| 1308198 | Fosb | FosB proto-oncogene, AP-1 transcription factor subunit | ENCODES a protein that exhibits DNA-binding transcription factor activity; double-stranded DNA binding; sequence-specific DNA binding; INVOLVED IN behavioral response to cocaine; cellular response to hormone stimulus; female pregnancy; ASSOCIATED WITH alcohol dependence; alcohol use disorder; amphet amine abuse; FOUND IN cytosol; nucleus; nucleoplasm (ortholog); INTERACTS WITH (+)-pilocarpine; (R)-noradrenaline; (S)-amphetamine | 1 | 88082324 | 88089506 | Rat | 406 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1317837 | FOSB | FosB proto-oncogene, AP-1 transcription factor subunit | The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been impli cated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | 19 | 45467996 | 45475179 | Human | 413 | symbol , old_gene_name , COSMIC , name , description , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1317838 | Fosb | Fos B proto-oncogene, AP-1 transcription factor subunit | Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within cellular response to calcium ion. Pre dicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; gut; male reproductive gland or organ; skeleton; and skin. Orthologous to human FOSB (FosB proto-oncogene, AP-1 transcription factor subunit). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 19036621 | 19043970 | Mouse | 439 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8769766 | Fosb | FosB proto-oncogene, AP-1 transcription factor subunit | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN behavioral response to cocaine (ortholog); cellular response to calcium ion (ortholog); cellu lar response to hormone stimulus (ortholog); ASSOCIATED WITH alcohol dependence (ortholog); alcohol use disorder (ortholog); alcohol withdrawal syndrome (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | NW_004955555 | 2438864 | 2445846 | Chinchilla | 80 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 11810125 | FOSB | FosB proto-oncogene, AP-1 transcription factor subunit | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); double-stranded DNA binding (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN behavioral response to cocaine (ortholog); cellular response to calcium ion (ortholog); cellular response to hormone sti mulus (ortholog); ASSOCIATED WITH alcohol dependence (ortholog); alcohol use disorder (ortholog); alcohol withdrawal syndrome (ortholog); FOUND IN cytosol (ortholog); nucleus (ortholog) | 19 | 42416781 | 42424003 | Bonobo | 90 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 12339213 | FOSB | FosB proto-oncogene, AP-1 transcription factor subunit | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); double-stranded DNA binding (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN behavioral response to cocaine (ortholog); cellular response to calcium ion (ortholog); cellular response to hormone sti mulus (ortholog); ASSOCIATED WITH alcohol dependence (ortholog); alcohol use disorder (ortholog); alcohol withdrawal syndrome (ortholog); FOUND IN cytosol (ortholog); nucleus (ortholog) | 1 | 110088686 | 110092818 | Dog | 91 | symbol , old_gene_name , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12523452 | Fosb | FosB proto-oncogene, AP-1 transcription factor subunit | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); double-stranded DNA binding (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN behavioral response to cocaine (ortholog); cellular response to calcium ion (ortholog); cellular response to hormone sti mulus (ortholog); ASSOCIATED WITH alcohol dependence (ortholog); alcohol use disorder (ortholog); alcohol withdrawal syndrome (ortholog); FOUND IN cytosol (ortholog); nucleus (ortholog) | NW_004936706 | 1900954 | 1907567 | Squirrel | 89 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 625853129 | Fosb | FosB proto-oncogene, AP-1 transcription factor subunit | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN behavioral response to cocaine (ortholog); cellular response to calcium ion (ortholog); cellu lar response to hormone stimulus (ortholog); ASSOCIATED WITH alcohol dependence (ortholog); alcohol use disorder (ortholog); alcohol withdrawal syndrome (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | | | | Black Rat | 80 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18921081 | Fosb | FosB proto-oncogene, AP-1 transcription factor subunit | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); double-stranded DNA binding (ortholog); INVOLVED IN behavioral response to cocaine (ortholog); cellular response to calcium ion ( ortholog); cellular response to hormone stimulus (ortholog); ASSOCIATED WITH alcohol dependence (ortholog); alcohol use disorder (ortholog); alcohol withdrawal syndrome (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | | | | Naked Mole-Rat | 86 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 155244770 | fosb | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14289414 | FOSB | FosB proto-oncogene, AP-1 transcription factor subunit | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); double-stranded DNA binding (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN behavioral response to cocaine (ortholog); cellular response to calcium ion (ortholog); cellular response to hormone sti mulus (ortholog); ASSOCIATED WITH alcohol dependence (ortholog); alcohol use disorder (ortholog); alcohol withdrawal syndrome (ortholog); FOUND IN cytosol (ortholog); nucleus (ortholog); INTERACTS WITH ammonia | | | | Pig | 90 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 18619795 | FOSB | FosB proto-oncogene, AP-1 transcription factor subunit | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN behavioral response to cocaine (ortholog); cellular response to calcium ion (ortholog); cellu lar response to hormone stimulus (ortholog); ASSOCIATED WITH alcohol dependence (ortholog); alcohol use disorder (ortholog); alcohol withdrawal syndrome (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | | | | Green Monkey | 80 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 155237919 | fosb.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155243467 | fosb.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 18909317 | LOC101720400 | protein fosB pseudogene | | | | | Naked Mole-Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 735729 | FOS | Fos proto-oncogene, AP-1 transcription factor subunit | The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been imp licated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008] | 14 | 75278828 | 75282230 | Human | 1933 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 732196 | FOSL1 | FOS like 1, AP-1 transcription factor subunit | The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been impli cated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] | 11 | 65892049 | 65900545 | Human | 491 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 733116 | FOSL2 | FOS like 2, AP-1 transcription factor subunit | The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been impli cated as regulators of cell proliferation, differentiation, and transformation. [provided by RefSeq, Jul 2014] | 2 | 28392858 | 28417317 | Human | 388 | description | gene, protein-coding, REVIEWED [RefSeq] |