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Genes search result for Homo sapiens
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64 records found for search term Usp1
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1315093USP1ubiquitin specific peptidase 1This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The prot16243639562451804Human129symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1347511WDR48WD repeat domain 48The protein encoded by this gene has been shown to interact with ubiquitin specific peptidase 1 (USP1), activating the deubiquitinating activity of USP1 and allowing it to remove the ubiquitin moiety from monoubiquitinated F33905201639096664Human97old_gene_name , descriptiongene, protein-coding, REVIEWED [RefSeq]
1352341USP10ubiquitin specific peptidase 10Ubiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and degradation. This gene encodes a member of the ubiquitin-specific protease family of cysteine proteases. The enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein subs168470000084779922Human151symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1347156USP11ubiquitin specific peptidase 11Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cyX4723300947248328Human105symbol , COSMIC , Human Proteome Mapgene, protein-coding, VALIDATED [RefSeq]
1317587USP12ubiquitin specific peptidase 12Enables cysteine-type deubiquitinase activity and cysteine-type endopeptidase activity. Involved in protein deubiquitination. Located in cytoplasm; nucleus; and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]132706615627171811Human112symbol , COSMIC , Human Proteome Map , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1314436USP13ubiquitin specific peptidase 13Enables several functions, including BAT3 complex binding activity; peptidase activity; and proteasome binding activity. Involved in several processes, including maintenance of unfolded protein; regulation of DNA-templated transcription; and regulation of catabolic process. Acts upstream of or withi3179653040179789401Human138symbol , COSMIC , Human Proteome Mapgene, protein-coding, VALIDATED [RefSeq]
1323483USP14ubiquitin specific peptidase 14This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice wit18158557214629Human157symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
733296USP15ubiquitin specific peptidase 15This gene encodes a member of the ubiquitin specific protease (USP) family of deubiquitinating enzymes. USP enzymes play critical roles in ubiquitin-dependent processes through polyubiquitin chain disassembly and hydrolysis of ubiquitin-substrate bonds. The encoded protein associates with the COP9 s126226040462416389Human171symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1316236USP16ubiquitin specific peptidase 16This gene encodes a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase/anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant form of the protein was shown to block cel212902466829054488Human120symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1353279USP18ubiquitin specific peptidase 18The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus, and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like221815017018177397Human261symbol , COSMIC , Human Proteome Mapgene, protein-coding, VALIDATED [RefSeq]
1344113USP19ubiquitin specific peptidase 19Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cy34910805049120823Human92symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1348071USP10P1USP10 pseudogene 1141967775019680942Humansymbol , GTEx , COSMIC , name , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
1604853USP10P2USP10 pseudogene 2141863411818637315Humansymbol , GTEx , COSMIC , name , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
38625153USP10P3USP10 pseudogene 3221556117515564363Humansymbol , GTEx , COSMIC , name , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
1346185USP12P1USP12 pseudogene 15171251643171253966Humansymbol , GTEx , COSMIC , name , Human Proteome Map , old_gene_symbolgene, pseudo, INFERRED [RefSeq]
14995390USP12P2USP12 pseudogene 22148295405148296664Humansymbol , old_gene_name , COSMIC , name , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
14995370USP12P3USP12 pseudogene 396708774667088288Humansymbol , GTEx , COSMIC , name , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
1351911USP12PXUSP12 pseudogene X-linkedINTERACTS WITH lipopolysaccharide; S-(1,2-dichlorovinyl)-L-cysteineX9011247590115029Human3symbol , COSMIC , name , Human Proteome Map , old_gene_symbolgene, pseudo, INFERRED [RefSeq]
1343926USP12PYUSP12 pseudogene Y-linkedINTERACTS WITH lipopolysaccharide; S-(1,2-dichlorovinyl)-L-cysteineY36825873685142Human3symbol , COSMIC , name , Human Proteome Map , old_gene_symbolgene, pseudo, INFERRED [RefSeq]
