| 11334 | Sp1 | trans-acting transcription factor 1 | Enables DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II and response to hydroperoxide. Acts upstream of or within several processes, including embryo development; hemopoiesis; and mRNA transcription by RNA polymerase II. Located in chromatin and nucleus. Is expressed in several structures, including central nervous system; early conceptus; epithelium; eye; and genitourinary system. Orthologous to human SP1 (Sp1 transcription factor). [provided by Alliance of Genome Resources, Jul 2025] | 15 | 102314751 | 102344839 | Mouse | 582 | symbol , old_gene_name , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 731483 | Hnrnpu | heterogeneous nuclear ribonucleoprotein U | Enables several functions, including RNA polymerase II C-terminal domain binding activity; lncRNA binding activity; and promoter-specific chromatin binding activity. Involved in several processes, including RNA localization to chromatin; cellular response to leukemia inhibitory factor; and regulatio n of gene expression. Acts upstream of or within with a positive effect on mRNA metabolic process. Acts upstream of or within several processes, including brown fat cell differentiation; cardiac muscle cell development; and erythrocyte differentiation. Located in inactive sex chromosome and nucleus. Part of ribonucleoprotein complex. Is expressed in several structures, including branchial arch; future brain; limb primordium; tail bud; and unsegmented mesenchyme. Used to study developmental and epileptic encephalopathy 54. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 54. Orthologous to human HNRNPU (heterogeneous nuclear ribonucleoprotein U). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 178148673 | 178170063 | Mouse | 463 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1551996 | P2ry13 | purinergic receptor P2Y, G-protein coupled 13 | Predicted to enable G protein-coupled purinergic nucleotide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Located in endoplasmic reticulum. Is expressed in immune system; intestine; male reproductive gland or organ; and skin. Orthologous to human P2RY13 (purinergic receptor P2Y13). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 59115313 | 59118303 | Mouse | 81 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 733375 | St14 | suppression of tumorigenicity 14 (colon carcinoma) | Enables serine-type endopeptidase activity. Involved in proteolysis. Acts upstream of or within epithelial cell morphogenesis involved in placental branching and neural tube closure. Located in external side of plasma membrane and extracellular space. Is expressed in several structures, including al imentary system; brain; early conceptus; genitourinary system; and sensory organ. Used to study Sjogren's syndrome. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 11. Orthologous to human ST14 (ST14 transmembrane serine protease matriptase). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 30999886 | 31043138 | Mouse | 293 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 39128668 | Gm57553 | predicted gene, 57553 | | 1 | 92929596 | 92932762 | Mouse | | old_gene_name | gene, pseudo, MODEL [RefSeq] |
| 1322409 | Med17 | mediator complex subunit 17 | Predicted to enable nuclear thyroid hormone receptor binding activity and transcription coactivator activity. Predicted to contribute to ubiquitin protein ligase activity. Acts upstream of or within somatic stem cell population maintenance. Part of mediator complex. Is expressed in genitourinary sys tem and limb mesenchyme. Human ortholog(s) of this gene implicated in infantile cerebral and cerebellar atrophy with postnatal progressive microcephaly. Orthologous to human MED17 (mediator complex subunit 17). [provided by Alliance of Genome Resources, Apr 2025] | 9 | 15171647 | 15194576 | Mouse | 99 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1316996 | Med23 | mediator complex subunit 23 | Predicted to contribute to ubiquitin protein ligase activity. Acts upstream of or within positive regulation of T cell extravasation and positive regulation of gene expression. Part of mediator complex. Is expressed in several structures, including genitourinary system; tibialis anterior; and tongue . Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 18. Orthologous to human MED23 (mediator complex subunit 23). [provided by Alliance of Genome Resources, Apr 2025] | 10 | 24745889 | 24789358 | Mouse | 158 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1557558 | Med26 | mediator complex subunit 26 | Predicted to enable transcription coregulator activity. Predicted to be involved in positive regulation of gene expression and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of core mediator complex and mediator complex. Is expressed in sev eral structures, including central nervous system; limb; retina; and tongue. Orthologous to human MED26 (mediator complex subunit 26). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 73248402 | 73302154 | Mouse | 90 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1623965 | Med27 | mediator complex subunit 27 | Predicted to enable transcription coactivator activity. Predicted to contribute to ubiquitin protein ligase activity. Acts upstream of or within somatic stem cell population maintenance. Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be part of core mediator complex; me diator complex; and ubiquitin ligase complex. Is expressed in genitourinary system and tibialis anterior. Orthologous to human MED27 (mediator complex subunit 27). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 29236822 | 29414802 | Mouse | 109 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1321086 | Med7 | mediator complex subunit 7 | Predicted to enable transcription coregulator activity. Predicted to contribute to ubiquitin protein ligase activity. Acts upstream of or within somatic stem cell population maintenance. Part of mediator complex. Is expressed in cerebral cortex; genitourinary system; and tibialis anterior. Orthologo us to human MED7 (mediator complex subunit 7). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 46327742 | 46333548 | Mouse | 94 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1617593 | Med14 | mediator complex subunit 14 | Predicted to enable transcription coactivator activity. Acts upstream of or within somatic stem cell population maintenance. Part of mediator complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human MED14 (mediator complex subunit 14). [provided by Alliance of Genome Resources, Jul 2025] | X | 12541607 | 12628813 | Mouse | 107 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1558598 | Sp100 | nuclear antigen Sp100 | Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; chromo shadow domain binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including innate immune response; regulation of DNA-tem plated transcription; and regulation of signal transduction. Predicted to be located in cytoplasm and nuclear lumen. Predicted to be part of Mre11 complex. Is expressed in eye; olfactory placode; and otic pit. Orthologous to human SP100 (SP100 nuclear antigen). [provided by Alliance of Genome Resources, Apr 2025] | 1 | 85577683 | 85637719 | Mouse | 167 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1320920 | Sp110 | Sp110 nuclear body protein | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Acts upstream of or within positive regulation of apoptotic process and response to bacterium. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in central nervous system; early conceptus; genitourinary system; and thymus primordium. Human ortholog(s) of this gene implicated in hepatic venoocclusive disease with immunodeficiency and tuberculosis. Orthologous to human SP110 (SP110 nuclear body protein). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 85498462 | 85538571 | Mouse | 103 | symbol , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1621872 | Sp140 | Sp140 nuclear body protein | Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in fibrillar center and mitochondrion. Predicted to be active in nucleus. Orthologous to human ... (more) an style='font-weight:700;'>SP140 (SP140 nuclear body protein) and SP140L (SP140 nuclear body protein like). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 85515212 | 85572761 | Mouse | 58 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1621186 | Sp140l1 | Sp140 nuclear body protein like 1 | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in fibrillar center and mitochondrion. Predicted to be active in nucleus. [provided by Alliance of Genome R esources, Apr 2025] | 1 | 85065860 | 85088016 | Mouse | 5 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1613879 | Sp140l2 | Sp140 nuclear body protein like 2 | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in fibrillar center and mitochondrion. Predicted to be active in nucleus. [provided by Alliance of Genome R esources, Apr 2025] | 1 | 85219007 | 85260602 | Mouse | 4 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 617252031 | Sp100-rs | uncharacterized LOC546065 | | | | | Mouse | | symbol , PhenoGen | gene, protein-coding |
| 1608152 | Sp100-rs1 | nuclear antigen Sp100, related sequence 1 | | | | | Mouse | | symbol , PhenoGen , name | gene, protein-coding |
| 39128921 | Sp110-ps1 | Sp110 nuclear body protein, pseudogene 1 | Predicted to be located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025] | 1 | 85250516 | 85254756 | Mouse | | symbol , old_gene_name , PhenoGen , name | gene, pseudo, MODEL [RefSeq] |
| 2306402 | Sp110-ps2 | Sp110 nuclear body protein, pseudogene 2 | Predicted to be located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025] | 5 | 137718613 | 137720254 | Mouse | | symbol , PhenoGen , name | gene, pseudo, INFERRED [RefSeq] |
