Ndrg1 Gene Search Result

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16 records found for search term Ndrg1

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1307303	Ndrg1	N-myc downstream regulated 1	ENCODES a protein that exhibits cadherin binding (ortholog); gamma-tubulin binding (ortholog); microtubule binding (ortholog); INVOLVED IN cellular response to hypoxia (ortholog); DNA damage response, signal transduction by p53 class mediator (ortholog); mast cell activation (ortholog); PARTICIPATES ... (more) IN hypoxia inducible factor pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Charcot-Marie-Tooth disease (ortholog); Charcot-Marie-Tooth disease type 4 (ortholog); FOUND IN adherens junction (ortholog); centrosome (ortholog); cytoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 1-benzylpiperazine; 1-naphthyl isothiocyanate	7	100573526	100614902	Rat	428	symbol , PhenoGen	gene, protein-coding, PROVISIONAL [RefSeq]
1316419	NDRG1	N-myc downstream regulated 1	This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-me ... (more) diated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]	8	133237175	133297252	Human	532	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1316420	Ndrg1	N-myc downstream regulated gene 1	Predicted to enable cadherin binding activity; small GTPase binding activity; and tubulin binding activity. Involved in negative regulation of cell population proliferation and peripheral nervous system myelin maintenance. Acts upstream of or within mast cell activation. Located in cytoplasm. Is exp ... (more) ressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and sensory organ. Used to study Charcot-Marie-Tooth disease type 4D. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4D. Orthologous to human NDRG1 (N-myc downstream regulated 1). [provided by Alliance of Genome Resources, Apr 2025]	15	66801167	66841490	Mouse	473	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
8932454	Ndrg1	N-myc downstream regulated 1	ENCODES a protein that exhibits cadherin binding (ortholog); gamma-tubulin binding (ortholog); microtubule binding (ortholog); INVOLVED IN cellular response to hypoxia (ortholog); DNA damage response, signal transduction by p53 class mediator (ortholog); mast cell activation (ortholog); PARTICIPATES ... (more) IN hypoxia inducible factor pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Charcot-Marie-Tooth disease (ortholog); Charcot-Marie-Tooth disease type 4 (ortholog); FOUND IN adherens junction (ortholog); centrosome (ortholog); cytoplasm (ortholog)	NW_004955461	7787068	7836380	Chinchilla	55	symbol	gene, protein-coding, MODEL [RefSeq]
12026641	NDRG1	N-myc downstream regulated 1	ENCODES a protein that exhibits cadherin binding (inferred); gamma-tubulin binding (inferred); microtubule binding (inferred); INVOLVED IN mast cell activation (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Charcot-Marie-Tooth disease (orth ... (more) olog); Charcot-Marie-Tooth disease type 4 (ortholog); FOUND IN adherens junction (inferred); centrosome (inferred); cytoplasm (inferred)	8	129891918	129952489	Bonobo	53	symbol	gene, protein-coding, MODEL [RefSeq]
12205150	NDRG1	N-myc downstream regulated 1	ENCODES a protein that exhibits cadherin binding (inferred); gamma-tubulin binding (inferred); microtubule binding (inferred); INVOLVED IN mast cell activation (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; ASSOCIATED WITH Charcot-Marie-Tooth disease type 4D; Breast Neoplasms (ortholo ... (more) g); Charcot-Marie-Tooth disease (ortholog); FOUND IN adherens junction (inferred); centrosome (inferred); cytoplasm (inferred)	13	29689294	29745964	Dog	63	symbol , old_gene_name	gene, protein-coding, PROVISIONAL [RefSeq]
