Fscn1 (fascin actin-bundling protein 1) - Rat Genome Database

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Pathways
Gene: Fscn1 (fascin actin-bundling protein 1) Ictidomys tridecemlineatus
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Symbol: Fscn1
Name: fascin actin-bundling protein 1
RGD ID: 12502567
Description: ENCODES a protein that exhibits actin binding (ortholog); INVOLVED IN actin filament bundle assembly (ortholog); cellular response to cell-matrix adhesion (ortholog); liver development (ortholog); PARTICIPATES IN protein kinase C (PKC) signaling pathway; ASSOCIATED WITH basal cell carcinoma (ortholog); Bile Duct Neoplasms (ortholog); cholangiocarcinoma (ortholog); FOUND IN dendrite (ortholog); filopodium (ortholog); growth cone (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: fascin; fascin homolog 1, actin-bundling protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344140,618,834 - 140,628,367 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936765609,861 - 619,456 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936765609,894 - 619,417 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Fscn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344140,618,834 - 140,628,367 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936765609,861 - 619,456 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936765609,894 - 619,417 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FSCN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3875,592,816 - 5,606,655 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl75,592,809 - 5,606,655 (+)Ensemblhg38GRCh38
GRCh3775,632,447 - 5,646,286 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3675,598,980 - 5,612,812 (+)NCBIBuild 36Build 36hg18NCBI36
Build 3475,405,694 - 5,419,526NCBI
Celera75,592,071 - 5,605,904 (+)NCBICelera
Cytogenetic Map7p22.1NCBI
HuRef75,544,716 - 5,558,303 (+)NCBIHuRef
CHM1_175,632,035 - 5,645,887 (+)NCBICHM1_1
T2T-CHM13v2.075,710,346 - 5,724,185 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v275,678,781 - 5,692,632 (+)NCBI
Fscn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395142,946,110 - 142,958,944 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5142,946,098 - 142,958,940 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm385142,960,355 - 142,973,189 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5142,960,343 - 142,973,185 (+)Ensemblmm10GRCm38
MGSCv375143,722,034 - 143,734,868 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365143,225,511 - 143,238,323 (+)NCBIMGSCv36mm8
Celera5140,008,743 - 140,021,597 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map581.84NCBI
Fscn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81216,710,601 - 16,723,734 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1216,710,601 - 16,723,734 (-)EnsemblGRCr8
mRatBN7.21211,597,042 - 11,610,183 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1211,597,048 - 11,610,211 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1212,407,106 - 12,420,219 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01213,030,380 - 13,043,493 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01212,056,462 - 12,069,553 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1218,194,591 - 18,207,296 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive1218,120,735 - 18,133,440 (-)NCBILyon_Normotensive
Lyon_Hypertensive1216,979,437 - 16,992,192 (-)NCBILyon_Hypertensive
F344_StmMcwi1227,557,895 - 27,570,600 (-)NCBIF344_StmMcwi
Rnor_6.01213,655,459 - 13,668,595 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1213,656,554 - 13,668,515 (-)Ensemblrn6Rnor6.0
Rnor_5.01215,688,989 - 15,702,125 (-)NCBIRnor_5.0Rnor_5.0rn5
Celera1213,390,657 - 13,403,285 (-)NCBICelera
Cytogenetic Map12p11NCBI
Fscn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546010,402,855 - 10,412,710 (+)Ensembl
ChiLan1.0NW_00495546010,402,855 - 10,412,459 (+)NCBIChiLan1.0ChiLan1.0
FSCN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2610,558,399 - 10,572,274 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1758,883,132 - 58,896,979 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v075,848,902 - 5,862,756 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.175,865,307 - 5,877,366 (+)NCBIPanPan1.1PanPan1.1panPan2
FSCN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1612,360,849 - 12,370,906 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl612,354,599 - 12,370,808 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha613,832,769 - 13,842,836 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0612,496,810 - 12,506,878 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl612,434,187 - 12,506,926 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1612,307,279 - 12,317,591 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0612,241,487 - 12,251,542 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0612,518,817 - 12,528,874 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
FSCN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl34,134,177 - 4,143,286 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.134,134,173 - 4,143,275 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.234,776,501 - 4,785,603 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FSCN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12816,127,033 - 16,142,285 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2816,127,015 - 16,142,337 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660905,849,807 - 5,864,040 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fscn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474028,036,731 - 28,047,364 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474028,038,216 - 28,047,252 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Fscn1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11610,172,024 - 10,184,796 (-)NCBIRrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000029770   ⟹   ENSSTOP00000021848
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936765609,861 - 619,456 (-)Ensembl
Ensembl Acc Id: ENSSTOT00000030193   ⟹   ENSSTOP00000029421
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936765611,015 - 619,299 (-)Ensembl
RefSeq Acc Id: XM_005340037   ⟹   XP_005340094
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344140,618,834 - 140,628,367 (-)NCBI
SpeTri2.0NW_004936765609,894 - 619,417 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005340094 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000021848.2
  ENSSTOP00000029421.1
  ENSSTOP00015024798
GenBank Protein KAG3260090 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005340094   ⟸   XM_005340037
- UniProtKB: I3NBV1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSTOP00000021848   ⟸   ENSSTOT00000029770
Ensembl Acc Id: ENSSTOP00000029421   ⟸   ENSSTOT00000030193
Protein Domains
Fascin-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000020923 Ensembl, UniProtKB/TrEMBL
  ENSSTOG00015020155 ENTREZGENE
Ensembl Transcript ENSSTOT00000029770.2 UniProtKB/TrEMBL
  ENSSTOT00000030193.1 UniProtKB/TrEMBL
Gene3D-CATH 2.80.10.50 UniProtKB/TrEMBL
InterPro Actin-crosslinking UniProtKB/TrEMBL
  Fascin UniProtKB/TrEMBL
  Fascin-domain UniProtKB/TrEMBL
  Fascin_metazoans UniProtKB/TrEMBL
KEGG Report iti:101958362 UniProtKB/TrEMBL
NCBI Gene Fscn1 ENTREZGENE
PANTHER PTHR10551 UniProtKB/TrEMBL
  PTHR10551:SF23 UniProtKB/TrEMBL
Pfam Fascin UniProtKB/TrEMBL
PIRSF Fascin UniProtKB/TrEMBL
Superfamily-SCOP SSF50405 UniProtKB/TrEMBL
UniProt A0A287D7D2_ICTTR UniProtKB/TrEMBL
  I3NBV1 ENTREZGENE, UniProtKB/TrEMBL