| 11131 | Ppia | peptidylprolyl isomerase A | Enables integrin binding activity and peptidyl-prolyl cis-trans isomerase activity. Involved in platelet aggregation. Acts upstream of or within neuron differentiation. Located in extracellular space. Is expressed in several structures, including early conceptus; gonad; hemolymphoid system gland; li ver; and skeletal muscle. Human ortholog(s) of this gene implicated in cholangiocarcinoma and human immunodeficiency virus infectious disease. Orthologous to human PPIA (peptidylprolyl isomerase A). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 6365867 | 6369817 | Mouse | 334 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 731295 | Spa17 | sperm autoantigenic protein 17 | Predicted to enable calmodulin binding activity. Predicted to act upstream of or within binding activity of sperm to zona pellucida. Located in several cellular components, including external side of plasma membrane; neuron projection; and sperm flagellum. Is expressed in several structures, includi ng brain; gonad; heart; hemolymphoid system gland; and lung. Orthologous to human SPA17 (sperm autoantigenic protein 17). [provided by Alliance of Genome Resources, Apr 2025] | 9 | 37514590 | 37525018 | Mouse | 125 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1620810 | Ccdc54 | coiled-coil domain containing 54 | Orthologous to human CCDC54 (coiled-coil domain containing 54). [provided by Alliance of Genome Resources, Jul 2025] | 16 | 50410222 | 50411517 | Mouse | 13 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1323517 | Cdadc1 | cytidine and dCMP deaminase domain containing 1 | Predicted to enable several functions, including deaminase activity; importin-alpha family protein binding activity; and protein homodimerization activity. Predicted to be involved in DNA cytosine deamination and cytidine deamination. Predicted to be located in nucleus. Predicted to be active in cyt oplasm. Orthologous to human CDADC1 (cytidine and dCMP deaminase domain containing 1). [provided by Alliance of Genome Resources, Apr 2025] | 14 | 59796837 | 59835433 | Mouse | 93 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1557138 | Ctnnbl1 | catenin, beta like 1 | Predicted to enable enzyme binding activity. Predicted to be involved in positive regulation of apoptotic process and somatic diversification of immunoglobulins. Predicted to act upstream of or within apoptotic process. Predicted to be located in centrosome; cytosol; and nucleoplasm. Predicted to be part of Prp19 complex and spliceosomal complex. Is expressed in cerebral cortex ventricular layer; embryo; limb; and limb mesenchyme. Human ortholog(s) of this gene implicated in colorectal cancer; immunodeficiency 99; and morbid obesity. Orthologous to human CTNNBL1 (catenin beta like 1). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 157579321 | 157733823 | Mouse | 113 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1623697 | Garin1b | golgi associated RAB2 interactor 1B | Involved in acrosome assembly and acrosome reaction. Located in Golgi apparatus. Orthologous to human GARIN1B (golgi associated RAB2 interactor 1B). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 29313468 | 29336021 | Mouse | 66 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1557863 | Rfx4 | regulatory factor X, 4 (influences HLA class II expression) | Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including central nervous system development; negative regulation of smoothen ed signaling pathway; and regulation of gene expression. Located in nucleus. Is expressed in several structures, including central nervous system; eye; future brain; genitourinary system; and liver. Orthologous to human RFX4 (regulatory factor X4). [provided by Alliance of Genome Resources, Jul 2025] | 10 | 84591895 | 84742402 | Mouse | 131 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1557391 | Spata16 | spermatogenesis associated 16 | Involved in spermatid development. Acts upstream of or within spermatogenesis. Predicted to be located in acrosomal vesicle. Predicted to be active in Golgi apparatus. Used to study male infertility. Human ortholog(s) of this gene implicated in spermatogenic failure 6. Orthologous to human SPATA16 ( spermatogenesis associated 16). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 26691769 | 27037398 | Mouse | 45 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1615317 | Gm7609 | predicted pseudogene 7609 | This gene is one of several duplicated genes in a repeat cluster in the homogeneously staining region (HSR) of chromosome 1. It is an Sp100-rs gene copy, which arose by duplication following the fusion of the Csprs (component of Sp1 100-rs) gene and the 5' part of the Sp100 (nuclear antigen Sp100) gene. The coding sequence of this gene is intact compared to that of the Csprs gene, and therefore NCBI represents this as a protein-coding gene. However, it is also possible to interpret this fusion gene as a pseudogene of the Sp100 gene. It is unknown if this gene produces a protein in vivo. [provided by RefSeq, Mar 2011] | 1 | 85177313 | 85193119 | Mouse | 12 | old_gene_name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 736536 | Ces2c | carboxylesterase 2C | This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and ch olesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. The transcription of this gene is regulated by several factors including HNF-4alpha (hepatocyte nuclear factor-4alpha), Sp1 (specificity protein 1), Sp3 and USF1 (upstream stimulatory factor 1). The expression and activity of this gene is age-related but independent of growth hormone level. This gene is clustered with several family members including a few of pseudogenes and Ces5 on chromosome 8.