LGALS3 (galectin 3) - Rat Genome Database

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Gene: LGALS3 (galectin 3) Pan paniscus
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Symbol: LGALS3
Name: galectin 3
RGD ID: 11743189
Description: ENCODES a protein that exhibits advanced glycation end-product receptor activity (ortholog); chemoattractant activity (ortholog); disaccharide binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); eosinophil chemotaxis (ortholog); epithelial cell differentiation (ortholog); PARTICIPATES IN Hedgehog signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); aortic valve stenosis (ortholog); asthma (ortholog); FOUND IN cell surface (ortholog); cornified envelope (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: galectin-3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11453,990,023 - 54,006,412 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1453,990,023 - 54,006,412 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01435,715,850 - 35,732,263 (+)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
antimicrobial humoral immune response mediated by antimicrobial peptide  (ISO)
eosinophil chemotaxis  (ISO)
epithelial cell differentiation  (ISO)
extracellular matrix organization  (ISO)
killing of cells of other organism  (ISO)
macrophage chemotaxis  (ISO)
maintenance of protein location  (ISO)
monocyte chemotaxis  (ISO)
mononuclear cell migration  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of cell proliferation in bone marrow  (ISO)
negative regulation of endocytosis  (ISO)
negative regulation of extrinsic apoptotic signaling pathway  (ISO)
negative regulation of immunological synapse formation  (ISO)
negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell  (ISO)
negative regulation of T cell receptor signaling pathway  (ISO)
neutrophil chemotaxis  (ISO)
positive chemotaxis  (ISO)
positive regulation of angiogenesis  (ISO)
positive regulation of calcium ion import  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of dendritic cell differentiation  (ISO)
positive regulation of mononuclear cell migration  (ISO)
positive regulation of protein localization to plasma membrane  (ISO)
positive regulation of protein-containing complex assembly  (ISO)
positive regulation of serotonin secretion  (ISO)
regulation of extrinsic apoptotic signaling pathway via death domain receptors  (ISO)
regulation of T cell apoptotic process  (ISO)
regulation of T cell proliferation  (ISO)
skeletal system development  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
LGALS3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11453,990,023 - 54,006,412 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1453,990,023 - 54,006,412 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01435,715,850 - 35,732,263 (+)NCBIMhudiblu_PPA_v0panPan3
LGALS3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1455,124,110 - 55,145,423 (+)EnsemblGRCh38hg38GRCh38
GRCh381455,129,252 - 55,145,430 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371455,595,970 - 55,612,148 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361454,665,625 - 54,681,901 (+)NCBINCBI36hg18NCBI36
Build 341454,665,757 - 54,681,881NCBI
Celera1435,645,428 - 35,661,641 (+)NCBI
Cytogenetic Map14q22.3NCBI
HuRef1435,758,537 - 35,774,750 (+)NCBIHuRef
CHM1_11455,534,573 - 55,550,756 (+)NCBICHM1_1
Lgals3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391447,611,317 - 47,623,624 (+)NCBIGRCm39mm39
GRCm39 Ensembl1447,605,208 - 47,623,617 (+)Ensembl
GRCm381447,373,860 - 47,386,167 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1447,367,751 - 47,386,160 (+)EnsemblGRCm38mm10GRCm38
MGSCv371447,993,535 - 48,005,842 (+)NCBIGRCm37mm9NCBIm37
MGSCv361446,295,795 - 46,308,037 (+)NCBImm8
Celera1443,562,063 - 43,575,064 (+)NCBICelera
Cytogenetic Map14C1NCBI
Lgals3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21520,620,083 - 20,632,019 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1520,607,692 - 20,632,025 (+)Ensembl
Rnor_6.01524,153,602 - 24,165,537 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1524,141,651 - 24,165,537 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01528,094,344 - 28,106,281 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41523,327,071 - 23,339,006NCBIRGSC3.4rn4RGSC3.4
Celera1521,014,742 - 21,026,522 (+)NCBICelera
Cytogenetic Map15p14NCBI
Lgals3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554098,447,774 - 8,452,438 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554098,448,120 - 8,452,437 (-)NCBIChiLan1.0ChiLan1.0
LGALS3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1830,977,438 - 30,994,711 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl830,983,633 - 30,994,705 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha830,752,177 - 30,763,224 (+)NCBI
ROS_Cfam_1.0831,236,480 - 31,254,738 (+)NCBI
UMICH_Zoey_3.1830,846,505 - 30,857,542 (+)NCBI
UNSW_CanFamBas_1.0830,923,589 - 30,934,646 (+)NCBI
UU_Cfam_GSD_1.0831,288,737 - 31,299,778 (+)NCBI
Lgals3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864074,252,712 - 74,264,450 (-)NCBI
SpeTri2.0NW_00493669720,861 - 38,568 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LGALS3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1184,478,710 - 184,497,951 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11184,478,639 - 184,496,155 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21204,956,478 - 204,974,108 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LGALS3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12432,311,343 - 32,328,335 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2432,311,271 - 32,328,339 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605320,546,585 - 20,562,993 (+)NCBIVero_WHO_p1.0
Lgals3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473114,300,138 - 14,307,843 (-)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000043198   ⟹   ENSPPAP00000020404
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1453,990,023 - 54,006,412 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000043206   ⟹   ENSPPAP00000020412
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1453,998,191 - 54,004,358 (+)Ensembl
RefSeq Acc Id: XM_003831687   ⟹   XP_003831735
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11453,990,029 - 54,006,412 (+)NCBI
Mhudiblu_PPA_v01435,715,850 - 35,732,263 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008957046   ⟹   XP_008955294
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11453,990,023 - 54,006,412 (+)NCBI
Mhudiblu_PPA_v01435,715,885 - 35,732,263 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008957047   ⟹   XP_008955295
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11453,990,281 - 54,006,412 (+)NCBI
Mhudiblu_PPA_v01435,716,194 - 35,732,263 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003831735 (Get FASTA)   NCBI Sequence Viewer  
  XP_008955294 (Get FASTA)   NCBI Sequence Viewer  
  XP_008955295 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_008955294   ⟸   XM_008957046
- Sequence:
RefSeq Acc Id: XP_003831735   ⟸   XM_003831687
- Sequence:
RefSeq Acc Id: XP_008955295   ⟸   XM_008957047
- Sequence:
RefSeq Acc Id: ENSPPAP00000020404   ⟸   ENSPPAT00000043198
RefSeq Acc Id: ENSPPAP00000020412   ⟸   ENSPPAT00000043206


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000033425 Ensembl, ENTREZGENE
Ensembl Protein ENSPPAP00000020404 ENTREZGENE
NCBI Gene LGALS3 ENTREZGENE