| 69357 | Rrad | RRAD, Ras related glycolysis inhibitor and calcium channel regulator | ENCODES a protein that exhibits calmodulin binding (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN negative regulation of cell growth; ASSOCIATED WITH Breast Neoplasms (ortholog); Cardiac Arrhythmias (ortholog); Cardiomegaly (ortholog); FOUND IN plasma membrane (ortholog) ; T-tubule (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 19 | 360581 | 363874 | Rat | 217 | symbol , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 736416 | RRAD | RRAD, Ras related glycolysis inhibitor and calcium channel regulator | Predicted to enable GTP binding activity and calcium channel regulator activity. Predicted to be involved in small GTPase-mediated signal transduction. Predicted to be located in T-tubule. Predicted to be active in plasma membrane. Implicated in type 2 diabetes mellitus. Biomarker of congestive hear t failure. [provided by Alliance of Genome Resources, Jul 2025] | 16 | 66921685 | 66925535 | Human | 218 | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 736417 | Rrad | Ras-related associated with diabetes | Predicted to enable GTP binding activity and calcium channel regulator activity. Predicted to be involved in negative regulation of cell growth. Located in T-tubule. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gla nd; and musculature. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human RRAD (RRAD, Ras related glycolysis inhibitor and calcium channel regulator). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 105354702 | 105357921 | Mouse | 221 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8871419 | Rrad | RRAD, Ras related glycolysis inhibitor and calcium channel regulator | INVOLVED IN negative regulation of cell growth (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Cardiac Arrhythmias (ortholog); Cardiomegaly (ortholog); FOUND IN plasma membrane (ortholog); T-tubule (ortholog) | NW_004955433 | 23426258 | 23439094 | Chinchilla | 15 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 11943517 | RRAD | RRAD, Ras related glycolysis inhibitor and calcium channel regulator | INVOLVED IN negative regulation of cell growth (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Cardiac Arrhythmias (ortholog); Cardiomegaly (ortholog); FOUND IN plasma membrane (ortholog); T-tubule (ortholog) | 16 | 47236886 | 47240799 | Bonobo | 15 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 12408234 | RRAD | RRAD, Ras related glycolysis inhibitor and calcium channel regulator | ENCODES a protein that exhibits calmodulin binding (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN negative regulation of cell growth (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Cardiac Arrhythmias (ortholog); Cardiomegaly (ortholog); FOUND IN plasma membrane (ortholog); T-tubule (ortholog); INTERACTS WITH bisphenol A | 5 | 82392608 | 82395574 | Dog | 27 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 12636388 | Rrad | RRAD, Ras related glycolysis inhibitor and calcium channel regulator | ENCODES a protein that exhibits calcium channel regulator activity (inferred); calmodulin binding (inferred); GTP binding (inferred); INVOLVED IN negative regulation of cell growth (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Cardiac Arrhythmias (ortholog); Cardiomegaly (ortholog); FOUND IN T-tubule (ortholog) | NW_004936475 | 17173170 | 17176446 | Squirrel | 25 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 13863016 | RRAD | RRAD, Ras related glycolysis inhibitor and calcium channel regulator | ENCODES a protein that exhibits calmodulin binding (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN negative regulation of cell growth (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Cardiac Arrhythmias (ortholog); Cardiomegaly (ortholog); FOUND IN plasma membrane (ortholog); T-tubule (ortholog) | | | | Pig | 26 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 18554592 | RRAD | RRAD, Ras related glycolysis inhibitor and calcium channel regulator | ENCODES a protein that exhibits calcium channel regulator activity (inferred); calmodulin binding (inferred); GTP binding (inferred); INVOLVED IN negative regulation of cell growth (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Cardiac Arrhythmias (ortholog); Cardiomegaly (ortholog); FOUND IN T-tubule (ortholog) | | | | Green Monkey | 25 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 18906250 | Rrad | RRAD, Ras related glycolysis inhibitor and calcium channel regulator | ENCODES a protein that exhibits calcium channel regulator activity (inferred); calmodulin binding (inferred); GTP binding (inferred); INVOLVED