Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ssb | Mouse | (1->4)-beta-D-glucan | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SSB mRNA | CTD | PMID:36331819 | Ssb | Mouse | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of SSB mRNA | CTD | PMID:17555576 | Ssb | Mouse | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | EXP | | 6480464 | 2 more ... | CTD | PMID:30294300 | Ssb | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SSB mRNA | CTD | PMID:19770486 | Ssb | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Ssb (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SSB mRNA | CTD | PMID:32109520 and PMID:34747641 | Ssb | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of SSB mRNA | CTD | PMID:21570461 and PMID:24680724 | Ssb | Mouse | 2,3,7,8-Tetrachlorodibenzofuran | increases expression | ISO | Ssb (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:32109520 | Ssb | Mouse | 2,6-dinitrotoluene | affects expression | ISO | Ssb (Rattus norvegicus) | 6480464 | 2 and 6-dinitrotoluene affects the expression of SSB mRNA | CTD | PMID:21346803 | Ssb | Mouse | 2-amino-14,16-dimethyloctadecan-3-ol | decreases expression | ISO | SSB (Homo sapiens) | 6480464 | 2-amino-14 and 16-dimethyloctadecan-3-ol results in decreased expression of SSB protein | CTD | PMID:32044396 | Ssb | Mouse | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | SSB (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SSB mRNA | CTD | PMID:28628672 | Ssb | Mouse | 3H-1,2-dithiole-3-thione | decreases expression | ISO | Ssb (Rattus norvegicus) | 6480464 | 1 and 2-dithiol-3-thione results in decreased expression of SSB mRNA | CTD | PMID:19162173 | Ssb | Mouse | 4,4'-sulfonyldiphenol | multiple interactions | ISO | Ssb (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of SSB mRNA | CTD | PMID:36041667 | Ssb | Mouse | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of SSB mRNA | CTD | PMID:19770486 | Ssb | Mouse | aminoglutethimide | decreases expression | ISO | SSB (Homo sapiens) | 6480464 | Aminoglutethimide results in decreased expression of SSB protein | CTD | PMID:26102013 | Ssb | Mouse | ammonium chloride | affects expression | ISO | Ssb (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of SSB mRNA | CTD | PMID:16483693 | Ssb | Mouse | ammonium chloride | multiple interactions | ISO | SSB (Homo sapiens) | 6480464 | Ammonium Chloride inhibits the reaction [SSB protein results in increased expression of CXCL8 mRNA] and Ammonium Chloride inhibits the reaction [SSB protein results in increased secretion of CXCL8 protein] | CTD | PMID:25915936 | Ssb | Mouse | aristolochic acid A | multiple interactions | ISO | Ssb (Rattus norvegicus) | 6480464 | [aristolochic acid I co-treated with aristolochic acid II] results in decreased expression of SSB mRNA | CTD | PMID:23912714 | Ssb | Mouse | aristolochic acid A | decreases expression | ISO | SSB (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of SSB mRNA | CTD | PMID:33212167 | Ssb | Mouse | arsenous acid | decreases expression | ISO | SSB (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of SSB protein | CTD | PMID:25419056 | Ssb | Mouse | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of SSB mRNA | CTD | PMID:27858113 | Ssb | Mouse | benzo[b]fluoranthene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of SSB mRNA | CTD | PMID:27858113 | Ssb | Mouse | bisphenol A | increases expression | ISO | Ssb (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of SSB mRNA | CTD | PMID:25181051 | Ssb | Mouse | bisphenol A | decreases expression | ISO | SSB (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of SSB protein | CTD | PMID:34186270 and PMID:37567409 | Ssb | Mouse | bisphenol A | multiple interactions | ISO | Ssb (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of SSB mRNA | CTD | PMID:36041667 | Ssb | Mouse | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SSB mRNA | CTD | PMID:33221593 | Ssb | Mouse | Bisphenol B | increases expression | ISO | SSB (Homo sapiens) | 6480464 | bisphenol B results in increased expression of SSB protein | CTD | PMID:34186270 | Ssb | Mouse | bisphenol F | multiple interactions | ISO | SSB (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SSB mRNA | CTD | PMID:28628672 | Ssb | Mouse | bisphenol F | increases expression | ISO | SSB (Homo sapiens) | 6480464 | bisphenol F results in increased expression of SSB protein | CTD | PMID:34186270 | Ssb | Mouse | bisphenol F | multiple interactions | ISO | Ssb (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of SSB mRNA | CTD | PMID:36041667 | Ssb | Mouse | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of SSB mRNA | CTD | PMID:24982889 | Ssb | Mouse | caffeine | affects phosphorylation | ISO | SSB (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of SSB protein | CTD | PMID:35688186 | Ssb | Mouse | chloroquine | multiple interactions | ISO | SSB (Homo sapiens) | 6480464 | Chloroquine inhibits the reaction [SSB protein results in increased expression of CXCL8 mRNA] and Chloroquine inhibits the reaction [SSB protein results in increased secretion of CXCL8 protein] | CTD | PMID:25915936 | Ssb | Mouse | chlorpyrifos | decreases expression | EXP | | 6480464 | Chlorpyrifos results in decreased expression of SSB mRNA | CTD | PMID:32715474 and PMID:37019170 | Ssb | Mouse | chrysene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of SSB mRNA | CTD | PMID:27858113 | Ssb | Mouse | clofibric acid | affects expression | ISO | Ssb (Rattus norvegicus) | 6480464 | Clofibric Acid affects the expression of SSB mRNA | CTD | PMID:17602206 | Ssb | Mouse | cocaine | affects expression | ISO | Ssb (Rattus norvegicus) | 6480464 | Cocaine affects the expression of SSB mRNA | CTD | PMID:20187946 | Ssb | Mouse | coumarin | increases phosphorylation | ISO | SSB (Homo sapiens) | 6480464 | coumarin results in increased phosphorylation of SSB protein | CTD | PMID:35688186 | Ssb | Mouse | cyclosporin A | decreases expression | EXP | | 6480464 | Cyclosporine results in decreased expression of SSB mRNA | CTD | PMID:19770486 | Ssb | Mouse | DDE | increases expression | ISO | SSB (Homo sapiens) | 6480464 | Dichlorodiphenyl Dichloroethylene results in increased expression of SSB mRNA | CTD | PMID:38568856 | Ssb | Mouse | deguelin | increases expression | ISO | SSB (Homo sapiens) | 6480464 | deguelin results in increased expression of SSB mRNA | CTD | PMID:33512557 | Ssb | Mouse | dexamethasone | multiple interactions | ISO | SSB (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SSB mRNA | CTD | PMID:28628672 | Ssb | Mouse | diarsenic trioxide | decreases expression | ISO | SSB (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of SSB protein | CTD | PMID:25419056 | Ssb | Mouse | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of SSB mRNA | CTD | PMID:21266533 | Ssb | Mouse | dicrotophos | decreases expression | ISO | SSB (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of SSB mRNA | CTD | PMID:28302478 | Ssb | Mouse | diethylstilbestrol | decreases expression | ISO | SSB (Homo sapiens) | 6480464 | Diethylstilbestrol results in decreased expression of SSB mRNA | CTD | PMID:36621641 | Ssb | Mouse | disodium selenite | increases expression | ISO | SSB (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of SSB mRNA | CTD | PMID:18175754 | Ssb | Mouse | enzyme inhibitor | multiple interactions | ISO | SSB (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of SSB protein | CTD | PMID:23301498 | Ssb | Mouse | epoxiconazole | increases expression | EXP | | 6480464 | epoxiconazole results in increased expression of SSB mRNA | CTD | PMID:35436446 | Ssb | Mouse | ethyl methanesulfonate | decreases expression | ISO | SSB (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of SSB mRNA | CTD | PMID:23649840 | Ssb | Mouse | flutamide | increases expression | ISO | Ssb (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of SSB mRNA | CTD | PMID:24136188 | Ssb | Mouse | formaldehyde | decreases expression | ISO | SSB (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of SSB mRNA | CTD | PMID:23649840 | Ssb | Mouse | FR900359 | affects phosphorylation | ISO | SSB (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of SSB protein | CTD | PMID:37730182 | Ssb | Mouse | gentamycin | increases expression | ISO | Ssb (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of SSB mRNA | CTD | PMID:22061828 | Ssb | Mouse | hypochlorous acid | increases expression | EXP | | 6480464 | Hypochlorous Acid results in increased expression of SSB mRNA | CTD | PMID:19376150 | Ssb | Mouse | indometacin | multiple interactions | ISO | SSB (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SSB mRNA | CTD | PMID:28628672 | Ssb | Mouse | ivermectin | decreases expression | ISO | SSB (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of SSB protein | CTD | PMID:32959892 | Ssb | Mouse | methyl methanesulfonate | decreases expression | ISO | SSB (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of SSB mRNA | CTD | PMID:23649840 | Ssb | Mouse | paracetamol | decreases expression | ISO | SSB (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of SSB mRNA | CTD | PMID:22230336 | Ssb | Mouse | paracetamol | decreases expression | ISO | Ssb (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of SSB mRNA | CTD | PMID:33387578 | Ssb | Mouse | perfluorooctane-1-sulfonic acid | decreases expression | ISO | SSB (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of SSB mRNA | CTD | PMID:27153767 | Ssb | Mouse | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SSB mRNA | CTD | PMID:36331819 | Ssb | Mouse | phenobarbital | affects expression | EXP | | 6480464 | Phenobarbital affects the expression of SSB mRNA | CTD | PMID:23091169 | Ssb | Mouse | potassium dichromate | decreases expression | EXP | | 6480464 | Potassium Dichromate results in decreased expression of SSB mRNA | CTD | PMID:23608068 | Ssb | Mouse | resveratrol | multiple interactions | ISO | SSB (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of SSB mRNA | CTD | PMID:23557933 | Ssb | Mouse | SB 203580 | multiple interactions | ISO | SSB (Homo sapiens) | 6480464 | SB 203580 inhibits the reaction [SSB protein results in increased secretion of CXCL8 protein] | CTD | PMID:25915936 | Ssb | Mouse | sodium arsenite | decreases expression | ISO | Ssb (Rattus norvegicus) | 6480464 | sodium arsenite results in decreased expression of SSB mRNA | CTD | PMID:19072884 | Ssb | Mouse | sodium arsenite | decreases expression | ISO | SSB (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of SSB mRNA | CTD | PMID:38568856 | Ssb | Mouse | sodium fluoride | decreases expression | EXP | | 6480464 | Sodium Fluoride results in decreased expression of SSB protein | CTD | PMID:28918527 | Ssb | Mouse | succimer | multiple interactions | EXP | | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of SSB mRNA | CTD | PMID:21641980 | Ssb | Mouse | tamoxifen | affects expression | EXP | | 6480464 | Tamoxifen affects the expression of SSB mRNA | CTD | PMID:17555576 | Ssb | Mouse | tebufenpyrad | increases expression | ISO | SSB (Homo sapiens) | 6480464 | 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in increased expression of SSB mRNA | CTD | PMID:33512557 | Ssb | Mouse | testosterone enanthate | affects expression | ISO | SSB (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of SSB mRNA | CTD | PMID:17440010 | Ssb | Mouse | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of SSB mRNA | CTD | PMID:31919559 | Ssb | Mouse | tetraphene | decreases expression | EXP | | 6480464 | benz(a)anthracene results in decreased expression of SSB mRNA | CTD | PMID:26377693 | Ssb | Mouse | tetraphene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of SSB mRNA | CTD | PMID:27858113 | Ssb | Mouse | thioacetamide | increases expression | ISO | Ssb (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of SSB mRNA | CTD | PMID:34492290 | Ssb | Mouse | titanium dioxide | decreases methylation | EXP | | 6480464 | titanium dioxide results in decreased methylation of SSB gene | CTD | PMID:35295148 | Ssb | Mouse | trichloroethene | decreases expression | ISO | Ssb (Rattus norvegicus) | 6480464 | Trichloroethylene results in decreased expression of SSB mRNA | CTD | PMID:33387578 | Ssb | Mouse | triphenyl phosphate | affects expression | ISO | SSB (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of SSB mRNA | CTD | PMID:37042841 | Ssb | Mouse | vinclozolin | increases expression | ISO | Ssb (Rattus norvegicus) | 6480464 | vinclozolin results in increased expression of SSB mRNA | CTD | PMID:23034163 | |