3029324USP17L1ubiquitin specific peptidase 17 like family member 1Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in regulation of apoptotic process and regulation of protein stability. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Jul 873323877333979Human21symbol , COSMIC , Human Proteome Map , old_gene_symbolgene, protein-coding, INFERRED [RefSeq]
1605214USP17L2ubiquitin specific peptidase 17 like family member 2Enables cysteine-type deubiquitinase activity. Involved in several processes, including CAAX-box protein processing; protein deubiquitination; and regulation of defense response. Located in endoplasmic reticulum membrane and nucleus. [provided by Alliance of Genome Resources, Jul 2025]81213643512138849Human54symbol , COSMIC , Human Proteome Map , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
2312705USP17L3ubiquitin specific peptidase 17 like family member 3Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in regulation of apoptotic process and regulation of protein stability. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Jul 879763937977985Human19symbol , COSMIC , Human Proteome Map , old_gene_symbolgene, protein-coding, INFERRED [RefSeq]
2312696USP17L4ubiquitin specific peptidase 17 like family member 4Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in regulation of apoptotic process and regulation of protein stability. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Jul 873371157338707Human13symbol , COSMIC , Human Proteome Mapgene, protein-coding, INFERRED [RefSeq]
2800946USP17L5ubiquitin specific peptidase 17 like family member 5Predicted to enable cysteine-type deubiquitinase activity and lncRNA binding activity. Predicted to be involved in regulation of apoptotic process and regulation of protein stability. Predicted to act upstream of or within protein deubiquitination. Predicted to be located in endoplasmic reticulum. P493394039340995Human33symbol , COSMIC , Human Proteome Mapgene, protein-coding, INFERRED [RefSeq]
2312702USP17L7ubiquitin specific peptidase 17 like family member 7Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in regulation of apoptotic process and regulation of protein stability. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Jul 81213241712134099Human16symbol , COSMIC , Human Proteome Mapgene, protein-coding, INFERRED [RefSeq]
2312703USP17L8ubiquitin specific peptidase 17 like family member 8Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in regulation of apoptotic process and regulation of protein stability. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Jul 879716617973253Human13symbol , COSMIC , Human Proteome Map , old_gene_symbolgene, protein-coding, INFERRED [RefSeq]
6481278USP12-DTUSP12 divergent transcriptINTERACTS WITH lipopolysaccharide; S-(1,2-dichlorovinyl)-L-cysteine132717225927183503Human3symbol , old_gene_name , COSMIC , name , Human Proteome Map , old_gene_symbolgene, ncrna, VALIDATED [RefSeq]
6904251USP17L10ubiquitin specific peptidase 17 like family member 10Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in regulation of apoptotic process and regulation of protein stability. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Jul 492106579212249Human20symbol , COSMIC , Human Proteome Mapgene, protein-coding, INFERRED [RefSeq]
6904258USP17L11ubiquitin specific peptidase 17 like family member 11Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in regulation of apoptotic process and regulation of protein stability. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Jul 492154059216997Human19symbol , COSMIC , Human Proteome Mapgene, protein-coding, INFERRED [RefSeq]
6904255USP17L12ubiquitin specific peptidase 17 like family member 12Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in regulation of apoptotic process and regulation of protein stability. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Jul 492201529221744Human19symbol , COSMIC , Human Proteome Mapgene, protein-coding, INFERRED [RefSeq]
6904261USP17L13ubiquitin specific peptidase 17 like family member 13Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in regulation of apoptotic process and regulation of protein stability. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Jul 492248969226488Human19symbol , COSMIC , Human Proteome Mapgene, protein-coding, INFERRED [RefSeq]
6904328USP17L15ubiquitin specific peptidase 17 like family member 15Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in regulation of apoptotic process and regulation of protein stability. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Jul 492343859236046Human25symbol , COSMIC , Human Proteome Mapgene, protein-coding, INFERRED [RefSeq]