IN negative regulation of cell growth (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Cardiac Arrhythmias (ortholog); Cardiomegaly (ortholog); FOUND IN T-tubule (ortholog) | | | | Naked Mole-Rat | 25 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 155240802 | rrad | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626041856 | Rrad | RRAD, Ras related glycolysis inhibitor and calcium channel regulator | INVOLVED IN negative regulation of cell growth (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Cardiac Arrhythmias (ortholog); Cardiomegaly (ortholog); FOUND IN plasma membrane (ortholog); T-tubule (ortholog) | | | | Black Rat | 15 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 155255601 | rrad.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155248344 | rrad.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1306560 | Rem1 | RRAD and GEM like GTPase 1 | ENCODES a protein that exhibits transmembrane transporter binding (ortholog); INVOLVED IN negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel (ortholog); regulation of skeletal muscle contraction by calcium ion signaling (ortholog); ASSOCIATED WITH long QT syndrome (ortholog); FOUND IN I band (ortholog); T-tubule (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide | 3 | 161563984 | 161572478 | Rat | 52 | name | gene, protein-coding, VALIDATED [RefSeq] |
| 1315248 | REM1 | RRAD and GEM like GTPase 1 | The protein encoded by this gene is a GTPase and member of the RAS-like GTP-binding protein family. The encoded protein is expressed in endothelial cells, where it promotes reorganization of the actin cytoskeleton and morphological changes in the cells. [provided by RefSeq, Jul 2008] | 20 | 31475288 | 31484895 | Human | 50 | name | gene, protein-coding, REVIEWED [RefSeq] |
| 8784605 | Rem1 | RRAD and GEM like GTPase 1 | ENCODES a protein that exhibits transmembrane transporter binding (ortholog); INVOLVED IN negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel (ortholog); regulation of skeletal muscle contraction by calcium ion signaling (ortholog); ASSOCIATED WITH long QT syndrome (ortholog); FOUND IN I band (ortholog); T-tubule (ortholog) | NW_004955422 | 29434477 | 29443172 | Chinchilla | 7 | name | gene, protein-coding, MODEL [RefSeq] |
| 11787075 | REM1 | RRAD and GEM like GTPase 1 | ENCODES a protein that exhibits calcium channel regulator activity (inferred); calmodulin binding (inferred); GTP binding (inferred); INVOLVED IN negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel (ortholog); regulation of skeletal muscle contraction by calcium ion signaling (ortholog); ASSOCIATED WITH long QT syndrome (ortholog); FOUND IN I band (inferred); plasma membrane (inferred); T-tubule (inferred) | 20 | 27764390 | 27774026 | Bonobo | 18 | name | gene, protein-coding, MODEL [RefSeq] |
| 12367339 | REM1 | RRAD and GEM like GTPase 1 | ENCODES a protein that exhibits calmodulin binding (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel (ortholog); regulation of skeletal muscle contraction by calcium ion signal ing (ortholog); ASSOCIATED WITH long QT syndrome (ortholog); FOUND IN I band (inferred); T-tubule (inferred) | 24 | 20991166 | 21000019 | Dog | 18 | name | gene, protein-coding, MODEL [RefSeq] |
| 12591240 | Rem1 | RRAD and GEM like GTPase 1 | ENCODES a protein that exhibits calcium channel regulator activity (inferred); calmodulin binding (inferred); GTP binding (inferred); INVOLVED IN negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel (ortholog); regulation of skeletal muscle contraction by calcium ion signaling (ortholog); ASSOCIATED WITH long QT syndrome (ortholog); FOUND IN I band (inferred); plasma membrane (inferred); T-tubule (inferred) | NW_004936485 | 18504086 | 18512761 | Squirrel | 18 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 13893524 | REM1 | RRAD and GEM like GTPase 1 | ENCODES a protein that exhibits calmodulin binding (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel (ortholog); regulation of skeletal muscle contraction by calcium ion signal ing (ortholog); ASSOCIATED WITH long QT syndrome (ortholog); FOUND IN I band (inferred); T-tubule (inferred) | | | | Pig | 18 | name | gene, protein-coding, MODEL [RefSeq] |
| 18457023 | REM1 | RRAD and GEM like GTPase 1 | ENCODES a protein that exhibits calcium channel regulator activity (inferred); calmodulin binding (inferred); GTP binding (inferred); INVOLVED IN negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel (ortholog); regulation of skeletal muscle contraction by calcium ion signaling (ortholog); ASSOCIATED WITH long QT syndrome (ortholog); FOUND IN I band (inferred); plasma membrane (inferred); T-tubule (inferred) | | | | Green Monkey | 18 | name | gene, protein-coding, MODEL [RefSeq] |
