| 733285 | Ssb | small RNA binding exonuclease protection factor La | Enables RNA binding activity. Predicted to be involved in several processes, including IRES-dependent viral translational initiation; RNA metabolic process; and protein localization to cytoplasmic stress granule. Located in nucleus. Is expressed in several structures, including central nervous syste m; early conceptus; gonad; sensory organ; and spleen. Orthologous to human SSB (small RNA binding exonuclease protection factor La). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 69691963 | 69702185 | Mouse | 159 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1619953 | Spsb1 | splA/ryanodine receptor domain and SOCS box containing 1 | Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein ubiquitination. Predicted to be located in cytosol. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to hum an SPSB1 (splA/ryanodine receptor domain and SOCS box containing 1). [provided by Alliance of Genome Resources, Jul 2025] | 4 | 149980740 | 150039494 | Mouse | 174 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1620906 | Spsb2 | splA/ryanodine receptor domain and SOCS box containing 2 | This gene encodes a member of the SSB family of proteins that contain a central SPRY (repeats in splA and ryanodine receptors) domain and a C-terminal SOCS (suppressor of cytokine signaling) box. The encoded protein is an adaptor protein in the E3 ubiquitin liga se complex that ubiquitinates inducible nitric oxide synthase and targets it for proteasomal degradation. Mice lacking the encoded protein exhibit lower blood urea nitrogen levels and mild thrombocytopenia due to reduced platelet production. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015] | 6 | 124785640 | 124787582 | Mouse | 88 | description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1558086 | Spsb4 | splA/ryanodine receptor domain and SOCS box containing 4 | Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in several processes, including positive regulation of protein polyubiquitination; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Predicted to be located in cytosol. Predicted to be part of SCF ubiquitin ligase complex. Is expressed in cerebral cortex ventricular layer and cortical plate. Orthologous to human SPSB4 (splA/ryanodine receptor domain and SOCS box containing 4). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 96825535 | 96900408 | Mouse | 136 | old_gene_name , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 736465 | Ssbp1 | single-stranded DNA binding protein 1 | Predicted to enable several functions, including chromatin binding activity; protein homodimerization activity; and single-stranded DNA binding activity. Acts upstream of or within mitochondrion organization. Located in mitochondrion. Is expressed in brain ventricular layer; foregut; renal cortex; a nd submandibular gland primordium. Human ortholog(s) of this gene implicated in optic atrophy. Orthologous to human SSBP1 (single stranded DNA binding protein 1). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 40448302 | 40458757 | Mouse | 164 | symbol , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1614381 | Inip | INTS3 and NABP interacting protein | Predicted to be involved in double-strand break repair via homologous recombination; mitotic G2/M transition checkpoint; and response to ionizing radiation. Predicted to be located in nucleus and site of double-strand break. Predicted to be part of SOSS complex. Predicted to be active in nucleoplasm . Is expressed in several structures, including brain ventricular layer; submandibular gland primordium; thymus primordium; tooth; and vibrissa. Orthologous to human INIP (INTS3 and NABP interacting protein). [provided by Alliance of Genome Resources, Jul 2025] | 4 | 59769637 | 59783855 | Mouse | 90 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1615788 | Spsb3 | splA/ryanodine receptor domain and SOCS box containing 3 | Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in several processes, including negative regulation of cGAS/STING signaling pathway; negative regulation of epithelial to mesenchymal transition; and protein K48-linked ubiquitination. Predicted to be part of Cul5-RING ubiquitin ligase complex and SCF ubiquitin ligase complex. Predicted to be active in nucleus. Orthologous to human SPSB3 (splA/ryanodine receptor domain and SOCS box containing 3). [provided by Alliance of Genome Resources, Apr 2025] | 17 | 25104956 | 25111124 | Mouse | 96 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1558429 | Ssbp2 | single-stranded DNA binding protein 2 | Predicted to enable single-stranded DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in several structures, including adipose tissue; alimentary system; c entral nervous system; genitourinary system; and limb. Orthologous to human SSBP2 (single stranded DNA binding protein 2). [provided by Alliance of Genome Resources, Jul 2025] | 13 | 91608449 | 91854299 | Mouse | 169 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 736343 | Ssbp3 | single-stranded DNA binding protein 3 | This gene encodes a member of the Ssdp (sequence-specific single-stranded DNA binding protein) family of proteins. The encoded protein binds specifically to single-stranded pyrimidine-rich DNA elements. The encoded protein has been shown to be important for head development and may play a role in th e differentiation of spinal interneurons. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] | 4 | 106768667 | 106906891 | Mouse | 164 | symbol , PhenoGen | gene, protein-coding, REVIEWED [RefSeq] |
| 1557483 | Ssbp4 | single stranded DNA binding protein 4 | Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; gonad; limb; retina; and trunk somite. Orthologous to human SSBP4 (sin gle stranded DNA binding protein 4). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 71050135 | 71061084 | Mouse | 78 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1331947 | Nabp1 | nucleic acid binding protein 1 | Enables RNA binding activity and single-stranded DNA binding activity. Predicted to be involved in double-strand break repair via homologous recombination; mitotic G2/M transition checkpoint; and response to ionizing radiation. Located in chromosome, telomeric region and nucleus. Is expressed in sev eral structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human NABP1 (nucleic acid binding protein 1). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 51504127 | 51517634 | Mouse | 218 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1331927 | Nabp2 | nucleic acid binding protein 2 | Predicted to enable DNA polymerase binding activity and G-rich strand telomeric DNA binding activity. Involved in DNA repair and positive regulation of telomere capping. Located in chromosome, telomeric region. Is expressed in several structures, including genitourinary system; heart; liver; lung; a nd spleen. Orthologous to human NABP2 (nucleic acid binding protein 2). [provided by Alliance of Genome Resources, Jul 2025] | 10 | 128237263 | 128247426 | Mouse | 199 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1313129 | Smc2 | structural maintenance of chromosomes 2 | The protein encoded by this gene is a component of both condensin I and condensin II complexes, and forms a heterodimer with structural maintenance of chromosome 4 (Smc4). This heterodimer is the catalytic subunit for both condensin complexes, and is involved in several processes, including chromoso me condensation during mitosis and meiosis, cohesin removal during mitosis and meiosis, and single-strand break (SSB) repair. Reduced expression of this gene results in chromosome segregation defects during mitosis and meiosis, with a more severe defect observed in embryonic stem cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014] | 4 | 52438966 | 52488365 | Mouse | 212 | description | gene, protein-coding, REVIEWED [RefSeq] |