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37 records found for search term Eps15
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1305550Eps15epidermal growth factor receptor pathway substrate 15ENCODES a protein that exhibits identical protein binding (ortholog); polyubiquitin modification-dependent protein binding (ortholog); ubiquitin binding (ortholog); INVOLVED IN endocytic recycling; positive regulation of receptor recycling; postsynaptic neurotransmitter receptor internalization; PAR5129274487129374856Rat154symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1313642EPS15epidermal growth factor receptor pathway substrate 15This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple 15135426351519266Human169symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1313643Eps15epidermal growth factor receptor pathway substrate 15Enables identical protein binding activity and ubiquitin binding activity. Involved in ubiquitin-dependent endocytosis. Acts upstream of or within regulation of protein localization. Located in ciliary membrane; clathrin-coated pit; and clathrin-coated vesicle. Part of AP-2 adaptor complex. Is expre4109137372109245014Mouse208symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
8841814Eps15epidermal growth factor receptor pathway substrate 15ENCODES a protein that exhibits identical protein binding (ortholog); polyubiquitin modification-dependent protein binding (ortholog); ubiquitin binding (ortholog); INVOLVED IN clathrin coat assembly (ortholog); endocytic recycling (ortholog); Golgi to endosome transport (ortholog); PARTICIPATES IN NW_00495546475695707688098Chinchilla64symbolgene, protein-coding, MODEL [RefSeq]
11881079EPS15epidermal growth factor receptor pathway substrate 15ENCODES a protein that exhibits cadherin binding (inferred); calcium ion binding (inferred); identical protein binding (inferred); INVOLVED IN endocytic recycling (ortholog); positive regulation of receptor recycling (ortholog); postsynaptic neurotransmitter receptor internalization (ortholog); PART15059869250763585Bonobo82symbolgene, protein-coding, MODEL [RefSeq]
12115115EPS15epidermal growth factor receptor pathway substrate 15ENCODES a protein that exhibits calcium ion binding (inferred); identical protein binding (inferred); metal ion binding (inferred); INVOLVED IN endocytic recycling (ortholog); positive regulation of receptor recycling (ortholog); postsynaptic neurotransmitter receptor internalization (ortholog); PAR1598342859895755Dog83symbolgene, protein-coding, MODEL [RefSeq]
12726102Eps15epidermal growth factor receptor pathway substrate 15ENCODES a protein that exhibits identical protein binding (ortholog); polyubiquitin modification-dependent protein binding (ortholog); ubiquitin binding (ortholog); INVOLVED IN clathrin coat assembly (ortholog); endocytic recycling (ortholog); Golgi to endosome transport (ortholog); PARTICIPATES IN NW_00493652294389299486781Squirrel73symbolgene, protein-coding, MODEL [RefSeq]
14181669EPS15epidermal growth factor receptor pathway substrate 15ENCODES a protein that exhibits calcium ion binding (inferred); identical protein binding (inferred); metal ion binding (inferred); INVOLVED IN endocytic recycling (ortholog); positive regulation of receptor recycling (ortholog); postsynaptic neurotransmitter receptor internalization (ortholog); PARPig83symbolgene, protein-coding, MODEL [RefSeq]
18615123EPS15epidermal growth factor receptor pathway substrate 15ENCODES a protein that exhibits cadherin binding (inferred); calcium ion binding (inferred); identical protein binding (inferred); INVOLVED IN endocytic recycling (ortholog); positive regulation of receptor recycling (ortholog); postsynaptic neurotransmitter receptor internalization (ortholog); PARTGreen Monkey82symbolgene, protein-coding, MODEL [RefSeq]
18907907Eps15epidermal growth factor receptor pathway substrate 15ENCODES a protein that exhibits identical protein binding (ortholog); polyubiquitin modification-dependent protein binding (ortholog); ubiquitin binding (ortholog); INVOLVED IN clathrin coat assembly (ortholog); endocytic recycling (ortholog); Golgi to endosome transport (ortholog); PARTICIPATES IN Naked Mole-Rat78symbolgene, protein-coding, MODEL [RefSeq]
155254262eps15Tropical Clawed Frogsymbolgene, null
625840062Eps15epidermal growth factor receptor pathway substrate 15ENCODES a protein that exhibits identical protein binding (ortholog); polyubiquitin modification-dependent protein binding (ortholog); ubiquitin binding (ortholog); INVOLVED IN clathrin coat assembly (ortholog); endocytic recycling (ortholog); Golgi to endosome transport (ortholog); PARTICIPATES IN Black Rat64symbolgene, protein-coding, MODEL [RefSeq]
155251287eps15.LAfrican Clawed Frogsymbolgene, null
155241628eps15.SAfrican Clawed Frogsymbolgene, null
14700575EPS15-AS1EPS15 antisense RNA 115151827251579310Humansymbol , COSMIC , name , Human Proteome Mapgene, ncrna, VALIDATED [RefSeq]
1558414Eps15l1epidermal growth factor receptor pathway substrate 15-like 1Predicted to enable calcium ion binding activity. Involved in synaptic vesicle endocytosis. Part of clathrin coat of coated pit. Is active in presynapse. Is expressed in several structures, including alimentary system; liver; metanephros; nervous system; and sensory organ. Orthologous to human EPS1587309483473175410Mouse125symbol , old_gene_name , PhenoGen , description , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1351510EPN2epsin 2This gene encodes a protein which interacts with clathrin and adaptor-related protein complex 2, alpha 1 subunit. The protein is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery. The protein is thought to be involved in clathrin-171923736619336715Human113old_gene_namegene, protein-coding, VALIDATED [RefSeq]
