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Gene: SREBF2 (sterol regulatory element binding transcription factor 2) Canis lupus familiaris
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Symbol: SREBF2
Name: sterol regulatory element binding transcription factor 2
RGD ID: 12245430
Description: ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN aging (ortholog); positive regulation of cholesterol biosynthetic process (ortholog); positive regulation of protein targeting to mitochondrion (ortholog); PARTICIPATES IN altered p53 signaling pathway; sterol regulatory element-binding protein signaling pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); carotid artery disease (ortholog); cholelithiasis (ortholog); FOUND IN cytoplasm (ortholog); dendrite (ortholog); endoplasmic reticulum (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: CCDC134; coiled-coil domain containing 134; coiled-coil domain-containing protein 134; SREBP2; sterol regulatory element-binding protein 2
Orthologs:
Homo sapiens (human) : SREBF2 (sterol regulatory element binding transcription factor 2)  HGNC  Alliance
Mus musculus (house mouse) : Srebf2 (sterol regulatory element binding factor 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Srebf2 (sterol regulatory element binding transcription factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Srebf2 (sterol regulatory element binding transcription factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SREBF2 (sterol regulatory element binding transcription factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Srebf2 (sterol regulatory element binding transcription factor 2)
Sus scrofa (pig) : SREBF2 (sterol regulatory element binding transcription factor 2)
Chlorocebus sabaeus (African green monkey) : SREBF2 (sterol regulatory element binding transcription factor 2)
Heterocephalus glaber (naked mole-rat) : Srebf2 (sterol regulatory element binding transcription factor 2)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1023,452,561 - 23,518,689 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1023,518,672 - 23,532,676 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11023,451,923 - 23,532,765 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
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Nomenclature History
  
More on SREBF2
NCBI Gene
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RGD Object Information
RGD ID: 12245430
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-09-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.