6904267USP17L17ubiquitin specific peptidase 17 like family member 17Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in regulation of apoptotic process and regulation of protein stability. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Jul 492438799245471Human22symbol , COSMIC , Human Proteome Mapgene, protein-coding, INFERRED [RefSeq]
6904270USP17L18ubiquitin specific peptidase 17 like family member 18Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in regulation of apoptotic process and regulation of protein stability. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Jul 492486309250222Human21symbol , COSMIC , Human Proteome Mapgene, protein-coding, INFERRED [RefSeq]
6904287USP17L19ubiquitin specific peptidase 17 like family member 19Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in regulation of apoptotic process and regulation of protein stability. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Jul 492533789254970Human19symbol , COSMIC , Human Proteome Mapgene, protein-coding, INFERRED [RefSeq]
6904284USP17L20ubiquitin specific peptidase 17 like family member 20Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in regulation of apoptotic process and regulation of protein stability. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Jul 492581249259716Human19symbol , COSMIC , Human Proteome Mapgene, protein-coding, PROVISIONAL [RefSeq]
6904281USP17L21ubiquitin specific peptidase 17 like family member 21Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in regulation of apoptotic process and regulation of protein stability. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Jul 492628729264464Human20symbol , COSMIC , Human Proteome Mapgene, protein-coding, INFERRED [RefSeq]
6904427USP17L22ubiquitin specific peptidase 17 like family member 22Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in regulation of apoptotic process and regulation of protein stability. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Jul 492676199269211Human20symbol , COSMIC , Human Proteome Mapgene, protein-coding, INFERRED [RefSeq]
15036977USP17L23ubiquitin specific peptidase 17 like family member 23Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in protein deubiquitination. Predicted to be located in endoplasmic reticulum and nucleus. [provided by Alliance of Genome Resources, Jul 2025]Human7symbol , COSMIC , Human Proteome Mapgene, protein-coding
6904303USP17L24ubiquitin specific peptidase 17 like family member 24Enables RNA binding activity; cysteine-type deubiquitinase activity; and hyaluronic acid binding activity. Involved in positive regulation of epithelial cell apoptotic process and protein deubiquitination involved in ubiquitin-dependent protein catabolic process. Located in nucleolus. [provided by A493251659326757Human29symbol , COSMIC , Human Proteome Map , old_gene_symbolgene, protein-coding, INFERRED [RefSeq]
6904300USP17L25ubiquitin specific peptidase 17 like family member 25Enables RNA binding activity; cysteine-type deubiquitinase activity; and hyaluronic acid binding activity. Involved in positive regulation of epithelial cell apoptotic process and protein deubiquitination involved in ubiquitin-dependent protein catabolic process. Located in nucleolus. [provided by A493299119331503Human31symbol , COSMIC , Human Proteome Mapgene, protein-coding, INFERRED [RefSeq]
6904297USP17L26ubiquitin specific peptidase 17 like family member 26Enables RNA binding activity; cysteine-type deubiquitinase activity; and hyaluronic acid binding activity. Involved in positive regulation of epithelial cell apoptotic process and protein deubiquitination involved in ubiquitin-dependent protein catabolic process. Located in nucleolus. [provided by A493346589336250Human29symbol , COSMIC , Human Proteome Mapgene, protein-coding, INFERRED [RefSeq]
6904294USP17L27ubiquitin specific peptidase 17 like family member 27Enables RNA binding activity; cysteine-type deubiquitinase activity; and hyaluronic acid binding activity. Involved in positive regulation of epithelial cell apoptotic process and protein deubiquitination involved in ubiquitin-dependent protein catabolic process. Located in nucleolus. [provided by A493441489345740Human29symbol , COSMIC , Human Proteome Mapgene, protein-coding, INFERRED [RefSeq]
6904277USP17L28ubiquitin specific peptidase 17 like family member 28Enables RNA binding activity; cysteine-type deubiquitinase activity; and hyaluronic acid binding activity. Involved in positive regulation of epithelial cell apoptotic process and protein deubiquitination involved in ubiquitin-dependent protein catabolic process. Located in nucleolus. [provided by A493488939350485Human29symbol , COSMIC , Human Proteome Mapgene, protein-coding, INFERRED [RefSeq]
