| 9000006 | Caly | calcyon neuron specific vesicular protein | ENCODES a protein that exhibits clathrin light chain binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN anterograde axonal transport (ortholog); clathrin coat assembly (ortholog); positive regulation of clathrin coat assembly (ortholog); ASSOCIATED WITH Animal Disease Mod els (ortholog); attention deficit hyperactivity disorder (ortholog); essential hypertension (ortholog); FOUND IN axon (ortholog); cytoplasmic vesicle (ortholog); glutamatergic synapse (ortholog) | NW_004955477 | 10983602 | 10993371 | Chinchilla | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 8853612 | Aak1 | AP2 associated kinase 1 | ENCODES a protein that exhibits AP-2 adaptor complex binding (ortholog); Notch binding (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN positive regulation of Notch signaling pathway (ortholog); presynaptic endocytosis (ortholog); protein phosphorylation (ortholog); ASSOC IATED WITH tooth agenesis (ortholog); FOUND IN calyx of Held (ortholog); cell leading edge (ortholog); clathrin complex (ortholog) | NW_004955424 | 15480783 | 15640471 | Chinchilla | 24 | description | gene, protein-coding, MODEL [RefSeq] |
| 8901313 | Atp1a3 | ATPase Na+/K+ transporting subunit alpha 3 | ENCODES a protein that exhibits amyloid-beta binding (ortholog); D1 dopamine receptor binding (ortholog); heparan sulfate proteoglycan binding (ortholog); INVOLVED IN adult locomotory behavior (ortholog); blood circulation (ortholog); brain-derived neurotrophic factor receptor signaling pathway (ort holog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; ASSOCIATED WITH alternating hemiplegia of childhood (ortholog); Alternating Hemiplegia of Childhood 2 (ortholog); autism spectrum disorder (ortholog); FOUND IN axon (ortholog); calyx of Held (ortholog); cell surface (ortholog) | NW_004955555 | 869508 | 892510 | Chinchilla | 253 | description | gene, protein-coding, MODEL [RefSeq] |
| 8866424 | Cacna1a | calcium voltage-gated channel subunit alpha1 A | ENCODES a protein that exhibits calmodulin binding (ortholog); high voltage-gated calcium channel activity (ortholog); syntaxin binding (ortholog); INVOLVED IN adult walking behavior (ortholog); behavioral response to pain (ortholog); calcium ion import (ortholog); PARTICIPATES IN alfentanil pharmac odynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; ASSOCIATED WITH Alternating Hemiplegia of Childhood 1 (ortholog); amyotrophic lateral sclerosis (ortholog); Ataxia (ortholog); FOUND IN dendrite; neuronal cell body; calyx of Held (ortholog) | NW_004955415 | 32182536 | 32457511 | Chinchilla | 239 | description | gene, protein-coding, MODEL [RefSeq] |
| 8775056 | Calb2 | calbindin 2 | ENCODES a protein that exhibits calcium ion binding (ortholog); calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration (ortholog); INVOLVED IN intracellular calcium ion homeostasis (ortholog); regulation of synaptic plasticity (ortholog); synaptic signaling (or tholog); PARTICIPATES IN calcium/calcium-mediated signaling pathway; ASSOCIATED WITH amyotrophic lateral sclerosis type 1 (ortholog); Endometrial Neoplasms (ortholog); malignant mesothelioma (ortholog); FOUND IN neuronal cell body; vestibular calyx terminal; cuticular plate (ortholog) | NW_004955484 | 4075103 | 4103509 | Chinchilla | 24 | description | gene, protein-coding, MODEL [RefSeq] |
| 8824130 | Calm1 | calmodulin 1 | ENCODES a protein that exhibits adenylate cyclase activator activity (ortholog); adenylate cyclase binding (ortholog); calcium channel inhibitor activity (ortholog); INVOLVED IN autophagosome membrane docking (ortholog); calcineurin-mediated signaling (ortholog); cellular response to interferon-beta (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adenosine monophosphate-activated protein kinase (AMPK) signaling pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; ASSOCIATED WITH alcohol dependence (ortholog); alcohol withdrawal syndrome (ortholog); Alzheimer's disease (ortholog); FOUND IN calcium channel complex (ortholog); calyx of Held (ortholog); catalytic complex (ortholog) | NW_004955438 | 12842437 | 12854028 | Chinchilla | 163 | description | gene, protein-coding, MODEL [RefSeq] |
