058,302 (-)NCBIHuRef
CHM1_1488,234,791 - 88,289,311 (-)NCBICHM1_1
T2T-CHM13v2.0490,665,555 - 90,720,229 (-)NCBIT2T-CHM13v2.0
Hsd17b11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395104,137,631 - 104,169,662 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5104,137,628 - 104,169,785 (-)EnsemblGRCm39 Ensembl
GRCm385103,989,765 - 104,021,796 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5103,989,762 - 104,021,919 (-)EnsemblGRCm38mm10GRCm38
MGSCv375104,418,784 - 104,450,815 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365104,230,067 - 104,262,098 (-)NCBIMGSCv36mm8
Celera5101,296,457 - 101,328,096 (-)NCBICelera
Cytogenetic Map5E5NCBI
cM Map550.52NCBI
Hsd17b11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554742,472,876 - 2,512,651 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554742,477,670 - 2,510,424 (+)NCBIChiLan1.0ChiLan1.0
HSD17B11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2385,352,606 - 85,401,481 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1485,613,872 - 85,663,847 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0479,638,500 - 79,687,204 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1490,364,769 - 90,413,522 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl490,364,769 - 90,413,522 (-)Ensemblpanpan1.1panPan2
HSD17B11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13210,821,332 - 10,854,541 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3210,794,617 - 10,854,193 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3231,099,926 - 31,132,979 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03210,873,296 - 10,906,759 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3210,845,726 - 10,906,673 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13210,954,508 - 10,987,556 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03210,782,541 - 10,815,990 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03229,139,474 - 29,172,518 (+)NCBIUU_Cfam_GSD_1.0
HSD17B13
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8131,555,594 - 131,569,990 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18131,555,517 - 131,570,067 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28140,763,903 - 140,778,297 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HSD17B11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1735,715,493 - 35,777,245 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl735,714,925 - 35,777,229 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603714,412,769 - 14,476,882 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hsd17b11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248723,880,517 - 3,904,561 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248723,881,066 - 3,904,560 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hsd17b11
320 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:67
Count of miRNA genes:55
Interacting mature miRNAs:62
Transcripts:ENSRNOT00000003004
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300159Bmd61Bone mineral density QTL 615.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat
2300183Bmd60Bone mineral density QTL 605.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat
619619Rf4Renal disease susceptibility QTL 44.10.002urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)14132754612Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141131407Rat
71115Niddm15Non-insulin dependent diabetes mellitus QTL 154.8blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14121760611030812Rat
70204Niddm20Non-insulin dependent diabetes mellitus QTL 205.10.000008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)14121760616960180Rat
724541Niddm53Non-insulin dependent diabetes mellitus QTL 530.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1438130749088978Rat
2293089Iddm31Insulin dependent diabetes mellitus QTL 314.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)14381307418274691Rat
2293089Iddm31Insulin dependent diabetes mellitus QTL 314.7blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)14381307418274691Rat
1300114Srn2Serum renin concentration QTL 23.27blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)14381307421217635Rat
70195Mcs8Mammary carcinoma susceptibility QTL 84.28mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)14381307424531477Rat
1331740Bw26Body weight QTL 263.028body mass (VT:0001259)body weight (CMO:0000012)14381307430767156Rat

Markers in Region
RH128489  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2145,742,773 - 5,742,965 (+)MAPPERmRatBN7.2
Rnor_6.0147,104,184 - 7,104,375NCBIRnor6.0
Rnor_5.0147,095,079 - 7,095,270UniSTSRnor5.0
RGSC_v3.4146,891,128 - 6,891,319UniSTSRGSC3.4
Celera145,881,429 - 5,881,620UniSTS
RH 3.4 Map14114.1UniSTS
Cytogenetic Map14p22UniSTS
RH131195  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2145,742,943 - 5,743,130 (+)MAPPERmRatBN7.2
Rnor_6.0147,104,354 - 7,104,540NCBIRnor6.0