6904274USP17L29ubiquitin specific peptidase 17 like family member 29Enables RNA binding activity; cysteine-type deubiquitinase activity; and hyaluronic acid binding activity. Involved in positive regulation of epithelial cell apoptotic process and protein deubiquitination involved in ubiquitin-dependent protein catabolic process. Located in nucleolus. [provided by A493536389355230Human27symbol , COSMIC , Human Proteome Mapgene, protein-coding, INFERRED [RefSeq]
6904290USP17L30ubiquitin specific peptidase 17 like family member 30Enables RNA binding activity; cysteine-type deubiquitinase activity; and hyaluronic acid binding activity. Involved in positive regulation of epithelial cell apoptotic process and protein deubiquitination involved in ubiquitin-dependent protein catabolic process. Located in nucleolus. [provided by A493631299364721Human30symbol , COSMIC , Human Proteome Mapgene, protein-coding, INFERRED [RefSeq]
2793512USP17L6Pubiquitin specific peptidase 17 like family member 6, pseudogeneEnables cysteine-type deubiquitinase activity. Involved in protein deubiquitination involved in ubiquitin-dependent protein catabolic process. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Jul 2025]493678749369070Human42symbol , COSMIC , Human Proteome Map , old_gene_symbolgene, pseudo, VALIDATED [RefSeq]
1349777USP17L9Pubiquitin specific peptidase 17 like family member 9, pseudogeneINTERACTS WITH butanal; cadmium atom; copper(II) sulfate493583829359974Human5symbol , COSMIC , Human Proteome Map , old_gene_symbolgene, pseudo, VALIDATED [RefSeq]
6481274USP12-AS1USP12 antisense RNA 1INTERACTS WITH aflatoxin B1132712553327169135Human1symbol , COSMIC , name , Human Proteome Map , old_gene_symbolgene, ncrna, VALIDATED [RefSeq]
6904264USP17L14Pubiquitin specific peptidase 17 like family member 14, pseudogene492296419231233Humansymbol , COSMIC , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
6904265USP17L16Pubiquitin specific peptidase 17 like family member 16, pseudogene492392329240254Humansymbol , COSMIC , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
1349681USP21ubiquitin specific peptidase 21This gene encodes a member of the C19 peptidase family, also known as family 2 of ubiquitin carboxy-terminal hydrolases. The encoded protein cleaves ubiquitin from ubiquitinated proteins for recycling in intracellular protein degradation. The encoded protein is also able to release NEDD8, a ubiquiti1161159500161165723Human88description , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1315395USP32ubiquitin specific peptidase 32Enables cysteine-type deubiquitinase activity. Involved in positive regulation of TORC1 signaling. Located in cytosol. Is active in Golgi apparatus. [provided by Alliance of Genome Resources, Jul 2025]176017732760422416Human85old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1604943USP41Pubiquitin specific peptidase 41, pseudogeneINTERACTS WITH 3-isobutyl-1-methyl-7H-xanthine; 4,4'-sulfonyldiphenol; all-trans-retinoic acid222036361620377260Human12old_gene_symbolgene, pseudo, INFERRED [RefSeq]
1345113LINC00161long intergenic non-protein coding RNA 161INTERACTS WITH 17beta-hydroxy-5alpha-androstan-3-one; aflatoxin B1; benzo[a]pyrene212853931828540355Human7old_gene_symbolgene, ncrna, VALIDATED [RefSeq]
1317441USP30ubiquitin specific peptidase 30USP30, a member of the ubiquitin-specific protease family (see USP1, MIM 603478), is a novel mitochondrial deubiquitinating (DUB) enzyme (Nakamura and Hirose, 2008 [PubMed 18287522]).[supplied by OMIM, Dec 2008]12109023089109088023Human84descriptiongene, protein-coding, VALIDATED [RefSeq]
16566772AF129075.2novel transcript, antisense to USP16Humannamegene, lncrna
16560639AC130365.1ubiquitin specific peptidase 17 (USP17) pseudogene879673447968544Humannamegene, pseudo, INFERRED [RefSeq]
16561465AL512310.7ubiquitin specific peptidase 10 (USP10) pseudogeneHumannamegene, transcribed_processed_pseudogene
16552194AP000533.2ubiquitin specific peptidase 10 (USP10) pseudogeneHumannamegene, processed_pseudogene
16561219CR383656.1ubiquitin specific peptidase 10 (USP10) pseudogeneHumannamegene, processed_pseudogene
16560824AC087203.2ubiquitin specific peptidase 17-like 2 (USP17L2) pseudogeneHumannamegene, processed_pseudogene
16560232AC087203.1ubiquitin specific peptidase 17-like 2 ( USP17L2) pseudogene81237435412375546Humannamegene, pseudo, INFERRED [RefSeq]
1315150WDR20WD repeat domain 20This gene encodes a WD repeat-containing protein that functions to preserve and regulate the activity of the USP12-UAF1 deubiquitinating enzyme complex. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2014102139423102224839Human69descriptiongene, protein-coding, REVIEWED [RefSeq]