| 8966209 | Calm2 | calmodulin 2 | ENCODES a protein that exhibits adenylate cyclase activator activity (ortholog); adenylate cyclase binding (ortholog); calcium channel inhibitor activity (ortholog); INVOLVED IN autophagosome membrane docking (ortholog); calcineurin-mediated signaling (ortholog); cellular response to interferon-beta (ortholog); PARTICIPATES IN adenosine monophosphate-activated protein kinase (AMPK) signaling pathway; calcium/calcium-mediated signaling pathway; calcium/calmodulin dependent kinase 2 signaling pathway; ASSOCIATED WITH alcohol dependence (ortholog); alcohol withdrawal syndrome (ortholog); cannabis abuse (ortholog); FOUND IN calcium channel complex (ortholog); calyx of Held (ortholog); catalytic complex (ortholog) | NW_004955441 | 13973147 | 13988665 | Chinchilla | 122 | description | gene, protein-coding, MODEL [RefSeq] |
| 9050103 | Calm3 | calmodulin 3 | ENCODES a protein that exhibits adenylate cyclase activator activity (ortholog); adenylate cyclase binding (ortholog); calcium channel inhibitor activity (ortholog); INVOLVED IN autophagosome membrane docking (ortholog); calcineurin-mediated signaling (ortholog); cellular response to interferon-beta (ortholog); PARTICIPATES IN adenosine monophosphate-activated protein kinase (AMPK) signaling pathway; calcium/calcium-mediated signaling pathway; calcium/calmodulin dependent kinase 2 signaling pathway; ASSOCIATED WITH alcohol dependence (ortholog); alcohol withdrawal syndrome (ortholog); Cardiac Arrhythmias (ortholog); FOUND IN calcium channel complex (ortholog); calyx of Held (ortholog); catalytic complex (ortholog) | NW_004955574 | 672441 | 680924 | Chinchilla | 106 | description | gene, protein-coding, MODEL [RefSeq] |
| 8990865 | Ccin | calicin | INVOLVED IN spermatogenesis (ortholog); ASSOCIATED WITH spermatogenic failure 91 (ortholog); FOUND IN cytoskeletal calyx (ortholog); perinuclear theca (ortholog); sperm glycocalyx (ortholog) | NW_004958151 | 6 | 1111 | Chinchilla | 10 | description | gene, protein-coding, MODEL [RefSeq] |
| 8743540 | Cplx1 | complexin 1 | ENCODES a protein that exhibits lipid binding (ortholog); SNARE binding (ortholog); syntaxin-1 binding (ortholog); INVOLVED IN insulin secretion (ortholog); regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane (ortholog); regulation of synaptic vesicle fusion to pre synaptic active zone membrane (ortholog); ASSOCIATED WITH Ataxia (ortholog); bipolar disorder (ortholog); developmental and epileptic encephalopathy 63 (ortholog); FOUND IN calyx of Held (ortholog); dendrite (ortholog); glutamatergic synapse (ortholog) | NW_004955514 | 359174 | 376916 | Chinchilla | 35 | description | gene, protein-coding, MODEL [RefSeq] |
| 8847074 | Cplx2 | complexin 2 | ENCODES a protein that exhibits calcium-dependent protein binding (ortholog); SNARE binding (ortholog); syntaxin-1 binding (ortholog); INVOLVED IN positive regulation of synaptic plasticity (ortholog); regulation of synaptic vesicle fusion to presynaptic active zone membrane (ortholog); synaptic ves icle exocytosis (ortholog); ASSOCIATED WITH bipolar disorder (ortholog); psychotic disorder (ortholog); schizophrenia (ortholog); FOUND IN calyx of Held (ortholog); dendrite (ortholog); glutamatergic synapse (ortholog) | NW_004955408 | 28308807 | 28388650 | Chinchilla | 21 | description | gene, protein-coding, MODEL [RefSeq] |
| 9000713 | Cylc2 | cylicin 2 | INVOLVED IN acrosome assembly (ortholog); maintenance of cell number (ortholog); manchette assembly (ortholog); FOUND IN cytoskeletal calyx (ortholog); perinuclear theca (ortholog); sperm glycocalyx (ortholog) | NW_004955419 | 23183700 | 23218555 | Chinchilla | 11 | description | gene, protein-coding, MODEL [RefSeq] |