| 18917198 | Rem1 | RRAD and GEM like GTPase 1 | ENCODES a protein that exhibits transmembrane transporter binding (ortholog); INVOLVED IN negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel (ortholog); regulation of skeletal muscle contraction by calcium ion signaling (ortholog); ASSOCIATED WITH long QT syndrome (ortholog); FOUND IN I band (ortholog); T-tubule (ortholog) | | | | Naked Mole-Rat | 18 | name | gene, protein-coding, MODEL [RefSeq] |
| 626000660 | Rem1 | RRAD and GEM like GTPase 1 | ENCODES a protein that exhibits transmembrane transporter binding (ortholog); INVOLVED IN negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel (ortholog); regulation of skeletal muscle contraction by calcium ion signaling (ortholog); ASSOCIATED WITH long QT syndrome (ortholog); FOUND IN I band (ortholog); T-tubule (ortholog) | | | | Black Rat | 7 | name | gene, protein-coding, MODEL [RefSeq] |
| 69081 | Rem2 | RRAD and GEM like GTPase 2 | ENCODES a protein that exhibits GTP binding; GTPase activity; FOUND IN plasma membrane (inferred); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 15 | 31903972 | 31908451 | Rat | 76 | name | gene, protein-coding, VALIDATED [RefSeq] |
| 733550 | REM2 | RRAD and GEM like GTPase 2 | Predicted to enable GTP binding activity and calcium channel regulator activity. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025] | 14 | 22883222 | 22887678 | Human | 78 | name | gene, protein-coding, VALIDATED [RefSeq] |
| 8968557 | Rem2 | RRAD and GEM like GTPase 2 | ENCODES a protein that exhibits GTP binding (ortholog); GTPase activity (ortholog) | NW_004955409 | 37403758 | 37408312 | Chinchilla | 3 | name | gene, protein-coding, MODEL [RefSeq] |
| 11919030 | REM2 | RRAD and GEM like GTPase 2 | ENCODES a protein that exhibits GTP binding (ortholog); GTPase activity (ortholog); FOUND IN plasma membrane (inferred) | 14 | 3700397 | 3704897 | Bonobo | 11 | name | gene, protein-coding, MODEL [RefSeq] |
| 12218529 | REM2 | RRAD and GEM like GTPase 2 | ENCODES a protein that exhibits GTP binding (ortholog); GTPase activity (ortholog); INVOLVED IN endocytosis (inferred); vesicle-mediated transport (inferred); FOUND IN clathrin-coated pit (inferred); membrane (inferred); plasma membrane (inferred) | 8 | 3215023 | 3223470 | Dog | 17 | name | gene, protein-coding, MODEL [RefSeq] |
| 12597345 | Rem2 | RRAD and GEM like GTPase 2 | ENCODES a protein that exhibits GTP binding (ortholog); GTPase activity (ortholog); FOUND IN plasma membrane (inferred) | NW_004936722 | 1412068 | 1416967 | Squirrel | 11 | name | gene, protein-coding, MODEL [RefSeq] |
| 13959347 | REM2 | RRAD and GEM like GTPase 2 | ENCODES a protein that exhibits GTP binding (ortholog); GTPase activity (ortholog); FOUND IN plasma membrane (inferred); INTERACTS WITH graphene oxide | | | | Pig | 12 | name | gene, protein-coding, MODEL [RefSeq] |
| 18368622 | REM2 | RRAD and GEM like GTPase 2 | ENCODES a protein that exhibits GTP binding (ortholog); GTPase activity (ortholog); FOUND IN plasma membrane (inferred) | | | | Green Monkey | 11 | name | gene, protein-coding, MODEL [RefSeq] |
| 18924201 | Rem2 | RRAD and GEM like GTPase 2 | ENCODES a protein that exhibits GTP binding (ortholog); GTPase activity (ortholog); FOUND IN plasma membrane (inferred) | | | | Naked Mole-Rat | 11 | name | gene, protein-coding, MODEL [RefSeq] |
| 625844723 | Rem2 | RRAD and GEM like GTPase 2 | ENCODES a protein that exhibits GTP binding (ortholog); GTPase activity (ortholog) | | | | Black Rat | 3 | name | gene, protein-coding, MODEL [RefSeq] |
| 1315249 | Rem1 | rad and gem related GTP binding protein 1 | Enables transmembrane transporter binding activity. Acts upstream of or within negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel and regulation of skeletal muscle contraction by calcium ion signaling. Located in I band and T-tubule. Is expressed in ali mentary system and urinary system. Orthologous to human REM1 (RRAD and GEM like GTPase 1). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 152468928 | 152477111 | Mouse | 50 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 733551 | Rem2 | rad and gem related GTP binding protein 2 | Predicted to enable GTP binding activity; GTPase activity; and calcium channel regulator activity. Predicted to be active in plasma membrane. Is expressed in central nervous system; epithelium; and limb. Orthologous to human REM2 (RRAD and GEM like GTPase 2). [p rovided by Alliance of Genome Resources, Apr 2025] | 14 | 54713676 | 54717889 | Mouse | 89 | description | gene, protein-coding, VALIDATED [RefSeq] |