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17 records found for search term Srebf2
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
730972SREBF2sterol regulatory element binding transcription factor 2This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 224183310541907305Human425symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
730973Srebf2sterol regulatory element binding factor 2Enables DNA-binding transcription factor activity, RNA polymerase II-specific and transcription cis-regulatory region binding activity. Involved in positive regulation of cholesterol biosynthetic process; positive regulation of miRNA transcription; and positive regulation of myelination. Acts upstre158203145582089580Mouse433symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
1307751Srebf2sterol regulatory element binding transcription factor 2ENCODES a protein that exhibits chromatin binding; sequence-specific DNA binding; C-8 sterol isomerase activity (ortholog); INVOLVED IN positive regulation of DNA-templated transcription; positive regulation of transcription by RNA polymerase II; response to hormone; PARTICIPATES IN altered p53 sign7115542774115600945Rat430symbol , PhenoGen , old_gene_symbolgene, protein-coding, PROVISIONAL [RefSeq]
9061920Srebf2sterol regulatory element binding transcription factor 2ENCODES a protein that exhibits C-8 sterol isomerase activity (ortholog); chromatin binding (ortholog); DNA binding (ortholog); INVOLVED IN cellular response to low-density lipoprotein particle stimulus (ortholog); cellular response to starvation (ortholog); cholesterol homeostasis (ortholog); PARTINW_0049554132727171727326655Chinchilla94symbolgene, protein-coding, MODEL [RefSeq]
11942423SREBF2sterol regulatory element binding transcription factor 2ENCODES a protein that exhibits C-8 sterol isomerase activity (ortholog); chromatin binding (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN cholesterol homeostasis (ortholog); negative regulation of cholesterol efflux (ortholog); positive regulation of cholesterol storage (ortholog222272579022799749Bonobo103symbolgene, protein-coding, MODEL [RefSeq]
12245430SREBF2sterol regulatory element binding transcription factor 2ENCODES a protein that exhibits C-8 sterol isomerase activity (ortholog); INVOLVED IN negative regulation of cholesterol efflux (ortholog); positive regulation of cholesterol storage (ortholog); positive regulation of protein targeting to mitochondrion (ortholog); PARTICIPATES IN altered p53 signali102345192323532765Dog74symbolgene, protein-coding, MODEL [RefSeq]
12522113Srebf2sterol regulatory element binding transcription factor 2ENCODES a protein that exhibits C-8 sterol isomerase activity (ortholog); chromatin binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN cellular response to low-density lipoprotein particle stimulus (ortholog); cellular response to starvation (ortholog); cholesterolNW_004936492115923174614Squirrel103symbolgene, protein-coding, MODEL [RefSeq]
626077102Srebf2sterol regulatory element binding transcription factor 2ENCODES a protein that exhibits C-8 sterol isomerase activity (ortholog); chromatin binding (ortholog); DNA binding (ortholog); INVOLVED IN cellular response to low-density lipoprotein particle stimulus (ortholog); cellular response to starvation (ortholog); cholesterol homeostasis (ortholog); PARTIBlack Rat94symbolgene, protein-coding, MODEL [RefSeq]
18909174Srebf2sterol regulatory element binding transcription factor 2ENCODES a protein that exhibits C-8 sterol isomerase activity (ortholog); chromatin binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN cellular response to low-density lipoprotein particle stimulus (ortholog); cellular response to starvation (ortholog); cholesterolNaked Mole-Rat103symbolgene, protein-coding, MODEL [RefSeq]
14245787SREBF2sterol regulatory element binding transcription factor 2ENCODES a protein that exhibits C-8 sterol isomerase activity (ortholog); chromatin binding (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN cholesterol homeostasis (ortholog); negative regulation of cholesterol efflux (ortholog); positive regulation of cholesterol storage (orthologPig102symbolgene, protein-coding, MODEL [RefSeq]
155238294srebf2Tropical Clawed Frogsymbolgene, null
18786274SREBF2sterol regulatory element binding transcription factor 2ENCODES a protein that exhibits C-8 sterol isomerase activity (ortholog); chromatin binding (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN cholesterol homeostasis (ortholog); negative regulation of cholesterol efflux (ortholog); positive regulation of cholesterol storage (orthologGreen Monkey103symbolgene, protein-coding, MODEL [RefSeq]
155240653srebf2.LAfrican Clawed Frogsymbolgene, null
155238293srebf2.SAfrican Clawed Frogsymbolgene, null
14909010SREBF2-AS1SREBF2 antisense RNA 1224182748141834665Humansymbol , COSMIC , name , Human Proteome Mapgene, ncrna, VALIDATED [RefSeq]
728900Srebf2_v1sterol regulatory element binding factor 2, variant 1ENCODES an splice that exhibits DNA-binding transcription factor activity (inferred); INVOLVED IN spermatogenesisRat2symbolgene, splice
728894Srebf2_v2sterol regulatory element binding factor 2, variant 2INVOLVED IN positive regulation of DNA-templated transcriptionRat1symbolgene, splice