| 8816544 | Git1 | GIT ArfGAP 1 | ENCODES a protein that exhibits gamma-tubulin binding (ortholog); GTPase activator activity (ortholog); identical protein binding (ortholog); INVOLVED IN brain development (ortholog); cell redox homeostasis (ortholog); cellular response to epidermal growth factor stimulus (ortholog); PARTICIPATES IN Arf family mediated signaling pathway; E-cadherin signaling pathway; ASSOCIATED WITH attention deficit hyperactivity disorder (ortholog); genetic disease (ortholog); Huntington's disease (ortholog); FOUND IN calyx of Held (ortholog); centrosome (ortholog); cytosol (ortholog) | NW_004955481 | 3671728 | 3681279 | Chinchilla | 73 | description | gene, protein-coding, MODEL [RefSeq] |
| 9033175 | Git2 | GIT ArfGAP 2 | ENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN behavioral response to pain (ortholog); regulation of synaptic vesicle exocytosis (ortholog); ASSOCIATED WITH inflammatory bowel disease (ortholog); FOUND IN calyx of Held (ortholog); nucleoplasm (ortholog); presynapse (ortholog) | NW_004955455 | 8611218 | 8669527 | Chinchilla | 17 | description | gene, protein-coding, MODEL [RefSeq] |
| 9049429 | Glra1 | glycine receptor alpha 1 | ENCODES a protein that exhibits extracellularly glycine-gated chloride channel activity (ortholog); extracellularly glycine-gated ion channel activity (ortholog); glycine binding (ortholog); INVOLVED IN acrosome reaction (ortholog); action potential (ortholog); adult walking behavior (ortholog); PAR TICIPATES IN Inhibitory synaptic transmission pathway; ASSOCIATED WITH dystonia (ortholog); epilepsy (ortholog); genetic disease (ortholog); FOUND IN calyx of Held (ortholog); endoplasmic reticulum (ortholog); external side of plasma membrane (ortholog) | NW_004955408 | 6236092 | 6333166 | Chinchilla | 87 | description | gene, protein-coding, MODEL [RefSeq] |
| 8943561 | Htr1b | 5-hydroxytryptamine receptor 1B | ENCODES a protein that exhibits G protein-coupled serotonin receptor activity (ortholog); Gi/o-coupled serotonin receptor activity (ortholog); heterocyclic compound binding (ortholog); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); adenylate cyclase -inhibiting serotonin receptor signaling pathway (ortholog); bone remodeling (ortholog); ASSOCIATED WITH alcohol dependence (ortholog); alcohol use disorder (ortholog); amphetamine abuse (ortholog); FOUND IN calyx of Held (ortholog); cytoplasm (ortholog); G protein-coupled serotonin receptor complex (ortholog) | NW_004955502 | 5640919 | 5646899 | Chinchilla | 74 | description | gene, protein-coding, MODEL [RefSeq] |
| 8873193 | Itsn1 | intersectin 1 | ENCODES a protein that exhibits kinase activator activity (ortholog); molecular adaptor activity (ortholog); proline-rich region binding (ortholog); INVOLVED IN cell-cell signaling (ortholog); endocytosis (ortholog); intracellular protein localization (ortholog); PARTICIPATES IN clathrin-dependent s ynaptic vesicle endocytosis; ephrin - ephrin receptor bidirectional signaling axis; ASSOCIATED WITH autistic disorder (ortholog); COVID-19 (ortholog); esophageal atresia/tracheoesophageal fistula (ortholog); FOUND IN apical dendrite (ortholog); calyx of Held (ortholog); clathrin-coated pit (ortholog) | NW_004955407 | 33056004 | 33275681 | Chinchilla | 68 | description | gene, protein-coding, MODEL [RefSeq] |
| 8944773 | Kcna3 | potassium voltage-gated channel subfamily A member 3 | ENCODES a protein that exhibits delayed rectifier potassium channel activity (ortholog); outward rectifier potassium channel activity (ortholog); voltage-gated potassium channel activity (ortholog); INVOLVED IN corpus callosum development (ortholog); optic nerve development (ortholog); potassium ion transmembrane transport (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy (ortholog); genetic disease (ortholog); hypertension (ortholog); FOUND IN axon (ortholog); calyx of Held (ortholog); glutamatergic synapse (ortholog) | NW_004955435 | 14132877 | 14148911 | Chinchilla | 42 | description | gene, protein-coding, MODEL [RefSeq] |
