Sh3bp5 (SH3 domain binding protein 5) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Sh3bp5 (SH3 domain binding protein 5) Heterocephalus glaber
Analyze
Symbol: Sh3bp5
Name: SH3 domain binding protein 5
RGD ID: 18934420
Description: ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); protein kinase inhibitor activity (inferred); SH3 domain binding (inferred); INVOLVED IN intracellular signal transduction (ortholog); ASSOCIATED WITH 3p deletion syndrome (ortholog); genetic disease (ortholog); FOUND IN cytoplasmic vesicle membrane (ortholog); mitochondrion (ortholog); nuclear body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SH3 domain-binding protein 5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248224,950,735 - 5,021,337 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248224,950,735 - 5,021,233 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Sh3bp5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248224,950,735 - 5,021,337 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248224,950,735 - 5,021,233 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SH3BP5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38315,254,353 - 15,341,380 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl315,254,353 - 15,341,368 (-)EnsemblGRCh38hg38GRCh38
GRCh37315,295,860 - 15,382,887 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36315,271,361 - 15,357,905 (-)NCBINCBI36Build 36hg18NCBI36
Build 34315,271,367 - 15,348,892NCBI
Celera315,234,616 - 15,321,139 (-)NCBICelera
Cytogenetic Map3p25.1NCBI
HuRef315,231,318 - 15,318,336 (-)NCBIHuRef
CHM1_1315,246,746 - 15,333,790 (-)NCBICHM1_1
T2T-CHM13v2.0315,256,759 - 15,343,784 (-)NCBIT2T-CHM13v2.0
Sh3bp5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391431,094,571 - 31,158,056 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1431,081,837 - 31,158,035 (-)EnsemblGRCm39 Ensembl
GRCm381431,372,614 - 31,436,100 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1431,359,880 - 31,436,078 (-)EnsemblGRCm38mm10GRCm38
MGSCv371432,187,141 - 32,249,219 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361430,203,993 - 30,264,870 (-)NCBIMGSCv36mm8
Celera1427,632,639 - 27,694,829 (-)NCBICelera
Cytogenetic Map14BNCBI
cM Map1419.11NCBI
Sh3bp5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8166,589,877 - 6,676,524 (-)NCBIGRCr8
mRatBN7.2166,583,462 - 6,678,344 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl166,583,465 - 6,698,975 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx166,595,768 - 6,660,252 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0167,740,664 - 7,805,146 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0166,602,675 - 6,667,565 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0167,473,367 - 7,559,976 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl167,473,370 - 7,538,201 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0167,408,996 - 7,472,907 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4166,822,512 - 6,888,922 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1166,822,512 - 6,888,920 (-)NCBI
Celera168,541,799 - 8,606,037 (+)NCBICelera
Cytogenetic Map16p16NCBI
Sh3bp5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554302,196,967 - 2,264,953 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554302,251,544 - 2,266,166 (+)NCBIChiLan1.0ChiLan1.0
SH3BP5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2215,239,521 - 15,317,375 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1315,244,282 - 15,321,989 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0315,180,369 - 15,257,951 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1315,517,447 - 15,594,971 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl315,517,447 - 15,594,971 (-)Ensemblpanpan1.1panPan2
SH3BP5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12327,258,502 - 27,335,175 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2327,202,875 - 27,334,010 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2327,232,632 - 27,309,150 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02327,770,472 - 27,847,079 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2327,715,728 - 27,847,075 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12327,460,017 - 27,536,480 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02327,521,691 - 27,598,215 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02327,770,953 - 27,847,541 (+)NCBIUU_Cfam_GSD_1.0
Sh3bp5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118169,965,168 - 169,971,857 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364733,038,963 - 3,109,174 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364733,103,878 - 3,110,435 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SH3BP5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl132,506,156 - 2,585,526 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1132,504,282 - 2,585,601 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2132,433,078 - 2,512,617 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SH3BP5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11560,098,901 - 60,175,421 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1560,100,132 - 60,175,349 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604133,128,495 - 33,204,981 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000003966   ⟹   ENSHGLP00000003908
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248224,950,735 - 5,021,337 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000003967   ⟹   ENSHGLP00000003909
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248224,951,984 - 4,995,019 (-)Ensembl
RefSeq Acc Id: XM_004864401   ⟹   XP_004864458
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248224,950,735 - 5,021,233 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004864458 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000003908
GenBank Protein JAO03156 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004864458   ⟸   XM_004864401
- UniProtKB: A0A0P6K8K9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000003909   ⟸   ENSHGLT00000003967
RefSeq Acc Id: ENSHGLP00000003908   ⟸   ENSHGLT00000003966


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000002882 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000003966 ENTREZGENE
InterPro SH3BP5 UniProtKB/TrEMBL
NCBI Gene Sh3bp5 ENTREZGENE
PANTHER PTHR19423 UniProtKB/TrEMBL
  SH3 DOMAIN-BINDING PROTEIN 5 UniProtKB/TrEMBL
Pfam SH3BP5 UniProtKB/TrEMBL
UniProt A0A0P6K8K9 ENTREZGENE, UniProtKB/TrEMBL