Unc119 (unc-119 lipid binding chaperone) - Rat Genome Database

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Gene: Unc119 (unc-119 lipid binding chaperone) Mus musculus
Analyze
Symbol: Unc119
Name: unc-119 lipid binding chaperone
RGD ID: 1332505
MGI Page MGI
Description: Predicted to enable lipid binding activity. Involved in lipoprotein transport; negative regulation of caveolin-mediated endocytosis; and negative regulation of clathrin-dependent endocytosis. Predicted to be located in cytoplasm. Predicted to be active in intercellular bridge and microtubule cytoskeleton. Is expressed in foregut; liver lobe; male reproductive gland or organ; metanephros; and retina layer. Human ortholog(s) of this gene implicated in cone-rod dystrophy 24 and immunodeficiency 13. Orthologous to human UNC119 (unc-119 lipid binding chaperone).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: D11Bhm52; HRG; HRG4; MRG; MRG4; protein unc-119 homolog A; retinal gene 4; retinal protein 4; Rg; Rg4; Rtg; Rtg4; UNC11; Unc119h
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391178,234,321 - 78,239,990 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1178,234,308 - 78,239,990 (+)EnsemblGRCm39 Ensembl
GRCm381178,343,495 - 78,349,164 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1178,343,482 - 78,349,164 (+)EnsemblGRCm38mm10GRCm38
MGSCv371178,157,024 - 78,162,658 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361178,159,717 - 78,165,351 (+)NCBIMGSCv36mm8
Celera1187,975,604 - 87,981,238 (+)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1146.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
centrosome  (IBA,ISO,ISS)
cytoplasm  (IEA)
intercellular bridge  (IBA,ISO,ISS)
spindle midzone  (IBA,ISO,ISS)
spindle pole  (IBA,ISO,ISS)

Molecular Function
lipid binding  (IBA,ISO,ISS)
protein binding  (IPI)

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:9321431   PMID:9761287   PMID:10349636   PMID:11006213   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11786539   PMID:11818371   PMID:12466851   PMID:12477932  
PMID:12819125   PMID:14757743   PMID:15226823   PMID:15489334   PMID:16141072   PMID:16141073   PMID:16565359   PMID:17174953   PMID:17579091   PMID:18296658   PMID:19592652   PMID:19781630  
PMID:20220094   PMID:21267068   PMID:21642972   PMID:21873635   PMID:24194600   PMID:24664735   PMID:27626380   PMID:29395339   PMID:31696965   PMID:32290105   PMID:32325033   PMID:36293380  
PMID:37175812   PMID:38355793  