| 8952193 | Kcnc1 | potassium voltage-gated channel subfamily C member 1 | ENCODES a protein that exhibits delayed rectifier potassium channel activity (ortholog); kinesin binding (ortholog); transmembrane transporter binding (ortholog); INVOLVED IN cellular response to xenobiotic stimulus (ortholog); cerebellum development (ortholog); corpus callosum development (ortholog ); ASSOCIATED WITH Alzheimer's disease (ortholog); epilepsy (ortholog); genetic disease (ortholog); FOUND IN axolemma (ortholog); calyx of Held (ortholog); cell surface (ortholog) | NW_004955414 | 32538968 | 32580370 | Chinchilla | 57 | description | gene, protein-coding, MODEL [RefSeq] |
| 8745766 | Kcnc3 | potassium voltage-gated channel subfamily C member 3 | ENCODES a protein that exhibits voltage-gated potassium channel activity (ortholog); INVOLVED IN corpus callosum development (ortholog); cortical actin cytoskeleton organization (ortholog); optic nerve development (ortholog); ASSOCIATED WITH genetic disease (ortholog); spinocerebellar ataxia 13 (ort holog); FOUND IN axolemma (ortholog); axon terminus (ortholog); calyx of Held (ortholog) | NW_004955559 | 782842 | 795455 | Chinchilla | 32 | description | gene, protein-coding, MODEL [RefSeq] |
| 8975539 | Kcnc4 | potassium voltage-gated channel subfamily C member 4 | ENCODES a protein that exhibits voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential (ortholog); voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential (ortholog); voltage-gated potassium channel activ ity (ortholog); INVOLVED IN axon development (ortholog); cerebral cortex development (ortholog); corpus callosum development (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Hyperalgesia (ortholog); sciatic neuropathy (ortholog); FOUND IN axon (ortholog); axon terminus (ortholog); calyx of Held (ortholog) | NW_004955435 | 13728272 | 13750420 | Chinchilla | 38 | description | gene, protein-coding, MODEL [RefSeq] |
| 8836666 | Kcnq5 | potassium voltage-gated channel subfamily Q member 5 | ENCODES a protein that exhibits voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential (ortholog); voltage-gated potassium channel activity (ortholog); INVOLVED IN potassium ion transmembrane transport (ortholog); potassium ion transport (ortholog); AS SOCIATED WITH autosomal dominant intellectual developmental disorder (ortholog); autosomal dominant intellectual developmental disorder 46 (ortholog); congenital diaphragmatic hernia (ortholog); FOUND IN calyx of Held (ortholog); clathrin coat (ortholog); plasma membrane (ortholog) | NW_004955488 | 7406633 | 7928526 | Chinchilla | 28 | description | gene, protein-coding, MODEL [RefSeq] |
| 8924004 | Ncs1 | neuronal calcium sensor 1 | ENCODES a protein that exhibits calcium ion binding (ortholog); magnesium ion binding (ortholog); protein kinase binding (ortholog); INVOLVED IN positive regulation of calcium-mediated signaling (ortholog); positive regulation of exocytosis (ortholog); regulation of neuron projection development (or tholog); PARTICIPATES IN calcium/calcium-mediated signaling pathway; FOUND IN axon (ortholog); calyx of Held (ortholog); cytoplasm (ortholog) | NW_004955513 | 268979 | 289385 | Chinchilla | 28 | description | gene, protein-coding, MODEL [RefSeq] |
| 8758313 | Prkcb | protein kinase C beta | ENCODES a protein that exhibits calcium channel regulator activity (ortholog); calcium,diacylglycerol-dependent serine/threonine kinase activity (ortholog); chromatin binding (ortholog); INVOLVED IN B cell activation (ortholog); B cell receptor signaling pathway (ortholog); calcium ion transport (or tholog); PARTICIPATES IN insulin signaling pathway; interleukin-2 signaling pathway; protein kinase C (PKC) signaling pathway; ASSOCIATED WITH adult T-cell leukemia/lymphoma (ortholog); Alzheimer's disease (ortholog); autistic disorder (ortholog); FOUND IN brush border membrane (ortholog); calyx of Held (ortholog); centrosome (ortholog) | NW_004955493 | 2395494 | 2710522 | Chinchilla | 102 | description | gene, protein-coding, MODEL [RefSeq] |
