| 620220 | Sh3bp5 | SH3-domain binding protein 5 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); protein kinase inhibitor activity (ortholog); INVOLVED IN intracellular signal transduction (ortholog); negative regulation of protein kinase activity (ortholog); FOUND IN mitochondrion; cytoplasmic vesicle membra ne (ortholog); nuclear body (ortholog); INTERACTS WITH (+)-schisandrin B; 1,3,5-trinitro-1,3,5-triazinane; 17alpha-ethynylestradiol | 16 | 6589877 | 6676524 | Rat | 174 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 733305 | SH3BP5 | SH3 domain binding protein 5 | Enables guanyl-nucleotide exchange factor activity and protein kinase inhibitor activity. Acts upstream of or within intracellular signal transduction. Located in cytoplasmic vesicle membrane and nuclear body. [provided by Alliance of Genome Resources, Jul 2025] | 3 | 15254353 | 15341380 | Human | 167 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1552598 | Sh3bp5 | SH3-domain binding protein 5 (BTK-associated) | Predicted to enable guanyl-nucleotide exchange factor activity and protein kinase inhibitor activity. Involved in negative regulation of protein kinase activity. Predicted to be located in cytoplasmic vesicle membrane; mitochondrion; and nuclear body. Predicted to be active in cytoplasm. Is expresse d in cerebral cortex ventricular layer and cortical plate. Orthologous to human SH3BP5 (SH3 domain binding protein 5). [provided by Alliance of Genome Resources, Jul 2025] | 14 | 31094571 | 31158056 | Mouse | 172 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8759121 | Sh3bp5 | SH3 domain binding protein 5 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); protein kinase inhibitor activity (ortholog); INVOLVED IN intracellular signal transduction (ortholog); negative regulation of protein kinase activity (ortholog); FOUND IN cytoplasmic vesicle membrane (ortholog); mitochondrion (ortholog); nuclear body (ortholog) | NW_004955430 | 2251544 | 2266166 | Chinchilla | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11777586 | SH3BP5 | SH3 domain binding protein 5 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); protein kinase inhibitor activity (inferred); SH3 domain binding (inferred); INVOLVED IN intracellular signal transduction (ortholog); negative regulation of protein kinase activity (ortholog); FOUND IN mitochondr ion (ortholog) | 3 | 15180369 | 15257951 | Bonobo | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12309502 | SH3BP5 | SH3 domain binding protein 5 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); protein kinase inhibitor activity (inferred); SH3 domain binding (inferred); INVOLVED IN intracellular signal transduction (ortholog); negative regulation of protein kinase activity (ortholog); FOUND IN mitochondr ion (ortholog) | 23 | 27258502 | 27335175 | Dog | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12647330 | Sh3bp5 | SH3 domain binding protein 5 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); protein kinase inhibitor activity (inferred); SH3 domain binding (inferred); INVOLVED IN intracellular signal transduction (ortholog); negative regulation of protein kinase activity (ortholog); FOUND IN mitochondr ion (ortholog) | NW_004936473 | 3103878 | 3110435 | Squirrel | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14251091 | SH3BP5 | SH3 domain binding protein 5 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); protein kinase inhibitor activity (inferred); SH3 domain binding (inferred); INVOLVED IN intracellular signal transduction (ortholog); negative regulation of protein kinase activity (ortholog); FOUND IN mitochondr ion (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18508301 | SH3BP5 | SH3 domain binding protein 5 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); protein kinase inhibitor activity (inferred); SH3 domain binding (inferred); INVOLVED IN intracellular signal transduction (ortholog); negative regulation of protein kinase activity (ortholog); FOUND IN mitochondr ion (ortholog) | | | | Green Monkey | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18934420 | Sh3bp5 | SH3 domain binding protein 5 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); protein kinase inhibitor activity (inferred); SH3 domain binding (inferred); INVOLVED IN intracellular signal transduction (ortholog); negative regulation of protein kinase activity (ortholog); FOUND IN cytoplasmi c vesicle membrane (ortholog); mitochondrion (ortholog); nuclear body (ortholog) | | | | Naked Mole-Rat | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155255219 | sh3bp5 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626122389 | Sh3bp5 | SH3 domain binding protein 5 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); protein kinase inhibitor activity (ortholog); INVOLVED IN intracellular signal transduction (ortholog); negative regulation of protein kinase activity (ortholog); FOUND IN cytoplasmic vesicle membrane (ortholog); mitochondrion (ortholog); nuclear body (ortholog) | | | | Black Rat | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155251901 | sh3bp5.