Genomics

Comparative Map Data
Unc119
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391178,234,321 - 78,239,990 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1178,234,308 - 78,239,990 (+)EnsemblGRCm39 Ensembl
GRCm381178,343,495 - 78,349,164 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1178,343,482 - 78,349,164 (+)EnsemblGRCm38mm10GRCm38
MGSCv371178,157,024 - 78,162,658 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361178,159,717 - 78,165,351 (+)NCBIMGSCv36mm8
Celera1187,975,604 - 87,981,238 (+)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1146.74NCBI
UNC119
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381728,546,707 - 28,552,628 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1728,546,708 - 28,552,631 (-)EnsemblGRCh38hg38GRCh38
GRCh371726,873,725 - 26,879,646 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361723,897,852 - 23,903,770 (-)NCBINCBI36Build 36hg18NCBI36
Build 341723,897,852 - 23,903,770NCBI
Celera1723,732,750 - 23,738,671 (-)NCBICelera
Cytogenetic Map17q11.2NCBI
HuRef1723,082,548 - 23,088,469 (-)NCBIHuRef
CHM1_11726,935,427 - 26,941,348 (-)NCBICHM1_1
T2T-CHM13v2.01729,489,330 - 29,495,251 (-)NCBIT2T-CHM13v2.0
Unc119
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81063,735,927 - 63,741,404 (+)NCBIGRCr8
mRatBN7.21063,237,862 - 63,243,339 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1063,237,903 - 63,243,339 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1067,870,234 - 67,875,633 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01067,375,583 - 67,380,982 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01062,846,688 - 62,852,088 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01065,606,919 - 65,612,324 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1065,606,898 - 65,612,324 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01066,026,840 - 66,032,239 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41064,285,993 - 64,291,392 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11064,299,615 - 64,305,015 (-)NCBI
Celera1062,215,606 - 62,221,005 (+)NCBICelera
Cytogenetic Map10q25NCBI
Unc119
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554814,597,839 - 4,603,313 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554814,597,839 - 4,603,313 (+)NCBIChiLan1.0ChiLan1.0
UNC119
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21935,907,677 - 35,913,612 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11737,787,803 - 37,793,737 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01728,223,428 - 28,229,361 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11728,729,569 - 28,732,229 (+)NCBIpanpan1.1PanPan1.1panPan2
UNC119
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1942,754,575 - 42,760,337 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl942,754,887 - 42,760,482 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha941,911,236 - 41,917,005 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0943,573,537 - 43,579,307 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl943,573,540 - 43,579,444 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1942,356,587 - 42,362,351 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0942,649,035 - 42,654,797 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0942,726,501 - 42,732,272 (-)NCBIUU_Cfam_GSD_1.0
Unc119
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560241,894,288 - 41,900,215 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365384,772,283 - 4,778,137 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365384,772,236 - 4,778,149 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UNC119
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1244,801,267 - 44,807,339 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11244,801,265 - 44,807,334 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21246,785,656 - 46,791,681 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UNC119
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11622,315,900 - 22,321,806 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660757,804,980 - 7,810,919 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Unc119
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247861,134,162 - 1,141,474 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247861,134,508 - 1,140,831 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Unc119
89 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1516
Count of miRNA genes:531
Interacting mature miRNAs:643
Transcripts:ENSMUST00000002127, ENSMUST00000100755, ENSMUST00000108295, ENSMUST00000125720, ENSMUST00000149161, ENSMUST00000154700, ENSMUST00000155471
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
4141365Ltxs3_mlethal factor toxin susceptibility 3 (mouse)Not determined117757387380746358Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177770978111771099Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177437183111437322Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172726125106726289Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172818615106818733Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177437183111437322Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172818615106818733Mouse
1301078Alcp2_malcohol preference locus 2 (mouse)Not determined117220979684731462Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177063779111063918Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116707819179813912Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116331940781830473Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
12903994Opfaq3_mopen field activity QTL 3 (mouse)117373754182069425Mouse
1302124Eae7_msusceptibility to experimental allergic encephalomyelitis 7 (mouse)Not determined117757387399377820Mouse

Markers in Region
RH129323  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381178,342,501 - 78,342,728UniSTSGRCm38
MGSCv371178,156,003 - 78,156,230UniSTSGRCm37
Celera1187,974,583 - 87,974,810UniSTS
Cytogenetic Map11B5UniSTS
cM Map1144.99UniSTS
UniSTS:236658  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381178,341,819 - 78,342,098UniSTSGRCm38
MGSCv371178,155,321 - 78,155,600UniSTSGRCm37
Celera1187,973,901 - 87,974,180UniSTS
Cytogenetic Map11B5UniSTS
cM Map1144.99UniSTS
D11Seg21  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381178,344,963 - 78,345,095UniSTSGRCm38
MGSCv371178,158,465 - 78,158,597UniSTSGRCm37
Celera1187,977,045 - 87,977,177UniSTS
Cytogenetic Map11B5UniSTS
cM Map1145.01UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000002127   ⟹   ENSMUSP00000002127
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1178,234,308 - 78,239,990 (+)Ensembl
GRCm38.p6 Ensembl1178,343,482 - 78,349,164 (+)Ensembl
Ensembl Acc Id: ENSMUST00000100755   ⟹   ENSMUSP00000098318
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1178,237,492 - 78,239,805 (+)Ensembl
GRCm38.p6 Ensembl1178,346,666 - 78,348,979 (+)Ensembl
Ensembl Acc Id: ENSMUST00000108295   ⟹   ENSMUSP00000103930
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1178,234,332 - 78,239,990 (+)Ensembl
GRCm38.p6 Ensembl1178,343,506 - 78,349,164 (+)Ensembl
Ensembl Acc Id: ENSMUST00000125720
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1178,238,761 - 78,239,824 (+)Ensembl
GRCm38.p6 Ensembl1178,347,935 - 78,348,998 (+)Ensembl
Ensembl Acc Id: ENSMUST00000149161
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1178,234,371 - 78,239,722 (+)Ensembl
GRCm38.p6 Ensembl1178,343,545 - 78,348,896 (+)Ensembl
Ensembl Acc Id: ENSMUST00000154700
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1178,234,324 - 78,238,675 (+)Ensembl
GRCm38.p6 Ensembl1178,343,498 - 78,347,849 (+)Ensembl
Ensembl Acc Id: ENSMUST00000155471
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1178,237,737 - 78,238,945 (+)Ensembl
GRCm38.p6 Ensembl1178,346,911 - 78,348,119 (+)Ensembl
RefSeq Acc Id: NM_001313985   ⟹   NP_001300914
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391178,234,321 - 78,239,990 (+)NCBI
GRCm381178,343,495 - 78,349,164 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001313986   ⟹   NP_001300915
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391178,237,536 - 78,239,990 (+)NCBI
GRCm381178,346,710 - 78,349,164 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001313987   ⟹   NP_001300916
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391178,237,536 - 78,239,990 (+)NCBI
GRCm381178,346,710 - 78,349,164 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001313988   ⟹   NP_001300917
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391178,236,410 - 78,239,990 (+)NCBI
GRCm381178,345,584 - 78,349,164 (+)NCBI
Sequence:
RefSeq Acc Id: NM_011676   ⟹   NP_035806
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391178,234,321 - 78,239,990 (+)NCBI
GRCm381178,343,495 - 78,349,164 (+)NCBI
MGSCv371178,157,024 - 78,162,658 (+)RGD
Celera1187,975,604 - 87,981,238 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_035806   ⟸   NM_011676
- Peptide Label: isoform 2
- UniProtKB: Q9Z2R6 (UniProtKB/Swiss-Prot),   Q3V299 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001300914   ⟸   NM_001313985
- Peptide Label: isoform 1
- UniProtKB: B1AQD9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001300917   ⟸   NM_001313988
- Peptide Label: isoform 5
- UniProtKB: Q3V299 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001300915   ⟸   NM_001313986
- Peptide Label: isoform 3
- Sequence:
RefSeq Acc Id: NP_001300916   ⟸   NM_001313987
- Peptide Label: isoform 4
- UniProtKB: B1AQD7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000103930   ⟸   ENSMUST00000108295
Ensembl Acc Id: ENSMUSP00000002127   ⟸   ENSMUST00000002127
Ensembl Acc Id: ENSMUSP00000098318   ⟸   ENSMUST00000100755
Protein Domains
GMP phosphodiesterase delta subunit

