FSCN1 (fascin actin-bundling protein 1) - Rat Genome Database
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Gene: FSCN1 (fascin actin-bundling protein 1) Sus scrofa
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Symbol: FSCN1
Name: fascin actin-bundling protein 1
RGD ID: 14138399
Description: ENCODES a protein that exhibits actin binding (ortholog); actin filament binding (ortholog); drug binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); actin filament bundle assembly (ortholog); cell migration (ortholog); PARTICIPATES IN protein kinase C (PKC) signaling pathway; ASSOCIATED WITH Bile Duct Neoplasms (ortholog); cholangiocarcinoma (ortholog); common bile duct neoplasm (ortholog); FOUND IN actin cytoskeleton (ortholog); cytoplasm (ortholog); cytoskeleton (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: fascin; fascin homolog 1, actin-bundling protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl34,134,170 - 4,145,394 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.134,134,173 - 4,143,275 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.234,776,501 - 4,785,603 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:19688270  


Genomics

Comparative Map Data
FSCN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl34,134,170 - 4,145,394 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.134,134,173 - 4,143,275 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.234,776,501 - 4,785,603 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FSCN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl75,592,816 - 5,606,655 (+)EnsemblGRCh38hg38GRCh38
GRCh3875,592,816 - 5,606,655 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3775,632,436 - 5,646,287 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh3775,632,447 - 5,646,286 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3675,598,980 - 5,612,812 (+)NCBINCBI36hg18NCBI36
Build 3475,405,694 - 5,419,526NCBI
Celera75,592,071 - 5,605,904 (+)NCBI
Cytogenetic Map7p22.1NCBI
HuRef75,544,716 - 5,558,303 (+)NCBIHuRef
CHM1_175,632,035 - 5,645,887 (+)NCBICHM1_1
CRA_TCAGchr7v275,678,781 - 5,692,632 (+)NCBI
Fscn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395142,946,110 - 142,958,944 (+)NCBIGRCm39mm39
GRCm385142,960,355 - 142,973,189 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5142,960,343 - 142,973,185 (+)EnsemblGRCm38mm10GRCm38
MGSCv375143,722,034 - 143,734,868 (+)NCBIGRCm37mm9NCBIm37
MGSCv365143,225,511 - 143,238,323 (+)NCBImm8
Celera5140,008,743 - 140,021,597 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map581.84NCBI
Fscn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21211,597,042 - 11,610,183 (-)NCBI
Rnor_6.0 Ensembl1213,656,554 - 13,668,515 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01213,655,459 - 13,668,595 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01215,688,989 - 15,702,125 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1213,390,657 - 13,403,285 (-)NCBICelera
Cytogenetic Map12p11NCBI
Fscn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546010,402,855 - 10,412,710 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546010,402,855 - 10,412,459 (+)NCBIChiLan1.0ChiLan1.0
FSCN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.175,865,307 - 5,877,366 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v075,848,902 - 5,862,756 (+)NCBIMhudiblu_PPA_v0panPan3
FSCN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl612,354,599 - 12,370,808 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1612,360,849 - 12,370,906 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Fscn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936765609,894 - 619,417 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FSCN1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12816,127,033 - 16,142,285 (-)NCBI
ChlSab1.1 Ensembl2816,127,015 - 16,142,337 (-)Ensembl
Fscn1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474028,038,216 - 28,047,252 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 15 1
Low 10 4 3 4 2 8 2 2 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000026008   ⟹   ENSSSCP00000024567
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl34,134,170 - 4,145,394 (+)Ensembl
RefSeq Acc Id: NM_001146300   ⟹   NP_001139772
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.134,134,173 - 4,143,275 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001139772 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ACN89281 (Get FASTA)   NCBI Sequence Viewer  
  ACN89282 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001139772   ⟸   NM_001146300
- UniProtKB: C0LZL0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000024567   ⟸   ENSSSCT00000026008
Protein Domains
Fascin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000007586 Ensembl, UniProtKB/TrEMBL
  ENSSSCG00070011455 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000024567 UniProtKB/TrEMBL
  ENSSSCP00070018461 UniProtKB/TrEMBL
  ENSSSCP00070018470 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000026008 UniProtKB/TrEMBL
  ENSSSCT00070022300 UniProtKB/TrEMBL
  ENSSSCT00070022311 UniProtKB/TrEMBL
InterPro Actin-crosslinking UniProtKB/TrEMBL
  Fascin UniProtKB/TrEMBL
  Fascin-domain UniProtKB/TrEMBL
  Fascin_metazoans UniProtKB/TrEMBL
  FSCN1 UniProtKB/TrEMBL
KEGG Report ssc:100286741 UniProtKB/TrEMBL
NCBI Gene FSCN1 ENTREZGENE
PANTHER PTHR10551 UniProtKB/TrEMBL
  PTHR10551:SF23 UniProtKB/TrEMBL
Pfam Fascin UniProtKB/TrEMBL
PIRSF Fascin UniProtKB/TrEMBL
Superfamily-SCOP SSF50405 UniProtKB/TrEMBL
UniProt A0A4X1TNB7_PIG UniProtKB/TrEMBL
  A0A4X1TSZ4_PIG UniProtKB/TrEMBL
  C0LZL0 ENTREZGENE, UniProtKB/TrEMBL
  C0LZL1_PIG UniProtKB/TrEMBL
  I3LKF3_PIG UniProtKB/TrEMBL
UniProt Secondary F1RFN9 UniProtKB/TrEMBL
VGNC ID VGNC:88248 ENTREZGENE