Rnor_5.0147,095,249 - 7,095,435UniSTSRnor5.0
RGSC_v3.4146,891,298 - 6,891,484UniSTSRGSC3.4
Celera145,881,599 - 5,881,785UniSTS
RH 3.4 Map14114.3UniSTS
Cytogenetic Map14p22UniSTS
RH143502  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2145,736,206 - 5,736,367 (+)MAPPERmRatBN7.2
Rnor_6.0147,097,621 - 7,097,781NCBIRnor6.0
Rnor_5.0147,088,516 - 7,088,676UniSTSRnor5.0
RGSC_v3.4146,884,565 - 6,884,725UniSTSRGSC3.4
Celera145,874,880 - 5,875,040UniSTS
RH 3.4 Map14114.6UniSTS
Cytogenetic Map14p22UniSTS
BE096901  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2145,732,528 - 5,732,727 (+)MAPPERmRatBN7.2
Rnor_6.0147,093,943 - 7,094,141NCBIRnor6.0
Rnor_5.0147,084,838 - 7,085,036UniSTSRnor5.0
RGSC_v3.4146,880,887 - 6,881,085UniSTSRGSC3.4
Celera145,871,202 - 5,871,400UniSTS
RH 3.4 Map14114.9UniSTS
Cytogenetic Map14p22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 24 57 41 19 41 2 2 46 35 38 11 2
Low 19 6 9 28 3 6
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000003004   ⟹   ENSRNOP00000003004
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl145,711,964 - 5,743,161 (+)Ensembl
Rnor_6.0 Ensembl147,073,445 - 7,104,566 (+)Ensembl
RefSeq Acc Id: NM_001004209   ⟹   NP_001004209
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8146,016,690 - 6,047,812 (+)NCBI
mRatBN7.2145,712,031 - 5,743,157 (+)NCBI
Rnor_6.0147,073,445 - 7,104,567 (+)NCBI
Rnor_5.0147,045,735 - 7,095,462 (+)NCBI
RGSC_v3.4146,859,573 - 6,891,511 (+)RGD
Celera145,850,785 - 5,881,812 (+)RGD
Sequence:
RefSeq Acc Id: XM_006250627   ⟹   XP_006250689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8146,001,718 - 6,047,816 (+)NCBI
mRatBN7.2145,697,053 - 5,743,157 (+)NCBI
Rnor_6.0147,058,508 - 7,104,567 (+)NCBI
Rnor_5.0147,045,735 - 7,095,462 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006250629   ⟹   XP_006250691
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8145,997,893 - 6,047,816 (+)NCBI
mRatBN7.2145,693,304 - 5,743,157 (+)NCBI
Rnor_6.0147,054,795 - 7,104,567 (+)NCBI
Rnor_5.0147,045,735 - 7,095,462 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063272893   ⟹   XP_063128963
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8145,997,905 - 6,047,816 (+)NCBI
RefSeq Acc Id: XM_063272894   ⟹   XP_063128964
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8145,997,915 - 6,047,816 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001004209   ⟸   NM_001004209
- Peptide Label: precursor
- UniProtKB: Q6AYS8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006250691   ⟸   XM_006250629
- Peptide Label: isoform X1
- UniProtKB: Q6AYS8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006250689   ⟸   XM_006250627
- Peptide Label: isoform X1
- UniProtKB: Q6AYS8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000003004   ⟸   ENSRNOT00000003004
RefSeq Acc Id: XP_063128963   ⟸   XM_063272893
- Peptide Label: isoform X1
- UniProtKB: Q6AYS8 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063128964   ⟸   XM_063272894
- Peptide Label: isoform X1
- UniProtKB: Q6AYS8 (UniProtKB/Swiss-Prot)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AYS8-F1-model_v2 AlphaFold Q6AYS8 1-298 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699178
Promoter ID:EPDNEW_R9702
Type:initiation region
Name:Hsd17b11_1
Description:hydroxysteroid (17-beta) dehydrogenase 11
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0147,073,426 - 7,073,486EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303235 AgrOrtholog
BioCyc Gene G2FUF-16496 BioCyc
Ensembl Genes ENSRNOG00000002210 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055026190 UniProtKB/Swiss-Prot
  ENSRNOG00060010768 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000003004 ENTREZGENE
  ENSRNOT00000003004.7 UniProtKB/Swiss-Prot
  ENSRNOT00055045193 UniProtKB/Swiss-Prot
  ENSRNOT00060018228 UniProtKB/Swiss-Prot
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7107084 IMAGE-MGC_LOAD
InterPro NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot
  SDR_fam UniProtKB/Swiss-Prot
KEGG Report rno:289456 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93725 IMAGE-MGC_LOAD
NCBI Gene 289456 ENTREZGENE
PANTHER ESTRADIOL 17-BETA-DEHYDROGENASE 11 UniProtKB/Swiss-Prot
  PKSB UniProtKB/Swiss-Prot
Pfam adh_short UniProtKB/Swiss-Prot
PhenoGen Hsd17b11 PhenoGen
PRINTS GDHRDH UniProtKB/Swiss-Prot
  SDRFAMILY UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000002210 RatGTEx
  ENSRNOG00055026190 RatGTEx
  ENSRNOG00060010768 RatGTEx
Superfamily-SCOP SSF51735 UniProtKB/Swiss-Prot
UniProt DHB11_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-03 Hsd17b11  hydroxysteroid (17-beta) dehydrogenase 11  Dhrs8  dehydrogenase/reductase (SDR family) member 8  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Dhrs8  dehydrogenase/reductase (SDR family) member 8      Symbol and Name status set to approved 1299863 APPROVED
2005-09-30 Dhrs8        Symbol and Name status set to provisional 70820 PROVISIONAL