Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Genes search result for All species
(View Results for all Objects and Ontologies)

41 records found for search term Unc119
Refine Term:
Sort By:
           Export CSV TAB Print

RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
3942Unc119unc-119 lipid binding chaperoneENCODES a protein that exhibits lipid binding (ortholog); INVOLVED IN lipoprotein transport (ortholog); mitotic cytokinesis (ortholog); negative regulation of caveolin-mediated endocytosis (ortholog); ASSOCIATED WITH cone-rod dystrophy (ortholog); cone-rod dystrophy 24 (ortholog); idiopathic CD4-pos106373592763741404Rat130symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
1332505Unc119unc-119 lipid binding chaperoneThe protein encoded by this gene is multifunctional, affecting trafficking of transducin in rod photoreceptors, interacting with src-type tyrosine kinases through SH2 and SH3 interacting domains, and aiding the uptake of bacteria through endocytosis. In addition, the encoded protein acts as a lipid-117823432178239990Mouse132symbol , PhenoGen , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1343859UNC119unc-119 lipid binding chaperoneThis gene is specifically expressed in the photoreceptors in the retina. The encoded product shares strong homology with the C. elegans unc119 protein and it can functionally complement the C. elegans unc119 mutation. It has172854670728552628Human263symbol , COSMIC , description , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
8781154Unc119unc-119 lipid binding chaperoneENCODES a protein that exhibits lipid binding (ortholog); INVOLVED IN lipoprotein transport (ortholog); mitotic cytokinesis (ortholog); negative regulation of caveolin-mediated endocytosis (ortholog); ASSOCIATED WITH cone-rod dystrophy (ortholog); cone-rod dystrophy 24 (ortholog); idiopathic CD4-posNW_00495548145978394603313Chinchilla38symbolgene, protein-coding, MODEL [RefSeq]
11671916UNC119unc-119 lipid binding chaperoneENCODES a protein that exhibits lipid binding (ortholog); INVOLVED IN lipoprotein transport (ortholog); mitotic cytokinesis (ortholog); negative regulation of caveolin-mediated endocytosis (ortholog); ASSOCIATED WITH cone-rod dystrophy (ortholog); cone-rod dystrophy 24 (ortholog); idiopathic CD4-pos172822342828229361Bonobo38symbolgene, protein-coding, MODEL [RefSeq]
12422727UNC119unc-119 lipid binding chaperoneENCODES a protein that exhibits lipid binding (ortholog); INVOLVED IN lipoprotein transport (ortholog); mitotic cytokinesis (ortholog); negative regulation of caveolin-mediated endocytosis (ortholog); ASSOCIATED WITH cone-rod dystrophy (ortholog); cone-rod dystrophy 24 (ortholog); idiopathic CD4-pos94275457542760337Dog64symbolgene, protein-coding, MODEL [RefSeq]
12696910Unc119unc-119 lipid binding chaperoneENCODES a protein that exhibits lipid binding (inferred); INVOLVED IN positive regulation of protein tyrosine kinase activity (ortholog); ASSOCIATED WITH cone-rod dystrophy (ortholog); cone-rod dystrophy 24 (ortholog); idiopathic CD4-positive T-lymphocytopenia (ortholog); FOUND IN centrosome (inferrNW_00493653847722364778149Squirrel55symbolgene, protein-coding, MODEL [RefSeq]
14150054UNC119unc-119 lipid binding chaperoneENCODES a protein that exhibits lipid binding (inferred); INVOLVED IN positive regulation of protein tyrosine kinase activity (ortholog); ASSOCIATED WITH cone-rod dystrophy (ortholog); cone-rod dystrophy 24 (ortholog); idiopathic CD4-positive T-lymphocytopenia (ortholog); FOUND IN centrosome (inferrPig55symbolgene, protein-coding, MODEL [RefSeq]
18597294UNC119unc-119 lipid binding chaperoneENCODES a protein that exhibits lipid binding (inferred); INVOLVED IN positive regulation of protein tyrosine kinase activity (ortholog); ASSOCIATED WITH cone-rod dystrophy (ortholog); cone-rod dystrophy 24 (ortholog); idiopathic CD4-positive T-lymphocytopenia (ortholog); FOUND IN centrosome (inferrGreen Monkey54symbolgene, protein-coding, MODEL [RefSeq]
18924063Unc119unc-119 lipid binding chaperoneENCODES a protein that exhibits lipid binding (inferred); INVOLVED IN positive regulation of protein tyrosine kinase activity (ortholog); ASSOCIATED WITH cone-rod dystrophy (ortholog); cone-rod dystrophy 24 (ortholog); idiopathic CD4-positive T-lymphocytopenia (ortholog); FOUND IN centrosome (inferrNaked Mole-Rat46symbolgene, protein-coding, MODEL [RefSeq]
20866332UNC119unc-119 lipid binding chaperoneGreen Monkeysymbolgene, protein-coding
155248068unc119Tropical Clawed Frogsymbolgene, null
626073134Unc119unc-119 lipid binding chaperoneENCODES a protein that exhibits lipid binding (ortholog); INVOLVED IN lipoprotein transport (ortholog); mitotic cytokinesis (ortholog); negative regulation of caveolin-mediated endocytosis (ortholog); ASSOCIATED WITH cone-rod dystrophy (ortholog); cone-rod dystrophy 24 (ortholog); idiopathic CD4-posBlack Rat38symbolgene, protein-coding, MODEL [RefSeq]
