Cplx2 (complexin 2) - Rat Genome Database

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Gene: Cplx2 (complexin 2) Chinchilla lanigera
Analyze
Symbol: Cplx2
Name: complexin 2
RGD ID: 8847074
Description: ENCODES a protein that exhibits calcium-dependent protein binding (ortholog); SNARE binding (ortholog); syntaxin-1 binding (ortholog); INVOLVED IN positive regulation of synaptic plasticity (ortholog); regulation of synaptic vesicle fusion to presynaptic active zone membrane (ortholog); synaptic vesicle exocytosis (ortholog); ASSOCIATED WITH bipolar disorder (ortholog); Ehlers-Danlos syndrome dermatosparaxis type (ortholog); genetic disease (ortholog); FOUND IN calyx of Held (ortholog); dendrite (ortholog); glutamatergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: complexin-2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540828,308,517 - 28,388,742 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540828,308,807 - 28,388,650 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Cplx2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540828,308,517 - 28,388,742 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540828,308,807 - 28,388,650 (+)NCBIChiLan1.0ChiLan1.0
CPLX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385175,796,533 - 175,884,021 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5175,796,310 - 175,884,021 (+)EnsemblGRCh38hg38GRCh38
GRCh375175,223,536 - 175,311,024 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365175,156,216 - 175,243,629 (+)NCBINCBI36Build 36hg18NCBI36
Build 345175,156,215 - 175,243,629NCBI
Celera5171,262,673 - 171,350,105 (+)NCBICelera
Cytogenetic Map5q35.2NCBI
HuRef5170,322,487 - 170,409,702 (+)NCBIHuRef
CHM1_15174,656,299 - 174,743,770 (+)NCBICHM1_1
T2T-CHM13v2.05176,340,215 - 176,427,717 (+)NCBIT2T-CHM13v2.0
Cplx2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391354,455,447 - 54,531,736 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1354,455,978 - 54,466,823 (+)EnsemblGRCm39 Ensembl
GRCm39 Ensembl1354,519,162 - 54,531,730 (+)EnsemblGRCm39 Ensembl
GRCm381354,301,964 - 54,383,923 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1354,371,349 - 54,383,917 (+)EnsemblGRCm38mm10GRCm38
MGSCv371354,472,713 - 54,485,278 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361354,380,974 - 54,393,539 (+)NCBIMGSCv36mm8
Celera1355,439,482 - 55,451,914 (+)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1328.59NCBI
Cplx2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81710,224,673 - 10,297,974 (-)NCBIGRCr8
mRatBN7.21710,219,577 - 10,292,835 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1710,222,347 - 10,293,855 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1710,237,601 - 10,245,934 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01711,770,838 - 11,779,143 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01710,234,026 - 10,242,359 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01710,756,871 - 10,828,811 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1710,756,285 - 10,818,835 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01712,880,802 - 12,952,180 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41716,314,592 - 16,322,938 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11716,314,591 - 16,322,938 (-)NCBI
Celera1710,295,626 - 10,303,931 (-)NCBICelera
Cytogenetic Map17p14NCBI
CPLX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24170,925,024 - 171,014,363 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15169,064,487 - 169,153,901 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05171,144,671 - 171,233,028 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15178,041,212 - 178,128,595 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5178,115,947 - 178,128,595 (+)Ensemblpanpan1.1panPan2
CPLX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1437,203,003 - 37,275,938 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl437,206,082 - 37,275,954 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha437,150,959 - 37,235,213 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0437,569,467 - 37,653,831 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1437,394,694 - 37,478,954 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0437,582,684 - 37,667,026 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0438,092,304 - 38,176,702 (-)NCBIUU_Cfam_GSD_1.0
Cplx2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213121,252,379 - 121,335,618 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936597348,203 - 357,997 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936597276,540 - 356,822 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CPLX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl281,732,533 - 81,813,271 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1281,732,527 - 81,813,189 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CPLX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12377,943,553 - 78,031,083 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2378,025,798 - 78,027,094 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666034557,841 - 646,727 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cplx2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473314,089,018 - 14,097,508 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473314,085,085 - 14,170,711 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000019878   ⟹   ENSCLAP00000019685
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540828,308,517 - 28,388,742 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000019879   ⟹   ENSCLAP00000019686
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540828,375,797 - 28,388,742 (+)Ensembl
RefSeq Acc Id: XM_005376364   ⟹   XP_005376421
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540828,376,329 - 28,388,650 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005376365   ⟹   XP_005376422
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540828,308,807 - 28,388,650 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005376421 (Get FASTA)   NCBI Sequence Viewer  
  XP_005376422 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000019685
  ENSCLAP00000019685.1
  ENSCLAP00000019686
  ENSCLAP00000019686.1
Reference Protein Sequences
RefSeq Acc Id: XP_005376422   ⟸   XM_005376365
- UniProtKB: A0A8C2YSB9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005376421   ⟸   XM_005376364
- UniProtKB: A0A8C2YSB9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000019686   ⟸   ENSCLAT00000019879
RefSeq Acc Id: ENSCLAP00000019685   ⟸   ENSCLAT00000019878


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000013505 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000019878 ENTREZGENE
  ENSCLAT00000019878.1 UniProtKB/TrEMBL
  ENSCLAT00000019879 ENTREZGENE
  ENSCLAT00000019879.1 UniProtKB/TrEMBL
Gene3D-CATH Single Helix bin UniProtKB/TrEMBL
InterPro Synaphin UniProtKB/TrEMBL
NCBI Gene Cplx2 ENTREZGENE
PANTHER COMPLEXIN-2 UniProtKB/TrEMBL
  PTHR16705 UniProtKB/TrEMBL
Pfam Synaphin UniProtKB/TrEMBL
Superfamily-SCOP SNARE fusion complex UniProtKB/TrEMBL
UniProt A0A8C2YSB9 ENTREZGENE, UniProtKB/TrEMBL