12446122	Ndrg1	N-myc downstream regulated 1	ENCODES a protein that exhibits cadherin binding (inferred); gamma-tubulin binding (inferred); microtubule binding (inferred); INVOLVED IN mast cell activation (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Charcot-Marie-Tooth disease (orth ... (more) olog); Charcot-Marie-Tooth disease type 4 (ortholog); FOUND IN adherens junction (inferred); centrosome (inferred); cytoplasm (inferred)	NW_004936470	16051291	16102563	Squirrel	53	symbol	gene, protein-coding, MODEL [RefSeq]
14022045	NDRG1	N-myc downstream regulated 1	ENCODES a protein that exhibits cadherin binding (inferred); gamma-tubulin binding (inferred); microtubule binding (inferred); INVOLVED IN mast cell activation (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Charcot-Marie-Tooth disease (orth ... (more) olog); Charcot-Marie-Tooth disease type 4 (ortholog); FOUND IN adherens junction (inferred); centrosome (inferred); cytoplasm (inferred); INTERACTS WITH graphene oxide				Pig	63	symbol , old_gene_name	gene, protein-coding, MODEL [RefSeq]
625874443	Ndrg1	N-myc downstream regulated 1	ENCODES a protein that exhibits cadherin binding (ortholog); gamma-tubulin binding (ortholog); microtubule binding (ortholog); INVOLVED IN cellular response to hypoxia (ortholog); DNA damage response, signal transduction by p53 class mediator (ortholog); mast cell activation (ortholog); PARTICIPATES ... (more) IN hypoxia inducible factor pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Charcot-Marie-Tooth disease (ortholog); Charcot-Marie-Tooth disease type 4 (ortholog); FOUND IN adherens junction (ortholog); centrosome (ortholog); cytoplasm (ortholog)				Black Rat	52	symbol , old_gene_name	gene, protein-coding, MODEL [RefSeq]
155239767	ndrg1						Tropical Clawed Frog		symbol	gene, null
18930203	Ndrg1	N-myc downstream regulated 1	ENCODES a protein that exhibits cadherin binding (ortholog); gamma-tubulin binding (ortholog); microtubule binding (ortholog); INVOLVED IN cellular response to hypoxia (ortholog); DNA damage response, signal transduction by p53 class mediator (ortholog); mast cell activation (ortholog); PARTICIPATES ... (more) IN hypoxia inducible factor pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Charcot-Marie-Tooth disease (ortholog); Charcot-Marie-Tooth disease type 4 (ortholog); FOUND IN adherens junction (ortholog); centrosome (ortholog); cytoplasm (ortholog)				Naked Mole-Rat	55	symbol , old_gene_name	gene, protein-coding, MODEL [RefSeq]
18737228	NDRG1	N-myc downstream regulated 1	ENCODES a protein that exhibits cadherin binding (inferred); gamma-tubulin binding (inferred); microtubule binding (inferred); INVOLVED IN mast cell activation (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Charcot-Marie-Tooth disease (orth ... (more) olog); Charcot-Marie-Tooth disease type 4 (ortholog); FOUND IN adherens junction (inferred); centrosome (inferred); cytoplasm (inferred)				Green Monkey	53	symbol , old_gene_name	gene, protein-coding, MODEL [RefSeq]
155236665	ndrg1.L						African Clawed Frog		symbol	gene, null
155239768	ndrg1.S						African Clawed Frog		symbol	gene, null
621874	Ndrg2	NDRG family member 2	INVOLVED IN negative regulation of cytokine production (ortholog); negative regulation of ERK1 and ERK2 cascade (ortholog); negative regulation of smooth muscle cell proliferation (ortholog); ASSOCIATED WITH cataract (ortholog); Colonic Neoplasms (ortholog); Experimental Liver Cirrhosis (ortholog); ... (more) FOUND IN cytoplasm (ortholog); cytosol (ortholog); Golgi apparatus (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol	15	27074481	27087376	Rat	235	old_gene_name	gene, protein-coding, VALIDATED [RefSeq]
1348469	ERG	ETS transcription factor ERG	This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is m ... (more) ainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. More than two dozens of transcript variants generated from combinatorial usage of three alternative promoters and multiple alternative splicing events have been reported, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Apr 2014]	21	38367261	38661783	Human	143	description	gene, protein-coding, REVIEWED [RefSeq]