155238314unc119.LAfrican Clawed Frogsymbolgene, null
1345863UNC119Bunc-119 lipid binding chaperone BEnables lipid binding activity. Involved in cilium assembly and lipoprotein transport. Located in ciliary transition zone. [provided by Alliance of Genome Resources, Jul 2025]12120710458120723640Human83symbol , old_gene_name , COSMIC , Human Proteome Mapgene, protein-coding, VALIDATED [RefSeq]
1602449MACIRmacrophage immunometabolism regulatorThis gene, MACIR (previously known as C5orf30), has been associated with rheumatoid arthritis, functioning as a negative regulator of tissue damage and modulating the activity of synovial fibroblasts and macrophages. The encoded protein is highly conserved in vertebrate genomes but has no significan5103258374103278660Human104old_gene_namegene, protein-coding, REVIEWED [RefSeq]
11997072MACIRmacrophage immunometabolism regulatorINVOLVED IN negative regulation of cytokine production involved in inflammatory response (ortholog); negative regulation of fibroblast migration (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Colonic Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN ciliary transition zone (inferred); ci59861289298632854Bonobo30old_gene_namegene, protein-coding, MODEL [RefSeq]
1562136Macirmacrophage immunometabolism regulatorINVOLVED IN negative regulation of cytokine production involved in inflammatory response (ortholog); negative regulation of fibroblast migration (ortholog); negative regulation of inflammatory response (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Colonic Neoplasms (ortholog); COVID-19 (o9105868072105888128Rat100old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
1621563Macirmacrophage immunometabolism regulatorActs upstream of or within negative regulation of cytokine production involved in inflammatory response; negative regulation of epithelial cell migration; and negative regulation of fibroblast migration. Predicted to be located in ciliary transition zone and cytoplasm. Is expressed in several struct19757162797589743Mouse117old_gene_namegene, protein-coding, VALIDATED [RefSeq]
8917108Macirmacrophage immunometabolism regulatorINVOLVED IN negative regulation of cytokine production involved in inflammatory response (ortholog); negative regulation of fibroblast migration (ortholog); negative regulation of inflammatory response (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Colonic Neoplasms (ortholog); COVID-19 (oNW_0049554181075225010767791Chinchilla23old_gene_namegene, protein-coding, MODEL [RefSeq]
12275012MACIRmacrophage immunometabolism regulatorINVOLVED IN negative regulation of cytokine production involved in inflammatory response (ortholog); negative regulation of fibroblast migration (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Colonic Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN ciliary transition zone (inferred); ci379568657968964Dog30old_gene_namegene, protein-coding, MODEL [RefSeq]
12563425Macirmacrophage immunometabolism regulatorINVOLVED IN negative regulation of cytokine production involved in inflammatory response (ortholog); negative regulation of fibroblast migration (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Colonic Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN ciliary transition zone (inferred); ciNW_00493652312738121292837Squirrel30old_gene_namegene, protein-coding, MODEL [RefSeq]
14148703MACIRmacrophage immunometabolism regulatorINVOLVED IN negative regulation of cytokine production involved in inflammatory response (ortholog); negative regulation of fibroblast migration (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Colonic Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN ciliary transition zone (inferred); ciPig30old_gene_namegene, protein-coding, MODEL [RefSeq]
18453918MACIRmacrophage immunometabolism regulatorINVOLVED IN negative regulation of cytokine production involved in inflammatory response (ortholog); negative regulation of fibroblast migration (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Colonic Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN ciliary transition zone (inferred); ciGreen Monkey30old_gene_namegene, protein-coding, MODEL [RefSeq]
18920850Macirmacrophage immunometabolism regulatorINVOLVED IN negative regulation of cytokine production involved in inflammatory response (ortholog); negative regulation of fibroblast migration (ortholog); negative regulation of inflammatory response (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Colonic Neoplasms (ortholog); COVID-19 (oNaked Mole-Rat28old_gene_namegene, protein-coding, MODEL [RefSeq]