| 8857853 | Prkcg | protein kinase C gamma | ENCODES a protein that exhibits calcium,diacylglycerol-dependent serine/threonine kinase activity (ortholog); protein kinase activity (ortholog); protein serine/threonine/tyrosine kinase activity (ortholog); INVOLVED IN chemical synaptic transmission (ortholog); chemosensory behavior (ortholog); inn ervation (ortholog); PARTICIPATES IN eicosanoid signaling pathway; endothelin signaling pathway; insulin signaling pathway; ASSOCIATED WITH Animal Disease Models (ortholog); autosomal dominant cerebellar ataxia (ortholog); autosomal recessive spinocerebellar ataxia 14 (ortholog); FOUND IN calyx of Held (ortholog); cell-cell junction (ortholog); cytoplasm (ortholog) | NW_004955604 | 262182 | 279259 | Chinchilla | 74 | description | gene, protein-coding, MODEL [RefSeq] |
| 9033587 | Rimbp2 | RIMS binding protein 2 | ENCODES a protein that exhibits protein-macromolecule adaptor activity (ortholog); structural constituent of presynaptic active zone (ortholog); voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels (ortholog); INVOLVED IN regulation of calcium-depende nt activation of synaptic vesicle fusion (ortholog); regulation of presynaptic membrane potential (ortholog); FOUND IN calyx of Held (ortholog); glutamatergic synapse (ortholog); presynaptic active zone cytoplasmic component (ortholog) | NW_004955482 | 1326628 | 1431358 | Chinchilla | 12 | description | gene, protein-coding, MODEL [RefSeq] |
| 8768375 | Syp | synaptophysin | ENCODES a protein that exhibits cholesterol binding (ortholog); identical protein binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN endocytosis (ortholog); modulation of chemical synaptic transmission (ortholog); protein homooligomerization (ortholog); ASSOCIATED WITH cochl ear disease; alcohol use disorder (ortholog); Alzheimer's disease (ortholog); FOUND IN basal part of cell; vestibular calyx terminal; excitatory synapse (ortholog) | NW_004955543 | 675294 | 689579 | Chinchilla | 74 | description | gene, protein-coding, MODEL [RefSeq] |
| 8843577 | Tprg1l | tumor protein p63 regulated 1 like | ENCODES a protein that exhibits calmodulin binding (ortholog); identical protein binding (ortholog); INVOLVED IN calcineurin-NFAT signaling cascade (ortholog); negative regulation of synaptic transmission (ortholog); regulation of synaptic transmission, glutamatergic (ortholog); FOUND IN caly ='font-weight:700;'>calyx of Held (ortholog); extrinsic component of synaptic vesicle membrane (ortholog); glutamatergic synapse (ortholog) | NW_004955486 | 8007678 | 8013996 | Chinchilla | 17 | description | gene, protein-coding, MODEL [RefSeq] |
| 8858992 | Tspoap1 | TSPO associated protein 1 | ENCODES a protein that exhibits benzodiazepine receptor binding (ortholog); voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels (ortholog); INVOLVED IN regulation of neurotransmitter secretion (ortholog); ASSOCIATED WITH Bardet-Biedl syndrome (orthol og); COVID-19 (ortholog); dystonia (ortholog); FOUND IN calyx of Held (ortholog); cytoplasm (ortholog); glutamatergic synapse (ortholog) | NW_004955451 | 4707440 | 4733179 | Chinchilla | 17 | description | gene, protein-coding, MODEL [RefSeq] |
| 9062927 | Unc13a | unc-13 homolog A | ENCODES a protein that exhibits calmodulin binding (ortholog); diacylglycerol binding (ortholog); identical protein binding (ortholog); INVOLVED IN amyloid-beta metabolic process (ortholog); dense core granule docking (ortholog); dense core granule priming (ortholog); PARTICIPATES IN insulin secreti on pathway; ASSOCIATED WITH amyotrophic lateral sclerosis type 1 (ortholog); autistic disorder (ortholog); cerebellar ataxia (ortholog); FOUND IN axon (ortholog); calyx of Held (ortholog); excitatory synapse (ortholog) | NW_004955524 | 725353 | 769745 | Chinchilla | 71 | description | gene, protein-coding, MODEL [RefSeq] |
| 9037059 | Unc13c | unc-13 homolog C | ENCODES a protein that exhibits calmodulin binding (ortholog); syntaxin binding (ortholog); syntaxin-1 binding (ortholog); INVOLVED IN chemical synaptic transmission (ortholog); negative regulation of synaptic plasticity (ortholog); synaptic vesicle exocytosis (ortholog); ASSOCIATED WITH clubfoot (o rtholog); FOUND IN calyx of Held (ortholog); parallel fiber to Purkinje cell synapse (ortholog); presynapse (ortholog) | NW_004955409 | 889912 | 1325136 | Chinchilla | 14 | description | gene, protein-coding, MODEL [RefSeq] |