| 2858 | Id1 | inhibitor of DNA binding 1 | ENCODES a protein that exhibits identical protein binding; proteasome binding; transcription factor binding; INVOLVED IN cell-abiotic substrate adhesion; cellular response to dopamine; cellular response to epidermal growth factor stimulus; PARTICIPATES IN interleukin-3 signaling pathway; transformin g growth factor-beta superfamily mediated signaling pathway; ASSOCIATED WITH cholestasis; pulmonary hypertension; Spinal Cord Injuries; FOUND IN centrosome; cytoplasm (ortholog); nucleoplasm (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol | 3 | 161671525 | 161672691 | Rat | 462 | symbol , PhenoGen , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 736819 | ID1 | inhibitor of DNA binding 1 | The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | 20 | 31605289 | 31606510 | Human | 460 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1552283 | Id1 | inhibitor of DNA binding 1, HLH protein | Enables transcription regulator inhibitor activity. Involved in circadian rhythm; negative regulation of cold-induced thermogenesis; and regulation of gene expression. Acts upstream of or within several processes, including BMP signaling pathway; lung development; and negative regulation of macromol ecule biosynthetic process. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human ID1 (inhibitor of DNA binding 1). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 152578171 | 152579330 | Mouse | 549 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8732351 | Id1 | inhibitor of DNA binding 1, HLH protein | ENCODES a protein that exhibits identical protein binding (ortholog); proteasome binding (ortholog); transcription factor binding (ortholog); INVOLVED IN BMP signaling pathway (ortholog); cell-abiotic substrate adhesion (ortholog); cellular response to dopamine (ortholog); PARTICIPATES IN interleuki n-3 signaling pathway; ASSOCIATED WITH cholestasis (ortholog); disease of cellular proliferation (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); nucleoplasm (ortholog) | NW_004955422 | 29337969 | 29339178 | Chinchilla | 77 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11817453 | ID1 | inhibitor of DNA binding 1 | ENCODES a protein that exhibits identical protein binding (ortholog); proteasome binding (ortholog); transcription factor binding (ortholog); INVOLVED IN BMP signaling pathway (ortholog); cell-abiotic substrate adhesion (ortholog); cellular response to dopamine (ortholog); PARTICIPATES IN interleuki n-3 signaling pathway; ASSOCIATED WITH cholestasis (ortholog); disease of cellular proliferation (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN centrosome (ortholog) | 20 | 27895177 | 27896414 | Bonobo | 85 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12106872 | ID1 | inhibitor of DNA binding 1 | ENCODES a protein that exhibits identical protein binding (ortholog); proteasome binding (ortholog); transcription factor binding (ortholog); INVOLVED IN BMP signaling pathway (ortholog); cell-abiotic substrate adhesion (ortholog); cellular response to dopamine (ortholog); PARTICIPATES IN interleuki n-3 signaling pathway; ASSOCIATED WITH cholestasis (ortholog); disease of cellular proliferation (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN centrosome (ortholog); INTERACTS WITH bisphenol A | 24 | 21094339 | 21096276 | Dog | 87 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12642348 | Id1 | inhibitor of DNA binding 1, HLH protein | ENCODES a protein that exhibits identical protein binding (ortholog); proteasome binding (ortholog); transcription factor binding (ortholog); INVOLVED IN BMP signaling pathway (ortholog); cell-abiotic substrate adhesion (ortholog); cellular response to dopamine (ortholog); PARTICIPATES IN interleuki n-3 signaling pathway; ASSOCIATED WITH cholestasis (ortholog); disease of cellular proliferation (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN centrosome (ortholog) | NW_004936485 | 18610721 | 18611889 | Squirrel | 87 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18911653 | Id1 | inhibitor of DNA binding 1, HLH protein | ENCODES a protein that exhibits identical protein binding (ortholog); proteasome binding (ortholog); transcription factor binding (ortholog); INVOLVED IN BMP signaling pathway (ortholog); cell-abiotic substrate adhesion (ortholog); cellular response to dopamine (ortholog); PARTICIPATES IN interleuki n-3 signaling pathway; ASSOCIATED WITH cholestasis (ortholog); disease of cellular proliferation (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN centrosome (ortholog); nucleoplasm (ortholog) | | | | Naked Mole-Rat | 86 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625864912 | Id1 | inhibitor of DNA binding 1, HLH protein | ENCODES a protein that exhibits identical protein binding (ortholog); proteasome binding (ortholog); transcription factor binding (ortholog); INVOLVED IN BMP signaling pathway (ortholog); cell-abiotic substrate adhesion (ortholog); cellular response to dopamine (ortholog); PARTICIPATES IN interleuki n-3 signaling pathway; ASSOCIATED WITH cholestasis (ortholog); disease of cellular proliferation (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); nucleoplasm (ortholog) | | | | Black Rat | 77 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14254536 | ID1 | inhibitor of DNA binding 1 | ENCODES a protein that exhibits identical protein binding (ortholog); proteasome binding (ortholog); transcription factor binding (ortholog); INVOLVED IN BMP signaling pathway (ortholog); cell-abiotic substrate adhesion (ortholog); cellular response to dopamine (ortholog); PARTICIPATES IN interleuki n-3 signaling pathway; ASSOCIATED WITH cholestasis (ortholog); disease of cellular proliferation (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN centrosome (ortholog); INTERACTS WITH deoxynivalenol; graphene oxide | | | | Pig | 88 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18441448 | ID1 | inhibitor of DNA binding 1 | ENCODES a protein that exhibits identical protein binding (ortholog); proteasome binding (ortholog); transcription factor binding (ortholog); INVOLVED IN BMP signaling pathway (ortholog); cell-abiotic substrate adhesion (ortholog); cellular response to dopamine (ortholog); PARTICIPATES IN interleuki n-3 signaling pathway; ASSOCIATED WITH cholestasis (ortholog); disease of cellular proliferation (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN centrosome (ortholog) | | | | Green Monkey | 85 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 1623297 | Or13a18 | olfactory receptor family 13 subfamily A member 18 | Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors sha re a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008] | 7 | 140181253 | 140191037 | Mouse | 29 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1314646 | ARFGAP2 | ARF GTPase activating protein 2 | Predicted to enable GTPase activator activity. Predicted to be involved in COPI coating of Golgi vesicle. Located in Golgi apparatus; cytosol; and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025] | 11 | 47164301 | 47176879 | Human | 77 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 12169524 | ARFGAP2 | ADP ribosylation factor GTPase activating protein 2 | ENCODES a protein that exhibits GTPase activator activity (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN protein transport (inferred); vesicle-mediated transport (inferred); ASSOCIATED WITH Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN cyt oplasm (inferred); Golgi apparatus (inferred); Golgi membrane (inferred) | 18 | 42399743 | 42410044 | Dog | 13 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 1314647 | Arfgap2 | ARF GTPase activating protein 2 | This gene encodes a zinc-finger-containing GTPase-activating protein for ADP ribosylation factor 1 (ARF1), a small GTPase that plays a role in coatomer-mediated vesicular trafficking. This gene product stimulates the hydrolysis of ARF1-bound GTP, which may lead to dissociation of coatomer from Golgi -derived membranes to allow fusion with target membranes. It may regulate the retrograde transport from the Golgi complex to the endoplasmic reticulum. Expression of this gene has been shown to be controlled by inhibitor of DNA binding 1 (Id1). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene was identified on chromosome 6. [provided by RefSeq, Oct 2009] | 2 | 91095460 | 91107716 | Mouse | 95 | description | gene, protein-coding, REVIEWED [RefSeq] |