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28 records found for search term Lgals3
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
69356Lgals3galectin 3ENCODES a protein that exhibits advanced glycation end-product receptor activity; disaccharide binding; Fc-gamma receptor I complex binding; INVOLVED IN negative regulation of apoptotic process; negative regulation of cell proliferation in bone marrow; positive regulation of angiogenesis; PARTICIPAT152309979523111731Rat460symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
736304LGALS3galectin 3This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. 145512925255145430Human444symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
736305Lgals3lectin, galactose binding, soluble 3Predicted to enable several functions, including IgE binding activity; advanced glycation end-product receptor activity; and signaling receptor binding activity. Involved in negative regulation of T cell receptor signaling pathway; negative regulation of endocytosis; and negative regulation of lymph144761131747623624Mouse531symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
9030206Lgals3galectin 3ENCODES a protein that exhibits advanced glycation end-product receptor activity (ortholog); carbohydrate binding (ortholog); chemoattractant activity (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); eosinophil chemotaxis (ortholog); epithelNW_00495540984481208452437Chinchilla124symbolgene, protein-coding, MODEL [RefSeq]
11743189LGALS3galectin 3ENCODES a protein that exhibits advanced glycation end-product receptor activity (ortholog); disaccharide binding (ortholog); Fc-gamma receptor I complex binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); extracellular matrix organizat143571585035732263Bonobo148symbolgene, protein-coding, MODEL [RefSeq]
12412971LGALS3galectin 3ENCODES a protein that exhibits advanced glycation end-product receptor activity (ortholog); disaccharide binding (ortholog); Fc-gamma receptor I complex binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); extracellular matrix organizat83097743830994711Dog148symbolgene, protein-coding, VALIDATED [RefSeq]
12703013Lgals3galectin 3ENCODES a protein that exhibits advanced glycation end-product receptor activity (ortholog); disaccharide binding (ortholog); Fc-gamma receptor I complex binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); extracellular matrix organizatNW_0049366972086138568Squirrel148symbolgene, protein-coding, MODEL [RefSeq]
18920227Lgals3galectin 3ENCODES a protein that exhibits advanced glycation end-product receptor activity (ortholog); chemoattractant activity (ortholog); disaccharide binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); epithelial cell differentiation (orthologNaked Mole-Rat135symbolgene, protein-coding, MODEL [RefSeq]
14055434LGALS3galectin 3ENCODES a protein that exhibits advanced glycation end-product receptor activity (ortholog); disaccharide binding (ortholog); Fc-gamma receptor I complex binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); extracellular matrix organizatPig149symbolgene, protein-coding, PROVISIONAL [RefSeq]
18569712LGALS3galectin 3ENCODES a protein that exhibits advanced glycation end-product receptor activity (ortholog); disaccharide binding (ortholog); Fc-gamma receptor I complex binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); extracellular matrix organizatGreen Monkey148symbolgene, protein-coding, MODEL [RefSeq]
626059930Lgals3galectin 3ENCODES a protein that exhibits advanced glycation end-product receptor activity (ortholog); carbohydrate binding (ortholog); chemoattractant activity (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); eosinophil chemotaxis (ortholog); epithelBlack Rat124symbolgene, protein-coding, MODEL [RefSeq]
155232768lgals3Tropical Clawed Frogsymbolgene, null
155251887lgals3.LAfrican Clawed Frogsymbolgene, null
155236067lgals3.SAfrican Clawed Frogsymbolgene, null
626419691Lgals3em1Dfultgalectin 3; endonuclease induced mutant 1, DfultCRISPR technology was used on the Sprague-Dawley background (Sage) to edit Lgals3 genome. CRISPR guides were selected targeting the fifth exon, and gene disruption was confirmed by genomic sequencing and immunoblot analysis for Gal-3 protein expression in lung tRatsymbol , descriptiongene, allele
620837Lgals3bpgalectin 3 binding proteinINVOLVED IN cell adhesion (inferred); ASSOCIATED WITH liver cirrhosis (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 17beta-estradiol 3-benzoate10104118510104127848Rat186symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
734457Lgals3bplectin, galactoside-binding, soluble, 3 binding proteinPredicted to enable scavenger receptor activity. Predicted to be involved in cell adhesion and vesicle-mediated transport. Located in extracellular space. Is expressed in several structures, including brain; genitourinary system; gut; integumental system; and liver and biliary system. Orthologous to11118283573118292787Mouse194symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
1352457LGALS3BPgalectin 3 binding proteinThe galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV)177897125578979923Human204symbol , COSMIC , description , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
8925934Lgals3bpgalectin 3 binding proteinASSOCIATED WITH liver cirrhosis (ortholog); FOUND IN extracellular space (ortholog)NW_00495550637318103741314Chinchilla13symbolgene, protein-coding, MODEL [RefSeq]
11694592LGALS3BPgalectin 3 binding proteinINVOLVED IN cell adhesion (inferred); ASSOCIATED WITH liver cirrhosis (ortholog); FOUND IN extracellular matrix (inferred); extracellular space (inferred); membrane (inferred)177304777773056431Bonobo17symbolgene, protein-coding, MODEL [RefSeq]
12493723Lgals3bpgalectin 3 binding proteinASSOCIATED WITH liver cirrhosis (ortholog); FOUND IN extracellular matrix (inferred); extracellular region (inferred); extracellular space (inferred)NW_00493659433038623316313Squirrel17symbolgene, protein-coding, MODEL [RefSeq]
18769678LGALS3BPgalectin 3 binding proteinINVOLVED IN cell adhesion (inferred); ASSOCIATED WITH liver cirrhosis (ortholog); FOUND IN extracellular matrix (inferred); extracellular space (inferred); membrane (inferred)Green Monkey17symbolgene, protein-coding, MODEL [RefSeq]
625873048Lgals3bpgalectin 3 binding proteinASSOCIATED WITH liver cirrhosis (ortholog); FOUND IN extracellular space (ortholog)Black Rat13symbolgene, protein-coding, MODEL [RefSeq]
14061091LGALS3BPgalectin 3 binding proteinINVOLVED IN cell adhesion (inferred); ASSOCIATED WITH liver cirrhosis (ortholog); FOUND IN extracellular space (inferred); membrane (inferred); INTERACTS WITH deoxynivalenolPig18symbolgene, protein-coding, MODEL [RefSeq]
18925182Lgals3bpgalectin 3 binding proteinASSOCIATED WITH liver cirrhosis (ortholog); FOUND IN extracellular matrix (inferred); extracellular region (inferred); extracellular space (inferred)Naked Mole-Rat16symbolgene, protein-coding, MODEL [RefSeq]
10868Lgals9lectin, galactose binding, soluble 9Enables several functions, including carbohydrate binding activity; galactoside binding activity; and protein serine/threonine kinase activator activity. Involved in several processes, including regulation of cytokine production; regulation of defense response; and regulation of leukocyte activation117885380578875750Mouse250old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
12355615CANT1calcium activated nucleotidase 1ENCODES a protein that exhibits ADP phosphatase activity (ortholog); GDP phosphatase activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); proteoglycan biosynthetic process (ortholog); PARTICIPATES IN924281072460097Dog35old_gene_symbolgene, protein-coding, MODEL [RefSeq]
2301265BTBD17BTB domain containing 17Predicted to be involved in negative regulation of viral genome replication and response to virus. Predicted to be located in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]177435641674363327Human53old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]