1345399EPS15L1epidermal growth factor receptor pathway substrate 15 like 1Enables cadherin binding activity. Predicted to be involved in endosomal transport and synaptic vesicle endocytosis. Located in membrane. [provided by Alliance of Genome Resources, Apr 2025]191635524716472012Human96symbol , old_gene_name , COSMIC , Human Proteome Map , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1565708Eps15l1epidermal growth factor receptor pathway substrate 15-like 1ENCODES a protein that exhibits calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN synaptic vesicle endocytosis (ortholog); FOUND IN clathrin coat of coated pit (ortholog); presynapse (ortholog); INTERACTS WITH aconitine; cadmium dichloride; glyphosate161746033017573824Rat82symbol , old_gene_name , PhenoGengene, protein-coding, VALIDATED [RefSeq]
8703493Eps15l1epidermal growth factor receptor pathway substrate 15 like 1INVOLVED IN synaptic vesicle endocytosis (ortholog); FOUND IN clathrin coat of coated pit (ortholog); presynapse (ortholog)NW_00495552412640351309394Chinchilla13symbolgene, protein-coding, MODEL [RefSeq]
11895437EPS15L1epidermal growth factor receptor pathway substrate 15 like 1ENCODES a protein that exhibits cadherin binding (inferred); calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN endocytosis (inferred); endosomal transport (inferred); synaptic vesicle endocytosis (inferred); FOUND IN clathrin coat of coated pit (inferred); clathrin-coated pit191584296415959492Bonobo27symbolgene, protein-coding, MODEL [RefSeq]
12213869EPS15L1epidermal growth factor receptor pathway substrate 15 like 1ENCODES a protein that exhibits calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN endocytosis (inferred); synaptic vesicle endocytosis (inferred); FOUND IN clathrin coat of coated pit (inferred); clathrin-coated pit (inferred); cytoplasm (inferred)204606470946161535Dog27symbolgene, protein-coding, MODEL [RefSeq]
12732332Eps15l1epidermal growth factor receptor pathway substrate 15 like 1ENCODES a protein that exhibits cadherin binding (inferred); calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN endocytosis (inferred); endosomal transport (inferred); synaptic vesicle endocytosis (inferred); FOUND IN clathrin coat of coated pit (inferred); clathrin-coated pitNW_00493659641429514241719Squirrel27symbolgene, protein-coding, MODEL [RefSeq]
14096092EPS15L1epidermal growth factor receptor pathway substrate 15 like 1ENCODES a protein that exhibits calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN endocytosis (inferred); synaptic vesicle endocytosis (inferred); FOUND IN clathrin coat of coated pit (inferred); clathrin-coated pit (inferred); cytoplasm (inferred)Pig27symbolgene, protein-coding, MODEL [RefSeq]
18376548EPS15L1epidermal growth factor receptor pathway substrate 15 like 1ENCODES a protein that exhibits cadherin binding (inferred); calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN endocytosis (inferred); endosomal transport (inferred); synaptic vesicle endocytosis (inferred); FOUND IN clathrin coat of coated pit (inferred); clathrin-coated pitGreen Monkey27symbolgene, protein-coding, MODEL [RefSeq]
18924594Eps15l1epidermal growth factor receptor pathway substrate 15 like 1ENCODES a protein that exhibits cadherin binding (inferred); calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN synaptic vesicle endocytosis (ortholog); FOUND IN presynapse (ortholog)Naked Mole-Rat26symbolgene, protein-coding, MODEL [RefSeq]
155247068eps15l1Tropical Clawed Frogsymbolgene, null
626150088Eps15l1epidermal growth factor receptor pathway substrate 15 like 1INVOLVED IN synaptic vesicle endocytosis (ortholog); FOUND IN clathrin coat of coated pit (ortholog); presynapse (ortholog)Black Rat13symbolgene, protein-coding, MODEL [RefSeq]
1348027EPS15P1epidermal growth factor receptor pathway substrate 15 pseudogene 1INTERACTS WITH lipopolysaccharide; S-(1,2-dichlorovinyl)-L-cysteine; zinc atom74678199046783420Human5symbol , COSMIC , Human Proteome Map , old_gene_symbolgene, pseudo, INFERRED [RefSeq]
155247067eps15l1.LAfrican Clawed Frogsymbolgene, null
155244651eps15l1.SAfrican Clawed Frogsymbolgene, null
1319124EHD1EH domain containing 1This gene belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-binding EH domain was first noted in EPS15, a substrate for the epidermal growth factor receptor. The E116485164264879693Human224descriptiongene, protein-coding, REVIEWED [RefSeq]
1315293AGFG2ArfGAP with FG repeats 2This gene is a member of the HIV-1 Rev binding protein (HRB) family and encodes a protein with one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs. This protein interacts with Eps15 homology (EH) domains and plays a rol7100539203100568220Human107descriptiongene, protein-coding, REVIEWED [RefSeq]
1346487EHBP1EH domain binding protein 1This gene encodes an Eps15 homology domain binding protein. The encoded protein may play a role in endocytic trafficking. A single nucleotide polymorphism in this gene is associated with an aggressive form of prostate cancer. Alternate splicing results in multip26267387863046487Human143descriptiongene, protein-coding, REVIEWED [RefSeq]
737072ITSN1intersectin 1The protein encoded by this gene is a cytoplasmic membrane-associated protein that indirectly coordinates endocytic membrane traffic with the actin assembly machinery. In addition, the encoded protein may regulate the formation of clathrin-coated vesicles and could be involved in synaptic vesicle re213364250133899861Human255descriptiongene, protein-coding, REVIEWED [RefSeq]
1348962NUMBNUMB endocytic adaptor proteinThe protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15147327521673458546Human153descriptiongene, protein-coding, REVIEWED [RefSeq]
16564796AC020917.2novel transcript, antisense EPS15L1Humannamegene, lncrna