Eps15 (epidermal growth factor receptor pathway substrate 15) - Rat Genome Database

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Gene: Eps15 (epidermal growth factor receptor pathway substrate 15) Ictidomys tridecemlineatus
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Symbol: Eps15
Name: epidermal growth factor receptor pathway substrate 15
RGD ID: 12726102
Description: ENCODES a protein that exhibits identical protein binding (ortholog); polyubiquitin modification-dependent protein binding (ortholog); INVOLVED IN clathrin coat assembly (ortholog); endocytic recycling (ortholog); Golgi to endosome transport (ortholog); PARTICIPATES IN clathrin-dependent synaptic vesicle endocytosis; Notch signaling pathway; FOUND IN aggresome (ortholog); AP-2 adaptor complex (ortholog); apical plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: epidermal growth factor receptor pathway substrate 15, transcript variant X1; epidermal growth factor receptor pathway substrate 15, transcript variant X2; epidermal growth factor receptor substrate 15; epidermal growth factor receptor substrate 15-like; LOC110596890
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505865,928,976 - 66,023,422 (-)NCBI
SpeTri2.0NW_0049365229,438,929 - 9,486,781 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
Eps15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505865,928,976 - 66,023,422 (-)NCBI
SpeTri2.0NW_0049365229,438,929 - 9,486,781 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EPS15
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl151,354,263 - 51,519,266 (-)EnsemblGRCh38hg38GRCh38
GRCh38151,354,263 - 51,519,275 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37151,819,935 - 51,984,938 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36151,592,523 - 51,757,583 (-)NCBINCBI36hg18NCBI36
Build 34151,531,955 - 51,697,016NCBI
Celera150,106,464 - 50,271,514 (-)NCBI
Cytogenetic Map1p32.3NCBI
HuRef149,937,536 - 50,064,736 (-)NCBIHuRef
CHM1_1151,937,379 - 52,102,411 (-)NCBICHM1_1
Eps15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394109,137,372 - 109,245,014 (+)NCBIGRCm39mm39
GRCm39 Ensembl4109,137,465 - 109,245,014 (+)Ensembl
GRCm384109,280,175 - 109,387,817 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4109,280,268 - 109,387,817 (+)EnsemblGRCm38mm10GRCm38
MGSCv374108,952,880 - 109,060,422 (+)NCBIGRCm37mm9NCBIm37
MGSCv364108,778,235 - 108,883,626 (+)NCBImm8
Celera4107,626,627 - 107,727,939 (+)NCBICelera
Cytogenetic Map4C7NCBI
Eps15
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25124,045,865 - 124,146,221 (+)NCBImRatBN7.2
Rnor_6.0 Ensembl5128,923,934 - 129,022,054 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.05128,923,809 - 129,022,268 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05132,763,094 - 132,861,698 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45130,639,805 - 130,739,014 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15130,645,030 - 130,744,240 (+)NCBI
Celera5122,775,022 - 122,873,141 (+)NCBICelera
Cytogenetic Map5q34-q35NCBI
Eps15
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554647,569,566 - 7,688,098 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554647,569,570 - 7,688,098 (+)NCBIChiLan1.0ChiLan1.0
EPS15
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1152,097,387 - 52,223,533 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl152,097,387 - 52,223,533 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0150,598,692 - 50,763,585 (-)NCBIMhudiblu_PPA_v0panPan3
EPS15
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1159,834,285 - 9,895,755 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl159,787,260 - 9,893,540 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha159,904,456 - 10,047,227 (+)NCBI
ROS_Cfam_1.0159,877,844 - 10,020,742 (+)NCBI
UMICH_Zoey_3.1159,689,665 - 9,832,450 (+)NCBI
UNSW_CanFamBas_1.0159,778,543 - 9,921,371 (+)NCBI
UU_Cfam_GSD_1.0159,794,994 - 9,938,012 (+)NCBI
EPS15
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6160,653,890 - 160,801,288 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16160,653,818 - 160,792,516 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26148,356,480 - 148,494,390 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EPS15
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12081,439,017 - 81,599,626 (+)NCBI
ChlSab1.1 Ensembl2081,439,025 - 81,602,710 (+)Ensembl
Vero_WHO_p1.0NW_02366603335,638,865 - 35,801,433 (-)NCBI
Eps15
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248591,584,024 - 1,754,395 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005326085   ⟹   XP_005326142
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505865,928,976 - 65,976,014 (-)NCBI
SpeTri2.0NW_0049365229,440,263 - 9,486,781 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021726844   ⟹   XP_021582519
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505865,928,976 - 65,977,266 (-)NCBI
SpeTri2.0NW_0049365229,438,929 - 9,486,531 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040288661   ⟹   XP_040144595
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505865,928,976 - 66,023,422 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_005326142   ⟸   XM_005326085
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_021582519   ⟸   XM_021726844
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_040144595   ⟸   XM_040288661
- Peptide Label: isoform X1
Protein Domains
EF-hand   EH


Additional Information

Database Acc Id Source(s)
NCBI Gene Eps15 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-25 Eps15  epidermal growth factor receptor pathway substrate 15  LOC110596890  epidermal growth factor receptor substrate 15-like  Data Merged 737654 PROVISIONAL