626081883Macirmacrophage immunometabolism regulatorINVOLVED IN negative regulation of cytokine production involved in inflammatory response (ortholog); negative regulation of fibroblast migration (ortholog); negative regulation of inflammatory response (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Colonic Neoplasms (ortholog); COVID-19 (oBlack Rat22old_gene_namegene, protein-coding, MODEL [RefSeq]
1309359Unc119bunc-119 lipid binding chaperone BENCODES a protein that exhibits lipid binding (ortholog); INVOLVED IN cilium assembly (ortholog); lipoprotein transport (ortholog); FOUND IN ciliary transition zone (ortholog); sperm end piece (ortholog); sperm midpiece (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzo124713949247152115Rat83symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
1319666Unc119bunc-119 lipid binding chaperone BPredicted to enable lipid binding activity. Predicted to be involved in cilium assembly; lipoprotein transport; and nervous system development. Predicted to be located in ciliary transition zone. Predicted to be active in cilium. Is expressed in several structures, including central nervous system; 5115260625115273034Mouse90symbol , PhenoGen , descriptiongene, protein-coding, PROVISIONAL [RefSeq]
8929905Unc119bunc-119 lipid binding chaperone BENCODES a protein that exhibits lipid binding (ortholog); INVOLVED IN cilium assembly (ortholog); lipoprotein transport (ortholog); FOUND IN ciliary transition zone (ortholog); sperm end piece (ortholog); sperm midpiece (ortholog)NW_0049554551095012610963803Chinchilla11symbolgene, protein-coding, MODEL [RefSeq]
11980128UNC119Bunc-119 lipid binding chaperone BENCODES a protein that exhibits lipid binding (inferred); INVOLVED IN cell projection organization (inferred); cilium assembly (inferred); lipoprotein transport (inferred); FOUND IN ciliary transition zone (inferred); cilium (inferred); sperm end piece (inferred)12118293984118307156Bonobo20symbolgene, protein-coding, MODEL [RefSeq]
12153481UNC119Bunc-119 lipid binding chaperone BENCODES a protein that exhibits lipid binding (inferred); INVOLVED IN cell projection organization (inferred); cilium assembly (inferred); lipoprotein transport (inferred); FOUND IN ciliary transition zone (inferred); sperm end piece (inferred); sperm midpiece (inferred)261655772116569695Dog21symbolgene, protein-coding, MODEL [RefSeq]
12577451Unc119bunc-119 lipid binding chaperone BENCODES a protein that exhibits lipid binding (inferred); INVOLVED IN cell projection organization (inferred); cilium assembly (inferred); lipoprotein transport (inferred); FOUND IN ciliary transition zone (ortholog); sperm end piece (ortholog); sperm midpiece (ortholog)NW_004936668275573289938Squirrel17symbolgene, protein-coding, MODEL [RefSeq]
14200055UNC119Bunc-119 lipid binding chaperone BENCODES a protein that exhibits acyl-CoA dehydrogenase activity (inferred); flavin adenine dinucleotide binding (inferred); lipid binding (inferred); INVOLVED IN cell projection organization (inferred); cilium assembly (inferred); endocytosis (inferred); FOUND IN centrosome (inferred); ciliary transPig35symbolgene, protein-coding, MODEL [RefSeq]
18365652UNC119Bunc-119 lipid binding chaperone BENCODES a protein that exhibits lipid binding (inferred); INVOLVED IN cell projection organization (inferred); cilium assembly (inferred); lipoprotein transport (inferred); FOUND IN ciliary transition zone (inferred); cilium (inferred); sperm end piece (inferred)Green Monkey20symbolgene, protein-coding, MODEL [RefSeq]
18923201Unc119bunc-119 lipid binding chaperone BENCODES a protein that exhibits lipid binding (inferred); INVOLVED IN cell projection organization (inferred); cilium assembly (inferred); lipoprotein transport (inferred); FOUND IN ciliary transition zone (ortholog); sperm end piece (ortholog); sperm midpiece (ortholog)Naked Mole-Rat17symbolgene, protein-coding, MODEL [RefSeq]
155232528unc119bTropical Clawed Frogsymbolgene, null
625974203Unc119bunc-119 lipid binding chaperone BENCODES a protein that exhibits lipid binding (ortholog); INVOLVED IN cilium assembly (ortholog); lipoprotein transport (ortholog); FOUND IN ciliary transition zone (ortholog); sperm end piece (ortholog); sperm midpiece (ortholog)Black Rat11symbolgene, protein-coding, MODEL [RefSeq]
155250623unc119b.LAfrican Clawed Frogsymbolgene, null
155232527unc119b.SAfrican Clawed Frogsymbolgene, null
1307736MlecmalectinENCODES a protein that exhibits carbohydrate binding (ortholog); enzyme binding (ortholog); protein-folding chaperone binding (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol124711891847133598Rat127ensembl_gene_symbolgene, protein-coding, PROVISIONAL [RefSeq]
16561075AC069234.3novel transcript, antisense to UNC119BHumannamegene, lncrna