| 735222 | Nob1 | NIN1 (RPN12) binding protein 1 homolog | ENCODES a protein that exhibits RNA endonuclease activity (ortholog); INVOLVED IN visual perception (ortholog); PARTICIPATES IN ribosome biogenesis pathway; ASSOCIATED WITH Hearing Loss, Noise-Induced; FOUND IN nucleus (inferred); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-t etrachlorodibenzodioxine | 19 | 52232543 | 52245824 | Rat | 99 | symbol , old_gene_name , PhenoGen , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1553773 | Nob1 | NIN1/RPN12 binding protein 1 homolog | Predicted to enable RNA endonuclease activity. Acts upstream of or within visual perception. Predicted to be located in cytoplasm and nucleolus. Predicted to be part of preribosome, small subunit precursor. Is expressed in nervous system and neural retina. Orthologous to human NOB1 ht:700;'>NOB1 (NIN1 (RPN12) binding protein 1 homolog). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 108139121 | 108151670 | Mouse | 101 | symbol , old_gene_name , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1603053 | NOB1 | NIN1 (RPN12) binding protein 1 homolog | In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and bindin g of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 [PubMed 19706509]).[supplied by OMIM, Nov 2010] | 16 | 69741871 | 69754926 | Human | 101 | symbol , old_gene_name , COSMIC , description , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8931810 | Nob1 | NIN1 (RPN12) binding protein 1 homolog | ENCODES a protein that exhibits RNA endonuclease activity (ortholog); INVOLVED IN visual perception (ortholog); PARTICIPATES IN ribosome biogenesis pathway; ASSOCIATED WITH Hearing Loss, Noise-Induced (ortholog) | NW_004955484 | 6996795 | 7006499 | Chinchilla | 5 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11853836 | NOB1 | NIN1 (RPN12) binding protein 1 homolog | ENCODES a protein that exhibits endonuclease activity (inferred); hydrolase activity (inferred); metal ion binding (inferred); INVOLVED IN visual perception (ortholog); PARTICIPATES IN ribosome biogenesis pathway; ASSOCIATED WITH Hearing Loss, Noise-Induced (ortholog); FOUND IN nucleus (inferred); p reribosome, small subunit precursor (inferred) | 16 | 50122905 | 50135096 | Bonobo | 17 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12060430 | NOB1 | NIN1 (RPN12) binding protein 1 homolog | ENCODES a protein that exhibits endonuclease activity (inferred); hydrolase activity (inferred); metal ion binding (inferred); INVOLVED IN visual perception (ortholog); PARTICIPATES IN ribosome biogenesis pathway; ASSOCIATED WITH Hearing Loss, Noise-Induced (ortholog); FOUND IN nucleus (inferred) | 5 | 79958145 | 79966166 | Dog | 17 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12629260 | Nob1 | NIN1 (RPN12) binding protein 1 homolog | ENCODES a protein that exhibits endonuclease activity (inferred); hydrolase activity (inferred); metal ion binding (inferred); INVOLVED IN visual perception (ortholog); PARTICIPATES IN ribosome biogenesis pathway; ASSOCIATED WITH Hearing Loss, Noise-Induced (ortholog); FOUND IN nucleus (inferred); p reribosome, small subunit precursor (inferred) | NW_004936475 | 19794199 | 19808142 | Squirrel | 17 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 14038700 | NOB1 | NIN1 (RPN12) binding protein 1 homolog | ENCODES a protein that exhibits endonuclease activity (inferred); hydrolase activity (inferred); metal ion binding (inferred); INVOLVED IN visual perception (ortholog); PARTICIPATES IN ribosome biogenesis pathway; ASSOCIATED WITH Hearing Loss, Noise-Induced (ortholog); FOUND IN nucleus (inferred) | | | | Pig | 17 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 14374829 | NOB1 | | | | | | Yeast | | symbol | gene, null |
| 18695467 | NOB1 | NIN1 (RPN12) binding protein 1 homolog | ENCODES a protein that exhibits endonuclease activity (inferred); hydrolase activity (inferred); metal ion binding (inferred); INVOLVED IN visual perception (ortholog); PARTICIPATES IN ribosome biogenesis pathway; ASSOCIATED WITH Hearing Loss, Noise-Induced (ortholog); FOUND IN nucleus (inferred); p reribosome, small subunit precursor (inferred) | | | | Green Monkey | 17 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18902062 | Nob1 | NIN1 (RPN12) binding protein 1 homolog | ENCODES a protein that exhibits endonuclease activity (inferred); hydrolase activity (inferred); metal ion binding (inferred); INVOLVED IN visual perception (ortholog); PARTICIPATES IN ribosome biogenesis pathway; ASSOCIATED WITH Hearing Loss, Noise-Induced (ortholog); FOUND IN nucleus (inferred); p reribosome, small subunit precursor (inferred) | | | | Naked Mole-Rat | 17 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155251862 | nob1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626108028 | Nob1 | NIN1 (RPN12) binding protein 1 homolog | ENCODES a protein that exhibits RNA endonuclease activity (ortholog); INVOLVED IN visual perception (ortholog); PARTICIPATES IN ribosome biogenesis pathway; ASSOCIATED WITH Hearing Loss, Noise-Induced (ortholog) | | | | Black Rat | 5 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155250928 | nob1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1312071 | Tbc1d1 | TBC1 domain family, member 1 | Predicted to enable GTPase activator activity. Predicted to be involved in negative regulation of insulin secretion involved in cellular response to glucose stimulus. Predicted to be located in cytosol. Predicted to be active in Golgi apparatus. Is expressed in several structures, including adrenal