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155258517 | sh3bp5.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 7174998 | SH3BP5-AS1 | SH3BP5 antisense RNA 1 | INTERACTS WITH acrylamide; fipronil; leflunomide | 3 | 15254184 | 15264498 | Human | 6 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 12300851 | METTL6 | methyltransferase 6, tRNA N3-cytidine | ENCODES a protein that exhibits enzyme binding (ortholog); INVOLVED IN tRNA C3-cytosine methylation (ortholog); tRNA modification (ortholog); PARTICIPATES IN selenoamino acid metabolic pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); FOUND IN tRNA methyltransferase complex (ortholog) | 23 | 27202880 | 27217753 | Dog | 19 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 1553860 | Sh3bp5l | SH3 binding domain protein 5 like | Predicted to enable guanyl-nucleotide exchange factor activity and protein kinase inhibitor activity. Predicted to be involved in intracellular signal transduction. Predicted to be active in cytoplasm. Is expressed in cerebral cortex subventricular zone and cortical plate. Orthologous to human SH3BP5 style='font-weight:700;'>SH3BP5L (SH3 binding domain protein 5 like). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 58221533 | 58238554 | Mouse | 65 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1590939 | Sh3bp5l | SH3 binding domain protein 5 like | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN intracellular signal transduction (inferred); FOUND IN cytoplasm (inferred); INTERACTS WITH 4,4'-sulfonyldiphenol; bisphenol A; bisphenol F | 10 | 43012902 | 43027319 | Rat | 58 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1606500 | SH3BP5L | SH3 binding domain protein 5 like | Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in intracellular signal transduction. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025] | 1 | 248810446 | 248825915 | Human | 68 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 8747775 | Sh3bp5l | SH3 binding domain protein 5 like | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog) | NW_004955418 | 29884660 | 29893611 | Chinchilla | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11899497 | SH3BP5L | SH3 binding domain protein 5 like | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); protein kinase inhibitor activity (inferred); SH3 domain binding (inferred); INVOLVED IN intracellular signal transduction (inferred); FOUND IN cytoplasm (inferred) | 1 | 224453925 | 224470497 | Bonobo | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12054999 | SH3BP5L | SH3 binding domain protein 5 like | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); SH3 domain binding (inferred); INVOLVED IN intracellular signal transduction (inferred); FOUND IN cytoplasm (inferred) | 16 | 13709586 | 13723908 | Dog | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12726725 | Sh3bp5l | SH3 binding domain protein 5 like | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); protein kinase inhibitor activity (inferred); SH3 domain binding (inferred); INVOLVED IN intracellular signal transduction (inferred); FOUND IN cytoplasm (inferred) | NW_004936609 | 571600 | 584572 | Squirrel | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14212314 | SH3BP5L | SH3 binding domain protein 5 like | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); SH3 domain binding (inferred); INVOLVED IN intracellular signal transduction (inferred); FOUND IN cytoplasm (inferred) | | | | Pig | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18777269 | SH3BP5L | SH3 binding domain protein 5 like | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); protein kinase inhibitor activity (inferred); SH3 domain binding (inferred); INVOLVED IN intracellular signal transduction (inferred); FOUND IN cytoplasm (inferred) | | | | Green Monkey | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18918665 | Sh3bp5l | SH3 binding domain protein 5 like | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); protein kinase inhibitor activity (inferred); SH3 domain binding (inferred); INVOLVED IN intracellular signal transduction (inferred); FOUND IN cytoplasm (inferred) | | | | Naked Mole-Rat | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155234336 | sh3bp5l | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625945928 | Sh3bp5l | SH3 binding domain protein 5 like | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog) | | | | Black Rat | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155234337 | sh3bp5l.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155235457 | sh3bp5l.S | | | | | | African Clawed Frog | | symbol | gene, null |