Rem1 (RRAD and GEM like GTPase 1) - Rat Genome Database

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Gene: Rem1 (RRAD and GEM like GTPase 1) Ictidomys tridecemlineatus
Analyze
Symbol: Rem1
Name: RRAD and GEM like GTPase 1
RGD ID: 12591240
Description: ENCODES a protein that exhibits calcium channel regulator activity (inferred); calmodulin binding (inferred); GTP binding (inferred); INVOLVED IN negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel (ortholog); regulation of skeletal muscle contraction by calcium ion signaling (ortholog); ASSOCIATED WITH long QT syndrome (ortholog); FOUND IN I band (inferred); plasma membrane (inferred); T-tubule (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: GTP-binding protein REM 1; RRAD and GEM like GTPase 1, transcript variant X1; RRAD and GEM like GTPase 1, transcript variant X2; RRAD and GEM like GTPase 1, transcript variant X3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640170,072,661 - 170,081,403 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648518,504,014 - 18,512,783 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648518,504,086 - 18,512,761 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
I band  (IEA)
plasma membrane  (IEA)
T-tubule  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Rem1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640170,072,661 - 170,081,403 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648518,504,014 - 18,512,783 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648518,504,086 - 18,512,761 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
REM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382031,475,288 - 31,484,895 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2031,475,288 - 31,484,895 (+)EnsemblGRCh38hg38GRCh38
GRCh372030,063,091 - 30,072,698 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362029,526,766 - 29,536,369 (+)NCBINCBI36Build 36hg18NCBI36
Build 342029,526,765 - 29,536,368NCBI
Celera2026,819,299 - 26,828,898 (+)NCBICelera
Cytogenetic Map20q11.21NCBI
HuRef2026,851,232 - 26,860,903 (+)NCBIHuRef
CHM1_12029,966,984 - 29,976,601 (+)NCBICHM1_1
T2T-CHM13v2.02033,199,537 - 33,209,122 (+)NCBIT2T-CHM13v2.0
Rem1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392152,468,928 - 152,477,111 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2152,468,871 - 152,477,118 (+)EnsemblGRCm39 Ensembl
GRCm382152,627,008 - 152,635,191 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2152,626,951 - 152,635,198 (+)EnsemblGRCm38mm10GRCm38
MGSCv372152,452,744 - 152,460,927 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362152,318,449 - 152,326,632 (+)NCBIMGSCv36mm8
Celera2158,443,011 - 158,451,149 (+)NCBICelera
Cytogenetic Map2H1NCBI
cM Map275.41NCBI
Rem1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83161,563,984 - 161,572,478 (+)NCBIGRCr8
mRatBN7.23141,103,722 - 141,112,206 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3141,103,766 - 141,112,203 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3145,008,741 - 145,017,183 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03153,592,584 - 153,601,026 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03151,332,633 - 151,341,104 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03148,108,500 - 148,116,992 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3148,108,539 - 148,116,991 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03154,513,659 - 154,522,147 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43142,976,928 - 142,985,368 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13142,882,500 - 142,890,941 (+)NCBI
Celera3139,853,348 - 139,861,792 (+)NCBICelera
Cytogenetic Map3q41NCBI
Rem1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542229,429,908 - 29,443,273 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542229,434,477 - 29,443,172 (-)NCBIChiLan1.0ChiLan1.0
REM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22137,166,505 - 37,176,131 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12037,159,583 - 37,169,228 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02027,764,390 - 27,774,026 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12028,402,187 - 28,410,826 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2028,402,181 - 28,415,090 (+)Ensemblpanpan1.1panPan2
REM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12420,991,166 - 21,000,019 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2420,990,745 - 20,999,740 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2420,639,145 - 20,648,011 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02421,677,955 - 21,686,825 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2421,677,920 - 21,686,546 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12420,956,311 - 20,965,190 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02421,061,548 - 21,070,421 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02421,491,764 - 21,500,627 (+)NCBIUU_Cfam_GSD_1.0
REM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1735,208,363 - 35,218,768 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11735,208,344 - 35,218,771 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21739,851,229 - 39,854,111 (-)NCBISscrofa10.2Sscrofa10.2susScr3
REM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1235,887,264 - 35,897,432 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl235,887,658 - 35,898,312 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605091,060,938 - 91,070,938 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rem1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624741997,093 - 1,007,273 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624741997,307 - 1,007,267 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000028282   ⟹   ENSSTOP00000021631
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493648518,504,014 - 18,512,783 (+)Ensembl
RefSeq Acc Id: XM_013356447   ⟹   XP_013211901
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640170,072,661 - 170,081,403 (+)NCBI
SpeTri2.0NW_00493648518,504,097 - 18,512,761 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021723238   ⟹   XP_021578913
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640170,072,661 - 170,081,403 (+)NCBI
SpeTri2.0NW_00493648518,504,086 - 18,512,761 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021723239   ⟹   XP_021578914
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640170,072,661 - 170,081,403 (+)NCBI
SpeTri2.0NW_00493648518,504,086 - 18,512,761 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040275274   ⟹   XP_040131208
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640170,073,144 - 170,081,403 (+)NCBI
RefSeq Acc Id: XM_040275275   ⟹   XP_040131209
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640170,073,144 - 170,081,403 (+)NCBI
RefSeq Acc Id: XM_040275276   ⟹   XP_040131210
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640170,072,661 - 170,081,403 (+)NCBI
RefSeq Acc Id: XM_040275277   ⟹   XP_040131211
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640170,072,661 - 170,081,403 (+)NCBI
RefSeq Acc Id: XP_013211901   ⟸   XM_013356447
- Peptide Label: isoform X1
- UniProtKB: I3NB84 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021578913   ⟸   XM_021723238
- Peptide Label: isoform X1
- UniProtKB: I3NB84 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021578914   ⟸   XM_021723239
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_040131210   ⟸   XM_040275276
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040131211   ⟸   XM_040275277
- Peptide Label: isoform X4
RefSeq Acc Id: XP_040131208   ⟸   XM_040275274
- Peptide Label: isoform X1
- UniProtKB: I3NB84 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040131209   ⟸   XM_040275275
- Peptide Label: isoform X1
- UniProtKB: I3NB84 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSSTOP00000021631   ⟸   ENSSTOT00000028282


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000022897 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000028282.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  RGK UniProtKB/TrEMBL
  RGK_GTP-binding_reg UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
NCBI Gene Rem1 ENTREZGENE
PANTHER GTP-BINDING PROTEIN REM 1 UniProtKB/TrEMBL
  RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PIRSF GTP-binding_GEM UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
SMART RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt I3NB84 ENTREZGENE, UniProtKB/TrEMBL