medulla; brain; genitourinary system; gut gland; and retina. Orthologous to human TBC1D1 (TBC1 domain family member 1). [provided by Alliance of Genome Resources, Jul 2025] | 5 | 64313648 | 64508829 | Mouse | 140 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 727882 | Pno1 | partner of NOB1 homolog | ENCODES a protein that exhibits nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN ribosomal small subunit biogenesis (ortholog); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN nucleolus (ortholog); small-subunit processome (ortholog); INTERACTS WITH (+)-schisandrin B; 4,4'- sulfonyldiphenol; 6-propyl-2-thiouracil | 14 | 95811335 | 95819903 | Rat | 101 | old_gene_name , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1553017 | Pno1 | partner of NOB1 homolog | Predicted to enable RNA binding activity. Predicted to be involved in ribosomal small subunit biogenesis. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of small-subunit processome. Predicted to be active in nucleus. Is expressed in several structures, including adrenal g land; alimentary system; central nervous system; heart; and immune system. Orthologous to human PNO1 (partner of NOB1 homolog). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 17153198 | 17161589 | Mouse | 111 | name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1604334 | PNO1 | partner of NOB1 homolog | Enables RNA binding activity. Involved in ribosomal small subunit biogenesis. Located in nucleolus and nucleoplasm. Part of small-subunit processome. [provided by Alliance of Genome Resources, Jul 2025] | 2 | 68157888 | 68176238 | Human | 104 | name | gene, protein-coding, VALIDATED [RefSeq] |
| 8779551 | Pno1 | partner of NOB1 homolog | INVOLVED IN ribosomal small subunit biogenesis (ortholog); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN nucleolus (ortholog); small-subunit processome (ortholog) | NW_004955424 | 16697109 | 16705963 | Chinchilla | 7 | name | gene, protein-coding, MODEL [RefSeq] |
| 12196785 | PNO1 | partner of NOB1 homolog | ENCODES a protein that exhibits nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN ribosomal small subunit biogenesis (inferred); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN nucleolus (inferred); small-subunit processome (inferred) | 10 | 67231087 | 67241800 | Dog | 13 | name | gene, protein-coding, MODEL [RefSeq] |
| 12474283 | Pno1 | partner of NOB1 homolog | ENCODES a protein that exhibits nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN ribosomal small subunit biogenesis (inferred); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN nucleolus (inferred); nucleus (inferred); small-subunit processome (inferred) | NW_004936491 | 12610463 | 12620828 | Squirrel | 13 | name | gene, protein-coding, MODEL [RefSeq] |
| 14165024 | PNO1 | partner of NOB1 homolog | ENCODES a protein that exhibits nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN ribosomal small subunit biogenesis (inferred); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN nucleolus (inferred); small-subunit processome (inferred) | | | | Pig | 13 | name | gene, protein-coding, MODEL [RefSeq] |
| 18576291 | PNO1 | partner of NOB1 homolog | ENCODES a protein that exhibits nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN ribosomal small subunit biogenesis (inferred); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN nucleolus (inferred); nucleus (inferred); small-subunit processome (inferred) | | | | Green Monkey | 13 | name | gene, protein-coding, MODEL [RefSeq] |
| 18916105 | Pno1 | partner of NOB1 homolog | ENCODES a protein that exhibits nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN ribosomal small subunit biogenesis (inferred); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN nucleolus (inferred); nucleus (inferred); small-subunit processome (inferred) | | | | Naked Mole-Rat | 13 | name | gene, protein-coding, MODEL [RefSeq] |
| 20420529 | PNO1 | partner of NOB1 homolog | ENCODES a protein that exhibits RNA binding (inferred); FOUND IN nucleus (inferred) | | | | Bonobo | 2 | name | gene, protein-coding |
| 32729819 | PNO1 | partner of NOB1 homolog | ENCODES a protein that exhibits nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN ribosomal small subunit biogenesis (inferred); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN nucleolus (inferred); nucleus (inferred); small-subunit processome (inferred) | 2A | 68209911 | 68224772 | Bonobo | 13 | name | gene, protein-coding, MODEL [RefSeq] |
| 625841312 | Pno1 | partner of NOB1 homolog | INVOLVED IN ribosomal small subunit biogenesis (ortholog); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN nucleolus (ortholog); small-subunit processome (ortholog) | | | | Black Rat | 7 | name | gene, protein-coding, MODEL [RefSeq] |
| 11681994 | LOC100978496 | RNA-binding protein NOB1-like | | 4 | 130918803 | 130920121 | Bonobo | | old_gene_name , name | gene, pseudo, MODEL [RefSeq] |
| 8764864 | LOC102005878 | RNA-binding protein NOB1-like | | NW_004957102 | 190 | 886 | Chinchilla | | name | gene, protein-coding, MODEL [RefSeq] |
| 1590900 | Pno1-ps1 | partner of NOB1 homolog (S. cerevisiae), pseudogene 1 | INTERACTS WITH atrazine | 10 | 87846176 | 87847446 | Rat | 1 | old_gene_name , name | gene, pseudo, INFERRED [RefSeq] |
| 16565464 | AC087283.1 | partner of NOB1 homolog (S. cerevisiae) (PNO1) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16558283 | AC098859.1 | NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) (NOB1) pseudogene | | | | | Human | | name | gene, processed_pseudogene |