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z2R6-F1-model_v2 AlphaFold Q9Z2R6 1-240 view protein structure

Promoters
RGD ID:6822421
Promoter ID:MM_KWN:8706
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Kidney,   Liver,   Lung,   Spleen
Transcripts:ENSMUST00000108295,   OTTMUST00000000432,   OTTMUST00000000435,   OTTMUST00000000436
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361178,156,879 - 78,157,379 (+)MPROMDB
RGD ID:6822422
Promoter ID:MM_KWN:8707
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour
Transcripts:OTTMUST00000000433,   OTTMUST00000000434
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361178,158,926 - 78,159,426 (+)MPROMDB
RGD ID:8675714
Promoter ID:EPDNEW_M15888
Type:initiation region
Name:Unc119_1
Description:Mus musculus unc-119 lipid binding chaperone , transcript variant4, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381178,343,494 - 78,343,554EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1328357 AgrOrtholog
Ensembl Genes ENSMUSG00000002058 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000002127 ENTREZGENE
  ENSMUST00000002127.14 UniProtKB/Swiss-Prot
  ENSMUST00000100755 ENTREZGENE
  ENSMUST00000100755.4 UniProtKB/TrEMBL
  ENSMUST00000108295 ENTREZGENE
  ENSMUST00000108295.8 UniProtKB/TrEMBL
Gene3D-CATH 2.70.50.40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ig_E-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDE6D_unc-119_myristoyl-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDED_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDED_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:22248 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1328357 ENTREZGENE
NCBI Gene 22248 ENTREZGENE
PANTHER PTHR12951:SF5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RETINAL PROTEIN 4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam GMP_PDE_delta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Unc119 PhenoGen
Superfamily-SCOP SSF81296 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B1AQD7 ENTREZGENE, UniProtKB/TrEMBL
  B1AQD9 ENTREZGENE, UniProtKB/TrEMBL
  Q3V299 ENTREZGENE, UniProtKB/TrEMBL
  Q9Z2R6 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-05 Unc119  unc-119 lipid binding chaperone  Rtg4  retinal gene 4  Data merged from RGD:1610936 737654 PROVISIONAL
2016-03-14 Unc119  unc-119 lipid binding chaperone    unc-119 homolog (C. elegans)  Symbol and/or name change 5135510 APPROVED