[provided by RefSeq, Jun 2010] | 8 | 105573700 | 105581115 | Mouse | 109 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1321957 | Csprs | component of Sp100-rs | Predicted to be located in nucleus. Orthologous to human SP100 (SP100 nuclear antigen). [provided by Alliance of Genome Resources, Apr 2025] | | | | Mouse | 59 | name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1319819 | Sp3 | trans-acting transcription factor 3 | This gene product belongs to a family of Sp1 related transcription factors, which regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivatio n domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses transcription of numerous genes. Alternative splicing results in transcript variants encoding different isoforms, and one variant initiates translation from a non-AUG (AUA) codon. [provided by RefSeq, Jul 2008] | 2 | 72766774 | 72810790 | Mouse | 257 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1615333 | Gm7592 | predicted gene 7592 | Orthologous to human GPR148 (G protein-coupled receptor 148). [provided by Alliance of Genome Resources, Apr 2025] | 1 | 85304553 | 85483402 | Mouse | 14 | old_gene_name , ensembl_full_name | gene, protein-coding, VALIDATED [RefSeq] |
| 39131243 | LOC100039029 | component of Sp100-rs-like | | | | | Mouse | | name | gene, protein-coding, MODEL [RefSeq] |
| 39130765 | LOC101055663 | component of Sp100-rs-like | | | | | Mouse | | name | gene, protein-coding, MODEL [RefSeq] |
| 39130037 | LOC102636558 | component of Sp100-rs-like | | | | | Mouse | | name | gene, protein-coding, MODEL [RefSeq] |
| 39128312 | LOC671917 | component of Sp100-rs-like | | | | | Mouse | | name | gene, protein-coding, MODEL [RefSeq] |
| 39128541 | LOC100040974 | sp110 nuclear body protein-like | | | | | Mouse | | name | gene, pseudo, MODEL [RefSeq] |
| 39128672 | LOC100041057 | nuclear body protein SP140-like | | | | | Mouse | | name | gene, protein-coding, MODEL [RefSeq] |
| 39130807 | LOC101055672 | nuclear body protein SP140-like | | | | | Mouse | | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 39129982 | LOC102633548 | sp110 nuclear body protein-like | | | | | Mouse | | name | gene, pseudo, MODEL [RefSeq] |
| 39129423 | LOC102633783 | sp110 nuclear body protein-like | | | | | Mouse | | name | gene, protein-coding, VALIDATED [RefSeq] |
| 39131042 | LOC102638047 | sp110 nuclear body protein-like | | | | | Mouse | | name | gene, protein-coding, VALIDATED [RefSeq] |
| 39129236 | LOC105242404 | sp110 nuclear body protein-like | | | | | Mouse | | name | gene, protein-coding, MODEL [RefSeq] |
| 39129504 | LOC115486430 | sp110 nuclear body protein-like | | | | | Mouse | | name | gene, pseudo, MODEL [RefSeq] |
| 39128655 | LOC118567365 | sp110 nuclear body protein-like | | | | | Mouse | | name | gene, pseudo, MODEL [RefSeq] |
| 39128803 | LOC118568473 | sp110 nuclear body protein-like | | | | | Mouse | | name | gene, protein-coding, MODEL [RefSeq] |
| 39128521 | LOC118568475 | nuclear body protein SP140-like | | | | | Mouse | | name | gene, protein-coding, MODEL [RefSeq] |
| 39129995 | LOC677525 | sp110 nuclear body protein-like | | | | | Mouse | | name | gene, protein-coding, MODEL [RefSeq] |
| 39128985 | LOC100041034 | Sp110 nuclear body protein pseudogene | | | | | Mouse | | name | gene, pseudo, VALIDATED [RefSeq] |
| 39128863 | LOC664787 | Sp110 nuclear body protein pseudogene | | | | | Mouse | | name | gene, pseudo, VALIDATED [RefSeq] |
| 39130349 | LOC100041708 | nuclear body protein SP140-like protein | | | | | Mouse | | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 39128445 | LOC108167387 | nuclear body protein SP140-like protein | | | | | Mouse | | name | gene, protein-coding, MODEL [RefSeq] |
| 39129412 | LOC118568468 | nuclear body protein SP140-like protein | | | | | Mouse | | name | gene, protein-coding, MODEL [RefSeq] |
| 1553779 | Sec11a | SEC11 homolog A, signal peptidase complex subunit | Predicted to enable serine-type endopeptidase activity. Predicted to be involved in signal peptide processing. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of signal peptidase complex. Is expressed in several structures, including alimentary system; cranium; genito urinary system; integumental system; and nervous system. Orthologous to human SEC11A (SEC11 homolog A, signal peptidase complex subunit). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 80565125 | 80597295 | Mouse | 86 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 2308286 | Gm2619 | predicted gene 2619 | | 1 | 85291128 | 85305100 | Mouse | | old_gene_name | gene, pseudo, VALIDATED [RefSeq] |
| 10029803 | Gm38510 | predicted gene, 38510 | | 1 | 85132922 | 85286736 | Mouse | | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 39131152 | Gm53567 | predicted gene, 53567 | | 1 | 85257384 | 85267618 | Mouse | | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18187808 | Gm55258 | predicted gene, 55258 | | | | | Mouse | | old_gene_name | gene, unprocessed_pseudogene |